BR0215859A - Intermediários na produção de derivados de ácido fenoxiacético e métodos de uso do mesmo - Google Patents

Intermediários na produção de derivados de ácido fenoxiacético e métodos de uso do mesmo

Info

Publication number
BR0215859A
BR0215859A BR0215859-0A BR0215859A BR0215859A BR 0215859 A BR0215859 A BR 0215859A BR 0215859 A BR0215859 A BR 0215859A BR 0215859 A BR0215859 A BR 0215859A
Authority
BR
Brazil
Prior art keywords
production
intermediates
acid derivatives
methods
phenoxyacetic acid
Prior art date
Application number
BR0215859-0A
Other languages
English (en)
Inventor
Nobuyuki Tanaka
Tetsuro Tamai
Harunobu Mukaiyama
Takehiro Ishikawa
Junichi Kobayashi
Satoshi Akahane
Hiromu Harada
Original Assignee
Kissei Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kissei Pharmaceutical filed Critical Kissei Pharmaceutical
Publication of BR0215859A publication Critical patent/BR0215859A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734—Ethers
    • C07C69/736—Ethers the hydroxy group of the ester being etherified with a hydroxy compound having the hydroxy group bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/60—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/30—Compounds having groups
    • C07C43/315—Compounds having groups containing oxygen atoms singly bound to carbon atoms not being acetal carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/708—Ethers
    • C07C69/712—Ethers the hydroxy group of the ester being etherified with a hydroxy compound having the hydroxy group bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

"INTERMEDIáRIOS NA PRODUçãO DE DERIVADOS DE áCIDO FENOXIACéTICO E MéTODOS DE USO DO MESMO". Os intermediários representados pela seguinte fórmula geral (I) etc, que são úteis na produção de derivados de ácido fenoxiacéticos representados pela seguinte fórmula geral (X) ou sais farmaceuticamente aceitáveis deste tendo um efeito de estimulação do receptor de <225>3-adrenalina e sendo útil como preventivo ou remédio para obesidade, hiperglicemia, doenças causadas por distúrbios do movimento entérico, freq³ência urinária, incontinência urinária, depressão ou cálculos biliares; um processo para a produção desses intermediários; e um método de uso do mesmo: (I) (X) onde R^ 1^ e R^ 2^ independentemente representam cada alquila inferior.
BR0215859-0A 2002-09-05 2002-09-05 Intermediários na produção de derivados de ácido fenoxiacético e métodos de uso do mesmo BR0215859A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2002/009034 WO2004026807A1 (ja) 2002-09-05 2002-09-05 フェノキシ酢酸誘導体の製造中間体およびその使用方法

Publications (1)

Publication Number Publication Date
BR0215859A true BR0215859A (pt) 2005-07-05

Family

ID=32012201

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0215859-0A BR0215859A (pt) 2002-09-05 2002-09-05 Intermediários na produção de derivados de ácido fenoxiacético e métodos de uso do mesmo

Country Status (20)

Country Link
US (4) US7329771B2 (pt)
EP (1) EP1535897A4 (pt)
JP (1) JP4206071B2 (pt)
KR (1) KR100873941B1 (pt)
CN (1) CN1308283C (pt)
AU (1) AU2002328538B2 (pt)
BR (1) BR0215859A (pt)
CA (1) CA2494176C (pt)
EA (1) EA008002B1 (pt)
HK (1) HK1080453A1 (pt)
HR (1) HRP20050215A2 (pt)
HU (1) HUP0500596A2 (pt)
IL (1) IL167167A (pt)
MX (1) MXPA05002459A (pt)
NO (1) NO330806B1 (pt)
NZ (1) NZ538535A (pt)
RO (1) RO122357B1 (pt)
SI (1) SI21701A (pt)
UA (1) UA79498C2 (pt)
WO (1) WO2004026807A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2585037A1 (en) * 2004-10-26 2006-05-04 Kissei Pharmaceutical Co., Ltd. Synthesis of phenoxyacetic acid derivatives
EP1698648A1 (en) * 2005-03-01 2006-09-06 DSM IP Assets B.V. Hydroxy-aromatic compound, process for the preparation thereof, and use of the compound
WO2006059903A1 (en) * 2004-12-02 2006-06-08 Dsm Ip Assets B.V. Hydroxy-aromatic compound, process for the preparation thereof, and use of the compound
CA2605337A1 (en) * 2005-04-26 2006-11-23 Kissei Pharmaceutical Co., Ltd. Crystal polymorph of hydroxynorephedrin derivative hydrochloride
EP1878718A4 (en) * 2005-04-26 2010-07-28 Kissei Pharmaceutical CRYSTAL OF A HYDROXYNOREPHEDRINE DERIVATIVY HYDROCHLORIDE 1/4 HYDRATE
DE102007028924A1 (de) * 2007-06-22 2008-12-24 Saltigo Gmbh Verfahren zur Herstellung von 2-Hydroxyacetalen und den dazu korrespondierenden 2-Hydroxyalkanalen
US8603537B2 (en) 2012-04-02 2013-12-10 Egis Pharmaceuticals Plc Prasugrel containing quickly released stable oral pharmaceutical compositions
US9788029B2 (en) 2014-04-25 2017-10-10 Activevideo Networks, Inc. Intelligent multiplexing using class-based, multi-dimensioned decision logic for managed networks

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4338333A (en) * 1979-06-16 1982-07-06 Beecham Group Limited Ethanamine derivatives their preparation and use in pharmaceutical compositions
JPH06293664A (ja) * 1993-04-05 1994-10-21 Fujisawa Pharmaceut Co Ltd β３−アドレナリン作動薬の新規医薬用途
MY126489A (en) 1998-07-08 2006-10-31 Kissei Pharmaceutical Phenoxyacetic acid derivatives and medicinal compositions containing the same
FR2804679B1 (fr) * 2000-02-07 2002-04-26 Clariant France Sa Nouveaux composes phenoliques derives des dialcoxyethanals, leur procede de preparation et leur application

Also Published As

Publication number Publication date
US20080045740A1 (en) 2008-02-21
CN1308283C (zh) 2007-04-04
US7402692B2 (en) 2008-07-22
JP4206071B2 (ja) 2009-01-07
MXPA05002459A (es) 2005-06-03
CA2494176A1 (en) 2004-04-01
US7396954B2 (en) 2008-07-08
IL167167A (en) 2011-02-28
NZ538535A (en) 2006-08-31
NO20051683L (no) 2005-04-05
WO2004026807A1 (ja) 2004-04-01
EA200500447A1 (ru) 2005-08-25
NO330806B1 (no) 2011-07-18
EP1535897A4 (en) 2005-12-28
EP1535897A1 (en) 2005-06-01
HK1080453A1 (en) 2006-04-28
EA008002B1 (ru) 2007-02-27
US7393968B2 (en) 2008-07-01
CA2494176C (en) 2010-02-02
UA79498C2 (en) 2007-06-25
HUP0500596A2 (en) 2006-08-28
HRP20050215A2 (en) 2006-09-30
RO122357B1 (ro) 2009-04-30
SI21701A (en) 2005-08-31
US20060135605A1 (en) 2006-06-22
AU2002328538B2 (en) 2009-03-26
KR100873941B1 (ko) 2008-12-15
JPWO2004026807A1 (ja) 2006-01-12
CN1668572A (zh) 2005-09-14
US20080045739A1 (en) 2008-02-21
AU2002328538A1 (en) 2004-04-08
US7329771B2 (en) 2008-02-12
US20080045741A1 (en) 2008-02-21
KR20050095821A (ko) 2005-10-04

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 11A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2256 DE 01/04/2014.