PT2722322T - Derivado de 1,3-di-oxo-indeno, seu sal farmaceuticamente aceitável ou isómero ótico, seu método de preparação, e composição farmacêutica contendo o mesmo como ingrediente ativo, antiviral - Google Patents

Derivado de 1,3-di-oxo-indeno, seu sal farmaceuticamente aceitável ou isómero ótico, seu método de preparação, e composição farmacêutica contendo o mesmo como ingrediente ativo, antiviral

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Publication number
PT2722322T
PT2722322T PT12799827T PT12799827T PT2722322T PT 2722322 T PT2722322 T PT 2722322T PT 12799827 T PT12799827 T PT 12799827T PT 12799827 T PT12799827 T PT 12799827T PT 2722322 T PT2722322 T PT 2722322T
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Portugal
Prior art keywords
antiviral
oxo
preparation
pharmaceutically acceptable
pharmaceutical composition
Prior art date
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PT12799827T
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English (en)
Inventor
Neyts Johan
Sik Jung Young
Kgo Lee Chong
Young Choi Ihl
Soo Kim Hae
Ho Kim Pil
Bong Han Soo
Jan Thibaut Hendrik
Original Assignee
Katholieke Univ Leuven K U Leuven R&D
Korea Res Inst Chemical Tech
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Application filed by Katholieke Univ Leuven K U Leuven R&D, Korea Res Inst Chemical Tech filed Critical Katholieke Univ Leuven K U Leuven R&D
Publication of PT2722322T publication Critical patent/PT2722322T/pt

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    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734—Ethers
    • C07C69/736—Ethers the hydroxy group of the ester being etherified with a hydroxy compound having the hydroxy group bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
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    • C07—ORGANIC CHEMISTRY
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    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
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    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
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    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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PT12799827T 2011-06-16 2012-06-18 Derivado de 1,3-di-oxo-indeno, seu sal farmaceuticamente aceitável ou isómero ótico, seu método de preparação, e composição farmacêutica contendo o mesmo como ingrediente ativo, antiviral PT2722322T (pt)

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CN104557559B (zh) * 2015-01-14 2016-08-17 成都中医药大学 茚满二酮手性环己烷螺环化合物及其制备方法与用途
KR102067858B1 (ko) 2016-05-24 2020-01-17 주식회사 엘지화학 화합물 및 이를 포함하는 색재 조성물 및 이를 포함하는 수지 조성물
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CO4950519A1 (es) * 1997-02-13 2000-09-01 Novartis Ag Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion
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US7893096B2 (en) 2003-03-28 2011-02-22 Novartis Vaccines And Diagnostics, Inc. Use of small molecule compounds for immunopotentiation
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EA201490025A1 (ru) 2014-05-30
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JP6373297B2 (ja) 2018-08-15
CA2838680C (en) 2018-01-02
EP3611158B1 (en) 2023-12-20
SI2722322T1 (sl) 2019-11-29
EP2722322B8 (en) 2020-03-11
MX355498B (es) 2018-04-20
JP2014523416A (ja) 2014-09-11
EP4360710A2 (en) 2024-05-01
AU2012270310A8 (en) 2014-01-23
CN103748060B (zh) 2016-04-13
BR112013032273A2 (pt) 2016-12-20
EP2722322A4 (en) 2014-12-17
WO2012173447A3 (ko) 2013-04-04
US9833423B2 (en) 2017-12-05
US20140121187A1 (en) 2014-05-01
JP5941142B2 (ja) 2016-06-29
PL2722322T3 (pl) 2020-02-28
WO2012173447A2 (ko) 2012-12-20
EP2722322B1 (en) 2019-06-12
AU2012270310A1 (en) 2012-12-20
MX2013014239A (es) 2014-05-14
AU2012270310B2 (en) 2016-01-28
EA025384B1 (ru) 2016-12-30
RU2566761C2 (ru) 2015-10-27
KR20120139606A (ko) 2012-12-27
US9346749B2 (en) 2016-05-24
US20160272564A1 (en) 2016-09-22
ES2744982T3 (es) 2020-02-27
EP3611158A1 (en) 2020-02-19
CN103748060A (zh) 2014-04-23
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RU2014101179A (ru) 2015-07-27
CA2838680A1 (en) 2012-12-20

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