EP1659996A4 - Citrus sesquiterpene synthase, methods of production and uses thereof - Google Patents

Citrus sesquiterpene synthase, methods of production and uses thereof

Info

Publication number
EP1659996A4
EP1659996A4 EP04770466A EP04770466A EP1659996A4 EP 1659996 A4 EP1659996 A4 EP 1659996A4 EP 04770466 A EP04770466 A EP 04770466A EP 04770466 A EP04770466 A EP 04770466A EP 1659996 A4 EP1659996 A4 EP 1659996A4
Authority
EP
European Patent Office
Prior art keywords
production
methods
sesquiterpene synthase
citrus
citrus sesquiterpene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP04770466A
Other languages
German (de)
French (fr)
Other versions
EP1659996A2 (en
Inventor
Yoram Eyal
Efraim Lewinsohn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
State of Israel
Original Assignee
State of Israel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by State of Israel filed Critical State of Israel
Publication of EP1659996A2 publication Critical patent/EP1659996A2/en
Publication of EP1659996A4 publication Critical patent/EP1659996A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Nutrition Science (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cosmetics (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
EP04770466A 2003-09-02 2004-09-02 Citrus sesquiterpene synthase, methods of production and uses thereof Withdrawn EP1659996A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49902403P 2003-09-02 2003-09-02
PCT/IL2004/000795 WO2005021705A2 (en) 2003-09-02 2004-09-02 Citrus sesquiterpene synthase, methods of production and uses thereof

Publications (2)

Publication Number Publication Date
EP1659996A2 EP1659996A2 (en) 2006-05-31
EP1659996A4 true EP1659996A4 (en) 2008-07-02

Family

ID=34272763

Family Applications (1)

Application Number Title Priority Date Filing Date
EP04770466A Withdrawn EP1659996A4 (en) 2003-09-02 2004-09-02 Citrus sesquiterpene synthase, methods of production and uses thereof

Country Status (5)

Country Link
EP (1) EP1659996A4 (en)
JP (1) JP2007517496A (en)
AU (1) AU2004269197A1 (en)
CA (1) CA2537505A1 (en)
WO (1) WO2005021705A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0314979B1 (en) 2002-10-04 2019-10-22 Firmenich & Cie Production method of a valenceno and transgenic microorganism
US7442785B2 (en) 2003-07-24 2008-10-28 The University Of Kentucky Research Foundation Sesquiterpene synthase gene and protein
US9297004B2 (en) 2008-03-06 2016-03-29 Firmenich Sa Method for producing α-santalene
JP5649020B2 (en) * 2008-10-10 2015-01-07 国立大学法人岩手大学 Repression of soybean endogenous gene expression by recombinant ALSV
CA2815829A1 (en) 2010-10-29 2012-05-03 Allylix, Inc. Modified valencene synthase polypeptides, encoding nucleic acid molecules and uses thereof
EP2537926A1 (en) * 2011-06-21 2012-12-26 Isobionics B.V. Valencene synthase
US20150250166A1 (en) 2012-08-23 2015-09-10 Allylix, Inc. Nootkatone as an insecticide and insect repellent
EP2970934B1 (en) 2013-03-14 2017-08-16 Evolva, Inc. Valencene synthase polypeptides, encoding nucleic acid molecules and uses thereof
ES2540791B1 (en) * 2013-12-13 2016-05-09 Consejo Superior De Investigaciones Científicas (Csic) New sesquiterpene synthases isolated from orange peel.
KR20200121331A (en) 2018-02-14 2020-10-23 징코 바이오웍스, 인크. Chimeric terpene synthase

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004031376A2 (en) * 2002-10-04 2004-04-15 Firmenich Sa Sesquiterpene synthases and methods of use
US20060218661A1 (en) * 2003-07-24 2006-09-28 Joe Chappell Novel sesquiterpene synthase gene and protein

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4970085A (en) 1989-10-19 1990-11-13 The Procter & Gamble Company Process for making improved citrus aqueous essence and product produced therefrom

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004031376A2 (en) * 2002-10-04 2004-04-15 Firmenich Sa Sesquiterpene synthases and methods of use
US20060218661A1 (en) * 2003-07-24 2006-09-28 Joe Chappell Novel sesquiterpene synthase gene and protein

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
BOHLMANN JORG ET AL: "Plant terpenoid synthases: Molecular biology and phylogenetic analysis", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, vol. 95, no. 8, 14 April 1998 (1998-04-14), pages 4126 - 4133, XP002171016, ISSN: 0027-8424 *
CHAPPELL JOE: "Valencene synthase - a biochemical magician and harbinger of transgenic aromas", TRENDS IN PLANT SCIENCE, vol. 9, no. 6, June 2004 (2004-06-01), pages 266 - 269, XP002480419, ISSN: 1360-1385 *
DATABASE EMBL [online] 3 April 2002 (2002-04-03), "Citrus x paradisi putative terpene synthase mRNA, complete cds.", XP002480420, retrieved from EBI accession no. EMBL:AF411120 Database accession no. AF411120 *
GREENHAGEN B T: "Origins Of Isoprenoid Diversity: A Study Of Structure-Function Relationsships In Sesquiterpene Synthases - Dissertation", 15 July 2003 (2003-07-15), XP002480418, Retrieved from the Internet <URL:http://lib.uky.edu/ETD/ukyplph2003d00093/Greenhagen.pdf> *
LUCKER J ET AL: "Vitis vinifera terpenoid cyclases: functional identification of two sesquiterpene synthase cDNAs encoding (+)-valencene synthase and (-)-germacrene D synthase and expression of mono- and sesquiterpene synthases in grapevine flowers and berries", PHYTOCHEMISTRY, PERGAMON PRESS, GB, vol. 65, no. 19, 1 October 2004 (2004-10-01), pages 2649 - 2659, XP004586632, ISSN: 0031-9422 *
See also references of WO2005021705A2 *
SHARON-ASA L ET AL: "Citrus fruit flavor and aroma biosynthesis: Isolation, functional characterization, and developmental regulation of Cstps1, a key gene in the production of the sesquiterpene aroma compound valencene", PLANT JOURNAL, BLACKWELL SCIENTIFIC PUBLICATIONS, OXFORD, GB, vol. 36, no. 5, 1 December 2003 (2003-12-01), pages 664 - 674, XP002282506, ISSN: 0960-7412 *

Also Published As

Publication number Publication date
AU2004269197A1 (en) 2005-03-10
CA2537505A1 (en) 2005-03-10
WO2005021705A2 (en) 2005-03-10
WO2005021705A9 (en) 2009-04-16
EP1659996A2 (en) 2006-05-31
WO2005021705A3 (en) 2005-04-21
JP2007517496A (en) 2007-07-05
WO2005021705A8 (en) 2005-12-22

Similar Documents

Publication Publication Date Title
EP1927587A3 (en) Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof
AU2003255106A1 (en) 5-enolpyruvyl-3-phosphoshikimate synthase of high glyphosate-bioresistance and coding sequence
AU2003903909A0 (en) Production methods
WO2005047505A3 (en) Methods and products for expression of micro rnas
IL173204A0 (en) Novel cyanopyrrolidides, methods for the production thereof, and use of the same as medicaments
TWI347958B (en) Aqueous dispersion, its production method, and its use
IL167832A (en) Sesquiterpene synthases and methods of use
IL190472A (en) Anti-glypican-3 antibodies, methods of producing same and uses thereof
EP1808497A4 (en) Isocyclomaltooligosaccharide, isocyclomaltooligosaccharide synthase, process for producing them and use thereof
EP1598374A4 (en) Method of producing polymer
EP1668125A4 (en) Modified enzymes, methods to produce modified enzymes and uses thereof
EP1602624A4 (en) Mems element and method of producing the same, and diffraction type mems element
AU2003261191A8 (en) Methods for producing biopolymers
EP1639096A4 (en) Methods of producing neurons
EP1674474A4 (en) Cyclic maltosyl maltose, cyclic maltosyl maltose synthase, method of producing the same and use thereof
EP1929883A4 (en) Soy sauce containing 5 -nucleotides and method of producing the same
EP1659996A4 (en) Citrus sesquiterpene synthase, methods of production and uses thereof
EP1627675A4 (en) Component separating device, method of producing the device, and method of separating component by using the device
EP1627046A4 (en) Domain-exchanged binding molecules, methods of use and methods of production
AU2003261327A8 (en) Base assemblies, methods of production and uses thereof
EP1750681A4 (en) Decontaminant edible product, methods of production and uses thereof
ZA200405862B (en) Method of changing very large tires.
AU2003261099A8 (en) 4,7-disubstituted indoles and methods of making
GB0302553D0 (en) Production of disc components
AU2003287844A1 (en) Novel crystalline forms of entacapone, and production thereof

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20060307

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL HR LT LV MK

DAX Request for extension of the european patent (deleted)
RIC1 Information provided on ipc code assigned before grant

Ipc: C12N 5/10 20060101ALI20080520BHEP

Ipc: C12N 9/88 20060101ALI20080520BHEP

Ipc: C12N 15/82 20060101AFI20080520BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20080530

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20080819