BR112012027432A2 - composições farmacêuticas com agentes antimicrobianos de fosfônio - Google Patents

composições farmacêuticas com agentes antimicrobianos de fosfônio

Info

Publication number
BR112012027432A2
BR112012027432A2 BR112012027432A BR112012027432A BR112012027432A2 BR 112012027432 A2 BR112012027432 A2 BR 112012027432A2 BR 112012027432 A BR112012027432 A BR 112012027432A BR 112012027432 A BR112012027432 A BR 112012027432A BR 112012027432 A2 BR112012027432 A2 BR 112012027432A2
Authority
BR
Brazil
Prior art keywords
pharmaceutical compositions
phosphonium
antimicrobial agents
phosphonium antimicrobial
relates
Prior art date
Application number
BR112012027432A
Other languages
English (en)
Inventor
L Wayne Schneider
Masood A Chowhan
Wesley Wehsin Han
Original Assignee
Alcon Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Res Ltd filed Critical Alcon Res Ltd
Publication of BR112012027432A2 publication Critical patent/BR112012027432A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/42—Phosphorus; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0046—Ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

composições farmacêuticas com agentes antimicrobianos de fosfônio. a presente invenção, refere-se a composições farmacêuticas que incluem um agente antimicrobiano de fosfônio. em uma modalidade preferida, a presente invenção refere-se a uma composição óptica, nasal ou oftálmica (por exemplo, uma solução aquosa oftálmica), que inclui um composto de sal de fosfônio como um agente antimicrobina. as composições tipicamente possuem atividades antimicrobiana suficiente para satisfazer os requisitos de eficácia de conservação da usp e/ou padrões de conservação semelhantes (por exemplo, ep e jp).
BR112012027432A 2010-04-28 2011-04-26 composições farmacêuticas com agentes antimicrobianos de fosfônio BR112012027432A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32881510P 2010-04-28 2010-04-28
PCT/US2011/033857 WO2011137090A1 (en) 2010-04-28 2011-04-26 Pharmaceutical compositions with phosphonium antimicrobial agents

Publications (1)

Publication Number Publication Date
BR112012027432A2 true BR112012027432A2 (pt) 2016-08-09

Family

ID=44123163

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012027432A BR112012027432A2 (pt) 2010-04-28 2011-04-26 composições farmacêuticas com agentes antimicrobianos de fosfônio

Country Status (15)

Country Link
US (2) US20110269719A1 (pt)
EP (1) EP2563375B1 (pt)
JP (2) JP2013525439A (pt)
KR (1) KR20130093468A (pt)
CN (1) CN102858352B (pt)
AU (1) AU2011245442B2 (pt)
BR (1) BR112012027432A2 (pt)
CA (1) CA2795369A1 (pt)
DK (1) DK2563375T3 (pt)
ES (1) ES2494668T3 (pt)
MX (1) MX2012012089A (pt)
PL (1) PL2563375T3 (pt)
PT (1) PT2563375E (pt)
SI (1) SI2563375T1 (pt)
WO (1) WO2011137090A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102858352B (zh) 2010-04-28 2015-05-06 爱尔康研究有限公司 含有鏻抗微生物剂的药物组合物
EP3955935A4 (en) * 2019-04-16 2023-01-18 Lunella Biotech, Inc. ALKYL-TPP COMPOUNDS FOR MITOCHONDRIA TARGETING AND CANCER THERAPIES
CN110226604B (zh) * 2019-07-05 2020-08-21 中国科学院南京土壤研究所 一种磁性生物质炭-季鏻盐杀菌材料、制备及使用方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3281365A (en) 1963-12-23 1966-10-25 Monsanto Co Antiseptic detergent compositions
US3294632A (en) * 1964-08-31 1966-12-27 Hooker Chemical Corp Controlling bacteria on textile materials with reaction products of tetrakis (alpha-hydroxyorgano) phosphonium halides combined with formaldehyde source materials
US3998754A (en) 1974-07-31 1976-12-21 Exxon Research And Engineering Company Surface active quaternary higher dialkyl phosphonium salts
US4188380A (en) 1974-07-31 1980-02-12 Exxon Research & Engineering Co. Surface active quaternary higher dialkyl phosphonium salt biocides and intermediates
EP0066544B1 (de) 1981-05-30 1985-01-09 Ciba-Geigy Ag Wasseraufbereitung
EP0139404B1 (en) 1983-08-26 1988-02-03 Albright & Wilson Limited Biocidal water treatment
DE3628801A1 (de) * 1986-08-25 1988-03-03 Henkel Kgaa Antimikrobiell wirksame gemische
US5366727A (en) * 1991-02-21 1994-11-22 Nippon Chemical Industrial Co., Ltd. Antibacterial agent
DE69413790T2 (de) 1993-07-14 1999-02-25 Nippon Chemical Industrial Co., Ltd., Tokio/Tokyo Antibakterielles polymer, kontaktlinse und kontaktlinsenpflegeprodukt
DE69524953T2 (de) * 1994-05-20 2002-08-29 Novavax, Inc. Antibakterielle öl-in-wasser-emulsion
AU686818B2 (en) 1994-05-25 1998-02-12 John Mcmichael Materials and methods for treatment of plaquing diseases
JPH11147918A (ja) * 1997-11-14 1999-06-02 Menicon Co Ltd 水可溶性抗菌ポリマーおよびそれからなるコンタクトレンズ用液剤
JPH11271695A (ja) 1998-03-25 1999-10-08 Menicon Co Ltd コンタクトレンズ用液剤
JP4268703B2 (ja) * 1998-08-03 2009-05-27 株式会社メニコン コンタクトレンズ用流通保存液およびそれを用いたコンタクトレンズの流通保存方法
CA2308896A1 (en) 2000-05-18 2001-11-18 Allan James Robertson Phosphonium salts
JP2003137712A (ja) * 2001-11-02 2003-05-14 Hakuto Co Ltd デンプン配合組成物の腐敗抑制方法
US6939554B2 (en) * 2002-02-05 2005-09-06 Michigan Biotechnology Institute Antimicrobial polymer
US6579859B1 (en) * 2002-06-10 2003-06-17 Ge Betz, Inc. Control of protozoa and protozoan cysts that harbor legionella
US7125967B2 (en) * 2003-10-08 2006-10-24 Adjuvant Pharmaceuticals, Llc Water-soluble chitosan having low endotoxin concentration and methods for making and using the same
GB0403773D0 (en) * 2004-02-20 2004-03-24 Rhodia Consumer Specialities L Embedded biocide
CN100443580C (zh) * 2006-03-21 2008-12-17 侯丽君 隐形眼镜清洗液组合物及其用途
UA106606C2 (uk) * 2009-03-16 2014-09-25 Родія Оперейшнс Стабілізована біоцидна композиція
CN102858352B (zh) 2010-04-28 2015-05-06 爱尔康研究有限公司 含有鏻抗微生物剂的药物组合物

Also Published As

Publication number Publication date
EP2563375A1 (en) 2013-03-06
CN102858352B (zh) 2015-05-06
SI2563375T1 (sl) 2014-09-30
AU2011245442B2 (en) 2015-01-22
US20110269719A1 (en) 2011-11-03
MX2012012089A (es) 2012-11-29
AU2011245442A1 (en) 2012-10-25
PT2563375E (pt) 2014-09-02
ES2494668T3 (es) 2014-09-15
EP2563375B1 (en) 2014-06-25
JP2013525439A (ja) 2013-06-20
US20140080793A1 (en) 2014-03-20
WO2011137090A1 (en) 2011-11-03
PL2563375T3 (pl) 2014-11-28
DK2563375T3 (da) 2014-08-18
CA2795369A1 (en) 2011-11-03
US9694021B2 (en) 2017-07-04
CN102858352A (zh) 2013-01-02
KR20130093468A (ko) 2013-08-22
JP2016041773A (ja) 2016-03-31

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law
B06F Objections, documents and/or translations needed after an examination request according art. 34 industrial property law
B07E Notice of approval relating to section 229 industrial property law

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B08F Application fees: dismissal - article 86 of industrial property law

Free format text: REFERENTE A 8A ANUIDADE.

B08K Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87)

Free format text: REFERENTE AO ARQUIVAMENTO PUBLICADO NA RPI 2515 DE 19/03/2019.