BR112013010990A2 - processo para a preparação de n-(benzil) ciclopanaminas, uso e derivados - Google Patents
processo para a preparação de n-(benzil) ciclopanaminas, uso e derivadosInfo
- Publication number
- BR112013010990A2 BR112013010990A2 BR112013010990A BR112013010990A BR112013010990A2 BR 112013010990 A2 BR112013010990 A2 BR 112013010990A2 BR 112013010990 A BR112013010990 A BR 112013010990A BR 112013010990 A BR112013010990 A BR 112013010990A BR 112013010990 A2 BR112013010990 A2 BR 112013010990A2
- Authority
- BR
- Brazil
- Prior art keywords
- cyclopanamines
- benzyl
- derivatives
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/44—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers
- C07C209/52—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of imines or imino-ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C211/34—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton
- C07C211/35—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton containing only non-condensed rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/58—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms with amino groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/04—Formation of amino groups in compounds containing carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
- C07C251/24—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41051710P | 2010-11-05 | 2010-11-05 | |
| EP10190077 | 2010-11-05 | ||
| EP10190077.7 | 2010-11-05 | ||
| US61/410,517 | 2010-11-05 | ||
| PCT/EP2011/069426 WO2012059585A1 (en) | 2010-11-05 | 2011-11-04 | Process for the preparation of substituted n-(benzyl)cyclopropanamines by imine hydrogenation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112013010990A2 true BR112013010990A2 (pt) | 2016-08-30 |
| BR112013010990B1 BR112013010990B1 (pt) | 2019-03-26 |
Family
ID=43805674
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013010990-4A BR112013010990B1 (pt) | 2010-11-05 | 2011-11-04 | Processo para a preparação de n-(benzil)ciclopropanaminas, processo para a preparaçãodos derivados de n-[(aril)metileno]ciclopropanamina e derivados de n-[(aril)metileno]ciclopropanamina |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9260378B2 (pt) |
| EP (1) | EP2635551B1 (pt) |
| JP (1) | JP2014503481A (pt) |
| KR (1) | KR101874659B1 (pt) |
| CN (1) | CN103402970B (pt) |
| BR (1) | BR112013010990B1 (pt) |
| DK (1) | DK2635551T3 (pt) |
| ES (1) | ES2680546T3 (pt) |
| IL (1) | IL226132B (pt) |
| MX (1) | MX2013004881A (pt) |
| TW (2) | TWI622573B (pt) |
| WO (1) | WO2012059585A1 (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI589550B (zh) | 2012-04-26 | 2017-07-01 | 拜耳作物科學公司 | 製備ｎ－（５－氯－２－異丙基苄基）環丙胺之方法 |
| CN107428675A (zh) * | 2015-03-11 | 2017-12-01 | 三菱瓦斯化学株式会社 | 新型多胺化合物及其制造方法，以及使用其的环氧树脂用固化剂、环氧树脂组合物和环氧树脂固化物 |
| US9958781B2 (en) * | 2015-04-24 | 2018-05-01 | Jsr Corporation | Method for film formation, and pattern-forming method |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3083226A (en) * | 1961-10-18 | 1963-03-26 | Abbott Lab | N-benzyl cyclopropylamines and carbamates |
| US3153093A (en) * | 1961-11-22 | 1964-10-13 | Abbott Lab | Amino derivatives of nu-cyclopropylbenzylamines |
| US6252090B1 (en) * | 2000-08-29 | 2001-06-26 | Allergan Sales, Inc. | Compounds having activity as inhibitors of cytochrome P450RAI |
| CA2498091C (en) | 2002-10-11 | 2011-03-22 | Actelion Pharmaceuticals Ltd. | Sulfonylamino-acetic acid derivatives |
| GB0428250D0 (en) | 2004-12-23 | 2005-01-26 | Novartis Ag | Organic compounds |
| AR056882A1 (es) | 2006-02-01 | 2007-10-31 | Bayer Cropscience Sa | Derivados del fungicida n- cicloalquil- bencil- amida |
| CA2663500A1 (en) * | 2006-09-15 | 2008-03-20 | Schering Corporation | Spiro-condensed azetidine derivatives useful in treating pain, diabetes and disorders of lipid metabolism |
| JP2010503677A (ja) | 2006-09-15 | 2010-02-04 | シェーリング コーポレイション | 脂質代謝の障害を治療するためのアゼチジノン誘導体 |
| WO2008087933A1 (ja) * | 2007-01-15 | 2008-07-24 | Santen Pharmaceutical Co., Ltd. | ＩκＢキナーゼβ阻害活性を有する新規インドール誘導体 |
| CN103450077B (zh) * | 2007-06-08 | 2016-07-06 | 满康德股份有限公司 | IRE-1α抑制剂 |
| JP4790871B2 (ja) * | 2008-05-05 | 2011-10-12 | メルク フロスト カナダ リミテツド | レニン阻害剤としての３，４−置換ピペリジン誘導体 |
| TWI589550B (zh) * | 2012-04-26 | 2017-07-01 | 拜耳作物科學公司 | 製備ｎ－（５－氯－２－異丙基苄基）環丙胺之方法 |
-
2011
- 2011-10-19 TW TW105128670A patent/TWI622573B/zh active
- 2011-10-19 TW TW100137972A patent/TWI562977B/zh active
- 2011-11-04 BR BR112013010990-4A patent/BR112013010990B1/pt active IP Right Grant
- 2011-11-04 JP JP2013537149A patent/JP2014503481A/ja active Pending
- 2011-11-04 MX MX2013004881A patent/MX2013004881A/es active IP Right Grant
- 2011-11-04 EP EP11778894.3A patent/EP2635551B1/en active Active
- 2011-11-04 KR KR1020137014336A patent/KR101874659B1/ko active IP Right Grant
- 2011-11-04 ES ES11778894.3T patent/ES2680546T3/es active Active
- 2011-11-04 DK DK11778894.3T patent/DK2635551T3/en active
- 2011-11-04 CN CN201180053177.2A patent/CN103402970B/zh active Active
- 2011-11-04 WO PCT/EP2011/069426 patent/WO2012059585A1/en active Application Filing
- 2011-11-04 US US13/883,241 patent/US9260378B2/en active Active
-
2013
- 2013-05-02 IL IL226132A patent/IL226132B/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| KR20130115290A (ko) | 2013-10-21 |
| TWI562977B (en) | 2016-12-21 |
| MX2013004881A (es) | 2013-07-02 |
| CN103402970B (zh) | 2017-02-15 |
| US20130217910A1 (en) | 2013-08-22 |
| CN103402970A (zh) | 2013-11-20 |
| BR112013010990B1 (pt) | 2019-03-26 |
| IL226132B (en) | 2018-02-28 |
| DK2635551T3 (en) | 2018-08-06 |
| ES2680546T3 (es) | 2018-09-10 |
| KR101874659B1 (ko) | 2018-07-04 |
| TWI622573B (zh) | 2018-05-01 |
| WO2012059585A1 (en) | 2012-05-10 |
| TW201249780A (en) | 2012-12-16 |
| TW201700451A (zh) | 2017-01-01 |
| EP2635551A1 (en) | 2013-09-11 |
| IL226132A0 (en) | 2013-06-27 |
| US9260378B2 (en) | 2016-02-16 |
| EP2635551B1 (en) | 2018-05-02 |
| JP2014503481A (ja) | 2014-02-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 04/11/2011, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B25A | Requested transfer of rights approved |
Owner name: BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) |