BR112014006822B1 - Proteína de ligação ao antígeno cd27l, composição compreendendo uma proteína de ligação ao antígeno cd27l, ácido nucleico isolado, vetor de expressão, célula hospedeira recombinante procariótica, método de preparação de um conjugado de droga e anticorpo cd27l e uso de uma proteína de ligação ao antígeno cd27l - Google Patents

Proteína de ligação ao antígeno cd27l, composição compreendendo uma proteína de ligação ao antígeno cd27l, ácido nucleico isolado, vetor de expressão, célula hospedeira recombinante procariótica, método de preparação de um conjugado de droga e anticorpo cd27l e uso de uma proteína de ligação ao antígeno cd27l Download PDF

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Publication number
BR112014006822B1
BR112014006822B1 BR112014006822-4A BR112014006822A BR112014006822B1 BR 112014006822 B1 BR112014006822 B1 BR 112014006822B1 BR 112014006822 A BR112014006822 A BR 112014006822A BR 112014006822 B1 BR112014006822 B1 BR 112014006822B1
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Brazil
Prior art keywords
seq
cd27l
amino acid
antigen
binding protein
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BR112014006822-4A
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English (en)
Portuguese (pt)
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BR112014006822A2 (pt
Inventor
John M. Delaney
William Christian Fanslow Iii
Chadwick Terence King
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Amgen Inc.
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Application filed by Amgen Inc. filed Critical Amgen Inc.
Publication of BR112014006822A2 publication Critical patent/BR112014006822A2/pt
Publication of BR112014006822B1 publication Critical patent/BR112014006822B1/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2875—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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    • C—CHEMISTRY; METALLURGY
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Physical Education & Sports Medicine (AREA)
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  • Transplantation (AREA)
  • Obesity (AREA)
  • Neurosurgery (AREA)
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BR112014006822-4A 2011-09-22 2012-09-20 Proteína de ligação ao antígeno cd27l, composição compreendendo uma proteína de ligação ao antígeno cd27l, ácido nucleico isolado, vetor de expressão, célula hospedeira recombinante procariótica, método de preparação de um conjugado de droga e anticorpo cd27l e uso de uma proteína de ligação ao antígeno cd27l BR112014006822B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161538024P 2011-09-22 2011-09-22
US61/538,024 2011-09-22
PCT/US2012/056429 WO2013043933A2 (en) 2011-09-22 2012-09-20 Cd27l antigen binding proteins

Publications (2)

Publication Number Publication Date
BR112014006822A2 BR112014006822A2 (pt) 2017-04-04
BR112014006822B1 true BR112014006822B1 (pt) 2021-05-18

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BR112014006822-4A BR112014006822B1 (pt) 2011-09-22 2012-09-20 Proteína de ligação ao antígeno cd27l, composição compreendendo uma proteína de ligação ao antígeno cd27l, ácido nucleico isolado, vetor de expressão, célula hospedeira recombinante procariótica, método de preparação de um conjugado de droga e anticorpo cd27l e uso de uma proteína de ligação ao antígeno cd27l

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US (3) US8987422B2 (enExample)
EP (1) EP2758437B1 (enExample)
JP (2) JP6251678B2 (enExample)
KR (1) KR102007055B1 (enExample)
CN (1) CN104136461B (enExample)
AP (1) AP2014007588A0 (enExample)
AR (1) AR093186A1 (enExample)
AU (2) AU2012312274B2 (enExample)
BR (1) BR112014006822B1 (enExample)
CA (1) CA2849318C (enExample)
CL (2) CL2014000699A1 (enExample)
CO (1) CO7020862A2 (enExample)
CR (1) CR20140169A (enExample)
EA (2) EA027900B1 (enExample)
ES (1) ES2806146T3 (enExample)
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EP2686347B1 (en) 2011-03-16 2018-05-02 argenx BVBA Antibodies to cd70
CN104136461B (zh) * 2011-09-22 2021-06-08 安姆根有限公司 Cd27l抗原结合蛋白
TWI679019B (zh) * 2013-04-29 2019-12-11 法商賽諾菲公司 抗ｉｌ－４／抗ｉｌ－１３之雙特異性抗體調配物
EP3151857A4 (en) * 2014-06-03 2018-04-18 Merck Sharp & Dohme Corp. Anti-blys antibodies
US10391168B1 (en) 2014-08-22 2019-08-27 University Of Bern Anti-CD70 combination therapy
SG11201701328XA (en) 2014-09-02 2017-03-30 Immunogen Inc Methods for formulating antibody drug conjugate compositions
AU2016206457B2 (en) 2015-01-16 2021-11-11 Juno Therapeutics, Inc. Antibodies and chimeric antigen receptors specific for ROR1
TWI717375B (zh) * 2015-07-31 2021-02-01 德商安美基研究（慕尼黑）公司 Ｃｄ７０及ｃｄ３抗體構築體
CA3012827A1 (en) 2016-02-02 2017-08-10 Fred Hutchinson Cancer Research Center Anti-ror1 antibodies and uses thereof
JOP20190055A1 (ar) 2016-09-26 2019-03-24 Merck Sharp & Dohme أجسام مضادة ضد cd27
TWI814525B (zh) 2017-02-14 2023-09-01 美商凱特製藥公司 Ｃｄ７０結合分子及使用彼之方法
GB201800649D0 (en) 2018-01-16 2018-02-28 Argenx Bvba CD70 Combination Therapy
PE20210708A1 (es) 2018-02-01 2021-04-16 Pfizer Anticuerpos especificos para cd70 y sus usos
JP2020019723A (ja) * 2018-07-30 2020-02-06 国立大学法人 鹿児島大学 抗ＣＤ７０抗体とＩｇＧ結合ペプチドの複合体
TWI848030B (zh) 2018-12-18 2024-07-11 比利時商阿根思公司 Ｃｄ７０組合治療
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