BR112014008303A2 - alimentação contínua controlada pré-programada sem feedback de culturas celulares - Google Patents

alimentação contínua controlada pré-programada sem feedback de culturas celulares

Info

Publication number
BR112014008303A2
BR112014008303A2 BR112014008303A BR112014008303A BR112014008303A2 BR 112014008303 A2 BR112014008303 A2 BR 112014008303A2 BR 112014008303 A BR112014008303 A BR 112014008303A BR 112014008303 A BR112014008303 A BR 112014008303A BR 112014008303 A2 BR112014008303 A2 BR 112014008303A2
Authority
BR
Brazil
Prior art keywords
feedback
cell cultures
continuous feed
controlled continuous
programmed controlled
Prior art date
Application number
BR112014008303A
Other languages
English (en)
Portuguese (pt)
Inventor
Lin Henry
Bezaire Jeremy
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of BR112014008303A2 publication Critical patent/BR112014008303A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/32—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of substances in solution
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/38—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of metabolites or enzymes in the cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/40—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pressure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BR112014008303A 2011-09-16 2012-09-14 alimentação contínua controlada pré-programada sem feedback de culturas celulares BR112014008303A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161535809P 2011-09-16 2011-09-16
PCT/US2012/055552 WO2013040444A1 (en) 2011-09-16 2012-09-14 Pre-programmed non-feedback controlled continuous feeding of cell cultures

Publications (1)

Publication Number Publication Date
BR112014008303A2 true BR112014008303A2 (pt) 2017-04-11

Family

ID=46964067

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014008303A BR112014008303A2 (pt) 2011-09-16 2012-09-14 alimentação contínua controlada pré-programada sem feedback de culturas celulares

Country Status (16)

Country Link
US (1) US9803166B2 (https=)
EP (1) EP2756069B1 (https=)
JP (4) JP2014526265A (https=)
KR (1) KR101710766B1 (https=)
CN (1) CN103946366B (https=)
AU (1) AU2012308335A1 (https=)
BR (1) BR112014008303A2 (https=)
CA (1) CA2846905A1 (https=)
EA (1) EA201490502A1 (https=)
ES (1) ES2862576T3 (https=)
IL (1) IL231032A0 (https=)
MX (1) MX356956B (https=)
SG (1) SG11201400656SA (https=)
TW (1) TWI583788B (https=)
WO (1) WO2013040444A1 (https=)
ZA (1) ZA201401655B (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU765203B2 (en) 1999-04-19 2003-09-11 Shionogi & Co., Ltd. Sulfonamide derivatives having oxadiazole rings
AU2015269365A1 (en) 2014-06-04 2016-12-15 Amgen Inc. Methods for harvesting mammalian cell cultures
PL3865563T3 (pl) 2014-11-25 2024-01-29 Corning Incorporated Materiały i sposoby do przedłużania pożywki do hodowli komórkowej
CA2969225C (en) 2014-12-01 2023-08-22 Amgen Inc. Process for manipulating the level of glycan content of a glycoprotein
WO2016183016A1 (en) * 2015-05-08 2016-11-17 Flownamics Analytical Instruments, Inc. Method & apparatus for continuous automated perfusion system harvesting from in-situ filtration probe
WO2021097281A1 (en) 2019-11-15 2021-05-20 Lonza Ltd Process and system for producing an inoculum
US20230287335A1 (en) 2020-07-30 2023-09-14 Amgen Inc. Cell culture media and methods of making and using the same
CN112553044A (zh) * 2020-12-10 2021-03-26 上海奥浦迈生物科技股份有限公司 一种生物反应器细胞培养进样口用防堵塞装置
KR20250056246A (ko) * 2022-10-13 2025-04-25 가부시키가이샤 히타치세이사쿠쇼 배양 장치의 제어 방법, 및 세포 배양을 수반하는 배양 장치의 제어 방법

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5629202A (en) 1994-07-19 1997-05-13 Development Center For Biotechnology Computer-controlled bioreactor system for enzymatic synthesis of L-tryptophan
ATE241695T1 (de) * 1996-03-13 2003-06-15 Delta Biotechnology Ltd Gärungs-steuerungssysteme
WO1998041611A1 (en) 1997-03-20 1998-09-24 Regents Of The University Of Minnesota Process for the continuous culture of cells
CN1678731A (zh) * 2002-08-27 2005-10-05 范德比尔特大学 多室生物反应器
DE102004007658B4 (de) * 2004-02-17 2008-12-18 Bioceuticals Arzneimittel Ag Verfahren zur Herstellung von rekombinanten Proteinen in eukaryontischen Wirtszellen
CN1778903A (zh) 2005-09-29 2006-05-31 华东理工大学 一种动物细胞高密度连续灌注培养方法
WO2007071072A1 (en) * 2005-12-22 2007-06-28 Corporation De L'ecole Polytechnique De Montreal High-rate perfusion bioreactor
JP2007202500A (ja) * 2006-02-03 2007-08-16 Hitachi Ltd 培養槽の運転制御装置
WO2008136398A1 (ja) 2007-04-26 2008-11-13 Chugai Seiyaku Kabushiki Kaisha 高濃度アミノ酸含有培地を用いた細胞の培養方法

Also Published As

Publication number Publication date
TWI583788B (zh) 2017-05-21
WO2013040444A1 (en) 2013-03-21
AU2012308335A1 (en) 2014-03-13
JP2022058710A (ja) 2022-04-12
EA201490502A1 (ru) 2014-06-30
IL231032A0 (en) 2014-03-31
MX356956B (es) 2018-06-21
CN103946366B (zh) 2017-08-11
SG11201400656SA (en) 2014-04-28
ES2862576T3 (es) 2021-10-07
KR101710766B1 (ko) 2017-02-27
TW201326387A (zh) 2013-07-01
KR20140044396A (ko) 2014-04-14
US20140295545A1 (en) 2014-10-02
US9803166B2 (en) 2017-10-31
EP2756069A1 (en) 2014-07-23
JP2020022492A (ja) 2020-02-13
JP2014526265A (ja) 2014-10-06
EP2756069B1 (en) 2021-01-27
MX2014003134A (es) 2014-04-25
JP2017029162A (ja) 2017-02-09
CA2846905A1 (en) 2013-03-21
ZA201401655B (en) 2014-12-23
CN103946366A (zh) 2014-07-23

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]