BR112012016575A2 - composição para cuidado da pele/dermatológica, fator de crescimento heterólogo produzido por planta, e, método para fabricar um produto tópico - Google Patents
composição para cuidado da pele/dermatológica, fator de crescimento heterólogo produzido por planta, e, método para fabricar um produto tópicoInfo
- Publication number
- BR112012016575A2 BR112012016575A2 BR112012016575A BR112012016575A BR112012016575A2 BR 112012016575 A2 BR112012016575 A2 BR 112012016575A2 BR 112012016575 A BR112012016575 A BR 112012016575A BR 112012016575 A BR112012016575 A BR 112012016575A BR 112012016575 A2 BR112012016575 A2 BR 112012016575A2
- Authority
- BR
- Brazil
- Prior art keywords
- growth factor
- dermatological
- skin care
- plant
- composition
- Prior art date
Links
- 239000003102 growth factor Substances 0.000 title abstract 8
- 239000000203 mixture Substances 0.000 title abstract 8
- 238000000034 method Methods 0.000 title abstract 2
- 229940025703 topical product Drugs 0.000 title abstract 2
- 239000002537 cosmetic Substances 0.000 abstract 3
- 230000009261 transgenic effect Effects 0.000 abstract 3
- 241001465754 Metazoa Species 0.000 abstract 2
- 230000000699 topical effect Effects 0.000 abstract 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000000356 contaminant Substances 0.000 abstract 1
- 239000007857 degradation product Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000000284 extract Substances 0.000 abstract 1
- 229920002674 hyaluronan Polymers 0.000 abstract 1
- 229960003160 hyaluronic acid Drugs 0.000 abstract 1
- 239000000419 plant extract Substances 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2006—IL-1
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/168—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1808—Epidermal growth factor [EGF] urogastrone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1841—Transforming growth factor [TGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1858—Platelet-derived growth factor [PDGF]
- A61K38/1866—Vascular endothelial growth factor [VEGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Birds (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Vascular Medicine (AREA)
- Cell Biology (AREA)
- Botany (AREA)
- Physics & Mathematics (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"composição para cuidado da pele/dermatológica, fator de crescimento heterólogo produzido por planta,e, método para fabricar um produto tópico". são fornecidoas composições cosméticas e dermatológicas para cuidado da pele que contêm um extrato de planta transgênica contendo um fator de crescimento, ou um fator de crescimento purificado a partir de plantas transgênicas, ou uma mistura de fatores de crescimento derivados de plantas transgênicas como extratos ou na forma purificada, para uso em produtos terapêuticos tópicos, dermatologia e cosméticos. de maneira importante, esta invenção fornece fatores de crescimento estabilizados e seguros disponíveis para uso no tratamento cosmético e tópico. a composição preferida compreende um fator de crescimento produzido por planta e ácido hialurônico. as composições para cuidado da pele/ddermatológicas com fator de crescimento estabilizado não apresentam o risco de produtos de degradação indesejados e a resultante perda da atividade da composição. além do mais, a composição não apresenta contaminantes e agentes transmissíveis, que podem resultar de animais ou de sistemas de expressão a base de célula animal ou bacteriana.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IS8871 | 2010-01-06 | ||
PCT/IS2011/050001 WO2011083500A2 (en) | 2010-01-06 | 2011-01-06 | Method of use of stabilized plant-derived growth factor in skin care |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112012016575A2 true BR112012016575A2 (pt) | 2016-04-12 |
Family
ID=44071001
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112012016575A BR112012016575A2 (pt) | 2010-01-06 | 2011-01-06 | composição para cuidado da pele/dermatológica, fator de crescimento heterólogo produzido por planta, e, método para fabricar um produto tópico |
Country Status (11)
Country | Link |
---|---|
US (1) | US20130266536A1 (pt) |
EP (1) | EP2521532A2 (pt) |
JP (1) | JP2013516460A (pt) |
KR (1) | KR20120115535A (pt) |
CN (1) | CN102811704A (pt) |
AU (1) | AU2011204391A1 (pt) |
BR (1) | BR112012016575A2 (pt) |
CA (1) | CA2785631A1 (pt) |
RU (1) | RU2012133444A (pt) |
SG (1) | SG181969A1 (pt) |
WO (1) | WO2011083500A2 (pt) |
Families Citing this family (24)
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WO2013005234A1 (en) * | 2011-07-06 | 2013-01-10 | Orf Liftaekni Hf | Therapeutic use of stabilised factor for dermatological conditions |
WO2013005235A1 (en) * | 2011-07-06 | 2013-01-10 | Orf Liftaekni Hf | Method of use of stabilised non-plant-derived growth factor in skin care |
CN102988200B (zh) * | 2012-12-10 | 2014-09-17 | 北京莱米瑞克科技发展有限公司 | 脂质体养颜护肤品 |
KR20150133222A (ko) * | 2013-03-13 | 2015-11-27 | 스테메트릭스, 인코포레이티드. | 피부 조성물 및 피부 조성물의 용도 |
KR101645234B1 (ko) * | 2014-02-03 | 2016-08-03 | 경북대학교 산학협력단 | 신규한 극지 미생물 유래 디하이드린 유전자 및 그 용도 |
CN103908424A (zh) * | 2014-03-03 | 2014-07-09 | 奥思达干细胞有限公司 | 一种用于美容保养的精华液及其制备方法 |
KR101629504B1 (ko) * | 2014-04-14 | 2016-06-10 | 주식회사 엘지생활건강 | 사이토카인 조합을 함유하는 피부 상태 개선용 조성물 |
CN103908416A (zh) * | 2014-04-22 | 2014-07-09 | 黄忠亨 | 一种护肤活性因子组合物 |
CN104027836A (zh) * | 2014-06-24 | 2014-09-10 | 南京仁天生物科技有限公司 | 一种与皮肤协同作用的敷料及其制备和应用 |
TW201636045A (zh) * | 2015-01-28 | 2016-10-16 | 波美西恩製藥有限責任公司 | 組成物、促進或增強受試者之局部毛髮飽滿度及厚度或毛髮生長之方法、包括該組成物之套組及裝置 |
JP2016172707A (ja) * | 2015-03-18 | 2016-09-29 | 株式会社UniBio | 植物体内で発現させた上皮細胞増殖因子の精製品の製造方法 |
US10278914B2 (en) | 2015-08-13 | 2019-05-07 | Coty Inc. | Formulation and method for promoting cutaneous uptake of molecular oxygen by skin |
CN105055285B (zh) * | 2015-08-26 | 2018-01-19 | 浙江奥瑞健生物技术有限公司 | 一种皮肤营养液及其制备方法 |
FR3052668B1 (fr) * | 2016-06-16 | 2018-06-01 | Pierre Fabre Dermo-Cosmetique | Extrait de cellules indifferenciees de mimosa pudica et ses utilisations en dermo cosmetique |
WO2018015973A1 (en) * | 2016-07-21 | 2018-01-25 | Khorakiwala Habil F | Topical pharmaceutical composition for promoting hair growth and/or reducing hair loss |
KR102661225B1 (ko) * | 2016-09-08 | 2024-04-29 | 주식회사 엘지생활건강 | 세포 성장인자 안정화 성분을 함유하는 화장료 조성물 |
CN106389290A (zh) * | 2016-11-14 | 2017-02-15 | 天津贝罗尼生物科技有限公司 | 一种含pdgf的祛疤膏及其制备方法 |
CN109260457B (zh) * | 2017-07-18 | 2023-06-13 | 苏州高泓利康生物科技有限公司 | 一种透明质酸-白介素10复合物、其制备方法及其应用 |
KR101951283B1 (ko) * | 2017-11-13 | 2019-02-22 | 양미경 | 탈모의 예방 또는 치료용, 또는 발모 또는 육모 촉진용 약학 또는 화장료 조성물 |
KR101924894B1 (ko) * | 2018-07-25 | 2018-12-04 | 베네브바이오랩 주식회사 | 소음순 피부 치료용 피부연고 |
KR102140531B1 (ko) * | 2018-08-07 | 2020-08-04 | (주)휴온스 | Gly-Tβ4의 제조방법 |
EP4120996A1 (en) * | 2020-03-19 | 2023-01-25 | Skingen International Inc. | Skin care compositions comprising 8 or more recombinant human growth factors and use thereof for reducing sings of aging |
AU2021284721A1 (en) * | 2020-06-05 | 2023-02-02 | Orf Liftaekni Hf. | Growth factor composition for cell culture-produced meat |
CN116889545B (zh) * | 2023-06-27 | 2023-12-29 | 上海腾瑞制药股份有限公司 | 一种重组人酸性成纤维细胞生长因子凝胶剂及其制备工艺 |
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WO2005021764A2 (en) | 2003-08-27 | 2005-03-10 | Orf Liftaekni Hf. | A process for proteolytic cleavage and purification of recombinant proteins produced in plants |
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WO2008031196A1 (en) * | 2006-09-13 | 2008-03-20 | Enhance Skin Products, Inc. | Treatment of aged skin with autologous growth factors in a hyaluronic acid delivery system |
-
2011
- 2011-01-06 BR BR112012016575A patent/BR112012016575A2/pt not_active Application Discontinuation
- 2011-01-06 WO PCT/IS2011/050001 patent/WO2011083500A2/en active Application Filing
- 2011-01-06 US US13/520,964 patent/US20130266536A1/en not_active Abandoned
- 2011-01-06 JP JP2012547591A patent/JP2013516460A/ja active Pending
- 2011-01-06 SG SG2012047759A patent/SG181969A1/en unknown
- 2011-01-06 RU RU2012133444/15A patent/RU2012133444A/ru unknown
- 2011-01-06 CA CA2785631A patent/CA2785631A1/en not_active Abandoned
- 2011-01-06 EP EP11702713A patent/EP2521532A2/en not_active Withdrawn
- 2011-01-06 KR KR1020127020435A patent/KR20120115535A/ko not_active Application Discontinuation
- 2011-01-06 CN CN2011800055244A patent/CN102811704A/zh active Pending
- 2011-01-06 AU AU2011204391A patent/AU2011204391A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20130266536A1 (en) | 2013-10-10 |
EP2521532A2 (en) | 2012-11-14 |
WO2011083500A2 (en) | 2011-07-14 |
CA2785631A1 (en) | 2011-07-14 |
CN102811704A (zh) | 2012-12-05 |
KR20120115535A (ko) | 2012-10-18 |
RU2012133444A (ru) | 2014-02-20 |
SG181969A1 (en) | 2012-08-30 |
AU2011204391A1 (en) | 2012-08-16 |
JP2013516460A (ja) | 2013-05-13 |
WO2011083500A3 (en) | 2011-12-08 |
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