BR112015031653A2 - síntese de poloxâmeros e poloxaminas insaturados etilenicamente polimerizáveis de radical livre - Google Patents

síntese de poloxâmeros e poloxaminas insaturados etilenicamente polimerizáveis de radical livre

Info

Publication number
BR112015031653A2
BR112015031653A2 BR112015031653A BR112015031653A BR112015031653A2 BR 112015031653 A2 BR112015031653 A2 BR 112015031653A2 BR 112015031653 A BR112015031653 A BR 112015031653A BR 112015031653 A BR112015031653 A BR 112015031653A BR 112015031653 A2 BR112015031653 A2 BR 112015031653A2
Authority
BR
Brazil
Prior art keywords
poloxamines
poloxamers
free radical
synthesis
polymerizable unsaturated
Prior art date
Application number
BR112015031653A
Other languages
English (en)
Inventor
Kumar Awasthi Alok
Satyanarayana Ganugapati
F Kunzler Jay
Rai Nooji Satheesha
Original Assignee
Bausch & Lomb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bausch & Lomb filed Critical Bausch & Lomb
Publication of BR112015031653A2 publication Critical patent/BR112015031653A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
    • C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
    • C08F290/06—Polymers provided for in subclass C08G
    • C08F290/062—Polyethers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
    • C08G65/332—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof
    • C08G65/3322—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof acyclic
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/337—Polymers modified by chemical after-treatment with organic compounds containing other elements
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/34—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives
    • C08G65/48—Polymers modified by chemical after-treatment

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Polyethers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Macromonomer-Based Addition Polymer (AREA)

Abstract

1/1 resumo “síntese de poloxâmeros e poloxaminas insaturados etilenicamente polimerizáveis de radical livre” um novo método sintético de formar poloxâmeros e poloxaminas funcionalizados de terminal de extremidade polimerizáveis de radical livre em lotes na escala comercial que usa um sistema binário de inibidores para eliminar a formação de impurezas de alto peso molecular. também foi surpreendentemente descoberto que as impurezas inorgânicas formadas durante o processo sintético na escala comercial são removidos pelo uso de materiais resinosos.
BR112015031653A 2013-06-18 2014-06-18 síntese de poloxâmeros e poloxaminas insaturados etilenicamente polimerizáveis de radical livre BR112015031653A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361836471P 2013-06-18 2013-06-18
PCT/US2014/042951 WO2014205084A1 (en) 2013-06-18 2014-06-18 Synthesis of free radical polmerizable ethylenically unsaturated poloxamers and poloxamines

Publications (1)

Publication Number Publication Date
BR112015031653A2 true BR112015031653A2 (pt) 2017-07-25

Family

ID=51168448

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015031653A BR112015031653A2 (pt) 2013-06-18 2014-06-18 síntese de poloxâmeros e poloxaminas insaturados etilenicamente polimerizáveis de radical livre

Country Status (12)

Country Link
US (1) US9309357B2 (pt)
EP (1) EP3010946B1 (pt)
JP (1) JP6159025B2 (pt)
KR (1) KR101767852B1 (pt)
CN (1) CN105308080B (pt)
AU (1) AU2014281549B2 (pt)
BR (1) BR112015031653A2 (pt)
CA (1) CA2914135C (pt)
ES (1) ES2659759T3 (pt)
MX (1) MX367343B (pt)
PL (1) PL3010946T3 (pt)
WO (1) WO2014205084A1 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018004335A2 (en) * 2016-06-29 2018-01-04 Holland Novochem Technical Coatings B.V. Catalytically active radical scavengers based on benzylic and allylic functionalities
CN112312791B (zh) 2018-06-27 2023-05-26 鲍希与洛姆伯股份有限公司 包装溶液
CN111285845B (zh) * 2020-02-11 2021-01-01 深圳厚存纳米药业有限公司 末端官能团化的泊洛沙胺衍生物
AU2021325693A1 (en) 2020-08-10 2023-04-20 Bausch + Lomb Ireland Limited Packaging solutions
CN116940662A (zh) 2021-03-10 2023-10-24 博士伦爱尔兰有限公司 不含防腐剂的隐形眼镜处理溶液
US12012238B2 (en) 2021-05-26 2024-06-18 Bausch + Lomb Ireland Limited Packaging solutions
CN115616096A (zh) * 2021-07-16 2023-01-17 张家港市国泰华荣化工新材料有限公司 有机硅产品中bht和mehq的测定方法
US20230159202A1 (en) 2021-11-23 2023-05-25 Bausch + Lomb Ireland Limited Method for making a preservative-free packaged ophthalmic device product
US20230266505A1 (en) 2022-02-24 2023-08-24 Bausch + Lomb Ireland Limited Ophthalmic devices
CN114948795B (zh) * 2022-07-08 2023-09-08 上海信悉智能技术有限公司 一种温敏感凝胶面膜液及其制备方法
US20240166971A1 (en) 2022-10-26 2024-05-23 Bausch + Lomb Ireland Limited Contact lens treating solution
US20240218291A1 (en) 2022-12-22 2024-07-04 Bausch + Lomb Ireland Limited Contact lens treating solution
US20240317988A1 (en) 2023-03-22 2024-09-26 Bausch + Lomb Ireland Limited Monofunctional silicone monomers and silicone hydrogels formed therefrom

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1109563A4 (en) 1998-08-04 2009-07-22 Madash Llp HEAT-SENSITIVE HYDROGELS WITH MODIFIED TERMINATION
US6517933B1 (en) 2000-01-18 2003-02-11 Nano-Tex, Llc Hybrid polymer materials
JP2004527291A (ja) 2001-03-20 2004-09-09 アイトゲノッシスシェ・テヒニッシュ・ホーホシューレ・ツューリヒ 生体材料として使用するための熱感受性ポリマーの二段階加工
JP2002296774A (ja) * 2001-03-30 2002-10-09 Fuji Photo Film Co Ltd 平版印刷版用原版
WO2003104302A1 (de) * 2002-06-01 2003-12-18 Basf Aktiengesellschaft (meth)acrylester von polyalkoxyliertem trimethylolpropan
US8197841B2 (en) * 2004-12-22 2012-06-12 Bausch & Lomb Incorporated Polymerizable surfactants and their use as device forming comonomers
DE102006049803A1 (de) * 2006-10-23 2008-04-30 Clariant International Limited Hydroxyfunktionelle, copolymerisierbare Polyalkylenglykol-Makromonomere, deren Herstellung und Verwendung
WO2009073374A2 (en) * 2007-12-03 2009-06-11 Bausch & Lomb Incorporated Method for inhibiting attachment of microorganisms to biomedical devices
US8293838B2 (en) * 2008-06-20 2012-10-23 Adhezion Biomedical, Llc Stable and sterile tissue adhesive composition with a controlled high viscosity
JP2013204001A (ja) * 2012-03-29 2013-10-07 Mitsubishi Chemicals Corp 活性エネルギー線硬化性樹脂組成物およびそれを用いた積層体

Also Published As

Publication number Publication date
CN105308080A (zh) 2016-02-03
MX2015016562A (es) 2016-03-31
US9309357B2 (en) 2016-04-12
US20140371481A1 (en) 2014-12-18
JP6159025B2 (ja) 2017-07-05
AU2014281549B2 (en) 2017-02-02
ES2659759T3 (es) 2018-03-19
EP3010946B1 (en) 2017-12-20
KR20160019536A (ko) 2016-02-19
CN105308080B (zh) 2017-06-09
JP2016524014A (ja) 2016-08-12
MX367343B (es) 2019-08-15
KR101767852B1 (ko) 2017-08-11
EP3010946A1 (en) 2016-04-27
PL3010946T3 (pl) 2018-06-29
CA2914135A1 (en) 2014-12-24
CA2914135C (en) 2017-11-14
WO2014205084A1 (en) 2014-12-24
AU2014281549A1 (en) 2016-01-07

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Legal Events

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B11D Dismissal acc. art. 38, par 2 of ipl - failure to pay fee after grant in time