BR112014001613A2 - inibidor de tirosinase produzido com o uso de pó de minhoca seco e método para produzir o mesmo - Google Patents

inibidor de tirosinase produzido com o uso de pó de minhoca seco e método para produzir o mesmo

Info

Publication number
BR112014001613A2
BR112014001613A2 BR112014001613A BR112014001613A BR112014001613A2 BR 112014001613 A2 BR112014001613 A2 BR 112014001613A2 BR 112014001613 A BR112014001613 A BR 112014001613A BR 112014001613 A BR112014001613 A BR 112014001613A BR 112014001613 A2 BR112014001613 A2 BR 112014001613A2
Authority
BR
Brazil
Prior art keywords
tyrosinase
tyrosinase inhibitor
earthworm
same
produce
Prior art date
Application number
BR112014001613A
Other languages
English (en)
Other versions
BR112014001613B1 (pt
Inventor
Kazuyuki Ishii
Yoichi Ishii
Original Assignee
Well Stone Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Well Stone Co filed Critical Well Stone Co
Publication of BR112014001613A2 publication Critical patent/BR112014001613A2/pt
Publication of BR112014001613B1 publication Critical patent/BR112014001613B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0216—Solid or semisolid forms
    • A61K8/022—Powders; Compacted Powders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

resumo “inibidor de tirosinase produzido com o uso de pó de minhoca seco e método para produzir o mesmo” ou mais precisamente a presente invenção fornece um inibidor de tirosinase altamente seguro que tem excelente ação de inibição de tirosinase e um método para produzir o inibidor de tirosinase, que compreende as etapas de colocar em contato uma minhoca viva com pó de ácido hidroxicarboxílico, diluir a mistura resultante com água para ajustar o ph para 2 a 5 e, então, deixar a diluição resultante permanecer por 3 a 180 minutos ou colocar em contato uma minhoca viva com uma solução aquosa de ácido hidroxicarboxílico que tem um ph de 2 a 5 e, então, deixar a mistura resultante permanecer por 3 a 180 minutos; em seguida, lavar a minhoca viva com água, trituração da minhoca lavada e, então, secagem por congelamento do produto triturado obtido.
BR112014001613-5A 2011-07-29 2012-07-24 inibidor de tirosinase produzido com o uso de pó de minhoca seco e método para produzir o mesmo BR112014001613B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2011-167720 2011-07-29
JP2011167720 2011-07-29
PCT/JP2012/068718 WO2013018587A1 (ja) 2011-07-29 2012-07-24 ミミズ乾燥粉末を用いたチロシナーゼ阻害剤およびその製造方法

Publications (2)

Publication Number Publication Date
BR112014001613A2 true BR112014001613A2 (pt) 2017-01-10
BR112014001613B1 BR112014001613B1 (pt) 2019-01-22

Family

ID=47629114

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014001613-5A BR112014001613B1 (pt) 2011-07-29 2012-07-24 inibidor de tirosinase produzido com o uso de pó de minhoca seco e método para produzir o mesmo

Country Status (13)

Country Link
US (1) US9060958B2 (pt)
EP (1) EP2737893B1 (pt)
JP (1) JP5243662B1 (pt)
KR (1) KR101325004B1 (pt)
CN (1) CN103702661B (pt)
AU (1) AU2012291228B2 (pt)
BR (1) BR112014001613B1 (pt)
CA (1) CA2842891C (pt)
HK (1) HK1196277A1 (pt)
IL (1) IL230617B (pt)
RU (1) RU2576812C2 (pt)
TW (1) TWI542367B (pt)
WO (1) WO2013018587A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6321521B2 (ja) * 2014-11-04 2018-05-09 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 タウ蛋白産生促進剤、タウ蛋白の欠乏に起因する疾患の治療薬・予防薬および治療用・予防用食品組成物
JP2017025019A (ja) * 2015-07-21 2017-02-02 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 アミロイドβ線維分解剤、アミロイドβの線維化に起因する疾患の治療薬・予防薬および治療用・予防用食品組成物
US11260022B2 (en) 2017-03-21 2022-03-01 Well Stone Co. Method for producing oral composition, and oral composition
JP6249581B1 (ja) * 2017-06-12 2017-12-20 ワキ製薬株式会社 糖質分解酵素阻害剤の製造方法
TW201914575A (zh) * 2017-09-19 2019-04-16 大江生醫股份有限公司 地龍蛋白用於製造調理皮膚醫藥組成物之用途
CN108478488A (zh) * 2018-05-16 2018-09-04 冯敬洲 一种痘印修复液及其制备方法
CN109270057B (zh) * 2018-10-17 2021-07-20 无限极（中国）有限公司 一种检测美白化妆品功效的试剂盒及其制备方法和应用
CN114152688B (zh) * 2021-11-23 2023-07-04 华中农业大学 从蜂花粉提取物中筛选出特征标志物的方法及其应用

Family Cites Families (18)

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Publication number Priority date Publication date Assignee Title
US4568545A (en) * 1982-10-02 1986-02-04 Amano Seiyaku Kabushiki Kaisha Thrombolytic agent
JPS63238009A (ja) * 1987-03-25 1988-10-04 Ichimaru Pharcos Co Ltd ミミズ抽出物含有化粧料
US5024844A (en) * 1987-08-18 1991-06-18 Eimei Company, Ltd. Process for the production of dried earthworm powder and antihyperlipemic, antidiabetic, antihypertensive and antihypotensive preparations containing dried earthworm powder as active ingredient
JPH0290412A (ja) 1988-09-28 1990-03-29 Fujikura Ltd 電気ケーブル
US5186944A (en) * 1989-02-15 1993-02-16 Eimei Company Ltd. Therapeutic medicament for thrombosis
US5576026A (en) * 1994-09-30 1996-11-19 Charter; Edward A. Lumbricus product and method of making same
CN1281743C (zh) 2004-02-20 2006-10-25 北京百奥药业有限责任公司 蚓激酶干粉的制备方法
JP5123470B2 (ja) * 2005-08-05 2013-01-23 株式会社 皇漢薬品研究所 自動クロマトグラフ装置によるルムブロキナーゼ含有蛋白の製造方法と用途
CN101095697A (zh) * 2006-06-28 2008-01-02 李振国 水蛭和/或地龙分子量5800道尔顿以下的提取物
US8137701B2 (en) * 2008-03-21 2012-03-20 Well Stone Co. Method of producing a dry earthworm powder
ATE475425T1 (de) * 2008-03-26 2010-08-15 Well Stone Co Verfahren zur herstellung eines trockenen regenwurmpulvers
JP2009249362A (ja) * 2008-04-09 2009-10-29 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 無害化されたミミズ乾燥粉末の製造方法
US8337902B2 (en) * 2008-09-25 2012-12-25 Wisconsin Alumni Research Foundation Degradation of prion protein and reduced prion infectivity by earthworm homogenates
KR101682259B1 (ko) 2008-12-22 2016-12-05 포라 가세이 고교 가부시키가이샤 멜라닌 생산 억제제
JP4975069B2 (ja) 2009-07-29 2012-07-11 株式会社山田養蜂場本社 チロシナーゼ阻害剤
JP2011037764A (ja) 2009-08-11 2011-02-24 Shiseido Co Ltd 皮膚外用剤、美白剤、抗酸化剤および抗老化剤
JP4886017B2 (ja) * 2009-10-13 2012-02-29 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 ミミズ乾燥粉末の製造方法
JP4808822B1 (ja) 2011-04-11 2011-11-02 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 ミミズ乾燥粉末の製造方法

Also Published As

Publication number Publication date
US9060958B2 (en) 2015-06-23
TW201311292A (zh) 2013-03-16
CA2842891C (en) 2016-05-24
EP2737893A4 (en) 2015-04-29
IL230617A0 (en) 2014-03-31
KR101325004B1 (ko) 2013-11-04
WO2013018587A1 (ja) 2013-02-07
IL230617B (en) 2018-01-31
CN103702661A (zh) 2014-04-02
JPWO2013018587A1 (ja) 2015-03-05
RU2576812C2 (ru) 2016-03-10
AU2012291228B2 (en) 2016-07-28
BR112014001613B1 (pt) 2019-01-22
US20140154331A1 (en) 2014-06-05
CN103702661B (zh) 2015-10-07
AU2012291228A1 (en) 2014-03-13
EP2737893A1 (en) 2014-06-04
EP2737893B1 (en) 2017-08-30
TWI542367B (zh) 2016-07-21
JP5243662B1 (ja) 2013-07-24
KR20130058042A (ko) 2013-06-03
HK1196277A1 (en) 2014-12-12
RU2014107467A (ru) 2015-09-10
CA2842891A1 (en) 2013-02-07

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07B Technical examination (opinion): publication cancelled [chapter 7.2 patent gazette]
B15K Others concerning applications: alteration of classification

Ipc: A61K 35/62 (2006.01), A61K 8/02 (2006.01), A61K 8/

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 24/07/2012, OBSERVADAS AS CONDICOES LEGAIS.