WO2005021705A3 - Citrus sesquiterpene synthase, methods of production and uses thereof - Google Patents

Citrus sesquiterpene synthase, methods of production and uses thereof Download PDF

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Publication number
WO2005021705A3
WO2005021705A3 PCT/IL2004/000795 IL2004000795W WO2005021705A3 WO 2005021705 A3 WO2005021705 A3 WO 2005021705A3 IL 2004000795 W IL2004000795 W IL 2004000795W WO 2005021705 A3 WO2005021705 A3 WO 2005021705A3
Authority
WO
WIPO (PCT)
Prior art keywords
sequences
production
methods
citrus
present
Prior art date
Application number
PCT/IL2004/000795
Other languages
French (fr)
Other versions
WO2005021705A9 (en
WO2005021705A2 (en
WO2005021705A8 (en
Inventor
Yoram Eyal
Efraim Lewinsohn
Original Assignee
Israel State
Yoram Eyal
Efraim Lewinsohn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Israel State, Yoram Eyal, Efraim Lewinsohn filed Critical Israel State
Priority to AU2004269197A priority Critical patent/AU2004269197A1/en
Priority to JP2006525264A priority patent/JP2007517496A/en
Priority to CA002537505A priority patent/CA2537505A1/en
Priority to EP04770466A priority patent/EP1659996A4/en
Publication of WO2005021705A2 publication Critical patent/WO2005021705A2/en
Publication of WO2005021705A3 publication Critical patent/WO2005021705A3/en
Publication of WO2005021705A8 publication Critical patent/WO2005021705A8/en
Priority to IL174039A priority patent/IL174039A0/en
Publication of WO2005021705A9 publication Critical patent/WO2005021705A9/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)

Abstract

The present invention relates to citrus sesquiterpene synthases, key enzymes in the production of valencene, a sesquiterpene aromatic compound. Particularly, the present invention relates to nucleic acid sequences encoding valecene synthases from angiosperm plant species, in particular citrus, vectors containing the sequences, host cells containing said sequences and transgenic plants expressing said sequences. The present invention further relates to methods of producing recombinant valencene synthase and its products, and uses thereof.
PCT/IL2004/000795 2003-09-02 2004-09-02 Citrus sesquiterpene synthase, methods of production and uses thereof WO2005021705A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AU2004269197A AU2004269197A1 (en) 2003-09-02 2004-09-02 Citrus sesquiterpene synthase, methods of production and uses thereof
JP2006525264A JP2007517496A (en) 2003-09-02 2004-09-02 Citrus sesquiterpene synthase, method for its production, and method of use
CA002537505A CA2537505A1 (en) 2003-09-02 2004-09-02 Citrus sesquiterpene synthase, methods of production and uses thereof
EP04770466A EP1659996A4 (en) 2003-09-02 2004-09-02 Citrus sesquiterpene synthase, methods of production and uses thereof
IL174039A IL174039A0 (en) 2003-09-02 2006-03-01 Citrus sesquiterpene synthase, methods of production and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49902403P 2003-09-02 2003-09-02
US60/499,024 2003-09-02

Publications (4)

Publication Number Publication Date
WO2005021705A2 WO2005021705A2 (en) 2005-03-10
WO2005021705A3 true WO2005021705A3 (en) 2005-04-21
WO2005021705A8 WO2005021705A8 (en) 2005-12-22
WO2005021705A9 WO2005021705A9 (en) 2009-04-16

Family

ID=34272763

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2004/000795 WO2005021705A2 (en) 2003-09-02 2004-09-02 Citrus sesquiterpene synthase, methods of production and uses thereof

Country Status (5)

Country Link
EP (1) EP1659996A4 (en)
JP (1) JP2007517496A (en)
AU (1) AU2004269197A1 (en)
CA (1) CA2537505A1 (en)
WO (1) WO2005021705A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE546521T1 (en) * 2002-10-04 2012-03-15 Firmenich & Cie SESQUITERPENE SYNTHASES AND METHODS OF USE
US7442785B2 (en) 2003-07-24 2008-10-28 The University Of Kentucky Research Foundation Sesquiterpene synthase gene and protein
WO2009109597A1 (en) * 2008-03-06 2009-09-11 Firmenich Sa Method for producing alpha- santalene
JP5649020B2 (en) * 2008-10-10 2015-01-07 国立大学法人岩手大学 Repression of soybean endogenous gene expression by recombinant ALSV
CN103282492A (en) 2010-10-29 2013-09-04 奥利里克斯股份有限公司 Modified valencene synthase polypeptides, encoding nucleic acid molecules and uses thereof
EP2537926A1 (en) * 2011-06-21 2012-12-26 Isobionics B.V. Valencene synthase
US20150250166A1 (en) 2012-08-23 2015-09-10 Allylix, Inc. Nootkatone as an insecticide and insect repellent
EP3085778B1 (en) 2013-03-14 2021-07-07 Evolva, Inc. Valencene synthase polypeptides, encoding nucleic acid molecules and uses thereof
ES2540791B1 (en) * 2013-12-13 2016-05-09 Consejo Superior De Investigaciones Científicas (Csic) New sesquiterpene synthases isolated from orange peel.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4970085A (en) 1989-10-19 1990-11-13 The Procter & Gamble Company Process for making improved citrus aqueous essence and product produced therefrom
CN1703507B (en) * 2002-10-04 2010-09-29 弗门尼舍有限公司 Sesquiterpene synthases and methods of use
US7442785B2 (en) * 2003-07-24 2008-10-28 The University Of Kentucky Research Foundation Sesquiterpene synthase gene and protein

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CLVERT ET AL.: "Germacrene A is a Product of the Aristolochene Synthase-Mediated Conversion of Farnesylpyrophoshate to Aristolochene", J. AM. CHEM. SOC., vol. 124, 2002, pages 11636 - 11641 *
DATABASE EMBL [online] XIA ET AL.: "Identification of a gene highly expressed in juice vesicles of mature Rio Red grapefruit using differential display", accession no. EBI Database accession no. AF411120 *
See also references of EP1659996A4 *

Also Published As

Publication number Publication date
WO2005021705A9 (en) 2009-04-16
AU2004269197A1 (en) 2005-03-10
EP1659996A2 (en) 2006-05-31
EP1659996A4 (en) 2008-07-02
WO2005021705A2 (en) 2005-03-10
JP2007517496A (en) 2007-07-05
WO2005021705A8 (en) 2005-12-22
CA2537505A1 (en) 2005-03-10

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