BR0211025A - Um novo composto para o tratamento da impotência - Google Patents

Um novo composto para o tratamento da impotência

Info

Publication number
BR0211025A
BR0211025A BR0211025-3A BR0211025A BR0211025A BR 0211025 A BR0211025 A BR 0211025A BR 0211025 A BR0211025 A BR 0211025A BR 0211025 A BR0211025 A BR 0211025A
Authority
BR
Brazil
Prior art keywords
formula
impotence
compounds
treatment
present
Prior art date
Application number
BR0211025-3A
Other languages
English (en)
Other versions
BRPI0211025B1 (pt
BRPI0211025B8 (pt
Inventor
Baoshun Liu
Original Assignee
Baoshun Liu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25740515&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0211025(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Baoshun Liu filed Critical Baoshun Liu
Publication of BR0211025A publication Critical patent/BR0211025A/pt
Publication of BRPI0211025B1 publication Critical patent/BRPI0211025B1/pt
Publication of BRPI0211025B8 publication Critical patent/BRPI0211025B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"UM NOVO COMPOSTO PARA O TRATAMENTO DA IMPOTêNCIA". A presente invenção relaciona-se a novos compostos da fórmula (I) que são inibidores seletivos da fosfodiesterase, seus sais aceitáveis farmaceuticamente ou seus estereoisómeros. A presente invenção também fornece métodos para preparar os compostos da fórmula (I) e novos intermediários envolvidos na rota sintética dos compostos da fórmula (I). Os compostos da fórmula (I) da presente invenção não são somente efetivos para o tratamento de doenças de impotência, tais como disfunção erétil masculina, mas também possuem tais características como efetividade médica de longa duração e toxicidade mais baixa.
BRPI0211025A 2001-06-29 2002-06-21 um novo composto para o tratamento da impotência BRPI0211025B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN01129691 2001-06-29
CN02100198A CN1127506C (zh) 2001-06-29 2002-01-18 一种治疗阳痿的新化合物
PCT/CN2002/000433 WO2003016313A1 (fr) 2001-06-29 2002-06-21 Nouveaux composes de traitement de l'impuissance

Publications (3)

Publication Number Publication Date
BR0211025A true BR0211025A (pt) 2004-10-19
BRPI0211025B1 BRPI0211025B1 (pt) 2016-03-01
BRPI0211025B8 BRPI0211025B8 (pt) 2021-05-25

Family

ID=25740515

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0211025A BRPI0211025B8 (pt) 2001-06-29 2002-06-21 um novo composto para o tratamento da impotência

Country Status (18)

Country Link
US (1) US6960592B2 (pt)
EP (1) EP1400522B1 (pt)
JP (1) JP4469174B2 (pt)
KR (1) KR100878739B1 (pt)
CN (1) CN1127506C (pt)
AU (1) AU2002323774B2 (pt)
BR (1) BRPI0211025B8 (pt)
CA (1) CA2451990C (pt)
CY (1) CY1115687T1 (pt)
DK (1) DK1400522T3 (pt)
ES (1) ES2519441T3 (pt)
IL (1) IL159386A0 (pt)
MA (1) MA26117A1 (pt)
MX (1) MXPA03011929A (pt)
NZ (1) NZ530548A (pt)
PT (1) PT1400522E (pt)
RU (1) RU2279433C2 (pt)
WO (1) WO2003016313A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100360531C (zh) * 2003-12-18 2008-01-09 中国人民解放军军事医学科学院放射与辐射医学研究所 用于预防或治疗阳萎和性冷淡的新吡唑并嘧啶类化合物
EP2024369A4 (en) * 2006-06-05 2010-10-27 Matrix Lab Ltd NEW PROCESS FOR THE PREPARATION OF SILDENAFIL CITRATE
CN101914100B (zh) * 2010-04-13 2013-01-30 漆又毛 苯磺酰基二甲基哌嗪衍生物及制备方法
CN101891747B (zh) * 2010-07-02 2012-04-25 张南 抑制5型磷酸二酯酶的化合物及制备方法
CN109970744A (zh) * 2019-04-10 2019-07-05 重庆康刻尔制药有限公司 一种枸橼酸西地那非中间体的合成方法
CN112745323B (zh) * 2020-12-30 2021-10-29 北京悦康科创医药科技股份有限公司 枸橼酸爱地那非晶型h及其制备方法和用途
CN113350301B (zh) * 2021-06-03 2022-10-04 刘宝顺 一种治疗阳痿的新化合物中药蜜丸
WO2023109513A1 (zh) 2021-12-14 2023-06-22 真奥金银花药业有限公司 爱地那非或其盐在制备预防或治疗缺血性脑损伤的药物中的应用
KR102580664B1 (ko) 2023-01-25 2023-09-21 (주)나인팩토리커뮤니케이션 남성 성기에 부종감 및 온열감을 주고 혈행을 개선하는 피부 외용제 조성물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5250534A (en) * 1990-06-20 1993-10-05 Pfizer Inc. Pyrazolopyrimidinone antianginal agents
GB9013750D0 (en) * 1990-06-20 1990-08-08 Pfizer Ltd Therapeutic agents
GB9301192D0 (en) * 1993-06-09 1993-06-09 Trott Francis W Flower shaped mechanised table
US6200980B1 (en) * 1995-06-07 2001-03-13 Cell Pathways, Inc. Method of treating a patient having precancerous lesions with phenyl purinone derivatives
GB9612514D0 (en) * 1996-06-14 1996-08-14 Pfizer Ltd Novel process
AU4501199A (en) * 1998-06-03 1999-12-20 Almirall Prodesfarma S.A. 8-phenylxanthine derivatives and their use as phosphodiesterase inhibitors
ES2166270B1 (es) * 1999-07-27 2003-04-01 Almirall Prodesfarma Sa Derivados de 8-fenil-6,9-dihidro-(1,2,4,)triazolo(3,4-i)purin-5-ona.

Also Published As

Publication number Publication date
JP4469174B2 (ja) 2010-05-26
AU2002323774B2 (en) 2007-10-25
EP1400522A1 (en) 2004-03-24
CA2451990C (en) 2008-06-17
WO2003016313A1 (fr) 2003-02-27
MA26117A1 (fr) 2004-04-01
CN1393444A (zh) 2003-01-29
PT1400522E (pt) 2014-10-30
CY1115687T1 (el) 2017-01-25
US6960592B2 (en) 2005-11-01
BRPI0211025B1 (pt) 2016-03-01
IL159386A0 (en) 2004-06-01
MXPA03011929A (es) 2005-03-07
US20040152709A1 (en) 2004-08-05
EP1400522B1 (en) 2014-08-06
RU2279433C2 (ru) 2006-07-10
KR100878739B1 (ko) 2009-01-14
DK1400522T3 (da) 2014-11-10
CN1127506C (zh) 2003-11-12
KR20040010779A (ko) 2004-01-31
EP1400522A4 (en) 2006-04-05
JP2005500381A (ja) 2005-01-06
CA2451990A1 (en) 2003-02-27
ES2519441T3 (es) 2014-11-07
BRPI0211025B8 (pt) 2021-05-25
NZ530548A (en) 2005-04-29
RU2004102513A (ru) 2005-03-27

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: ALTERADA DA INT.CL: C07D 487/04, A61K 31/505

Ipc: C07D 487/04 (2011.01), A61K 31/505 (2011.01), A61P

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B25C Requirement related to requested transfer of rights

Owner name: BAOSHUN LIU (CN)

Free format text: A FIM DE ATENDER A TRANSFERENCIA, REQUERIDA ATRAVES DA PETICAO NO 15130000189/PR DE 25/01/2013, E NECESSARIO COMPLEMENTAR O VALOR DO SERVICO SOLICITADO, UMA VEZ QUE A EMPRESA CESSIONARIA NAO TEM DIREITO A TARIFA REDUZIDA, O DOCUMENTO DE CESSAO DEVE CONTER A LEGALIZACAO CONSULAR E DEVE SER APRESENTADA A GUIA DE CUMPRIMENTO DE EXIGENCIA.

B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements
B11N Dismissal: publication cancelled [chapter 11.14 patent gazette]
B25B Requested transfer of rights rejected

Owner name: BAOSHUN LIU (CN)

Free format text: INDEFERIDO(S) O(S) PEDIDO(S) DE TRANSFERENCIA(S) CONTIDO(S) NA PETICAO NO 15130000189, DE 25/01/2013, POR AUSENCIA DE CUMPRIMENTO DA EXIGENCIA PUBLICADA NA RPI NO 2222, DE 06/08/2013.

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B25B Requested transfer of rights rejected

Owner name: BAOSHUN LIU (CN)

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