BR112013011194B1 - partícula micelar, composição farmacêutica compreendendo a mesma, uso de uma partícula micelar e método de preparação de uma micela - Google Patents

partícula micelar, composição farmacêutica compreendendo a mesma, uso de uma partícula micelar e método de preparação de uma micela Download PDF

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Publication number
BR112013011194B1
BR112013011194B1 BR112013011194-1A BR112013011194A BR112013011194B1 BR 112013011194 B1 BR112013011194 B1 BR 112013011194B1 BR 112013011194 A BR112013011194 A BR 112013011194A BR 112013011194 B1 BR112013011194 B1 BR 112013011194B1
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BR
Brazil
Prior art keywords
proteins
protein
vlps
cells
glycoproteins
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BR112013011194-1A
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English (en)
Portuguese (pt)
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BR112013011194A2 (pt
Inventor
Gale Smith
Ye Liu
Original Assignee
Novavax, Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novavax, Inc filed Critical Novavax, Inc
Publication of BR112013011194A2 publication Critical patent/BR112013011194A2/pt
Publication of BR112013011194B1 publication Critical patent/BR112013011194B1/pt

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/205Rhabdoviridae, e.g. rabies virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5258Virus-like particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/20011Rhabdoviridae
    • C12N2760/20111Lyssavirus, e.g. rabies virus
    • C12N2760/20134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BR112013011194-1A 2010-11-05 2011-11-07 partícula micelar, composição farmacêutica compreendendo a mesma, uso de uma partícula micelar e método de preparação de uma micela BR112013011194B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41076710P 2010-11-05 2010-11-05
US61/410,767 2010-11-05
PCT/US2011/059602 WO2012061815A2 (en) 2010-11-05 2011-11-07 RABIES GLYCOPROTEIN VIRUS-LIKE PARTICLES (VLPs)

Publications (2)

Publication Number Publication Date
BR112013011194A2 BR112013011194A2 (pt) 2017-06-27
BR112013011194B1 true BR112013011194B1 (pt) 2020-12-22

Family

ID=46025156

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013011194-1A BR112013011194B1 (pt) 2010-11-05 2011-11-07 partícula micelar, composição farmacêutica compreendendo a mesma, uso de uma partícula micelar e método de preparação de uma micela

Country Status (22)

Country Link
US (3) US9724405B2 (https=)
EP (2) EP2635257B1 (https=)
JP (2) JP6158088B2 (https=)
KR (1) KR101847908B1 (https=)
CN (2) CN109157658A (https=)
AU (1) AU2011323090B2 (https=)
BR (1) BR112013011194B1 (https=)
CA (1) CA2817005C (https=)
CY (1) CY1119284T1 (https=)
DK (1) DK2635257T3 (https=)
ES (1) ES2636965T3 (https=)
HR (1) HRP20171213T1 (https=)
HU (1) HUE034247T2 (https=)
LT (1) LT2635257T (https=)
MX (1) MX354750B (https=)
PL (1) PL2635257T3 (https=)
PT (1) PT2635257T (https=)
RS (1) RS56157B1 (https=)
SG (1) SG190140A1 (https=)
SI (1) SI2635257T1 (https=)
SM (1) SMT201700392T1 (https=)
WO (1) WO2012061815A2 (https=)

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CN120227451A (zh) 2018-03-19 2025-07-01 诺瓦瓦克斯股份有限公司 多价流感纳米颗粒疫苗
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KR102211077B1 (ko) * 2019-01-16 2021-02-02 충남대학교 산학협력단 바이러스 유사 입자를 이용한 슈도-타입 광견병 백신
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Also Published As

Publication number Publication date
CA2817005C (en) 2018-09-11
EP2635257B1 (en) 2017-07-05
JP6158088B2 (ja) 2017-07-05
CA2817005A1 (en) 2012-05-10
AU2011323090B2 (en) 2015-02-12
ES2636965T3 (es) 2017-10-10
AU2011323090A1 (en) 2013-04-04
BR112013011194A2 (pt) 2017-06-27
US9724405B2 (en) 2017-08-08
RU2013125695A (ru) 2014-12-10
EP3246019B1 (en) 2021-03-03
US20180021428A1 (en) 2018-01-25
US10086065B2 (en) 2018-10-02
HUE034247T2 (en) 2018-02-28
PT2635257T (pt) 2017-08-16
EP2635257A4 (en) 2014-04-02
LT2635257T (lt) 2017-09-25
CN103282023B (zh) 2018-09-21
CY1119284T1 (el) 2018-02-14
JP2017035093A (ja) 2017-02-16
CN109157658A (zh) 2019-01-08
JP6195965B2 (ja) 2017-09-13
SMT201700392T1 (it) 2017-09-07
PL2635257T3 (pl) 2017-10-31
KR20130111581A (ko) 2013-10-10
WO2012061815A3 (en) 2013-03-14
KR101847908B1 (ko) 2018-04-11
EP3246019A1 (en) 2017-11-22
DK2635257T3 (en) 2017-09-04
US20140178419A1 (en) 2014-06-26
HRP20171213T1 (hr) 2017-10-20
SI2635257T1 (en) 2018-01-31
SG190140A1 (en) 2013-06-28
WO2012061815A2 (en) 2012-05-10
JP2014500013A (ja) 2014-01-09
MX2013005090A (es) 2013-10-25
EP2635257A2 (en) 2013-09-11
CN103282023A (zh) 2013-09-04
MX354750B (es) 2018-03-20
RS56157B1 (sr) 2017-11-30
US20190224307A1 (en) 2019-07-25

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