BR112013031810A2 - valenceno sintase, ácido nucleico, vetor de expressão, anticorpo, célula hospedeira e métodos para preparar valenceno e nootkatona - Google Patents

valenceno sintase, ácido nucleico, vetor de expressão, anticorpo, célula hospedeira e métodos para preparar valenceno e nootkatona

Info

Publication number
BR112013031810A2
BR112013031810A2 BR112013031810A BR112013031810A BR112013031810A2 BR 112013031810 A2 BR112013031810 A2 BR 112013031810A2 BR 112013031810 A BR112013031810 A BR 112013031810A BR 112013031810 A BR112013031810 A BR 112013031810A BR 112013031810 A2 BR112013031810 A2 BR 112013031810A2
Authority
BR
Brazil
Prior art keywords
valencene
nootkatone
antibody
nucleic acid
methods
Prior art date
Application number
BR112013031810A
Other languages
English (en)
Inventor
M De Jong Rene
Sonke Theodorus
Original Assignee
Isobionics B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isobionics B V filed Critical Isobionics B V
Publication of BR112013031810A2 publication Critical patent/BR112013031810A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03073—Valencene synthase (4.2.3.73)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
BR112013031810A 2011-06-21 2012-06-21 valenceno sintase, ácido nucleico, vetor de expressão, anticorpo, célula hospedeira e métodos para preparar valenceno e nootkatona BR112013031810A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11170805A EP2537926A1 (en) 2011-06-21 2011-06-21 Valencene synthase
PCT/NL2012/050434 WO2012177129A2 (en) 2011-06-21 2012-06-21 Valencene synthase

Publications (1)

Publication Number Publication Date
BR112013031810A2 true BR112013031810A2 (pt) 2017-07-11

Family

ID=44855758

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013031810A BR112013031810A2 (pt) 2011-06-21 2012-06-21 valenceno sintase, ácido nucleico, vetor de expressão, anticorpo, célula hospedeira e métodos para preparar valenceno e nootkatona

Country Status (6)

Country Link
US (2) US20150079649A1 (pt)
EP (2) EP2537926A1 (pt)
JP (1) JP2014519841A (pt)
CN (1) CN103649309A (pt)
BR (1) BR112013031810A2 (pt)
WO (1) WO2012177129A2 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150259705A1 (en) * 2012-07-18 2015-09-17 Isobionics B.V. Rhodobacter for preparing terpenoids
PL2970934T3 (pl) 2013-03-14 2018-01-31 Evolva Inc Polipeptydy syntazy walencenu, kodujące cząsteczki kwasu nukleinowego oraz ich zastosowania
EP3432709A1 (en) 2016-03-24 2019-01-30 Evolva SA Use of nootkatone to kill sap-sucking insects
WO2017162883A1 (en) 2016-03-24 2017-09-28 Evolva Sa Methods and compositions for the prevention of infections and arthropod infestation
WO2018015453A2 (en) * 2016-07-20 2018-01-25 Firmenich Sa Vetiver
WO2018043546A1 (ja) * 2016-08-30 2018-03-08 三菱ケミカル株式会社 変異型酵素の製造方法及び変異型アルコールアシルトランスフェラーゼ
US11154057B2 (en) 2016-09-02 2021-10-26 Evolva Sa Use of nootkatone to treat mosquito infestations
CN107723252A (zh) * 2017-09-22 2018-02-23 天津大学 生产巴伦西亚橘烯和诺卡酮的重组解脂耶氏酵母菌及构建方法
CN111154665B (zh) * 2020-01-21 2021-02-02 南京工业大学 一株重组解脂耶罗维亚酵母及其构建方法和应用
CN116463325A (zh) * 2022-01-11 2023-07-21 武汉合生科技有限公司 瓦伦烯合酶突变体及瓦伦烯高产菌株

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8300698A (nl) 1983-02-24 1984-09-17 Univ Leiden Werkwijze voor het inbouwen van vreemd dna in het genoom van tweezaadlobbige planten; agrobacterium tumefaciens bacterien en werkwijze voor het produceren daarvan; planten en plantecellen met gewijzigde genetische eigenschappen; werkwijze voor het bereiden van chemische en/of farmaceutische produkten.
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US5015580A (en) 1987-07-29 1991-05-14 Agracetus Particle-mediated transformation of soybean plants and lines
US5350689A (en) 1987-05-20 1994-09-27 Ciba-Geigy Corporation Zea mays plants and transgenic Zea mays plants regenerated from protoplasts or protoplast-derived cells
ES2121803T3 (es) 1987-05-20 1998-12-16 Novartis Ag Plantas de zea mays y plantas transgenicas de zea mays generadas a partir de protoplastos o celulas derivadas de protoplastos.
NZ225044A (en) 1987-06-19 1990-01-29 Plant Cell Res Inst Bertholletia excelsa dna molecule; sulphur rich storage protein
ES2097746T3 (es) 1988-03-08 1997-04-16 Ciba Geigy Ag Regeneracion de plantas gramineas de la subfamilia pooideae partiendo de protoplastos.
US5451513A (en) 1990-05-01 1995-09-19 The State University of New Jersey Rutgers Method for stably transforming plastids of multicellular plants
DE4207358A1 (de) 1992-03-04 1993-09-09 Inst Genbiologische Forschung Expressionskassette und plasmide zur schliesszellenspezifischen expression und ihre verwendung zur herstellung transgener pflanzenzellen und pflanzen
US5576198A (en) 1993-12-14 1996-11-19 Calgene, Inc. Controlled expression of transgenic constructs in plant plastids
US5545817A (en) 1994-03-11 1996-08-13 Calgene, Inc. Enhanced expression in a plant plastid
US5545818A (en) 1994-03-11 1996-08-13 Calgene Inc. Expression of Bacillus thuringiensis cry proteins in plant plastids
WO1996041882A1 (en) 1995-06-12 1996-12-27 Proefstation Voor De Champignoncultuur Hydrophobins from edible fungi, genes, nucleotide sequences and dna-fragments encoding for said hydrophobins, and expression thereof
JP3935940B2 (ja) 1995-12-18 2007-06-27 フイルメニツヒ ソシエテ アノニム ヌートカトンの製造法
DE19632293C2 (de) 1996-08-09 1999-06-10 Thomas Prof Dr In Steinhaeuser Verfahren zur Herstellung von Kernformlingen für die Gießereitechnik
DE19644478A1 (de) 1996-10-25 1998-04-30 Basf Ag Blattspezifische Expression von Genen in transgenen Pflanzen
CA2296989C (en) 1999-01-29 2005-10-25 Lucent Technologies Inc. A method and apparatus for managing a firewall
US6200786B1 (en) 1999-09-08 2001-03-13 Givaudan S.A. Process for the preparation of nootkatone by laccase catalysis
US7115733B2 (en) 2003-07-03 2006-10-03 Unicrop Ltd Rubisco promoters and uses thereof
EP1256629A1 (en) 2001-05-11 2002-11-13 Société des Produits Nestlé S.A. Leaf specifc gene promoter of coffee
JP4746224B2 (ja) 2001-09-04 2011-08-10 高砂香料工業株式会社 ヌートカトンの製造方法
CN1589327A (zh) * 2001-09-17 2005-03-02 植物研究国际公司 用于生物转化的植物酶
ES2607122T3 (es) 2002-10-04 2017-03-29 Firmenich Sa Sesquiterpeno sintasas y procedimientos de uso
EP1554379B1 (en) * 2002-10-04 2012-02-22 Firmenich SA Sesquiterpene synthases and methods of use
ATE426662T1 (de) 2003-06-12 2009-04-15 Dsm Ip Assets Bv Feedback resistante mevalonate kinase
EP1641931B1 (en) 2003-07-08 2008-11-19 DSM IP Assets B.V. Improved production of coenzyme q-10
US7442785B2 (en) 2003-07-24 2008-10-28 The University Of Kentucky Research Foundation Sesquiterpene synthase gene and protein
EP1659996A4 (en) * 2003-09-02 2008-07-02 Israel State CITRUS SESQUITERPEN SYNTHASE, MANUFACTURING AND USE METHOD THEREFOR
CN101044243B (zh) 2004-08-19 2011-12-28 帝斯曼知识产权资产管理有限公司 类异戊二烯的生产方法
JP4841562B2 (ja) 2004-12-14 2011-12-21 ディーエスエム アイピー アセッツ ビー．ブイ． 改良型メバロネートキナーゼ
WO2006079020A2 (en) 2005-01-19 2006-07-27 University Of Kentucky Research Foundation Functional identification of the hyoscyamus muticus gene coding for premnaspirodiene hydroxylase activity
DK1861504T3 (da) 2005-03-07 2010-04-26 Stichting Dienst Landbouwkundi Glycoengineering i svampe
CN101384719B (zh) 2006-02-14 2012-10-03 弗门尼舍有限公司 用于生成萜的方法和用于该方法的mep转化后的微生物
ES2534282T3 (es) 2006-06-29 2015-04-21 Dsm Ip Assets B.V. Un método para lograr la expresión polipeptídica mejorada
MX302107B (es) 2007-09-20 2012-08-08 Amyris Biotechnologies Inc Produccion de isoprenoides.
EP2336310A1 (en) * 2009-12-16 2011-06-22 Isobionics B.V. Valencene synthase

Also Published As

Publication number Publication date
EP2537926A1 (en) 2012-12-26
EP2780452A2 (en) 2014-09-24
WO2012177129A2 (en) 2012-12-27
JP2014519841A (ja) 2014-08-21
US20150079649A1 (en) 2015-03-19
EP2780452B1 (en) 2016-12-28
WO2012177129A3 (en) 2013-02-28
CN103649309A (zh) 2014-03-19
US20190136221A1 (en) 2019-05-09

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