BR112012021350A2 - calibração de massa pulsada em espectrometria de massa de duração de trajeto. - Google Patents

calibração de massa pulsada em espectrometria de massa de duração de trajeto.

Info

Publication number
BR112012021350A2
BR112012021350A2 BR112012021350A BR112012021350A BR112012021350A2 BR 112012021350 A2 BR112012021350 A2 BR 112012021350A2 BR 112012021350 A BR112012021350 A BR 112012021350A BR 112012021350 A BR112012021350 A BR 112012021350A BR 112012021350 A2 BR112012021350 A2 BR 112012021350A2
Authority
BR
Brazil
Prior art keywords
mass
calibration
path
sample
pulsed
Prior art date
Application number
BR112012021350A
Other languages
English (en)
Other versions
BR112012021350B1 (pt
Inventor
Edward B Ledford Jr
Original Assignee
Zoex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zoex Corp filed Critical Zoex Corp
Publication of BR112012021350A2 publication Critical patent/BR112012021350A2/pt
Publication of BR112012021350B1 publication Critical patent/BR112012021350B1/pt

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0009—Calibration of the apparatus
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/40—Time-of-flight spectrometers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)

Abstract

calibração de massa pulsada em espectrometria de massa de duração de trajeto. é oferecido um método para calibração de medições de relação massa-carga obtidas por um espectrômetro de massa de duração de trajeto usado como detector de um sistema de cromatografia. o método pode incluir a apresentação de um material de calibração ao espectrômetro de massa de duração de trajetória depois que uma amostra for colocada no sistema cromatográfico, mas antes da análise da amostra estar completa, de modo que o material de calibração e a mostra de 20 cm de materiall não estejam presentes na fonte de íons do espectrômetro de massa continuamente. o método pode incluir a obtenção de vários espectros de massa do material de calibração durante uma série analítica, e em algumas configurações, o cálculo de várias calibrações de massa com base nos espectros de massa obtidos a partir do material de calibração introduzido durante a série analítica.
BR112012021350-4A 2010-02-26 2011-02-25 Calibração de massa pulsada em espectrometria de massa de duração de trajeto BR112012021350B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30851910P 2010-02-26 2010-02-26
US61/308,519 2010-02-26
PCT/US2011/026239 WO2011106640A2 (en) 2010-02-26 2011-02-25 Pulsed mass calibration in time-of-flight mass spectrometry

Publications (2)

Publication Number Publication Date
BR112012021350A2 true BR112012021350A2 (pt) 2016-10-25
BR112012021350B1 BR112012021350B1 (pt) 2020-10-06

Family

ID=44507585

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012021350-4A BR112012021350B1 (pt) 2010-02-26 2011-02-25 Calibração de massa pulsada em espectrometria de massa de duração de trajeto

Country Status (6)

Country Link
US (2) US8829430B2 (pt)
EP (1) EP2539919B1 (pt)
JP (1) JP5421468B2 (pt)
CN (1) CN103262204B (pt)
BR (1) BR112012021350B1 (pt)
WO (1) WO2011106640A2 (pt)

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US8829430B2 (en) * 2010-02-26 2014-09-09 Zoex Corporation Pulsed mass calibration in time-of-flight mass spectrometry
EP2600146A1 (de) 2011-12-01 2013-06-05 EADS Deutschland GmbH Probenträger mit Kalibriersubstanz
CN103163209B (zh) * 2011-12-19 2014-12-10 中国科学院大连化学物理研究所 一种气体样品在线连续监测的质谱方法
EP2741312A1 (en) 2012-12-05 2014-06-11 Tofwerk AG Method of calibrating mass-to-charge ratio measurements obtained from a mass spectrometer connected in fluid communication with an analysis system delivering a temporally changing sample
EP2965343B1 (en) * 2013-03-06 2019-08-07 Micromass UK Limited Improved lock component corrections
US9728383B2 (en) 2013-06-07 2017-08-08 Micromass Uk Limited Method of calibrating ion signals
GB201408593D0 (en) * 2014-05-14 2014-06-25 Smiths Detection Watford Ltd Chemical calibration process, system and device
WO2015181562A1 (en) * 2014-05-29 2015-12-03 Micromass Uk Limited Monitoring liquid chromatography elution to determine when to perform a lockmass calibration
US9741548B2 (en) 2014-07-03 2017-08-22 Shimadzu Corporation Mass spectrometer
CN106024571B (zh) 2015-03-25 2018-08-24 萨默费尼根有限公司 用于质量校准的系统和方法
US10890562B2 (en) * 2015-10-07 2021-01-12 Shimadzu Corporation Tandem mass spectrometer
GB2552841B (en) * 2016-08-12 2020-05-20 Thermo Fisher Scient Bremen Gmbh Method of calibrating a mass spectrometer
US10707063B2 (en) * 2016-12-22 2020-07-07 Rapiscan Systems, Inc. Systems and methods for calibration, verification, and sensitivity checks for detectors
GB201808949D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Bench-top time of flight mass spectrometer
GB201808912D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Bench-top time of flight mass spectrometer
GB201808893D0 (en) * 2018-05-31 2018-07-18 Micromass Ltd Bench-top time of flight mass spectrometer
GB2576077B (en) 2018-05-31 2021-12-01 Micromass Ltd Mass spectrometer
US10600626B1 (en) 2018-12-14 2020-03-24 Thermos Finnigan Llc Mass calibration device for a mass spectrometer
CN111508813B (zh) * 2019-01-30 2023-09-01 广州禾信仪器股份有限公司 飞行时间质谱仪的自动校正方法、装置以及存储介质
GB2581211B (en) * 2019-02-11 2022-05-25 Thermo Fisher Scient Bremen Gmbh Mass calibration of mass spectrometer
US11764049B2 (en) * 2020-04-14 2023-09-19 Waters Technologies Corporation Coaxial introduction of calibrant in a flow path with analyte to an ion source
JP7390270B2 (ja) 2020-09-11 2023-12-01 日本電子株式会社 質量分析システム及び変換式補正方法
EP4006952A1 (en) * 2020-11-25 2022-06-01 F. Hoffmann-La Roche AG Anomaly detection of gas flow parameters in mass spectrometry

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US20070200060A1 (en) * 2006-02-28 2007-08-30 Russ Charles W Iv Pulsed internal lock mass for axis calibration
US20080067356A1 (en) * 2006-09-20 2008-03-20 Goodley Paul C Ionization of neutral gas-phase molecules and mass calibrants
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US8829430B2 (en) * 2010-02-26 2014-09-09 Zoex Corporation Pulsed mass calibration in time-of-flight mass spectrometry

Also Published As

Publication number Publication date
EP2539919A4 (en) 2015-03-11
CN103262204A (zh) 2013-08-21
JP5421468B2 (ja) 2014-02-19
EP2539919B1 (en) 2018-07-11
JP2013521470A (ja) 2013-06-10
WO2011106640A4 (en) 2012-02-02
CN103262204B (zh) 2016-04-06
US20130075598A1 (en) 2013-03-28
EP2539919A2 (en) 2013-01-02
BR112012021350B1 (pt) 2020-10-06
WO2011106640A2 (en) 2011-09-01
US20150008310A1 (en) 2015-01-08
US8829430B2 (en) 2014-09-09
WO2011106640A3 (en) 2011-12-22

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Legal Events

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B15I Others concerning applications: loss of priority

Free format text: PERDA DA PRIORIDADE US 61/308,519 DE 26/02/2010, CONFORME AS DISPOSICOES PREVISTAS NA LEI 9.279 DE 14/05/1996 (LPI) ART. 16 7O E NO ART. 29 DA RESOLUCAO INPI-PR 77/2013, POR NAO ATENDER AO DISPOSTO NA LEI 9.279 DE 14/05/1996 (LPI) ART. 16 6O E NO ART. 28 DA RESOLUCAO INPI-PR 77/2013, POIS NAO FOI APRESENTADA CESSAO DA REFERIDA PRIORIDADE, QUE POSSUI DEPOSITANTE DIFERENTE DO DEPOSITANTE DA FASE NACIONAL.

B12F Appeal: other appeals
B06F Objections, documents and/or translations needed after an examination request according art. 34 industrial property law
B06U Preliminary requirement: requests with searches performed by other patent offices: suspension of the patent application procedure
B09A Decision: intention to grant
B16A Patent or certificate of addition of invention granted

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 25/02/2011, OBSERVADAS AS CONDICOES LEGAIS.