BR112014017630A2 - - Google Patents
Info
- Publication number
- BR112014017630A2 BR112014017630A2 BR112014017630A BR112014017630A BR112014017630A2 BR 112014017630 A2 BR112014017630 A2 BR 112014017630A2 BR 112014017630 A BR112014017630 A BR 112014017630A BR 112014017630 A BR112014017630 A BR 112014017630A BR 112014017630 A2 BR112014017630 A2 BR 112014017630A2
- Authority
- BR
- Brazil
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12153457 | 2012-02-01 | ||
| EP12182505 | 2012-08-31 | ||
| PCT/EP2013/051604 WO2013113663A1 (en) | 2012-02-01 | 2013-01-29 | Method for the detection of a binding partner of a multispecific binder |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112014017630A2 true BR112014017630A2 (US07585860-20090908-C00112.png) | 2017-06-20 |
| BR112014017630A8 BR112014017630A8 (pt) | 2017-07-11 |
Family
ID=47624068
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014017630A BR112014017630A8 (pt) | 2012-02-01 | 2013-01-29 | Métodos para a determinação de presença e/ou da quantidade de um antígeno |
Country Status (11)
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2859268A1 (en) | 2012-02-01 | 2013-08-08 | F. Hoffmann-La Roche Ag | Method for the detection of a binding partner of a multispecific binder |
| RU2636822C2 (ru) | 2012-07-13 | 2017-11-28 | Ф.Хоффманн-Ля Рош Аг | Способ обнаружения мультиспецифического связывающего агента |
| EP3066469B1 (en) | 2013-11-05 | 2017-10-11 | Roche Diagnostics GmbH | A method for determining the total amount and/or concentration of an analyte in the presence of a binding molecule as well as kits, compositions and uses relating thereto |
| CN104109197B (zh) * | 2013-11-13 | 2017-05-10 | 叶森 | 一种双识别抗体片段的制备方法及其应用 |
| UA124925C2 (en) | 2015-10-02 | 2021-12-15 | Hoffmann La Roche | Bispecific antibodies specific for pd1 and tim3 |
| JP6734919B2 (ja) * | 2015-10-02 | 2020-08-05 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 同時結合を測定するための細胞ベースのｆｒｅｔアッセイ法 |
| PE20191494A1 (es) | 2017-04-03 | 2019-10-21 | Hoffmann La Roche | Inmunoconjugados de un anticuerpo anti-pd-1 con un il-2 mutante o con il-15 |
| TWI690538B (zh) | 2017-04-05 | 2020-04-11 | 瑞士商赫孚孟拉羅股份公司 | 特異性結合至pd1至lag3的雙特異性抗體 |
| US20210231654A1 (en) | 2018-06-04 | 2021-07-29 | Chugai Seiyaku Kabushiki Kaisha | Method for detecting complex |
| EP3969907A1 (en) | 2019-05-13 | 2022-03-23 | F. Hoffmann-La Roche AG | Interference-suppressed pharmacokinetic immunoassay |
| WO2022065052A1 (ja) * | 2020-09-24 | 2022-03-31 | 株式会社Ｊｖｃケンウッド | 捕捉用抗体、固相担体、検出用抗体、固相担体粒子、並びに検出対象物質の測定キット及び測定方法 |
| CN117805397A (zh) * | 2024-02-29 | 2024-04-02 | 军科正源（北京）药物研究有限责任公司 | 检测游离vegf的方法 |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5219730A (en) | 1982-09-28 | 1993-06-15 | New York University | Idiotype-anti-idiotype immunoassay |
| US4828981A (en) | 1983-08-24 | 1989-05-09 | Synbiotics Corporation | Immunoassays for determining Dirofilaria immitis infection using antiidiotype monoclonal antibody reagents |
| EP0170302A1 (fr) | 1984-06-27 | 1986-02-05 | l'Association internationale à but scientifique, dite: Institut international de pathologie cellulaire et moléculaire | Procédé de dosage immunologique d'une substance dans un échantillon liquide au moyen d'anticorps anti-idiotypiques |
| US5238808A (en) | 1984-10-31 | 1993-08-24 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
| WO1987002778A1 (en) | 1985-10-22 | 1987-05-07 | Cooper-Lipotech | Solid-phase liposome immunoassay system |
| WO1990005301A1 (en) | 1988-11-03 | 1990-05-17 | Igen, Inc. | Electrochemiluminescent assays |
| US5068088A (en) | 1988-11-03 | 1991-11-26 | Igen, Inc. | Method and apparatus for conducting electrochemiluminescent measurements |
| IL100866A (en) | 1991-02-06 | 1995-10-31 | Igen Inc | Luminescence test method and device based on magnetic tiny particles, containing many magnets |
| DE69332377T2 (de) | 1992-07-13 | 2003-07-03 | Bionebraska, Inc. | Verfahren zur modifizierung rekombinanter polypeptide |
| JPH097096A (ja) | 1995-06-20 | 1997-01-10 | Alpine Electron Inc | 緊急車両接近時の報知方法 |
| JPH0975096A (ja) * | 1995-09-14 | 1997-03-25 | Snow Brand Milk Prod Co Ltd | ラクトフェリンの測定法 |
| AU757691B2 (en) | 1997-11-21 | 2003-03-06 | Inverness Medical Switzerland Gmbh | Improvements in or relating to displacement assays |
| US6753189B1 (en) * | 1998-06-04 | 2004-06-22 | Mizuho Medy Co., Ltd. | Detection apparatus and method for the same |
| JPH11352129A (ja) * | 1998-06-04 | 1999-12-24 | Mizuho Medeii:Kk | 検出装置及び検出方法 |
| ATE315789T1 (de) * | 1999-11-16 | 2006-02-15 | Genentech Inc | Elisa für vegf |
| GB0007088D0 (en) * | 2000-03-23 | 2000-05-17 | Torsana A S | Detection of immunological memory determining the position of loci of pathologyand therapeutic t-cell conjugates |
| US6984494B2 (en) | 2000-08-15 | 2006-01-10 | Genentech, Inc. | Analytical method |
| US7341837B2 (en) | 2003-09-02 | 2008-03-11 | Lawton Robert L | Soluble analyte detection and amplification |
| EP1861708A2 (en) * | 2005-03-08 | 2007-12-05 | Tanox, Inc. | Methods for determining the bivalency of protein and antibody therapeutics |
| US7494776B2 (en) * | 2005-07-07 | 2009-02-24 | Beckman Coulter, Inc. | Labeled complementary oligonucleotides to detect oligonucleotide-linked ligands |
| JP2009501913A (ja) | 2005-07-21 | 2009-01-22 | ゲンマブ エー／エス | Ｆｃ受容体と結合する抗体原薬に関する効力アッセイ |
| CN101268372A (zh) * | 2005-07-21 | 2008-09-17 | 根马布股份公司 | 与fc受体结合的抗体药物的药效测定 |
| KR101551984B1 (ko) * | 2006-10-04 | 2015-09-09 | 제넨테크, 인크. | Ｖｅｇｆ용 ｅｌｉｓａ |
| EP1917854A1 (en) | 2006-11-06 | 2008-05-07 | F. Hoffmann-La Roche Ag | Method for producing anti idiotypic antibodies |
| US20090162359A1 (en) | 2007-12-21 | 2009-06-25 | Christian Klein | Bivalent, bispecific antibodies |
| US8227577B2 (en) | 2007-12-21 | 2012-07-24 | Hoffman-La Roche Inc. | Bivalent, bispecific antibodies |
| US9266967B2 (en) | 2007-12-21 | 2016-02-23 | Hoffmann-La Roche, Inc. | Bivalent, bispecific antibodies |
| US8242247B2 (en) | 2007-12-21 | 2012-08-14 | Hoffmann-La Roche Inc. | Bivalent, bispecific antibodies |
| EP2297209A4 (en) * | 2008-06-03 | 2012-08-01 | Abbott Lab | IMMUNOGLOBULINS WITH TWO VARIABLE DOMAINS AND USES THEREOF |
| WO2010042031A1 (en) * | 2008-10-07 | 2010-04-15 | Gyros Patent Ab | Semi-sequential assay for detection of an analyte in a sample |
| RU2598248C2 (ru) | 2009-04-02 | 2016-09-20 | Роше Гликарт Аг | Полиспецифичные антитела, включающие антитела полной длины и одноцепочечные фрагменты fab |
| PL2417156T3 (pl) | 2009-04-07 | 2015-07-31 | Roche Glycart Ag | Trójwartościowe, bispecyficzne przeciwciała |
| CA2761233A1 (en) | 2009-05-27 | 2010-12-02 | F. Hoffmann-La Roche Ag | Tri- or tetraspecific antibodies |
| US9676845B2 (en) | 2009-06-16 | 2017-06-13 | Hoffmann-La Roche, Inc. | Bispecific antigen binding proteins |
| US8703132B2 (en) | 2009-06-18 | 2014-04-22 | Hoffmann-La Roche, Inc. | Bispecific, tetravalent antigen binding proteins |
| KR101536388B1 (ko) * | 2009-10-19 | 2015-07-22 | 에프. 호프만-라 로슈 아게 | 비-교차반응성 항-ＩｇＧ 항체 |
| CN102207504A (zh) * | 2011-03-23 | 2011-10-05 | 北京华创远航科技有限公司 | 一种酶联检测试剂盒及其制备方法 |
| JP6203747B2 (ja) * | 2011-12-19 | 2017-09-27 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 多特異性結合体の遊離結合パートナーの検出方法 |
| CA2859268A1 (en) | 2012-02-01 | 2013-08-08 | F. Hoffmann-La Roche Ag | Method for the detection of a binding partner of a multispecific binder |
| US20130231462A1 (en) * | 2012-02-27 | 2013-09-05 | Bio-Rad Laboratories, Inc. | Anti-immune complex antibodies |
| RU2636822C2 (ru) | 2012-07-13 | 2017-11-28 | Ф.Хоффманн-Ля Рош Аг | Способ обнаружения мультиспецифического связывающего агента |
-
2013
- 2013-01-29 CA CA2859268A patent/CA2859268A1/en not_active Abandoned
- 2013-01-29 KR KR1020147021674A patent/KR20140128314A/ko not_active Application Discontinuation
- 2013-01-29 WO PCT/EP2013/051604 patent/WO2013113663A1/en active Application Filing
- 2013-01-29 CN CN201380007278.5A patent/CN104105966B/zh active Active
- 2013-01-29 BR BR112014017630A patent/BR112014017630A8/pt not_active IP Right Cessation
- 2013-01-29 EP EP13701628.3A patent/EP2810074B1/en active Active
- 2013-01-29 RU RU2014133701A patent/RU2620563C2/ru not_active IP Right Cessation
- 2013-01-29 CN CN201610880999.2A patent/CN106443016B/zh active Active
- 2013-01-29 MX MX2014008762A patent/MX349661B/es active IP Right Grant
- 2013-01-29 JP JP2014555164A patent/JP2015507193A/ja active Pending
-
2014
- 2014-08-01 US US14/449,437 patent/US9945869B2/en active Active
-
2015
- 2015-04-01 HK HK15103324.4A patent/HK1202921A1/xx unknown
-
2017
- 2017-08-29 JP JP2017163827A patent/JP6502441B2/ja active Active
-
2018
- 2018-03-16 US US15/923,773 patent/US10761097B2/en active Active
-
2019
- 2019-03-20 JP JP2019052527A patent/JP6678792B2/ja active Active
-
2020
- 2020-07-31 US US16/945,730 patent/US20210055304A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| HK1202921A1 (en) | 2015-10-09 |
| CA2859268A1 (en) | 2013-08-08 |
| EP2810074A1 (en) | 2014-12-10 |
| JP2017223710A (ja) | 2017-12-21 |
| US20180328942A1 (en) | 2018-11-15 |
| WO2013113663A1 (en) | 2013-08-08 |
| US20140342382A1 (en) | 2014-11-20 |
| JP2019113564A (ja) | 2019-07-11 |
| JP2015507193A (ja) | 2015-03-05 |
| RU2620563C2 (ru) | 2017-05-26 |
| BR112014017630A8 (pt) | 2017-07-11 |
| CN106443016A (zh) | 2017-02-22 |
| MX349661B (es) | 2017-08-08 |
| MX2014008762A (es) | 2014-08-27 |
| JP6502441B2 (ja) | 2019-04-17 |
| EP2810074B1 (en) | 2017-08-23 |
| US20210055304A1 (en) | 2021-02-25 |
| KR20140128314A (ko) | 2014-11-05 |
| JP6678792B2 (ja) | 2020-04-08 |
| US9945869B2 (en) | 2018-04-17 |
| RU2014133701A (ru) | 2016-03-27 |
| CN104105966B (zh) | 2016-10-26 |
| CN104105966A (zh) | 2014-10-15 |
| CN106443016B (zh) | 2019-08-13 |
| US10761097B2 (en) | 2020-09-01 |
Similar Documents
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2551 DE 26-11-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |