BR112013022915A2 - célula geneticamente modificada, vetor, processo de conversão de ácido 5-(hidroximetil) furan-2-carboxílico (ácido hmf), e uso de uma célula geneticamente modificada - Google Patents

célula geneticamente modificada, vetor, processo de conversão de ácido 5-(hidroximetil) furan-2-carboxílico (ácido hmf), e uso de uma célula geneticamente modificada

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Publication number
BR112013022915A2
BR112013022915A2 BR112013022915A BR112013022915A BR112013022915A2 BR 112013022915 A2 BR112013022915 A2 BR 112013022915A2 BR 112013022915 A BR112013022915 A BR 112013022915A BR 112013022915 A BR112013022915 A BR 112013022915A BR 112013022915 A2 BR112013022915 A2 BR 112013022915A2
Authority
BR
Brazil
Prior art keywords
genetically modified
modified cell
hmf
furan
hydroxymethyl
Prior art date
Application number
BR112013022915A
Other languages
English (en)
Other versions
BR112013022915B1 (pt
Inventor
Harald Johan Ruijssenaars
Nick Johannes Petrus Wierckx
Sipko Maarten Kuijper
Tom Daniël Elink Schuurman
Original Assignee
Purac Biochem Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purac Biochem Bv filed Critical Purac Biochem Bv
Publication of BR112013022915A2 publication Critical patent/BR112013022915A2/pt
Publication of BR112013022915B1 publication Critical patent/BR112013022915B1/pt

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0008Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • C12P17/04Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y102/00Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BR112013022915-2A 2011-03-08 2012-03-07 Célula geneticamente modificada, vetor, processo de conversão de ácido 5-(hidroximetil) furan-2-carboxílico (ácido hmf), e uso de uma célula geneticamente modificada BR112013022915B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NL2006359 2011-03-08
NL2006359A NL2006359C2 (en) 2011-03-08 2011-03-08 Genetically modified cell and process for use of said cell.
PCT/NL2012/050141 WO2012064195A2 (en) 2011-03-08 2012-03-07 Genetically modified cell and process for use of said cell

Publications (2)

Publication Number Publication Date
BR112013022915A2 true BR112013022915A2 (pt) 2016-12-06
BR112013022915B1 BR112013022915B1 (pt) 2021-08-31

Family

ID=45873204

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013022915-2A BR112013022915B1 (pt) 2011-03-08 2012-03-07 Célula geneticamente modificada, vetor, processo de conversão de ácido 5-(hidroximetil) furan-2-carboxílico (ácido hmf), e uso de uma célula geneticamente modificada

Country Status (19)

Country Link
US (3) US9309546B2 (pt)
EP (1) EP2683815B1 (pt)
JP (2) JP6017463B2 (pt)
KR (1) KR101947202B1 (pt)
CN (1) CN103502441B (pt)
AU (1) AU2012202889B2 (pt)
BR (1) BR112013022915B1 (pt)
CA (1) CA2829078C (pt)
DK (1) DK2683815T3 (pt)
EA (1) EA023764B9 (pt)
ES (1) ES2543568T3 (pt)
HU (1) HUE027066T2 (pt)
MX (1) MX336694B (pt)
MY (1) MY161455A (pt)
NL (1) NL2006359C2 (pt)
PL (1) PL2683815T3 (pt)
PT (1) PT2683815E (pt)
SI (1) SI2683815T1 (pt)
WO (1) WO2012064195A2 (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL2006359C2 (en) * 2011-03-08 2012-04-24 Bird Engineering B V Genetically modified cell and process for use of said cell.
US20150152452A1 (en) * 2012-07-20 2015-06-04 Novozymes A/S Enzymatic Oxidation of 5-Hydroxymethylfurfural and Derivatives Thereof
US9528133B2 (en) 2012-09-21 2016-12-27 Synthetic Genomics, Inc. Compositions and methods for producing chemicals and derivatives thereof
CN104769122B (zh) 2012-09-21 2018-08-10 合成基因组股份有限公司 用于生产化学品和其衍生物的组合物和方法
WO2014081973A1 (en) 2012-11-21 2014-05-30 The Regents Of The University Of California Nucleic acids useful for integrating into and gene expression in hyperthermophilic acidophilic archaea
NL2011027C2 (en) 2013-06-24 2014-12-29 Univ Delft Tech Process for the preparation of 2,5-furandicarboxylic acid.
CN104371955B (zh) * 2014-10-30 2017-02-08 江南大学 一种合成2,5‑呋喃二甲酸的土生拉乌尔菌及其应用
EP3259349B1 (en) * 2015-02-17 2020-06-17 Purac Biochem B.V. Dehydrogenase-catalysed production of fdca
WO2017050815A1 (en) 2015-09-21 2017-03-30 Purac Biochem B.V. Fungal production of fdca
JP7071283B2 (ja) * 2016-12-20 2022-05-18 株式会社カネカ ポリヒドロキシアルカン酸の製造方法及び微生物
EP3366681A1 (en) 2017-02-28 2018-08-29 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO Production of 2,5-furandicarboxylic acid
EP3378931A1 (en) * 2017-03-21 2018-09-26 Purac Biochem B.V. Fdca-decarboxylating monooxygenase-deficient host cells for producing fdca
CN109609397A (zh) * 2017-10-31 2019-04-12 天津科技大学 一种水产养殖用复合微生物菌剂及应用
WO2019094740A1 (en) 2017-11-10 2019-05-16 Shell Oil Company Methods of producing 2,5-furandicarboxylic acid
EP3732174B1 (en) 2017-12-29 2023-12-27 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk Onderzoek TNO Method for purifying and removing colour of 2,5-furandicarboxylic acid (fdca)
EP3505514A1 (en) 2017-12-29 2019-07-03 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO Method for purifying and removing color of 2,5-furandicarboxylic acid (fdca)
US11339414B2 (en) * 2019-03-01 2022-05-24 Braskem S.A. Method for the in vivo synthesis of 4-hydroxymethylfurfural and derivatives thereof
CN110591995A (zh) * 2019-09-12 2019-12-20 华南理工大学 一种共表达重组菌及其在合成呋喃羧酸中的应用
CN110724654B (zh) * 2019-11-22 2020-09-29 南京科技职业学院 一株生产5-羟甲基-2呋喃甲酸的铜绿假单胞菌及其应用
TWI735113B (zh) * 2019-12-23 2021-08-01 國立清華大學 2,5-呋喃二甲酸之製備方法
NL2024726B1 (en) 2020-01-22 2021-09-09 Biomosae B V Enzymatic crop protection and process for preparing biological crop protection composition
US20240011990A1 (en) 2020-07-17 2024-01-11 Trustees Of Boston University Viral detection systems and uses thereof
US20240115607A1 (en) 2021-01-26 2024-04-11 Cytocares (Shanghai) Inc. Chimeric antigen receptor (car) constructs and nk cells expressing car constructs

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2295534A1 (en) * 2009-09-02 2011-03-16 Shell Internationale Research Maatschappij B.V. Novel microorganism and its use in lignocellulose detoxification
IN2012DN01652A (pt) * 2009-09-02 2015-06-05 Dsm Ip Assets Bv
NL2006359C2 (en) * 2011-03-08 2012-04-24 Bird Engineering B V Genetically modified cell and process for use of said cell.

Also Published As

Publication number Publication date
EP2683815B1 (en) 2015-05-20
HUE027066T2 (en) 2016-08-29
EP2683815A2 (en) 2014-01-15
US10023890B2 (en) 2018-07-17
ES2543568T3 (es) 2015-08-20
WO2012064195A2 (en) 2012-05-18
JP2017060471A (ja) 2017-03-30
AU2012202889B2 (en) 2016-09-15
PL2683815T3 (pl) 2015-10-30
WO2012064195A3 (en) 2012-08-23
BR112013022915B1 (pt) 2021-08-31
KR101947202B1 (ko) 2019-02-12
DK2683815T3 (en) 2015-07-20
US20180023105A1 (en) 2018-01-25
MX336694B (es) 2016-01-27
MX2013010226A (es) 2014-01-08
EA023764B9 (ru) 2016-10-31
US9309546B2 (en) 2016-04-12
NL2006359C2 (en) 2012-04-24
SI2683815T1 (sl) 2015-09-30
US9828616B2 (en) 2017-11-28
AU2012202889A1 (en) 2013-09-26
CN103502441B (zh) 2016-09-14
US20160257978A1 (en) 2016-09-08
KR20140015439A (ko) 2014-02-06
EA201300999A1 (ru) 2014-02-28
US20140073019A1 (en) 2014-03-13
CA2829078C (en) 2021-12-28
MY161455A (en) 2017-04-14
CA2829078A1 (en) 2012-05-18
JP6327724B2 (ja) 2018-05-23
PT2683815E (pt) 2015-09-18
JP2014508531A (ja) 2014-04-10
JP6017463B2 (ja) 2016-11-02
EA023764B1 (ru) 2016-07-29
CN103502441A (zh) 2014-01-08

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 07/03/2012, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

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B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2713 DE 03-01-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.