BR112013032273A2 - derivados de 1,3-dioxoindeno, sal farmaceuticamente aceitável dos mesmos, método de preparação dos mesmos e composição farmacêutica para o antivírus contendo a mesma como um ingrediente ativo - Google Patents
derivados de 1,3-dioxoindeno, sal farmaceuticamente aceitável dos mesmos, método de preparação dos mesmos e composição farmacêutica para o antivírus contendo a mesma como um ingrediente ativoInfo
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- BR112013032273A2 BR112013032273A2 BR112013032273A BR112013032273A BR112013032273A2 BR 112013032273 A2 BR112013032273 A2 BR 112013032273A2 BR 112013032273 A BR112013032273 A BR 112013032273A BR 112013032273 A BR112013032273 A BR 112013032273A BR 112013032273 A2 BR112013032273 A2 BR 112013032273A2
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- pharmaceutical composition
- active ingredient
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- dioxoindene derivatives
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Abstract
resumo patente de invenção: "derivados de 1,3-dioxoindeno, sal farmaceuticamente aceitável dos mesmos, método de preparação dos mesmos e composição farmacêutica para o antivírus contendo a mesma como um ingrediente ativo". a presente invenção refere-se a derivados de 1,3-dioxoindeno, sais farmaceuticamente aceitáveis ou isômeros, um método de preparação para os mesmos, e uma composição farmacêutica para prevenção ou tratamento de doenças virais,compreendendo os mesmos como um ingrediente ativo. os derivados de 1,3-dioxoindeno tem excelente atividade inibitória contra picornavírus incluindo coxsackie-, entero-, eco-, polio-, e os rinovírus, assim como, exibindo baixa citotoxidade, de um modo que eles podem ser úteis como um ingrediente ativo de uma composição farmacêuticapara a prevenção ou tratamento de doenças virais incluindo poliomelite, paralisia viral, conjuntivite hemorrágica aguda, meningite viral, doença mão-pé-boca, doenças vesiculares, hepatite a, miosite, miocardite, pancreatite, diabetes, mialgia epidêmica, encefalite, resfriado, herpangina, doença de pé-e-boca, asma, doença pulmonar obstrutiva crônica, pneumonia, sinusite, otite média.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20110058704 | 2011-06-16 | ||
KR10-2011-0058704 | 2011-06-16 | ||
KR1020120065023A KR101391745B1 (ko) | 2011-06-16 | 2012-06-18 | 1,3-다이옥소인덴 유도체, 이의 약학적으로 허용되는 염 또는 이의 광학 이성질체, 이의 제조방법 및 이를 유효성분으로 함유하는 항바이러스용 약학적 조성물 |
KR10-2012-0065023 | 2012-06-18 | ||
PCT/KR2012/004804 WO2012173447A2 (ko) | 2011-06-16 | 2012-06-18 | 1,3-다이옥소인덴 유도체, 이의 약학적으로 허용되는 염 또는 이의 광학 이성질체, 이의 제조방법 및 이를 유효성분으로 함유하는 항바이러스용 약학적 조성물 |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112013032273A2 true BR112013032273A2 (pt) | 2016-12-20 |
BR112013032273B1 BR112013032273B1 (pt) | 2020-11-17 |
Family
ID=47357637
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112013032273-0A BR112013032273B1 (pt) | 2011-06-16 | 2012-06-18 | Compostos derivados de 1,3-dioxoindeno, seus usos, métodos de preparação dos mesmos e composições farmacêutica |
Country Status (16)
Country | Link |
---|---|
US (2) | US9346749B2 (pt) |
EP (3) | EP3611158B1 (pt) |
JP (2) | JP5941142B2 (pt) |
KR (1) | KR101391745B1 (pt) |
CN (1) | CN103748060B (pt) |
AU (1) | AU2012270310B2 (pt) |
BR (1) | BR112013032273B1 (pt) |
CA (1) | CA2838680C (pt) |
EA (1) | EA025384B1 (pt) |
ES (1) | ES2744982T3 (pt) |
MX (1) | MX355498B (pt) |
PL (1) | PL2722322T3 (pt) |
PT (1) | PT2722322T (pt) |
RU (1) | RU2566761C2 (pt) |
SI (1) | SI2722322T1 (pt) |
WO (1) | WO2012173447A2 (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2933254B1 (en) * | 2012-12-14 | 2021-01-20 | Korea Research Institute of Chemical Technology | Novel compound, pharmaceutically acceptable salt or optical isomer thereof, method for preparing same, and pharmaceutical composition for prevention or treatment of viral diseases containing same as active ingredient |
CN104557559B (zh) * | 2015-01-14 | 2016-08-17 | 成都中医药大学 | 茚满二酮手性环己烷螺环化合物及其制备方法与用途 |
KR102067858B1 (ko) | 2016-05-24 | 2020-01-17 | 주식회사 엘지화학 | 화합물 및 이를 포함하는 색재 조성물 및 이를 포함하는 수지 조성물 |
TWI832045B (zh) * | 2020-04-20 | 2024-02-11 | 瑞士商諾華公司 | 抗病毒性1,3-二氧代茚化合物 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1425295A (en) * | 1974-01-23 | 1976-02-18 | Rizh Politekhn I | Alpha-aminoylidenephthalides and processes for their preparation |
FR2392951A2 (fr) | 1975-02-07 | 1978-12-29 | Creat Lab | Nouveaux derives de la ninhydrine, leurs procedes de preparation et medicaments contenant ces derives |
GB1533388A (en) | 1975-02-07 | 1978-11-22 | Creat | Ninhydrin-phenol condensation products their preparation and use as therapeutic agents |
GB8327598D0 (en) * | 1983-10-14 | 1983-11-16 | Akzo Nv | Pharmacologically active diarylindane-13-diones |
CO4950519A1 (es) | 1997-02-13 | 2000-09-01 | Novartis Ag | Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion |
JP2001089455A (ja) | 1999-09-17 | 2001-04-03 | Maruishi Pharmaceutical Co Ltd | 5,10−ジヒドロ−11H−インデノ〔1,2−b〕キノリン−10−オン誘導体 |
ATE277017T1 (de) * | 1999-08-30 | 2004-10-15 | Maruishi Pharma | 1,2-disubstituierte 1,4-dihydro-4-oxochinolin- verbindungen |
WO2003082265A2 (en) * | 2002-04-02 | 2003-10-09 | Fujisawa Pharmaceutical Co | Pharmaceutical composition for treating or preventing virus infectious diseases |
CA2520124A1 (en) | 2003-03-28 | 2004-10-14 | Chiron Corporation | Use of benzazole compounds for immunopotentiation |
WO2008018833A1 (en) * | 2006-08-08 | 2008-02-14 | Agency For Science, Technology And Research | Methods for electrochemical detection/quantification of a nucleic acid |
JP2011526925A (ja) * | 2008-07-01 | 2011-10-20 | ザカロン ファーマシューティカルズ,インク. | ヘパラン硫酸阻害剤 |
EP2324820B1 (en) | 2009-11-04 | 2016-03-02 | Inopharm Limited | Stable fluindione composition comprising one or more antioxidant agents |
-
2012
- 2012-06-18 US US14/126,479 patent/US9346749B2/en active Active
- 2012-06-18 EP EP19179546.7A patent/EP3611158B1/en active Active
- 2012-06-18 CA CA2838680A patent/CA2838680C/en active Active
- 2012-06-18 JP JP2014515763A patent/JP5941142B2/ja active Active
- 2012-06-18 EP EP23218086.9A patent/EP4360710A3/en active Pending
- 2012-06-18 EA EA201490025A patent/EA025384B1/ru not_active IP Right Cessation
- 2012-06-18 WO PCT/KR2012/004804 patent/WO2012173447A2/ko active Application Filing
- 2012-06-18 BR BR112013032273-0A patent/BR112013032273B1/pt active IP Right Grant
- 2012-06-18 PL PL12799827T patent/PL2722322T3/pl unknown
- 2012-06-18 SI SI201231664T patent/SI2722322T1/sl unknown
- 2012-06-18 AU AU2012270310A patent/AU2012270310B2/en active Active
- 2012-06-18 ES ES12799827T patent/ES2744982T3/es active Active
- 2012-06-18 RU RU2014101179/04A patent/RU2566761C2/ru active
- 2012-06-18 CN CN201280029665.4A patent/CN103748060B/zh active Active
- 2012-06-18 KR KR1020120065023A patent/KR101391745B1/ko active IP Right Grant
- 2012-06-18 PT PT12799827T patent/PT2722322T/pt unknown
- 2012-06-18 MX MX2013014239A patent/MX355498B/es active IP Right Grant
- 2012-06-18 EP EP12799827.6A patent/EP2722322B8/en active Active
-
2016
- 2016-04-14 US US15/098,972 patent/US9833423B2/en active Active
- 2016-05-18 JP JP2016099511A patent/JP6373297B2/ja active Active
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B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
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Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 18/06/2012, OBSERVADAS AS CONDICOES LEGAIS. |