BR112014031853A2 - métodos para a inativação viral e bacteriana em meios de cultura celular - Google Patents

métodos para a inativação viral e bacteriana em meios de cultura celular

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Publication number
BR112014031853A2
BR112014031853A2 BR112014031853A BR112014031853A BR112014031853A2 BR 112014031853 A2 BR112014031853 A2 BR 112014031853A2 BR 112014031853 A BR112014031853 A BR 112014031853A BR 112014031853 A BR112014031853 A BR 112014031853A BR 112014031853 A2 BR112014031853 A2 BR 112014031853A2
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BR
Brazil
Prior art keywords
methods
viral
cell culture
culture media
bacterial inactivation
Prior art date
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BR112014031853A
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English (en)
Other versions
BR112014031853B1 (pt
Inventor
Prashad Hardayal
Bourret Justin
Ken Shiratori Masaru
Kim Michael
Iverson Raquel
David Kiss Robert
Charaniya Salim
Original Assignee
Genentech Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48746128&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112014031853(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of BR112014031853A2 publication Critical patent/BR112014031853A2/pt
Publication of BR112014031853B1 publication Critical patent/BR112014031853B1/pt

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    • C—CHEMISTRY; METALLURGY
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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04—Inactivation or attenuation; Producing viral sub-units
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/36—Adaptation or attenuation of cells
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/12—Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
    • C12N2500/14—Calcium; Ca chelators; Calcitonin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin
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    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/42—Organic phosphate, e.g. beta glycerophosphate
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    • C12N2500/60—Buffer, e.g. pH regulation, osmotic pressure
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14061—Methods of inactivation or attenuation
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    • C12N2760/12061—Methods of inactivation or attenuation
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    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16061—Methods of inactivation or attenuation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18061—Methods of inactivation or attenuation
    • C—CHEMISTRY; METALLURGY
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    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20061—Methods of inactivation or attenuation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/16011—Caliciviridae
    • C12N2770/16061—Methods of inactivation or attenuation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32061—Methods of inactivation or attenuation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/36011—Togaviridae
    • C12N2770/36061—Methods of inactivation or attenuation

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

resumo patente de invenção: "métodos para a inativação viral e bacteriana em meios de cultura celular". a presente invenção refere-se a métodos de inativação viral que utilizam o tratamento de curto período de tempo em alta temperatura (htst) e o ajuste de vários parâmetros, de modo que a geração de precipitado e de deposições de precipitado seja reduzida e/ou minimizada.
BR112014031853-0A 2012-06-20 2013-06-20 Métodos para a inativação viral e bacteriana em meios de cultura celular BR112014031853B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261662349P 2012-06-20 2012-06-20
US61/662,349 2012-06-20
US13/844,051 US9493744B2 (en) 2012-06-20 2013-03-15 Methods for viral inactivation and other adventitious agents
US13/844,051 2013-03-15
PCT/US2013/046756 WO2013192395A1 (en) 2012-06-20 2013-06-20 Methods for inactivation of viruses and bacteria in cell culture media

Publications (2)

Publication Number Publication Date
BR112014031853A2 true BR112014031853A2 (pt) 2017-06-27
BR112014031853B1 BR112014031853B1 (pt) 2021-09-14

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ID=48746128

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BR112014031853-0A BR112014031853B1 (pt) 2012-06-20 2013-06-20 Métodos para a inativação viral e bacteriana em meios de cultura celular

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US (4) US9493744B2 (pt)
EP (2) EP3205715A1 (pt)
JP (3) JP6607779B2 (pt)
KR (2) KR102095073B1 (pt)
CN (2) CN115491340A (pt)
AR (1) AR091508A1 (pt)
AU (2) AU2013277118B2 (pt)
BR (1) BR112014031853B1 (pt)
CA (1) CA2875997C (pt)
DK (1) DK2864471T3 (pt)
ES (1) ES2625060T3 (pt)
HK (1) HK1210215A1 (pt)
HU (1) HUE032812T2 (pt)
IL (1) IL236144B (pt)
MX (2) MX365381B (pt)
MY (1) MY192975A (pt)
PL (1) PL2864471T3 (pt)
RU (1) RU2685203C2 (pt)
SG (2) SG11201408473UA (pt)
SI (1) SI2864471T1 (pt)
WO (1) WO2013192395A1 (pt)
ZA (1) ZA201409172B (pt)

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AR091508A1 (es) 2015-02-11
MX2019006336A (es) 2022-06-27
JP2015523865A (ja) 2015-08-20
SG10201707017XA (en) 2017-09-28
PL2864471T3 (pl) 2017-07-31
CN115491340A (zh) 2022-12-20
HUE032812T2 (en) 2017-11-28
KR102095073B1 (ko) 2020-03-30
HK1210215A1 (en) 2016-04-15
CA2875997A1 (en) 2013-12-27
MX2014015751A (es) 2015-04-10
CA2875997C (en) 2020-07-21
RU2685203C2 (ru) 2019-04-16
US10184106B2 (en) 2019-01-22
EP3205715A1 (en) 2017-08-16
EP2864471B1 (en) 2017-03-08
BR112014031853B1 (pt) 2021-09-14
CN104603261A (zh) 2015-05-06
JP6607779B2 (ja) 2019-11-20
EP2864471A1 (en) 2015-04-29
US20170159010A1 (en) 2017-06-08
US20130344570A1 (en) 2013-12-26
KR20150020695A (ko) 2015-02-26
IL236144B (en) 2020-06-30
MY192975A (en) 2022-09-20
JP2020062019A (ja) 2020-04-23
US20230159886A1 (en) 2023-05-25
SI2864471T1 (sl) 2017-05-31
ZA201409172B (en) 2017-09-27
JP2018019711A (ja) 2018-02-08
MX365381B (es) 2019-05-31
AU2013277118A1 (en) 2015-01-22
SG11201408473UA (en) 2015-01-29
ES2625060T3 (es) 2017-07-18
AU2019202400A1 (en) 2019-05-02
AU2013277118B2 (en) 2019-05-02
DK2864471T3 (en) 2017-05-08
US9493744B2 (en) 2016-11-15
US20200216799A1 (en) 2020-07-09
RU2015101506A (ru) 2016-08-10
WO2013192395A1 (en) 2013-12-27
KR20200034829A (ko) 2020-03-31
IL236144A0 (en) 2015-01-29

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