BR112013024686A2 - ensaio de psa, e, reagente de ensaio de psa - Google Patents
ensaio de psa, e, reagente de ensaio de psaInfo
- Publication number
- BR112013024686A2 BR112013024686A2 BR112013024686A BR112013024686A BR112013024686A2 BR 112013024686 A2 BR112013024686 A2 BR 112013024686A2 BR 112013024686 A BR112013024686 A BR 112013024686A BR 112013024686 A BR112013024686 A BR 112013024686A BR 112013024686 A2 BR112013024686 A2 BR 112013024686A2
- Authority
- BR
- Brazil
- Prior art keywords
- psa
- assay
- reagent
- psa assay
- vehicles
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
- G01N33/545—Synthetic resin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57434—Specifically defined cancers of prostate
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96433—Serine endopeptidases (3.4.21)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
1ensaio de psa, e, reagente de ensaio de psa descreve-se um método para o ensaio simples e altamente preciso de psa por uma reação em uma etapa não usa veículos tendo diferentes tamanhos médios de partícula. também é descrito um reagente para o mesmo. o método de ensaio de psa compreende usar veículos insolúveis, com o mesmo tamanho médio de partícula dentro da faixa maior do que 0,20 <109>m, mas de 0,40 <109>m ou menor, imobilizando sobre os mesmos dois tipos de anticorpos monoclonais anti-psa e reconhecendo diferentes epítopos, que são anticorpos monoclonais anti-psa que irão reagir tanto com psa livre como psa-act, que é um complexo de psa livre de <244>1-antiquimotripsina e levando os veículos ao contato com uma amostra na presença de um acelerador de aglutinação.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011-069161 | 2011-03-28 | ||
| JP2011069161 | 2011-03-28 | ||
| PCT/JP2012/058056 WO2012133482A1 (ja) | 2011-03-28 | 2012-03-28 | Psaの測定方法及びその試薬 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BR112013024686A2 true BR112013024686A2 (pt) | 2016-12-20 |
| BR112013024686B1 BR112013024686B1 (pt) | 2020-12-29 |
| BR112013024686B8 BR112013024686B8 (pt) | 2022-05-03 |
Family
ID=46931192
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013024686A BR112013024686B8 (pt) | 2011-03-28 | 2012-03-28 | Ensaio de psa, e, reagente de ensaio de psa |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20140080143A1 (pt) |
| EP (1) | EP2698633B1 (pt) |
| JP (1) | JP6110786B2 (pt) |
| KR (1) | KR101835918B1 (pt) |
| CN (2) | CN105424936B (pt) |
| AU (1) | AU2012233635B2 (pt) |
| BR (1) | BR112013024686B8 (pt) |
| CA (1) | CA2831398C (pt) |
| MX (1) | MX347002B (pt) |
| MY (1) | MY165647A (pt) |
| WO (1) | WO2012133482A1 (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6188577B2 (ja) * | 2011-12-28 | 2017-08-30 | 積水メディカル株式会社 | 粒子凝集測定用ラテックス粒子 |
| EP2902782B1 (en) * | 2012-09-28 | 2019-02-27 | Sekisui Medical Co., Ltd. | Immunological detection process and reagent for immunological detection process |
| CN105640991A (zh) * | 2016-01-06 | 2016-06-08 | 奥思达干细胞有限公司 | 一种治疗前列腺癌的car-t细胞制剂及其制备方法 |
| WO2018138264A2 (en) * | 2017-01-27 | 2018-08-02 | Roche Diagnostics Gmbh | Methods for modulating signal intensity in interaction assays |
| BR112020005335A2 (pt) * | 2017-09-19 | 2020-09-24 | Regeneron Pharmaceuticals, Inc. | métodos para reduzir a formação de partículas e composições formadas pelos mesmos |
| CN108802392A (zh) * | 2018-08-29 | 2018-11-13 | 上海市东方医院 | 一种用于诊断前列腺癌的层析试纸条及其制备方法和应用 |
| US20210382041A1 (en) * | 2018-10-09 | 2021-12-09 | Sekisui Medical Co., Ltd. | Immunoassay and measurement reagent for leucine-rich alpha2 glycoprotein |
| CN117192134A (zh) * | 2023-09-14 | 2023-12-08 | 宁波美康盛德生物科技有限公司 | 一种氧化型低密度脂蛋白的检测试剂盒、检测方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9002480D0 (sv) | 1990-07-23 | 1990-07-23 | Hans Lilja | Assay of free and complexed prostate-specific antigen |
| US5185264A (en) * | 1990-11-09 | 1993-02-09 | Abbott Laboratories | Diluent buffer and method for diluting an assay component |
| EP0789032A2 (en) * | 1996-02-01 | 1997-08-13 | Bayer Corporation | Method for preparing a monoclonal antibody that provides an equimolar response to free and complexed analyte in a monoclonal/polyclonal sandwich immunoassay |
| JP3652029B2 (ja) * | 1996-10-16 | 2005-05-25 | 積水化学工業株式会社 | 高感度免疫測定法 |
| JP2001108681A (ja) | 1999-10-07 | 2001-04-20 | Sysmex Corp | 免疫凝集測定用試薬及び測定方法 |
| JP4577747B2 (ja) * | 2001-06-05 | 2010-11-10 | 和光純薬工業株式会社 | 免疫学的測定法用凝集促進剤 |
| CN100396331C (zh) | 2001-07-02 | 2008-06-25 | 积水化学工业株式会社 | 用于分析试剂的载体颗粒胶乳和分析试剂 |
| JP4241301B2 (ja) * | 2003-09-30 | 2009-03-18 | 和光純薬工業株式会社 | 免疫学的測定用試薬 |
| JP4755112B2 (ja) * | 2004-12-24 | 2011-08-24 | 積水メディカル株式会社 | 抗原を測定するための試薬及び抗原の測定方法 |
| WO2007066731A1 (ja) * | 2005-12-07 | 2007-06-14 | Sekisui Medical Co., Ltd. | 抗リン脂質抗体測定試薬及び抗トレポネーマ・パリダム抗体測定試薬 |
| JP2007163319A (ja) * | 2005-12-14 | 2007-06-28 | Sanyo Chem Ind Ltd | 免疫測定法及び免疫測定用試薬キット |
| CN101351707B (zh) * | 2005-12-28 | 2014-03-26 | 积水医疗株式会社 | 凝集测量用试剂以及凝集测量方法 |
| EP2068148B1 (en) | 2006-07-24 | 2014-03-26 | Sekisui Medical Co., Ltd. | Method of measuring anticoagulation and reagent for measuring anticoagulation |
| US20100330600A1 (en) * | 2008-02-29 | 2010-12-30 | Sekisui Medical Co., Ltd. | High-molecular-weight adiponectin measurement method |
| WO2010001619A1 (ja) * | 2008-07-04 | 2010-01-07 | 積水メディカル株式会社 | 免疫学的測定における感度増強方法又はヘモグロビンの影響回避方法 |
| CA2745610C (en) | 2008-12-04 | 2017-10-31 | Sekisui Medical Co., Ltd. | Method for measuring cystatin c in human body fluid |
| JP6188577B2 (ja) * | 2011-12-28 | 2017-08-30 | 積水メディカル株式会社 | 粒子凝集測定用ラテックス粒子 |
| WO2013147306A1 (ja) * | 2012-03-30 | 2013-10-03 | 積水メディカル株式会社 | 粒子凝集測定用ラテックス粒子 |
| CN104662426B (zh) * | 2012-09-27 | 2017-06-13 | 积水医疗株式会社 | 粒子凝集测定用胶乳粒子 |
-
2012
- 2012-03-28 WO PCT/JP2012/058056 patent/WO2012133482A1/ja active Application Filing
- 2012-03-28 MX MX2013011090A patent/MX347002B/es active IP Right Grant
- 2012-03-28 CA CA2831398A patent/CA2831398C/en active Active
- 2012-03-28 EP EP12763300.6A patent/EP2698633B1/en active Active
- 2012-03-28 CN CN201510964173.XA patent/CN105424936B/zh active Active
- 2012-03-28 MY MYPI2013701753A patent/MY165647A/en unknown
- 2012-03-28 CN CN2012800146962A patent/CN103443628A/zh active Pending
- 2012-03-28 BR BR112013024686A patent/BR112013024686B8/pt active IP Right Grant
- 2012-03-28 JP JP2013507648A patent/JP6110786B2/ja active Active
- 2012-03-28 KR KR1020137027855A patent/KR101835918B1/ko active IP Right Grant
- 2012-03-28 AU AU2012233635A patent/AU2012233635B2/en active Active
- 2012-03-28 US US14/008,441 patent/US20140080143A1/en not_active Abandoned
-
2015
- 2015-09-25 US US14/865,728 patent/US10119963B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN105424936B (zh) | 2018-09-21 |
| JP6110786B2 (ja) | 2017-04-05 |
| CA2831398C (en) | 2020-06-09 |
| BR112013024686B8 (pt) | 2022-05-03 |
| JPWO2012133482A1 (ja) | 2014-07-28 |
| CA2831398A1 (en) | 2012-10-04 |
| EP2698633A4 (en) | 2014-12-17 |
| MX2013011090A (es) | 2013-12-16 |
| US10119963B2 (en) | 2018-11-06 |
| KR20140015488A (ko) | 2014-02-06 |
| KR101835918B1 (ko) | 2018-03-07 |
| US20160011181A1 (en) | 2016-01-14 |
| EP2698633B1 (en) | 2017-10-11 |
| MX347002B (es) | 2017-04-07 |
| BR112013024686B1 (pt) | 2020-12-29 |
| CN105424936A (zh) | 2016-03-23 |
| US20140080143A1 (en) | 2014-03-20 |
| CN103443628A (zh) | 2013-12-11 |
| MY165647A (en) | 2018-04-18 |
| AU2012233635B2 (en) | 2016-09-08 |
| WO2012133482A1 (ja) | 2012-10-04 |
| EP2698633A1 (en) | 2014-02-19 |
| AU2012233635A1 (en) | 2013-10-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B25G | Requested change of headquarter approved |
Owner name: SEKISUI MEDICAL CO., LTD. (JP) |
|
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 28/03/2012, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: REF. RPI 2608 DE 29/12/2020 QUANTO AOS INVENTORES. |