BR0317450A - Fluidos de diálise biocompatìveis contendo icodextrinas - Google Patents

Fluidos de diálise biocompatìveis contendo icodextrinas

Info

Publication number
BR0317450A
BR0317450A BR0317450-6A BR0317450A BR0317450A BR 0317450 A BR0317450 A BR 0317450A BR 0317450 A BR0317450 A BR 0317450A BR 0317450 A BR0317450 A BR 0317450A
Authority
BR
Brazil
Prior art keywords
glucose polymer
fluids containing
dialysis fluids
icodextrins
glucose
Prior art date
Application number
BR0317450-6A
Other languages
English (en)
Inventor
Leo Martis
Carolyn Choo
Paul Zieske
Original Assignee
Baxter Int
Baxter Healthcare Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Int, Baxter Healthcare Sa filed Critical Baxter Int
Publication of BR0317450A publication Critical patent/BR0317450A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/724—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/718—Starch or degraded starch, e.g. amylose, amylopectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/28—Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
    • A61M1/287—Dialysates therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • External Artificial Organs (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

"FLUIDOS DE DIáLISE BIOCOMPATìVEIS CONTENDO ICODEXTRINAS". Soluções à base de polímero de glicose e processos de produção das mesmas, que podem ser usados durante terapia médica, tal como terapia de diálise, são proporcionados. A solução à base de polímero de glicose inclui, de preferência, uma primeira solução contendo icodextrina, a um pH variando de cerca de 1,5 a cerca de 5,0, e uma solução tampão, a um pH variando de cerca de 7,0 a cerca de 12,0, que são construídas e dispostas de modo a permitir que a solução à base de polímero de glicose seja misturada antes da infusão em um paciente. As soluções à base de polímero de glicose da presente invenção podem ser produzidas a um pH fisiológico e com um mínimo de produtos de degradação de glicose.
BR0317450-6A 2002-12-20 2003-12-18 Fluidos de diálise biocompatìveis contendo icodextrinas BR0317450A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/327,264 US20040121982A1 (en) 2002-12-20 2002-12-20 Biocompatible dialysis fluids containing icodextrins
PCT/US2003/040336 WO2004058277A1 (en) 2002-12-20 2003-12-18 Biocompatible dialysis fluids containing icodextrins

Publications (1)

Publication Number Publication Date
BR0317450A true BR0317450A (pt) 2005-11-16

Family

ID=32594208

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0317450-6A BR0317450A (pt) 2002-12-20 2003-12-18 Fluidos de diálise biocompatìveis contendo icodextrinas

Country Status (15)

Country Link
US (2) US20040121982A1 (pt)
EP (1) EP1585531B1 (pt)
JP (5) JP4719470B2 (pt)
KR (1) KR101130017B1 (pt)
CN (2) CN101843634B (pt)
AR (1) AR042795A1 (pt)
AU (1) AU2003299683B2 (pt)
BR (1) BR0317450A (pt)
CA (1) CA2510788A1 (pt)
ES (1) ES2755946T3 (pt)
HK (1) HK1088535A1 (pt)
MX (1) MXPA05006634A (pt)
SG (1) SG169228A1 (pt)
TW (1) TWI309569B (pt)
WO (1) WO2004058277A1 (pt)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050245612A1 (en) 2004-05-03 2005-11-03 Blass John P Pharmaceutical compositions for metabolic insufficiencies
US20040121982A1 (en) * 2002-12-20 2004-06-24 Leo Martis Biocompatible dialysis fluids containing icodextrins
GB0325292D0 (en) * 2003-10-29 2003-12-03 Wivenhoe Technology Ltd Treatment of sugar solutions
US7118857B2 (en) 2004-02-27 2006-10-10 Baxter International Inc. Methods and compositions for detection of microbial contaminants in peritoneal dialysis solutions
US20050276868A1 (en) * 2004-06-10 2005-12-15 Bart Degreve Bicarbonate-based peritoneal dialysis solutions
US8202248B2 (en) 2004-08-18 2012-06-19 Sequana Medical Ag Dialysis implant and methods of use
US7935070B2 (en) * 2005-01-28 2011-05-03 Fresenius Medical Care North America Systems and methods for dextrose containing peritoneal dialysis (PD) solutions with neutral pH and reduced glucose degradation product
CA2623843A1 (en) * 2005-09-29 2007-04-12 Alcon, Inc. Dual-chamber solution packaging system
US8740034B2 (en) 2010-09-30 2014-06-03 Ethicon Endo-Surgery, Inc. Surgical stapling instrument with interchangeable staple cartridge arrangements
US9585810B2 (en) 2010-10-14 2017-03-07 Fresenius Medical Care Holdings, Inc. Systems and methods for delivery of peritoneal dialysis (PD) solutions with integrated inter-chamber diffuser
WO2012129017A1 (en) * 2011-03-18 2012-09-27 Baxter International Inc. Peritoneal dialysis solutions comprising glucose polymers
USD699343S1 (en) 2011-12-20 2014-02-11 Alcon Research, Ltd. Irrigation solution bag
EP2609918A1 (en) * 2011-12-27 2013-07-03 Zytoprotec GmbH Peritoneal dialysis fluid comprising a GSK-3 inhibitor
US8585635B2 (en) 2012-02-15 2013-11-19 Sequana Medical Ag Systems and methods for treating chronic liver failure based on peritoneal dialysis
WO2014083612A1 (ja) * 2012-11-27 2014-06-05 テルモ株式会社 腹膜透析液
CN104619347B (zh) * 2012-11-27 2018-08-03 泰尔茂株式会社 腹膜透析液
JP6216777B2 (ja) * 2013-04-02 2017-10-18 テルモ株式会社 腹膜透析液
JP6313653B2 (ja) * 2014-05-19 2018-04-18 テルモ株式会社 腹膜透析液
JP6419615B2 (ja) * 2015-03-19 2018-11-07 テルモ株式会社 腹膜透析液
CN108601879A (zh) * 2015-05-28 2018-09-28 库克医学技术有限责任公司 腹膜透析系统和方法
CN108883221A (zh) * 2016-04-04 2018-11-23 美敦力公司 再生腹膜透析系统
AU2017246829A1 (en) * 2016-04-04 2018-11-15 Medtronic, Inc. Peritoneal dialysate fluid generation system with integrated cycler
US20180021501A1 (en) * 2016-04-04 2018-01-25 Medtronic, Inc. Peritoneal dialysate preparation and sensor system
WO2017176695A1 (en) * 2016-04-04 2017-10-12 Medtronic, Inc. Peritoneal dialysate fluid generation system
EP3470085A4 (en) * 2016-06-09 2019-05-22 Terumo Kabushiki Kaisha BIOCOMPATIBLE PERITONEAL DIALYSAT
CN107550928A (zh) * 2016-06-30 2018-01-09 华仁药业股份有限公司 一种葡萄糖聚合物腹膜透析液及其制备工艺
US10769244B2 (en) 2016-08-26 2020-09-08 Sequana Medical Nv Systems and methods for managing and analyzing data generated by an implantable device
FR3055898B1 (fr) * 2016-09-15 2018-11-02 Roquette Freres Nouveaux polymeres de glucose pour dialyse peritoneale
US20200101213A1 (en) * 2017-03-31 2020-04-02 Terumo Kabushiki Kaisha Peritoneal dialysis solution
EP3381484A1 (en) 2017-03-31 2018-10-03 Opterion Health AG Carbohydrate composition for dialysis
US11559618B2 (en) 2017-05-24 2023-01-24 Sequana Medical Nv Formulations and methods for direct sodium removal in patients having severe renal dysfunction
US10918778B2 (en) * 2017-05-24 2021-02-16 Sequana Medical Nv Direct sodium removal method, solution and apparatus to reduce fluid overload in heart failure patients
CN109528760A (zh) * 2018-11-13 2019-03-29 华仁药业股份有限公司 一种艾考糊精腹膜透析液及其制备方法
US11965763B2 (en) 2021-11-12 2024-04-23 Mozarc Medical Us Llc Determining fluid flow across rotary pump

Family Cites Families (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3993751A (en) * 1972-11-27 1976-11-23 Cybersol, Inc. Process for stabilizing therapeutic compositions and article
US3878664A (en) * 1972-11-27 1975-04-22 Cybersol Process for producing a therapeutic composition
CA1017249A (en) * 1973-12-19 1977-09-13 Chemo Drug Company Injectable electrolyte solutions
US3974034A (en) * 1975-09-12 1976-08-10 Cpc International Inc. Malto-dextrins of improved stability prepared by enzymatic hydrolysis of oxidized starch
US4182756A (en) * 1977-11-21 1980-01-08 Abbott Laboratories High calorie solutions of low molecular weight glucose polymer mixtures useful for intravenous administration
US4326955A (en) * 1979-06-14 1982-04-27 Diachem, Inc. Hemodialysis with sodium bicarbonate dialysate prepared in plural stages
US4756838A (en) * 1980-02-21 1988-07-12 Veltman Preston Leonard Preparation of dry dialysate products
US4489535A (en) * 1980-10-02 1984-12-25 Veltman Preston Leonard Materials and method for preparing dialysis solutions containing bicarbonate ions
US4339433A (en) * 1981-01-09 1982-07-13 Baxter Travenol Laboratories, Inc. Additives for peritoneal dialysis solutions
US4761237A (en) * 1981-07-10 1988-08-02 Baxter Travenol Laboratories, Inc. Peritoneal dialysis solution containing carbohydrate polymers
US4879280A (en) * 1981-09-24 1989-11-07 Fresenius Ag Dialysis solution for use in intraperitoneal dialysis
US4886789A (en) * 1983-01-12 1989-12-12 M. L. Laboratories Plc Peritoneal dialysis and compositions for use therein
US6077836A (en) * 1983-01-12 2000-06-20 Ml Laboratotries, Plc Peritoneal dialysis and compositions for use therein
US4604379A (en) * 1984-06-18 1986-08-05 Curators Of The University Of Missouri Dialysis solutions containing cross-linked gelatin
US4668400A (en) * 1984-06-22 1987-05-26 Veech Richard L Hemodialysis processes and hemodialysis solutions
US5100677A (en) * 1985-12-18 1992-03-31 Veech Richard L Fluid therapy with various organic anions
US4663166A (en) * 1984-06-22 1987-05-05 Veech Richard L Electrolyte solutions and in vivo use thereof
US6020007A (en) * 1984-06-22 2000-02-01 Btg International Limited Fluid therapy with l-lactate and/or pyruvate anions
JPS61247466A (ja) * 1985-04-25 1986-11-04 テルモ株式会社 腹膜透析用透析液
US6248726B1 (en) * 1985-06-22 2001-06-19 M L Laboratories Plc Method of peritoneal dialysis using glucose polymer solutions
US5091094A (en) * 1985-06-24 1992-02-25 Veech Richard L Hemodialysis processes & hemodialysis solutions
GB8521712D0 (en) * 1985-08-31 1985-10-02 Giltech Ltd Solution for peritoneal dialysis
EP0218900B1 (en) * 1985-09-10 1992-01-22 Research Corporation Technologies, Inc. Osmotic agents for peritoneal dialysis
US4976683A (en) * 1986-06-20 1990-12-11 Abbott Laboratories Peritoneal dialysis method
GR870129B (en) * 1987-01-27 1987-02-04 Giatzidis Ippokratis Stable bicarbonate - glycylglycine dialysate for hemodialysis and peritoneal dialysis
DE3812525C1 (pt) * 1988-04-15 1989-06-22 Fresenius Ag, 6380 Bad Homburg, De
US5092838A (en) * 1989-11-30 1992-03-03 Baxter International Inc. Histidine buffered peritoneal dialysis solution
AU627309B2 (en) * 1989-05-26 1992-08-20 Terumo Kabushiki Kaisha Preparation for blood dialysis and method for production thereof
DE3917251A1 (de) * 1989-05-26 1990-11-29 Fresenius Ag Natriumbicarbonat enthaltendes konzentrat sowie verfahren zur herstellung einer dialysierfluessigkeit
US5071558A (en) * 1989-08-11 1991-12-10 Nikkiso Co., Ltd. Sodium bicarbonate dialysate
SE505967C2 (sv) * 1990-10-15 1997-10-27 Gambro Ab Förfarande respektive anläggning för beredning av en medicinsk lösning, t ex en dialyslösning
DE4125819A1 (de) * 1991-08-03 1993-02-04 Rolf Prof Dr Med Zander Waessrige loesung und deren verwendung
SE9103395D0 (sv) * 1991-11-18 1991-11-18 Gambro Ab System med anvaendning av ensteril medicinsk loesning innehaallande glukos eller glukosliknande aemnen samt en loesning avsedd foer detta system
EP0555087B1 (en) * 1992-02-04 1998-08-05 Baxter International Inc. Peritoneal dialysis solutions containing at least one dipeptide
US5827820A (en) * 1992-04-06 1998-10-27 Baxter International Inc. Aqueous peritoneal dialysis solution
ATE139451T1 (de) * 1992-04-06 1996-07-15 Baxter Int Wässrige peritonealdialyse-lösung
US5616248A (en) * 1992-04-06 1997-04-01 Schal; Wilfried Method for the preparation of hemodialysis fluids containing bicarbonate
DE4242926C2 (de) * 1992-12-18 1994-12-15 Fresenius Ag Dialyselösung für die Peritonealdialyse
DK0636018T3 (da) * 1993-01-19 1997-12-08 Baxter Int Flerkammerbeholder
US5436232A (en) * 1994-01-07 1995-07-25 Laevosan-Gesellschaft Mbh Pharmaceutical composition for peritoneal dialysis
US6306836B1 (en) * 1994-01-21 2001-10-23 Baxter International Inc. Peritoneal dialysis solutions containing maltodextrins and amino acids
GB9411009D0 (en) * 1994-06-02 1994-07-20 Giltech Ltd Dialysis fluid
SE510030C2 (sv) * 1995-08-08 1999-04-12 Gambro Ab Förfarande för blandning av steril medicinsk lösning samt behållare för utförande av förfarandet
CA2155910C (en) * 1995-08-11 1999-12-14 George Wu Biocompatible aqueous solution for use in continuous ambulatory peritoneal dialysis
JP3623294B2 (ja) * 1995-11-28 2005-02-23 株式会社新素材総合研究所 電解質液が収容された医療用容器及びその製造方法
SE9600631D0 (sv) * 1996-02-20 1996-02-20 Gambro Ab Use of a solution comprising glucose for peritonial dialysis having reduced formation of AGE products
AR006049A1 (es) * 1996-03-01 1999-07-21 Johnson & Johnson Consumer Una emulsion de aceite en agua
DE19631124A1 (de) * 1996-08-01 1998-02-05 Fresenius Medical Care De Gmbh Verfahren zur Herstellung einer Bicarbonat enthaltenden Infusions- oder Dialysierlösung
GB9714218D0 (en) * 1997-07-04 1997-09-10 Allied Therapeutics Ltd Peritoneal dialysis fluid
WO1999009953A1 (fr) * 1997-08-22 1999-03-04 Shimizu Pharmaceutical Co., Ltd. Preparation contenant du glucose
SE510587C2 (sv) * 1997-10-07 1999-06-07 Gambro Lundia Ab Koncentrat för dialyslösning och användning därav
DE19748290B8 (de) * 1997-10-31 2009-09-03 Fresenius Medical Care Deutschland Gmbh Lösung für die Peritonealdialyse
EP0958832B1 (en) * 1998-05-21 2006-01-25 Nipro Corporation Albumin containing peritoneal dialysis fluid
EP0980685B1 (en) * 1998-06-17 2006-01-25 Nipro Corporation Use of a fluid for the manufacture of a dialysis fluid for continuous recirculating peritoneal dialysis
SE521219C2 (sv) * 1998-10-23 2003-10-14 Gambro Ab Metod och anordning för att reducera nedbrytning av värmekänsliga komponenter i medicinska substanser under värmesterilisering
DE69815113T2 (de) * 1998-12-04 2004-04-08 Lucent Technologies Inc. Fehlerverschleierung und -korrektur für Sprach-, Bild- und Videosignale
US6770148B1 (en) * 1998-12-04 2004-08-03 Baxter International Inc. Peritoneal dialysis solution containing modified icodextrins
JP4284737B2 (ja) * 1999-02-26 2009-06-24 株式会社ジェイ・エム・エス 中性腹膜透析液
DE19912850B4 (de) * 1999-03-22 2005-04-07 Fresenius Medical Care Deutschland Gmbh Lösung, insbesondere für Hämo- oder Peritonealdialyse, sowie Verfahren zu deren Herstellung
EP1165148A1 (en) * 1999-03-30 2002-01-02 Gambro Lundia AB Method and apparatus for sterilising a heat sensitive fluid
US6251437B1 (en) * 1999-07-13 2001-06-26 Minntech Corporation Liquid/powder acid concentrate for dialysate and a method of making the same
US6309673B1 (en) * 1999-09-10 2001-10-30 Baxter International Inc. Bicarbonate-based solution in two parts for peritoneal dialysis or substitution in continuous renal replacement therapy
US20030202958A1 (en) * 1999-10-15 2003-10-30 Strickland Alan D. Dialysis solution including polyglycol osmotic agent
DE19955578C1 (de) * 1999-11-18 2001-09-06 Fresenius Medical Care De Gmbh Mehrkammerbehälter, mit Glucosekonzentratkompartiment und Salzsäurekonzentratkompartiment
US6582734B1 (en) * 2000-07-20 2003-06-24 Ecolab Inc. Antimicrobial composition useful for the treatment of bovine mastitis
WO2002049694A2 (en) * 2000-12-20 2002-06-27 Dialysis Solutions Inc. Sterile bicarbonate-free dialysis concentrate solutions
US6787039B2 (en) * 2001-01-26 2004-09-07 Degussa Ag Amino acid composition for hemodialysis
EP1377594A4 (en) * 2001-04-10 2004-06-30 Danisco Usa Inc POLYMERIZATION OF MONO AND DISACCHARIDES WITH MONOCARBOXYLIC ACIDS AND LACTONS
ITMI20020516A1 (it) * 2002-03-12 2003-09-12 Gambro Lundia Ab Liquidi per dialisi peritoneale emodialisi e reintegrazione
DE10217356B4 (de) * 2002-04-18 2012-03-29 Fresenius Medical Care Deutschland Gmbh Lösung für die Peritonealdialyse
US20040121982A1 (en) * 2002-12-20 2004-06-24 Leo Martis Biocompatible dialysis fluids containing icodextrins

Also Published As

Publication number Publication date
CN101843634B (zh) 2012-07-18
CA2510788A1 (en) 2004-07-15
AU2003299683A1 (en) 2004-07-22
TWI309569B (en) 2009-05-11
CN101843634A (zh) 2010-09-29
WO2004058277A1 (en) 2004-07-15
EP1585531B1 (en) 2019-09-11
JP4719470B2 (ja) 2011-07-06
US20040121982A1 (en) 2004-06-24
SG169228A1 (en) 2011-03-30
AR042795A1 (es) 2005-07-06
JP2014210780A (ja) 2014-11-13
JP2006513211A (ja) 2006-04-20
JP2013116352A (ja) 2013-06-13
EP1585531A1 (en) 2005-10-19
US20060128658A1 (en) 2006-06-15
TW200422045A (en) 2004-11-01
JP5947334B2 (ja) 2016-07-06
JP2010150281A (ja) 2010-07-08
JP5815581B2 (ja) 2015-11-17
JP2016166229A (ja) 2016-09-15
AU2003299683B2 (en) 2008-10-02
MXPA05006634A (es) 2005-09-30
CN1767838B (zh) 2010-05-26
ES2755946T3 (es) 2020-04-24
HK1088535A1 (en) 2006-11-10
KR101130017B1 (ko) 2012-04-20
CN1767838A (zh) 2006-05-03
KR20050089833A (ko) 2005-09-08

Similar Documents

Publication Publication Date Title
BR0317450A (pt) Fluidos de diálise biocompatìveis contendo icodextrinas
ATE496643T1 (de) Verwendung von antioxidantien zur verhinderung von oxidation und zur reduzierung von wirkstoffzersetzung in wirkstoffhaltigen medizinischen artikeln
ATE358505T1 (de) Beschichtete endovaskuläre vorrichtung
BR0208003A (pt) Soluções à base de bicarbonato para terapias com diálise
EP1196444B8 (en) Exendin-4 conjugates and their medical use
MX2010000809A (es) Inmovilizacion de colorantes y agentes antimicrobianos en un dispositivo medico.
EP1728076A4 (en) SYSTEM AND METHOD FOR PROVIDING OPTIMUM CONCENTRATIONS FOR MEDICAMENT INFUSIONS
WO2003079887A3 (en) Measuring blood flow rate or cardiac output
CA2403687A1 (en) Surgical articles
DE60311692D1 (de) Vaskulares Behandlungsgerät
NO996229D0 (no) Heparanase spesifikke molekylaere prober og deres anvendelse i forskning og medisin
PT99108A (pt) Processo de preparacao de uma composicao farmaceutica a base de portadores naoaquosos de perfluorocarbonetos ou silicone fluorado
HUP0102489A2 (hu) Biokémiai anyagok alkalmazása emberi test szerveiben található simaizomsejtek összehúzódása okozta egészségi állapotok megelőzésére és kezelésére alkalmas készítményekben
BR0110091A (pt) Composições e processos para terapia e diagnóstico de câncer de mama
ATE405277T1 (de) Substitutions-infusionflüssigkeit und zitratanticoagulation
ATE344049T1 (de) Medikament, enthaltend cyanidin-3-glykosid als wirkstoff gegen fettsucht und diabetes
CL2008003133A1 (es) Uso de albumina humana para la preparacion de un medicamento para el tratamiento de desordenes cognitivos en pacientes de alzheimer, donde el medicamento se encuentra en forma de solucion para recambio plasmatico y/o perfusion intravenosa.
BR0211400A (pt) Tratamento de distrofia muscular com células de sangue do cordão
Twardowski et al. Peritoneal dialysis access and exit site care
HUP0401188A2 (hu) Hiperelágazásos amilopektin sebészeti, gyógyító vagy diagnosztikai eljárásokban emlősöknél való alkalmazásra, különösen plazmatérfogat-növelőként
SE0301577D0 (sv) Low sodium solution
CN110585581A (zh) 螺旋式下肢皮肤消毒器
GB0606001D0 (en) Combination Of Cicletanine And An Oral Antidiabetic And/Or Blood Lipid-Lowering Agent For Treating Diabetes And Metabolic Syndrome
BRPI0411010A (pt) métodos para manter ou aumentar o número de glóbulos brancos do sangue em um paciente com cáncer submetido a tratamento quimioterapêutico para cáncer, para manter ou aumentar o número de plaquetas no sangue em um paciente com cáncer submetido a tratamento quimioterapêutico para cáncer e para reduzir a toxicidade gastrintestinal em um paciente com cáncer resultante de um agente quimioterapêutico anti-cáncer, composição farmacêutica, e, kit
BR0011714A (pt) Medicamento oftalmológico neuro-protetor e retino-protetor e utilização de um princìpio ativo de medicamento

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: PARA: INT. CL. A61K 31/718; A61M 1/28; A61P 13/00

Ipc: A61K 31/718 (2011.01), A61M 1/28 (2011.01), A61P 1

B25G Requested change of headquarter approved

Owner name: BAXTER INTERNATIONAL INC. (US) , BAXTER HEALTHCARE

Free format text: ENDERECO DO 2O DEPOSITANTE ALTERADO CONFORME SOLICITADO NA PETICAO NO 020110115944/RJ DE 11/11/2011.

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM OS ARTIGOS 8O COMBINADO COM ARTS. 11 E 13 E ARTS. 10 E 25 DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]