BR112014000613A2 - método para a preparação de ácido ciclo-hexanocarboxílico - Google Patents

método para a preparação de ácido ciclo-hexanocarboxílico

Info

Publication number
BR112014000613A2
BR112014000613A2 BR112014000613A BR112014000613A BR112014000613A2 BR 112014000613 A2 BR112014000613 A2 BR 112014000613A2 BR 112014000613 A BR112014000613 A BR 112014000613A BR 112014000613 A BR112014000613 A BR 112014000613A BR 112014000613 A2 BR112014000613 A2 BR 112014000613A2
Authority
BR
Brazil
Prior art keywords
preparation
cyclohexanecarboxylic acid
useful
compound
formula
Prior art date
Application number
BR112014000613A
Other languages
English (en)
Inventor
Staempfli Andreas
Zogg Andreas
Walsh Andrew
Birrer Beat
Lautz Christian
Walch Christian
Smith Dennis
Veits Joachim
Pintao Joaquim
Hayes John
Schaefer Juergen
Jeisy Julius
Clarke Leo
Meade Michael
Scalone Michelangelo
E Martin Rainer
Deichtmann Walter
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BR112014000613A2 publication Critical patent/BR112014000613A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/02—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols
    • C07C319/06—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols from sulfides, hydropolysulfides or polysulfides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/22—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/20—Esters of monothiocarboxylic acids
    • C07C327/30—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/02—Preparation of carboxylic acids or their salts, halides or anhydrides from salts of carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/06—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/08—Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/58—Preparation of carboxylic acid halides
    • C07C51/60—Preparation of carboxylic acid halides by conversion of carboxylic acids or their anhydrides or esters, lactones, salts into halides with the same carboxylic acid part
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Abstract

resumo método para a preparação de ácido ciclo-hexanocarboxílico expõe-se um processo para a preparação de um composto da fórmula (i): (i), oho o qual é útil como intermediário para a 5 preparação de compostos farmaceuticamente ativos i.a..
BR112014000613A 2011-07-13 2012-07-10 método para a preparação de ácido ciclo-hexanocarboxílico BR112014000613A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11173736 2011-07-13
PCT/EP2012/063455 WO2013007712A1 (en) 2011-07-13 2012-07-10 Method for the preparation of cyclohexanecarboxylic acid

Publications (1)

Publication Number Publication Date
BR112014000613A2 true BR112014000613A2 (pt) 2017-02-14

Family

ID=46508343

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014000613A BR112014000613A2 (pt) 2011-07-13 2012-07-10 método para a preparação de ácido ciclo-hexanocarboxílico

Country Status (11)

Country Link
US (1) US8975438B2 (pt)
EP (1) EP2731930A1 (pt)
JP (2) JP2014522853A (pt)
KR (1) KR20140039045A (pt)
CN (2) CN107011148A (pt)
AR (1) AR087118A1 (pt)
BR (1) BR112014000613A2 (pt)
CA (1) CA2839638A1 (pt)
MX (1) MX2014000304A (pt)
RU (1) RU2014102445A (pt)
WO (1) WO2013007712A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2978859T (pt) 2013-03-27 2018-10-04 Hoffmann La Roche Marcadores genéticos para previsão da capacidade de resposta à terapêutica
MX2017000582A (es) 2014-07-30 2017-04-27 Hoffmann La Roche Marcadores geneticos para predecir la reactividad a terapia con agente que eleva la lipoproteina de alta densidad (hdl) o que imita la lipoproteina de alta densidad (hdl).

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4485117A (en) 1981-10-16 1984-11-27 Hudson Alan T Antiprotozoal compounds
US5763652A (en) * 1995-03-08 1998-06-09 Daicel Chemical Industries, Ltd. Process for producing a carboxylic acid
JP2894445B2 (ja) 1997-02-12 1999-05-24 日本たばこ産業株式会社 Ｃｅｔｐ活性阻害剤として有効な化合物
JPH11147850A (ja) * 1997-11-14 1999-06-02 Sumika Fine Chemicals Co Ltd ビフェニルカルボン酸類の製造方法
DK1115683T3 (da) * 1998-09-26 2004-03-08 Aventis Pharma Gmbh Fremgangsmåde til trykfri fremstilling af alpha,alpha-dimethylphenyleddikesyre ud fra alpha,alpha-dimethylbenzylcyanid
JP4546798B2 (ja) * 2004-09-30 2010-09-15 本州化学工業株式会社 エキソ型架橋脂環式モノオレフィンカルボン酸の製造方法
CN100338008C (zh) * 2005-04-20 2007-09-19 江苏省原子医学研究所 1－羧基－1－(3,5－二甲氧基苯基)－2－(4－r基苯基)乙烯及其制备方法
US7435849B2 (en) 2005-10-31 2008-10-14 Hoffmann-La Roche Inc. Process for the production of acid chlorides
BRPI0909813B1 (pt) * 2008-04-04 2018-01-02 F. Hoffmann-La Roche Ag "processos para preparação de derivados de ácido ciclo-hexanocarboxílico, e intermediário"
KR101290935B1 (ko) * 2008-04-04 2013-07-29 에프. 호프만-라 로슈 아게 상응하는 사이클로헥세인카복스아마이드 유도체에 의한 사이클로헥세인카복실산 유도체의 신규한 제조 방법
CN102066311B (zh) 2008-06-17 2014-07-02 弗·哈夫曼-拉罗切有限公司 用作药物活性酰胺制备中的中间体的1-(2-乙基丁基)-环己烷羧酸酯
CN101565369B (zh) * 2009-05-22 2012-10-03 江苏开元医药化工有限公司 一种3-溴-5-三氟甲基苯甲酸的制备方法
US20110004011A1 (en) 2009-07-01 2011-01-06 Declan Costello Novel process
PT2462098E (pt) * 2009-08-04 2013-12-04 Chiesi Farma Spa Processos para a preparação de derivados de ácido 1-(2- halobifenil-4-il)-ciclopropanocarboxílico

Also Published As

Publication number Publication date
EP2731930A1 (en) 2014-05-21
MX2014000304A (es) 2014-02-20
AR087118A1 (es) 2014-02-12
CN107011148A (zh) 2017-08-04
RU2014102445A (ru) 2015-08-20
CN103649046A (zh) 2014-03-19
WO2013007712A1 (en) 2013-01-17
US20130018201A1 (en) 2013-01-17
US8975438B2 (en) 2015-03-10
KR20140039045A (ko) 2014-03-31
JP2017095506A (ja) 2017-06-01
CA2839638A1 (en) 2013-01-17
JP2014522853A (ja) 2014-09-08

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2522 DE 07-05-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.