BR112014018192A8 - método e kit para detecção de células tumorais circulantes 5t4-positivas, bem como métodos de diagnóstico de câncer 5t4-positivo e de seleção para atividade e eficácia de conjugado fármaco-anticorpo para tratamento de câncer - Google Patents
método e kit para detecção de células tumorais circulantes 5t4-positivas, bem como métodos de diagnóstico de câncer 5t4-positivo e de seleção para atividade e eficácia de conjugado fármaco-anticorpo para tratamento de câncerInfo
- Publication number
- BR112014018192A8 BR112014018192A8 BR112014018192A BR112014018192A BR112014018192A8 BR 112014018192 A8 BR112014018192 A8 BR 112014018192A8 BR 112014018192 A BR112014018192 A BR 112014018192A BR 112014018192 A BR112014018192 A BR 112014018192A BR 112014018192 A8 BR112014018192 A8 BR 112014018192A8
- Authority
- BR
- Brazil
- Prior art keywords
- positive
- detecting
- tumor cells
- efficacy
- kit
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
- G01N33/5759—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70589—CD45
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
- Oncology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261590066P | 2012-01-24 | 2012-01-24 | |
| US201361753665P | 2013-01-17 | 2013-01-17 | |
| PCT/IB2013/050547 WO2013111054A1 (en) | 2012-01-24 | 2013-01-22 | Methods for detecting 5t4-positive circulating tumor cells and methods of diagnosis of 5t4-positive cancer in a mammalian subject |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112014018192A8 true BR112014018192A8 (pt) | 2021-03-02 |
Family
ID=47844410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014018192A BR112014018192A8 (pt) | 2012-01-24 | 2013-01-22 | método e kit para detecção de células tumorais circulantes 5t4-positivas, bem como métodos de diagnóstico de câncer 5t4-positivo e de seleção para atividade e eficácia de conjugado fármaco-anticorpo para tratamento de câncer |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US10254286B2 (https=) |
| EP (1) | EP2807485B1 (https=) |
| JP (1) | JP6254951B2 (https=) |
| KR (1) | KR101716555B1 (https=) |
| CN (1) | CN104094116B (https=) |
| AU (2) | AU2013213301A1 (https=) |
| BR (1) | BR112014018192A8 (https=) |
| CA (1) | CA2861437C (https=) |
| ES (1) | ES2724232T3 (https=) |
| IL (1) | IL233543B (https=) |
| IN (1) | IN2014DN07019A (https=) |
| MX (1) | MX361058B (https=) |
| RU (1) | RU2646498C2 (https=) |
| WO (1) | WO2013111054A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2803804B2 (ja) | 1992-08-21 | 1998-09-24 | 株式会社長澤製作所 | ボタン錠 |
| EP3045918B1 (en) | 2009-10-21 | 2017-12-06 | The Scripps Research Institute | Method of using non-rare cells to detect rare cells |
| US8956859B1 (en) | 2010-08-13 | 2015-02-17 | Aviex Technologies Llc | Compositions and methods for determining successful immunization by one or more vaccines |
| EA201691352A1 (ru) * | 2013-12-30 | 2016-11-30 | Дзе Скриппс Рисерч Инститьют | Диагностика рака легкого с помощью циркулирующих опухолевых клеток |
| EA201691496A1 (ru) | 2014-01-27 | 2016-12-30 | Эпик Сайенсиз, Инк. | Диагностика биомаркеров рака предстательной железы с помощью циркулирующих опухолевых клеток |
| EA201691682A1 (ru) * | 2014-02-21 | 2017-02-28 | Эпик Сайенсиз, Инк. | Способы анализирования редких циркулирующих в крови клеток |
| WO2015155345A1 (en) * | 2014-04-11 | 2015-10-15 | Medimmune Limited | Antibodies and antibody-drug conjugates |
| EA201692223A1 (ru) * | 2014-05-09 | 2017-04-28 | Дзе Скриппс Рисерч Инститьют | Композиции и способы жидкостной биопсии меланомы |
| CA2959072C (en) * | 2014-08-25 | 2025-12-09 | Creatv Microtech, Inc. | Use of circulating cell biomarkers in the blood for detection and diagnosis of diseases and methods of isolating them |
| CN113552350B (zh) * | 2015-04-21 | 2024-10-11 | 基因泰克公司 | 用于前列腺癌分析的组合物和方法 |
| KR102771841B1 (ko) * | 2015-11-06 | 2025-02-24 | 벤타나 메디컬 시스템즈, 인코포레이티드 | 대표 진단법 |
| KR20170099738A (ko) | 2016-02-23 | 2017-09-01 | 노을 주식회사 | 접촉식 염색 패치 및 그 제조 방법 |
| KR102406596B1 (ko) * | 2016-02-23 | 2022-06-10 | 노을 주식회사 | 패치를 이용하는 ctc 진단 방법 및 장치 |
| KR102478639B1 (ko) | 2016-02-23 | 2022-12-19 | 노을 주식회사 | 표지 물질을 저장하는 패치, 이를 이용하는 조직 진단 방법 및 장치 |
| US10371610B2 (en) | 2016-02-23 | 2019-08-06 | Noul Co., Ltd. | Contact-type patch, staining method using the same, and manufacturing method thereof |
| KR102045069B1 (ko) * | 2016-02-23 | 2019-11-15 | 노을 주식회사 | 패치를 이용하는 ctc 진단 방법 및 장치 |
| SG11201909218RA (en) | 2017-04-03 | 2019-11-28 | Hoffmann La Roche | Antibodies binding to steap-1 |
| EP3646010A4 (en) * | 2017-06-27 | 2020-11-11 | Qcdx, Llc | QUANTITATIVE LIQUID BIOPSY DIAGNOSTIC SYSTEM AND METHOD |
| CN107918013A (zh) * | 2017-09-25 | 2018-04-17 | 浙江天科高新技术发展有限公司 | 化学发光酶免测定循环肿瘤细胞中K‑Ras蛋白的方法及试剂盒 |
| JP7678424B2 (ja) | 2018-05-10 | 2025-05-16 | 学校法人順天堂 | 画像解析方法、装置、コンピュータプログラム、及び深層学習アルゴリズムの生成方法 |
| WO2020086882A1 (en) * | 2018-10-24 | 2020-04-30 | Northwestern University | Tumor cell aggregation inhibitors' for treating cancer |
| JP7381003B2 (ja) * | 2019-04-26 | 2023-11-15 | 学校法人順天堂 | 疾患解析を支援する方法、装置、及びコンピュータプログラム、並びにコンピュータアルゴリズムを訓練する方法、装置、及びプログラム |
| EP4445141A1 (en) | 2021-12-07 | 2024-10-16 | Epic Sciences, Inc. | Enhanced characterization of breast cancer |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4391904A (en) | 1979-12-26 | 1983-07-05 | Syva Company | Test strip kits in immunoassays and compositions therein |
| US5869053A (en) | 1988-03-04 | 1999-02-09 | Cancer Research Campaign Technology, Ltd. | 5T4 antigen from human trophoblasts |
| WO1989007947A1 (en) | 1988-03-04 | 1989-09-08 | Cancer Research Campaign Technology Limited | Improvements relating to antigens |
| EP1717248A1 (en) | 1997-06-04 | 2006-11-02 | Oxford Biomedica (UK) Limited | Tumor targeted vector |
| JP2003515323A (ja) | 1999-11-18 | 2003-05-07 | オックスフォード バイオメディカ（ユーケイ）リミテッド | 抗 体 |
| GB0126378D0 (en) | 2001-11-02 | 2002-01-02 | Oxford Biomedica Ltd | Antigen |
| US7305112B2 (en) | 2002-10-15 | 2007-12-04 | The Scripps Research Institute | Method of converting rare cell scanner image coordinates to microscope coordinates using reticle marks on a sample media |
| PE20100251A1 (es) * | 2004-09-10 | 2010-04-10 | Wyeth Corp | Anticuerpos anti-5t4 humanizados y conjugados anticuerpo anti-5t4/calicheamicina |
| EP1984030B1 (en) | 2006-01-30 | 2013-05-08 | The Scripps Research Institute | Methods for detection of circulating tumor cells and methods of diagnosis of cancer in a mammalian subject |
| MY148763A (en) | 2006-03-10 | 2013-05-31 | Wyeth Corp | Anti-5t4 antibodies and uses thereof |
| US20100233694A1 (en) | 2007-04-16 | 2010-09-16 | On-O-ity, Inc | Devices and methods for diagnosing, prognosing, or theranosing a condition by enriching rare cells |
| GB0822836D0 (en) * | 2008-12-15 | 2009-01-21 | Oxford Biomedica Ltd | Method |
| AU2010229924B2 (en) | 2009-03-24 | 2016-07-21 | Plus Therapeutics Inc. | Devices and methods of cell capture and analysis |
| ES2405605T3 (es) | 2009-03-27 | 2013-05-31 | Wyeth Llc | Células iniciadoras de tumores y procedimientos de uso de las mismas |
| JP2013504064A (ja) | 2009-09-03 | 2013-02-04 | ザ スクリプス リサーチ インスティチュート | 循環腫瘍細胞を分類する方法 |
| EP3045918B1 (en) | 2009-10-21 | 2017-12-06 | The Scripps Research Institute | Method of using non-rare cells to detect rare cells |
| WO2011127219A1 (en) * | 2010-04-06 | 2011-10-13 | Caris Life Sciences Luxembourg Holdings | Circulating biomarkers for disease |
| EP2591363B1 (en) | 2010-07-07 | 2017-09-20 | The Regents Of The University Of Michigan | Diagnosis and treatment of breast cancer |
| DK2694111T3 (en) | 2011-04-01 | 2016-10-10 | Wyeth Llc | Antibody pharmaceutical conjugates |
-
2013
- 2013-01-22 AU AU2013213301A patent/AU2013213301A1/en not_active Abandoned
- 2013-01-22 BR BR112014018192A patent/BR112014018192A8/pt not_active Application Discontinuation
- 2013-01-22 MX MX2014008928A patent/MX361058B/es active IP Right Grant
- 2013-01-22 JP JP2014553836A patent/JP6254951B2/ja not_active Expired - Fee Related
- 2013-01-22 CA CA2861437A patent/CA2861437C/en not_active Expired - Fee Related
- 2013-01-22 KR KR1020147020394A patent/KR101716555B1/ko not_active Expired - Fee Related
- 2013-01-22 IN IN7019DEN2014 patent/IN2014DN07019A/en unknown
- 2013-01-22 CN CN201380006333.9A patent/CN104094116B/zh not_active Expired - Fee Related
- 2013-01-22 US US14/374,083 patent/US10254286B2/en not_active Expired - Fee Related
- 2013-01-22 EP EP13708526.2A patent/EP2807485B1/en active Active
- 2013-01-22 ES ES13708526T patent/ES2724232T3/es active Active
- 2013-01-22 RU RU2014127474A patent/RU2646498C2/ru active
- 2013-01-22 WO PCT/IB2013/050547 patent/WO2013111054A1/en not_active Ceased
-
2014
- 2014-07-07 IL IL233543A patent/IL233543B/en active IP Right Grant
-
2018
- 2018-08-24 AU AU2018220154A patent/AU2018220154A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| IL233543B (en) | 2018-02-28 |
| WO2013111054A1 (en) | 2013-08-01 |
| MX2014008928A (es) | 2014-10-24 |
| RU2646498C2 (ru) | 2018-03-05 |
| US20150017661A1 (en) | 2015-01-15 |
| CN104094116B (zh) | 2017-05-31 |
| KR101716555B1 (ko) | 2017-03-14 |
| CA2861437A1 (en) | 2013-08-01 |
| IL233543A0 (en) | 2014-08-31 |
| CN104094116A (zh) | 2014-10-08 |
| RU2014127474A (ru) | 2016-03-20 |
| IN2014DN07019A (https=) | 2015-04-10 |
| ES2724232T3 (es) | 2019-09-09 |
| MX361058B (es) | 2018-11-23 |
| AU2013213301A1 (en) | 2014-07-17 |
| JP2015507190A (ja) | 2015-03-05 |
| CA2861437C (en) | 2018-08-21 |
| JP6254951B2 (ja) | 2017-12-27 |
| KR20140100580A (ko) | 2014-08-14 |
| HK1202923A1 (en) | 2015-10-09 |
| AU2018220154A1 (en) | 2018-09-13 |
| EP2807485A1 (en) | 2014-12-03 |
| US10254286B2 (en) | 2019-04-09 |
| EP2807485B1 (en) | 2019-03-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112014018192A8 (pt) | método e kit para detecção de células tumorais circulantes 5t4-positivas, bem como métodos de diagnóstico de câncer 5t4-positivo e de seleção para atividade e eficácia de conjugado fármaco-anticorpo para tratamento de câncer | |
| WO2012056236A3 (en) | Analytical methods and arrays for use in the identification of agents inducing sensitization in human skin | |
| MX2013009380A (es) | Metodo para diagnosticar cancer y kit de diagnostico usando medicion de actividad de celulas nk. | |
| EP2209495A4 (en) | TAZ / WWTR1 FOR THE DIAGNOSIS AND TREATMENT OF CANCER | |
| BR112013010015A2 (pt) | aparelho e método para detecção não invasiva de doenças que afetam as propriedades estruturais em tecidos biológicos | |
| EP3236262A3 (en) | Surrogate functional diagnostics test for cancer | |
| WO2013138522A3 (en) | Methods for assessing effectiveness and monitoring oncolytic virus treatment | |
| MX342791B (es) | Ensayo elisa para la detección de vegf. | |
| WO2015071876A3 (en) | Use of microrna markers for diagnosis of thyroid tumors and a diagnostic panel containing such markers. | |
| BR112015023120A2 (pt) | método para identificar um indivíduo com uma doença ou disfunção, método para prever a responsividade de um indivíduo com uma doença ou disfunção, método para determinar a probabilidade de que um indivíduo com uma doença ou disfunção exibirá benefício do tratamento, método para selecionar uma terapia, usos de um antagonista de ligação do eixo pd-l1, ensaio para identificar um indivíduo com uma doença, kit de diagnóstico, método para avaliar uma resposta ao tratamento e método para monitorar a resposta de um indivíduo tratado | |
| TN2014000454A1 (en) | Anti-gcc antibody molecules and use of same to test for susceptibility to gcc-targeted therapy | |
| MX2009012722A (es) | Variantes geneticas sobre chr 5p12 y 10q26 como marcadores para el uso en la evaluacion del riesgo, diagnostico, pronostico y tratamiento del cancer de mama. | |
| BR112014003999A2 (pt) | anticorpo isolado que se liga a um epítopo próximo da membrana de mcsp humano, ácido nucleico isolado, célula hospedeira, método de produção de um anticorpo, imunoconjugado, formulação farmacêutica, uso do anticorpo, método de tratamento de indivíduos portadores de câncer, método de undução da lise celular em indivíduos e teste imuno-histoquímico de mcsp | |
| WO2008091814A3 (en) | Assessment of asthma and allergen-dependent gene expression | |
| EA201691352A1 (ru) | Диагностика рака легкого с помощью циркулирующих опухолевых клеток | |
| WO2008015599A3 (en) | A method of in vivio detection and/or diagnosis of cancer using fluorescence based dna image cytometry | |
| BR112012027151A8 (pt) | método para detectar ou identificar uma sequência de polinucleotídeo viral infeccioso ou genômico em uma célula de mamífero, tecido ou fluido biológico, método para detectar ou seguir a presença viral, replicação viral ou rearranjos genômicos virais em uma célula de mamífero, método para avaliação da eficácia de um tratamento antiviral, conjunto de sondas, kit para realizar molelular combing e materiais biológicos. | |
| WO2009052159A3 (en) | Methods for selecting active agents for cancer treatment | |
| WO2010099137A3 (en) | In situ methods for monitoring the emt status of tumor cells in vivo | |
| BR112014031958A2 (pt) | bag3 como marcador de tecido e soro bioquímico | |
| MX2009001070A (es) | Uso de proteina con actividad inhibidora de melanoma (mia) como un indicador temprano para la respuesta terapeutica en melanoma. | |
| ES2570609T3 (es) | Método para someter a ensayo la aminoacilasa 1 para el diagnóstico in vitro del cáncer colorrectal | |
| WO2017053763A3 (en) | ANDROGEN RECEPTOR VARIANT 7 AS A BIOMARKER FOR TREATMENT SELECTION IN PATIENTS WITH METASTATIC CASTRATION RESISTANT PROSTATE CANCER (mCRPC) | |
| WO2014146035A3 (en) | Compositions and methods for cancer diagnosis | |
| Williams et al. | Clinical translation of a novel microfilter technology Capture, characterization and culture of circulating tumor cells |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |