BR112013026828A2 - polipeptídeos de anticorpo que antagonizam cd40 - Google Patents

polipeptídeos de anticorpo que antagonizam cd40

Info

Publication number
BR112013026828A2
BR112013026828A2 BR112013026828A BR112013026828A BR112013026828A2 BR 112013026828 A2 BR112013026828 A2 BR 112013026828A2 BR 112013026828 A BR112013026828 A BR 112013026828A BR 112013026828 A BR112013026828 A BR 112013026828A BR 112013026828 A2 BR112013026828 A2 BR 112013026828A2
Authority
BR
Brazil
Prior art keywords
antibody polypeptides
antibody
domain
polypeptides
antagonizing
Prior art date
Application number
BR112013026828A
Other languages
English (en)
Portuguese (pt)
Inventor
Aaron Yamniuk
Anish Suri
James Bryson
James Tamura
Philip Drew
Stanley Krystek
Steven Grant
Steven Sheriff
Suzanne Suchard
Original Assignee
Bristol Myers Squibb Co
Domantis Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46000407&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112013026828(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Co, Domantis Ltd filed Critical Bristol Myers Squibb Co
Publication of BR112013026828A2 publication Critical patent/BR112013026828A2/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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