BR112012006486A2 - processo de detecção de pelo menos uma molécula alvo em uma amostra por espectrometria de massa. - Google Patents

processo de detecção de pelo menos uma molécula alvo em uma amostra por espectrometria de massa.

Info

Publication number
BR112012006486A2
BR112012006486A2 BR112012006486A BR112012006486A BR112012006486A2 BR 112012006486 A2 BR112012006486 A2 BR 112012006486A2 BR 112012006486 A BR112012006486 A BR 112012006486A BR 112012006486 A BR112012006486 A BR 112012006486A BR 112012006486 A2 BR112012006486 A2 BR 112012006486A2
Authority
BR
Brazil
Prior art keywords
target molecule
sample
detecting
mass spectrometry
ions
Prior art date
Application number
BR112012006486A
Other languages
English (en)
Portuguese (pt)
Inventor
Arnaud Salvador
Jean-Philippe Charrier
Jérôme Lemoine
Philippe Dugourd
Tanguy Fortin
Original Assignee
Biomérieux; Universite Claude Bernard Lyon I E Ct Nat De La Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomérieux; Universite Claude Bernard Lyon I E Ct Nat De La Rech Scient filed Critical Biomérieux; Universite Claude Bernard Lyon I E Ct Nat De La Rech Scient
Publication of BR112012006486A2 publication Critical patent/BR112012006486A2/pt

Links

Classifications

    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/26Mass spectrometers or separator tubes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/0027Methods for using particle spectrometers
    • H01J49/0031Step by step routines describing the use of the apparatus
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/26Mass spectrometers or separator tubes
    • H01J49/34Dynamic spectrometers
    • H01J49/42Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/26Mass spectrometers or separator tubes
    • H01J49/34Dynamic spectrometers
    • H01J49/42Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/426Methods for controlling ions
    • H01J49/427Ejection and selection methods

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
BR112012006486A 2009-09-25 2010-09-15 processo de detecção de pelo menos uma molécula alvo em uma amostra por espectrometria de massa. BR112012006486A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0956662A FR2950697B1 (fr) 2009-09-25 2009-09-25 Procede de detection de molecules par spectrometrie de masse
PCT/FR2010/051919 WO2011036378A1 (fr) 2009-09-25 2010-09-15 Procede de detection de molecules par spectrometrie de masse

Publications (1)

Publication Number Publication Date
BR112012006486A2 true BR112012006486A2 (pt) 2016-11-22

Family

ID=42105918

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012006486A BR112012006486A2 (pt) 2009-09-25 2010-09-15 processo de detecção de pelo menos uma molécula alvo em uma amostra por espectrometria de massa.

Country Status (11)

Country Link
US (1) US9018580B2 (enExample)
EP (1) EP2481078B1 (enExample)
JP (1) JP5730878B2 (enExample)
KR (1) KR20130004561A (enExample)
CN (1) CN102598204A (enExample)
BR (1) BR112012006486A2 (enExample)
FR (1) FR2950697B1 (enExample)
IN (1) IN2012DN02538A (enExample)
MX (1) MX2012003626A (enExample)
RU (1) RU2012113416A (enExample)
WO (1) WO2011036378A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3156496B1 (fr) * 2011-04-21 2019-04-10 Biomérieux Inc. Procede de detection d'au moins un mecanisme de resistance aux cephalosporines par spectrometrie de masse
EP3087581A4 (en) * 2013-12-23 2017-07-26 DH Technologies Development PTE. Ltd. Mass spectrometer
EP3259594A4 (en) * 2015-02-20 2018-12-26 The Johns Hopkins University Biomarkers of myocardial injury
JPWO2016147839A1 (ja) * 2015-03-17 2017-12-28 アサヒビール株式会社 ハイドロフォビンの定量方法及び発泡麦芽飲料の噴き性予測方法
JP6473366B2 (ja) * 2015-03-31 2019-02-20 シスメックス株式会社 温度判定方法、標的ペプチドの検出方法および温度判定試薬
KR102062149B1 (ko) * 2015-05-22 2020-01-03 익스프레션 패톨로지, 인크. 사이클린-의존성 키나제 억제제 2A(p16) 단백질에 대한 SRM/MRM 분석법
EP3334508B1 (en) 2015-08-13 2024-12-18 Waters Technologies Corporation Alloy material devices and components
CN108351333B (zh) * 2015-10-28 2020-10-30 株式会社岛津制作所 气相色谱仪及试样注入方法
EP3491374B1 (en) 2016-07-28 2024-10-09 Waters Technologies Corporation Encapsulated pre-analytic workflow reagents for flow-through devices, liquid chromatography and mass spectrometric analysis
EP3373324A1 (en) * 2017-03-10 2018-09-12 Thermo Finnigan LLC Methods and systems for quantitative mass analysis
GB201802917D0 (en) 2018-02-22 2018-04-11 Micromass Ltd Charge detection mass spectrometry
US11984311B2 (en) * 2018-10-10 2024-05-14 Purdue Research Foundation Mass spectrometry via frequency tagging
WO2021207494A1 (en) 2020-04-09 2021-10-14 Waters Technologies Corporation Ion detector
US11232936B2 (en) * 2020-05-28 2022-01-25 Thermo Finnigan Llc Absolute quantitation of a target analyte using a mass spectrometer
CN118402037A (zh) 2021-12-15 2024-07-26 水技术公司 具有集成放大器的感应式检测器
KR102625713B1 (ko) 2021-12-16 2024-01-17 한국전자기술연구원 스마트 안전바 시스템

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5171991A (en) * 1991-01-25 1992-12-15 Finnigan Corporation Quadrupole ion trap mass spectrometer having two axial modulation excitation input frequencies and method of parent and neutral loss scanning
US5200613A (en) * 1991-02-28 1993-04-06 Teledyne Mec Mass spectrometry method using supplemental AC voltage signals
CA2240325A1 (en) * 1998-03-27 1998-11-14 Synsorb Biotech, Inc. Methods for screening compound libraries
GB2389704B (en) * 2002-05-17 2004-06-02 * Micromass Limited Mass Spectrometer
US20070269895A1 (en) 2002-06-03 2007-11-22 The Institute For Systems Biology Methods for quantitative proteome analysis of glycoproteins
US7501286B2 (en) 2002-08-14 2009-03-10 President And Fellows Of Harvard College Absolute quantification of proteins and modified forms thereof by multistage mass spectrometry
US7632686B2 (en) 2002-10-03 2009-12-15 Anderson Forschung Group High sensitivity quantitation of peptides by mass spectrometry
US7473892B2 (en) * 2003-08-13 2009-01-06 Hitachi High-Technologies Corporation Mass spectrometer system
JP4515819B2 (ja) * 2003-08-13 2010-08-04 株式会社日立ハイテクノロジーズ 質量分析システム
US6958473B2 (en) * 2004-03-25 2005-10-25 Predicant Biosciences, Inc. A-priori biomarker knowledge based mass filtering for enhanced biomarker detection
EP1749896A4 (en) 2004-04-08 2009-06-24 Tohoku Techno Arch Co Ltd PROCESS FOR ATOMIZING ALLOY CRYSTAL GRAIN BY HYDROGEN TREATMENT
JP4300154B2 (ja) 2004-05-14 2009-07-22 株式会社日立ハイテクノロジーズ イオントラップ/飛行時間質量分析計およびイオンの精密質量測定方法
JP2006300758A (ja) * 2005-04-21 2006-11-02 Apro Life Science Institute Inc 内部標準ペプチドを用いて生体由来試料に含まれる標的タンパク質を定量する方法
EP1736480B9 (en) 2005-06-02 2009-03-04 Polyquant GmbH Artificial protein, method for absolute quantification of proteins and uses thereof
GB0511386D0 (en) * 2005-06-03 2005-07-13 Shimadzu Res Lab Europe Ltd Method for introducing ions into an ion trap and an ion storage apparatus
GB0524042D0 (en) * 2005-11-25 2006-01-04 Micromass Ltd Mass spectrometer
JP5259169B2 (ja) * 2007-01-10 2013-08-07 日本電子株式会社 タンデム型飛行時間型質量分析装置および方法
GB0701476D0 (en) * 2007-01-25 2007-03-07 Micromass Ltd Mass spectrometer
GB0703378D0 (en) * 2007-02-21 2007-03-28 Micromass Ltd Mass spectrometer
WO2008146100A1 (en) 2007-06-01 2008-12-04 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for absolute quantification of polypeptides
GB0717146D0 (en) * 2007-09-04 2007-10-17 Micromass Ltd Mass spectrometer
US8399827B1 (en) * 2007-09-10 2013-03-19 Cedars-Sinai Medical Center Mass spectrometry systems
GB2463633B (en) * 2008-05-15 2013-02-27 Thermo Fisher Scient Bremen MS/MS data processing
JP5449701B2 (ja) * 2008-05-28 2014-03-19 株式会社日立ハイテクノロジーズ 質量分析計
WO2009146418A1 (en) * 2008-05-30 2009-12-03 Purdue Research Foundation Non-destructive, high order harmonic ion motion image current detection
GB201011862D0 (en) * 2010-07-14 2010-09-01 Thermo Fisher Scient Bremen Ion detection arrangement

Also Published As

Publication number Publication date
RU2012113416A (ru) 2013-10-27
JP2013506124A (ja) 2013-02-21
IN2012DN02538A (enExample) 2015-08-28
CN102598204A (zh) 2012-07-18
EP2481078B1 (fr) 2023-06-21
WO2011036378A1 (fr) 2011-03-31
US20120205535A1 (en) 2012-08-16
FR2950697A1 (fr) 2011-04-01
FR2950697B1 (fr) 2011-12-09
JP5730878B2 (ja) 2015-06-10
US9018580B2 (en) 2015-04-28
MX2012003626A (es) 2012-08-23
EP2481078A1 (fr) 2012-08-01
KR20130004561A (ko) 2013-01-11

Similar Documents

Publication Publication Date Title
BR112012006486A2 (pt) processo de detecção de pelo menos uma molécula alvo em uma amostra por espectrometria de massa.
BR112015005887A2 (pt) quantificação de tiroglobulina por espectroscopia de massa
CA2873099C (en) Aptamer-based multiplexed assays
WO2012092281A3 (en) Quantitation of insulin by mass spectrometry
BR112017025097A2 (pt) método para quantificação espectrométrica de massa de analitos extraídos de um dispositivo de microamostragem
WO2008142579A3 (en) Method of mass analysis of target molecules in complex mixtures
WO2013148181A3 (en) Method and apparatus to provide parallel acquisition of mass spectrometry/mass spectrometry data
WO2007079234A3 (en) Multi-dimensional ion mobility spectrometry apparatus and methods
WO2012003478A3 (en) Detecting targets using mass tags and mass spectrometry
WO2009076139A3 (en) Thyroglobulin quantitation by mass spectrometry
BRPI0809446B8 (pt) Método de determinação da presença ou quantidade de glifosato, n-acetilglifosato, ácido n-acetilaminometifosfônico (n-acetil ampa), ou ácido de fosfônico aminometil (ampa) em uma amostra de teste e método de purificação de pelo menos glifosato, n-acetil ampa ou n-acetilglifosato do ampa
WO2007103124A3 (en) Methods for distinguishing isomers using mass spectrometry
WO2013093482A3 (en) An imaging mass spectrometer and a method of mass spectrometry
EP2086000A3 (en) Methods and Apparatus for Reducing Noise in Mass Spectrometry
GB201305639D0 (en) A method of mass spectrometry and a mass spectrometer
JP2013513802A5 (enExample)
WO2008062372A3 (en) Device for separation and maldi analysis of an analyte in a sample
WO2009113044A3 (en) Method for a highly sensitive detection and quantification of biomolecules using secondary ion mass spectrometry (sims)
WO2013184995A8 (en) Methods and apparatus for performing mass spectrometry
WO2018013678A3 (en) Molecular markers and methods for sample analysis via mass spectrometry
WO2011002146A3 (ko) 악성코드 탐지시스템 및 방법
WO2011154219A3 (en) A method computer program and system to analyze mass spectra
BRPI0605166A (pt) método de determinação de ácido metilmalÈnico baseado na extração alquilativa associada à cromatografia lìquida acoplada à espectrometria de massas
BR112022014101A2 (pt) Métodos e sistemas para detectar e quantificar um analito alvo em uma amostra por espectrometria de massa em modo de íons negativos
WO2007060437A3 (en) Mass spectrometer

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]