BR112019001894A2 - kits para preparar uma composição fluida hemostática e método para preparar uma composição fluida hemostática com o kit - Google Patents

kits para preparar uma composição fluida hemostática e método para preparar uma composição fluida hemostática com o kit

Info

Publication number
BR112019001894A2
BR112019001894A2 BR112019001894A BR112019001894A BR112019001894A2 BR 112019001894 A2 BR112019001894 A2 BR 112019001894A2 BR 112019001894 A BR112019001894 A BR 112019001894A BR 112019001894 A BR112019001894 A BR 112019001894A BR 112019001894 A2 BR112019001894 A2 BR 112019001894A2
Authority
BR
Brazil
Prior art keywords
hemostatic
fluid composition
preparing
kit
hemostatic fluid
Prior art date
Application number
BR112019001894A
Other languages
English (en)
Other versions
BR112019001894B1 (pt
Inventor
De Gasperis Alexia
Moura Campos Doris
Centis Valérie
Spotnitz William
Original Assignee
Biomup
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomup filed Critical Biomup
Publication of BR112019001894A2 publication Critical patent/BR112019001894A2/pt
Publication of BR112019001894B1 publication Critical patent/BR112019001894B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0052—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/0066—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/008—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/23—Carbohydrates
    • A61L2300/232—Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/23—Carbohydrates
    • A61L2300/236—Glycosaminoglycans, e.g. heparin, hyaluronic acid, chondroitin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/418—Agents promoting blood coagulation, blood-clotting agents, embolising agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

a invenção refere-se a um kit para preparar uma composição fluida hemostática, que compreende: - um pó hemostático tendo uma composição que compreende: ? colágeno não reticulado do tipo fibrilar que compreende um teor de colágeno fibroso e/ ou colágeno fibrilar de pelo menos 70% em peso em relação ao peso total do colágeno; ? pelo menos um monossacarídeo; e ? pelo menos um glicosaminoglicano; - uma solução salina a ser misturada com o pó hemostático de modo a formar a composição fluida hemostática. a invenção também se refere a um método para preparar uma composição fluida hemostática com tal kit, que compreende as etapas de: a. fornecer o pó hemostático em um recipiente; b. adicionar uma quantidade da solução salina no recipiente que envolve o pó hemostático, fechar e agitar o dito recipiente a fim de promover a hidratação do pó hemostático de modo a formar a composição fluida hemostática.
BR112019001894-8A 2016-08-12 2017-08-11 Kit para preparar uma composição fluida hemostática e método para preparar uma composição fluida hemostática com o kit BR112019001894B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16184119.2 2016-08-12
EP16184119 2016-08-12
PCT/EP2017/070428 WO2018029340A1 (en) 2016-08-12 2017-08-11 Hemostatic flowable

Publications (2)

Publication Number Publication Date
BR112019001894A2 true BR112019001894A2 (pt) 2019-05-07
BR112019001894B1 BR112019001894B1 (pt) 2022-06-14

Family

ID=56684537

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112019001894-8A BR112019001894B1 (pt) 2016-08-12 2017-08-11 Kit para preparar uma composição fluida hemostática e método para preparar uma composição fluida hemostática com o kit

Country Status (14)

Country Link
US (1) US11052172B2 (pt)
EP (1) EP3496770B1 (pt)
JP (1) JP7039559B2 (pt)
CN (1) CN110087697A (pt)
AU (1) AU2017310470B2 (pt)
BR (1) BR112019001894B1 (pt)
CA (1) CA3032657A1 (pt)
DK (1) DK3496770T3 (pt)
ES (1) ES2882506T3 (pt)
HU (1) HUE055368T2 (pt)
IL (1) IL264716B (pt)
PL (1) PL3496770T3 (pt)
PT (1) PT3496770T (pt)
WO (1) WO2018029340A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102093839B1 (ko) * 2019-05-28 2020-05-04 (주)다림티센 지혈용 조성물 및 이를 포함하는 용기
WO2021202619A1 (en) * 2020-03-30 2021-10-07 Northeastern University Collagen nucleation inhibitors
CN114681658B (zh) * 2020-12-31 2023-03-14 广州迈普再生医学科技股份有限公司 纤维聚集体及其制备方法和应用
CN114288463B (zh) * 2021-12-13 2022-07-05 鹏拓生物科技(杭州)有限公司 一种流体胶原蛋白止血材料的研制方法

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3171072D1 (en) 1981-06-25 1985-07-25 Stroetmann M Serapharm Enriched plasma derivative for promoting wound sealing and wound covering
US4515637A (en) 1983-11-16 1985-05-07 Seton Company Collagen-thrombin compositions
US4942153A (en) 1987-02-03 1990-07-17 Fernandez Helen M Skin moisturizing product and process
US5263984A (en) 1987-07-20 1993-11-23 Regen Biologics, Inc. Prosthetic ligaments
US4891359A (en) * 1988-12-08 1990-01-02 Johnson & Johnson Patient Care, Inc. Hemostatic collagen paste composition
US5413571A (en) * 1992-07-16 1995-05-09 Sherwood Medical Company Device for sealing hemostatic incisions
IT1263394B (it) 1993-07-30 1996-08-05 Fidia Advanced Biopolymers Srl Composizioni farmaceutiche per uso topico a base di acido ialuronico e suoi derivati
DE19520575A1 (de) 1995-06-06 1996-12-12 Permselect Ges Fuer Zellstrukt Hautwirksame Kombination von Mucopolysacchariden
JP2002514960A (ja) 1997-06-18 2002-05-21 コヘージョン テクノロジーズ，インコーポレイテッド トロンビンおよびミクロフィブリルコラーゲンを含む組成物、ならびにその調製および使用の方法
US7691829B2 (en) 1998-03-24 2010-04-06 Petito George D Composition and method for healing tissues
US20050208114A1 (en) 1998-03-24 2005-09-22 Petito George D Composition and method for healing tissues
DE69933775T2 (de) 1998-08-20 2007-10-04 3M Innovative Properties Co., St. Paul Sprühverband und wirkstoffabgabesystem
AU2001266926A1 (en) * 2000-06-16 2002-01-02 University Of Medicine And Dentistry Of New Jersey Hemostatic compositions, devices and methods
AT411326B (de) 2000-06-20 2003-12-29 Biering Wolfgang Hämostatische collagen-pellets
AT412445B (de) 2000-06-20 2005-03-25 Biering Wolfgang Flüssiges collagen-hämostatikum
CN2442681Y (zh) * 2000-08-18 2001-08-15 刘高东 药用喷雾罐
US7119062B1 (en) * 2001-02-23 2006-10-10 Neucoll, Inc. Methods and compositions for improved articular surgery using collagen
US20030003157A1 (en) 2001-06-06 2003-01-02 University Of Medicine & Dentistry Of New Jersey Collagen compositions and methods for making and using the same
JP3805654B2 (ja) 2001-08-29 2006-08-02 株式会社ネクスト 止血・癒着防止性のバイオポリマーの微細粒子
WO2003026709A1 (en) 2001-09-26 2003-04-03 Mbs Multination Business Services (G.B.) Ltd. Liquid mixture for use as a dressing spray
JP4668510B2 (ja) * 2001-09-29 2011-04-13 持田製薬株式会社 可撓性容器入り局所止血用医薬組成物
DE60234469D1 (de) * 2001-12-21 2009-12-31 Ferrosan As Hämostatische garnitur, verfahren zum zubereiten eines hämostatischen mittels und verfahren zur blutstillung
EP1501558A1 (de) 2002-05-08 2005-02-02 Rheinisch-Westfälische Technische Hochschule Aachen (RWTH) Resorbierbare pharmazeutische formulierung zur kontinuierlichen thrombinfreisetzung
US20060019868A1 (en) * 2004-01-30 2006-01-26 Pendharkar Sanyog M Hemostatic compositions and devices
US7927626B2 (en) 2003-08-07 2011-04-19 Ethicon, Inc. Process of making flowable hemostatic compositions and devices containing such compositions
EP1660013A4 (en) 2003-08-26 2011-07-20 Gel Del Technologies Inc BIOMATERIAL AND PROTEIN BIOCOACERVATES, METHODS OF MAKING AND USING THEM
CN1554448A (zh) 2003-12-23 2004-12-15 张淑荣 壳聚糖明胶聚乙烯醇生物止血敷料
DE602005022554D1 (de) * 2004-01-30 2010-09-09 Ferrosan As Hämostatische sprays und zusammensetzungen
WO2005087182A1 (ja) 2004-03-17 2005-09-22 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo 機能性粉体
EP1580229A1 (en) 2004-03-22 2005-09-28 Warner-Lambert Company Llc Biopolymer compositons and products thereof
US20080021374A1 (en) 2004-05-13 2008-01-24 Sousaku Kawata Apparatus for Hemostasis and Adhesion Prevention for Use in Endoscopic Surgery
US8021684B2 (en) 2004-07-09 2011-09-20 Ferrosan Medical Devices A/S Haemostatic composition comprising hyaluronic acid
US7429386B2 (en) * 2004-09-03 2008-09-30 Allergan, Inc. Stretch mark treatment
MY142987A (en) 2005-06-08 2011-02-14 Hayashibara Biochem Lab Solution for tissue adhesion prevention and method for tissue adhesion prevention
CN1709507A (zh) 2005-06-29 2005-12-21 肖春 外用复方止血镇痛消炎药
CN101272790A (zh) 2005-09-22 2008-09-24 特罗比奥股份公司 稳定的蛋白酶组合物
US8932560B2 (en) 2007-09-04 2015-01-13 University of Maryland, College Parke Advanced functional biocompatible polymeric matrix used as a hemostatic agent and system for damaged tissues and cells
US8304595B2 (en) 2007-12-06 2012-11-06 Nanosys, Inc. Resorbable nanoenhanced hemostatic structures and bandage materials
DK2252335T3 (da) 2008-03-03 2013-07-08 Omrix Biopharmaceuticals Ltd Gelatinesvamp omfattende en aktiv bestanddel, fremstilling og anvendelse deraf
BRPI1010275A2 (pt) * 2009-03-27 2017-05-16 Johnson & Johnson Consumer Companies Inc particulados galvânicos binários e terciários e métodos de fabricação dos mesmos
FR2944706B1 (fr) 2009-04-28 2012-08-24 Biom Up Nouveaux materiaux en collagene et procedes d'obtention.
CN101757614B (zh) 2010-02-22 2012-04-04 苏州汇涵医用科技发展有限公司 止血剂及其制备方法
CN101837143A (zh) 2010-04-22 2010-09-22 胡堃 一种药物缓释止血组合物及制备方法
WO2012122044A2 (en) 2011-03-04 2012-09-13 Orthovita, Inc. Flowable collagen-based hemostat and methods of use
EP3922261A1 (en) * 2011-04-27 2021-12-15 Biom'up France Sas Hemostatic compositions
PL2701611T3 (pl) * 2011-04-27 2016-04-29 Biomup Dozownik biomedycznego proszku hemostatycznego
EP3010419B1 (en) * 2013-06-21 2020-05-20 Ferrosan Medical Devices A/S Vacuum expanded dry composition and syringe for retaining same
CN105769554A (zh) * 2014-12-23 2016-07-20 天津博众纳德生物科技有限公司 带有两翼的可吸收止血粉的瓶子

Also Published As

Publication number Publication date
IL264716B (en) 2021-09-30
US11052172B2 (en) 2021-07-06
JP2019524313A (ja) 2019-09-05
NZ750516A (en) 2023-10-27
RU2019105215A (ru) 2020-09-14
ES2882506T3 (es) 2021-12-02
PT3496770T (pt) 2021-08-10
RU2019105215A3 (pt) 2020-10-09
HUE055368T2 (hu) 2021-11-29
AU2017310470A1 (en) 2019-02-28
DK3496770T3 (da) 2021-06-21
AU2017310470B2 (en) 2021-12-16
US20190167840A1 (en) 2019-06-06
EP3496770A1 (en) 2019-06-19
CN110087697A (zh) 2019-08-02
CA3032657A1 (en) 2018-02-15
BR112019001894B1 (pt) 2022-06-14
EP3496770B1 (en) 2021-05-19
JP7039559B2 (ja) 2022-03-22
PL3496770T3 (pl) 2021-09-27
WO2018029340A1 (en) 2018-02-15

Similar Documents

Publication Publication Date Title
BR112019001894A2 (pt) kits para preparar uma composição fluida hemostática e método para preparar uma composição fluida hemostática com o kit
BR112013027567A2 (pt) composição hemostática, método para preparar uma composição hemostática, composição e kit
BR112018007415A2 (pt) antioxidante reativo, composição e método para vedar pelo menos uma porção de uma peça
BR112018011430A2 (pt) processo de deslignificação parcial e de preenchimento de um material lignocelulósico, e estrutura de material compósito suscetível de ser obtido por esse processo
BR112016013195A2 (pt) Composições para a higiene bucal compreendendo carbonato de cálcio e uma argila
BR112017022845A2 (pt) neoepítopos de câncer
BR112016006828A2 (pt) dispositivo de fabricação de folha, método para fabricação de folha, folha fabricada pelo mesmo, composição usando o mesmo e recipiente de acomodação para o mesmo
BR112022001029A2 (pt) Método de preparação de matriz extracelular descelularizada livre de detergente, ecm descelularizada livre de detergente, método de preparação de uma biotinta primária, biotinta primária, método de preparação de uma biotinta vascular, biotinta vascular, estrutura tridimensional, e, método de preparação de uma estrutura tridimensional
BR112016007573A2 (pt) material de lignocelulose, método para produção e uso do mesmo
BR112013018613A2 (pt) composição, e, método para preparar uma composição
BR112017018028A2 (pt) método de produção de compostos lignocelulósicos
BR112015025029A2 (pt) composição para uso como uma argamassa de enchimento de dois componentes compreendendo silicato extraído
AR094640A1 (es) Composiciones alimenticias de pseudohogazas
BR112015021533A2 (pt) composição curável, método para vedar uma abertura e abertura vedada
MX351347B (es) Composicion de sellado endodontico.
BR112014026088A2 (pt) produto de tratamento de tecidos, estojo, método de fabricação de um produto de tratamento de tecidos, método de tratamento, e uso do produto de tratamento de tecidos
BR112015032570A2 (pt) lipoenchimento com células-tronco derivadas de tecido adiposo expandidas ex vivo para preenchimento de mama estético ou para preenchimento e/ou rejuvenescimento facial
BR112017002836A2 (pt) composições de terpolímero com clareza e brilho aprimorados
AR093736A1 (es) Metodo de preparacion de un material compuesto lignocelulosico
BR112017011332A2 (pt) método de produção de lignina com quantidade reduzida de substâncias odoríferas
BR112022001795A2 (pt) Composição de cloreto de polivinila, métodos para preparar a composição e para preparar um artigo compósito polimérico, e, artigo compósito polimérico
BR112017013084A2 (pt) composições de polietileno com propriedades ópticas melhoradas
BR212022015839U2 (pt) Composição alimentícia líquida que compreende proteínas de ervilha e nenhuma proteína láctea
BR112013004262A2 (pt) processo para a preparação de composições ou sistemas de cimento/argamassa/concreto, carga para composições de cimento, composições de cimento, argamassa ou concreto, aplicação (ões) do processo ou das composições ou da carga, e, produtos ou elementos de cimento
BR102018004721A8 (pt) Composição com baixo teor de resíduos

Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: BIOM'UP FRANCE SAS (FR)

B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 11/08/2017, OBSERVADAS AS CONDICOES LEGAIS