BR112015008925A2 - preservação de propriedades de biomaterial e métodos de armazenamento - Google Patents

preservação de propriedades de biomaterial e métodos de armazenamento

Info

Publication number
BR112015008925A2
BR112015008925A2 BR112015008925A BR112015008925A BR112015008925A2 BR 112015008925 A2 BR112015008925 A2 BR 112015008925A2 BR 112015008925 A BR112015008925 A BR 112015008925A BR 112015008925 A BR112015008925 A BR 112015008925A BR 112015008925 A2 BR112015008925 A2 BR 112015008925A2
Authority
BR
Brazil
Prior art keywords
biomaterials
storage
biomaterial
methods
extracellular matrix
Prior art date
Application number
BR112015008925A
Other languages
English (en)
Other versions
BR112015008925B1 (pt
Inventor
G M Brockbank Kelvin
Original Assignee
Lifeline Scient Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lifeline Scient Inc filed Critical Lifeline Scient Inc
Publication of BR112015008925A2 publication Critical patent/BR112015008925A2/pt
Publication of BR112015008925B1 publication Critical patent/BR112015008925B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226—Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0655—Chondrocytes; Cartilage

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Rheumatology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

abstract described herein are enhanced compositions and methods for storing biomaterials. in certain aspects, these biomaterials include natural and engineered eukaryotic tissues. the methods described herein include storing these biomaterials in such a manner that reduces or prevents the loss of biomaterial properties (e.g., extracellular matrix integrity, cell viability, or a combination thereof) occurring either during storage or after removal of the biomaterial from storage. in certain aspects, these biomaterials will be stored in animal product-free solutions containing an agent that prevents or reduces the loss of extracellular matrix integrity. tradução do resumo resumo patente de invenção: "preservação de propriedades de biomaterial e métodos de armazenamento". são aqui descritos métodos e composições aprimoradas para armazenamento de biomateriais. em alguns aspectos, os biomateriais incluem tecidos eucariotas naturais e artificiais. os métodos descritos aqui incluem armazenamento destes biomateriais de modo a reduzir ou impedir que perda de propriedades dos biomateriais (por exemplo, integridade da matriz extracelular, viabilidade celular ou uma combinação dos mesmos) ocorra, quer durante armazenamento ou após remoção do biomaterial de armazenamento. em alguns aspectos, os biomateriais serão armazenados em soluções sem produtos de origem animal que contêm um agente que previne ou reduz a perda de integridade da matriz extracelular. 1/4
BR112015008925-9A 2012-10-18 2013-10-18 composição de armazenamento de biomateriais BR112015008925B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261715576P 2012-10-18 2012-10-18
US61/715,576 2012-10-18
PCT/US2013/065666 WO2014063041A1 (en) 2012-10-18 2013-10-18 Preservation of biomaterial properties and methods of storing

Publications (2)

Publication Number Publication Date
BR112015008925A2 true BR112015008925A2 (pt) 2017-07-04
BR112015008925B1 BR112015008925B1 (pt) 2021-02-02

Family

ID=49551751

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015008925-9A BR112015008925B1 (pt) 2012-10-18 2013-10-18 composição de armazenamento de biomateriais

Country Status (9)

Country Link
US (2) US20140113273A1 (pt)
EP (1) EP2908630B1 (pt)
JP (1) JP6374872B2 (pt)
CN (2) CN110326611B (pt)
AU (2) AU2013331126A1 (pt)
BR (1) BR112015008925B1 (pt)
CA (1) CA2927684C (pt)
HK (1) HK1212158A1 (pt)
WO (1) WO2014063041A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6921737B2 (ja) * 2014-08-01 2021-08-18 イスト・テクノロジーズ・インコーポレイテッドＩｓｔｏ Ｔｅｃｈｎｏｌｏｇｉｅｓ， Ｉｎｃ． 軟骨組成物及びプロテオグリカン含量の修正方法
CN105638641B (zh) * 2016-03-16 2018-05-29 麦重伟 葡甘露胶在标本保存中的应用及其使用方法
CN106047859B (zh) * 2016-06-02 2019-03-15 苏州大学 一种利用丝素蛋白对dna保存的方法及试剂盒
CN109566601A (zh) * 2018-12-29 2019-04-05 中国人民解放军第四军医大学 一种软骨保存液及其使用方法
US11369107B2 (en) * 2019-05-09 2022-06-28 Restoration Biologies LLC Live tissue storage solution
CN110558312B (zh) * 2019-10-09 2020-07-28 科瑞百奥泰州生物技术有限公司 一种软骨组织低温冷藏保存液及其应用
CN111657267B (zh) * 2020-06-17 2021-02-02 科瑞百奥泰州生物技术有限公司 一种用于软骨，肌腱，半月板保存的无冰晶冷冻保存液和冷冻方法
CN112293408A (zh) * 2020-09-30 2021-02-02 中国科学院苏州生物医学工程技术研究所 生物标本保存液及包含其的集标本采集和保存功能一体的系统
CN112514892B (zh) * 2020-12-25 2022-06-14 广州赛莱拉干细胞科技股份有限公司 一种外泌体冻存保护液及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05199868A (ja) * 1991-07-18 1993-08-10 Fuji Yakuhin Kogyo Kk ティシュ・インヒビター・オブ・メタロプロテイナーゼ含有組織培養用無血清培地と細胞増殖方法
WO1993002183A1 (en) 1991-07-18 1993-02-04 Fuji Yakuhin Kogyo Kabushiki Kaisha Serum-free tissue culture medium containing tissue inhibitor of metalloproteinase and method for cell growth
JP3157619B2 (ja) * 1992-08-19 2001-04-16 富士薬品工業株式会社 ティシュ・インヒビター・オブ・メタロプロテイナーゼ−２含有組織培養用無血清培地と細胞増殖方法
GB9714936D0 (en) * 1997-07-17 1997-09-17 Smith & Nephew Cell culture products
US20030181371A1 (en) 2001-12-28 2003-09-25 Angiotech Pharmaceuticals, Inc. Compositions and methods of using collajolie
WO2006057876A2 (en) * 2004-11-22 2006-06-01 Cedars-Sinai Medical Center Methods and solutions for tissue preservation
JP2009502179A (ja) * 2005-07-29 2009-01-29 インペリアル イノベーションズ リミテッド 化合物
CA2824551C (en) * 2011-01-12 2020-05-12 The Curators Of The University Of Missouri Tissue preservation system

Also Published As

Publication number Publication date
CN104837339A (zh) 2015-08-12
AU2017203616A1 (en) 2017-06-15
EP2908630A1 (en) 2015-08-26
WO2014063041A1 (en) 2014-04-24
AU2013331126A1 (en) 2015-06-04
AU2017203616B2 (en) 2019-01-17
CA2927684A1 (en) 2014-04-24
JP2015533505A (ja) 2015-11-26
CN110326611B (zh) 2022-04-26
JP6374872B2 (ja) 2018-08-15
CA2927684C (en) 2022-03-22
HK1212158A1 (en) 2016-06-10
US20200260720A1 (en) 2020-08-20
US20140113273A1 (en) 2014-04-24
US11930809B2 (en) 2024-03-19
BR112015008925B1 (pt) 2021-02-02
EP2908630B1 (en) 2018-07-25
CN110326611A (zh) 2019-10-15

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06I Publication of requirement cancelled [chapter 6.9 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA.

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 18/10/2013, OBSERVADAS AS CONDICOES LEGAIS.