BR0210839A - Sistema de recombinação, método para remover uma sequência de dna do dna cromossÈmico de uma célula ou organismo eucarióticos, organismo, cultura de célula, órgão, tecido, parte ou material de propagação transgênico, e, uso de um organismo ou de uma cultura de célula, órgão, tecido, parte ou material de propagação transgênico - Google Patents

Sistema de recombinação, método para remover uma sequência de dna do dna cromossÈmico de uma célula ou organismo eucarióticos, organismo, cultura de célula, órgão, tecido, parte ou material de propagação transgênico, e, uso de um organismo ou de uma cultura de célula, órgão, tecido, parte ou material de propagação transgênico

Info

Publication number
BR0210839A
BR0210839A BR0210839-9A BR0210839A BR0210839A BR 0210839 A BR0210839 A BR 0210839A BR 0210839 A BR0210839 A BR 0210839A BR 0210839 A BR0210839 A BR 0210839A
Authority
BR
Brazil
Prior art keywords
organism
tissue
organ
cell culture
transgenic
Prior art date
Application number
BR0210839-9A
Other languages
English (en)
Inventor
Holger Puchta
Christian Biesgen
Original Assignee
Sungene Gmbh & Co Kgaa
Inst F Pflanzengenetik U Kultu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sungene Gmbh & Co Kgaa, Inst F Pflanzengenetik U Kultu filed Critical Sungene Gmbh & Co Kgaa
Publication of BR0210839A publication Critical patent/BR0210839A/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8213—Targeted insertion of genes into the plant genome by homologous recombination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

"SISTEMA DE RECOMBINAçãO, MéTODO PARA REMOVER UMA SEQuêNCIA DE DNA DO DNA CROMOSSÈMICO DE UMA CéLULA OU ORGANISMO EUCARIóTICOS, ORGANISMO, CULTURA DE CéLULA, óRGãO, TECIDO, PARTE OU MATERIAL DE PROPAGAçãO TRANSGêNICO, E, USO DE UM ORGANISMO OU DE UMA CULTURA DE CéLULA, óRGãO, TECIDO, PARTE OU MATERIAL DE PROPAGAçãO TRANSGêNICO". A invenção diz respeito a sistemas de recombinação e a um método para remover seq³ências do DNA cromossómico de organismos eucarióticos. A invenção também diz respeito a organismos transgênicos (preferivelmente plantas), contendo os ditos sistemas ou produzido pelo dito método.
BR0210839-9A 2001-07-04 2002-07-02 Sistema de recombinação, método para remover uma sequência de dna do dna cromossÈmico de uma célula ou organismo eucarióticos, organismo, cultura de célula, órgão, tecido, parte ou material de propagação transgênico, e, uso de um organismo ou de uma cultura de célula, órgão, tecido, parte ou material de propagação transgênico BR0210839A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10131786A DE10131786A1 (de) 2001-07-04 2001-07-04 Rekombinationssysteme und Verfahren zum Entfernen von Nukleinsäuresequenzen aus dem Genom eukaryotischer Organismen
PCT/EP2002/007281 WO2003004659A2 (de) 2001-07-04 2002-07-02 Rekombinationssysteme und verfahren zum entfernen von nukleinsäuresequenzen aus dem genom eukaryotischer organismen

Publications (1)

Publication Number Publication Date
BR0210839A true BR0210839A (pt) 2004-07-13

Family

ID=7690173

Family Applications (2)

Application Number Title Priority Date Filing Date
BR0210839-9A BR0210839A (pt) 2001-07-04 2002-07-02 Sistema de recombinação, método para remover uma sequência de dna do dna cromossÈmico de uma célula ou organismo eucarióticos, organismo, cultura de célula, órgão, tecido, parte ou material de propagação transgênico, e, uso de um organismo ou de uma cultura de célula, órgão, tecido, parte ou material de propagação transgênico
BRPI0210839-9A BRPI0210839B1 (pt) 2001-07-04 2002-07-02 Sistema para recombinações múltiplas e sucessivas no mesmo organismo ou dna genômico, e, método para remover uma seqüência de dna do dna cromossômico de uma célula vegetal ou organismo vegetal

Family Applications After (1)

Application Number Title Priority Date Filing Date
BRPI0210839-9A BRPI0210839B1 (pt) 2001-07-04 2002-07-02 Sistema para recombinações múltiplas e sucessivas no mesmo organismo ou dna genômico, e, método para remover uma seqüência de dna do dna cromossômico de uma célula vegetal ou organismo vegetal

Country Status (12)

Country Link
US (1) US7736886B2 (pt)
EP (1) EP1407034B1 (pt)
JP (1) JP2004533267A (pt)
CN (1) CN100451123C (pt)
AR (2) AR034687A1 (pt)
AU (1) AU2002325859B2 (pt)
BR (2) BR0210839A (pt)
CA (1) CA2451492C (pt)
DE (1) DE10131786A1 (pt)
IL (1) IL159286A0 (pt)
MX (1) MXPA03011844A (pt)
WO (1) WO2003004659A2 (pt)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2306184C (en) * 1997-11-18 2007-05-15 Pioneer Hi-Bred International, Inc. Compositions and methods for genetic modification of plants
US7102055B1 (en) * 1997-11-18 2006-09-05 Pioneer Hi-Bred International, Inc. Compositions and methods for the targeted insertion of a nucleotide sequence of interest into the genome of a plant
US20100151556A1 (en) * 2002-03-15 2010-06-17 Cellectis Hybrid and single chain meganucleases and use thereof
US8206965B2 (en) * 2002-03-15 2012-06-26 Cellectis S.A. Hybrid and single chain meganucleases and use thereof
WO2009095742A1 (en) * 2008-01-31 2009-08-06 Cellectis New i-crei derived single-chain meganuclease and uses thereof
WO2004013333A2 (de) 2002-07-26 2004-02-12 Basf Plant Science Gmbh Revertierung der negativ-selektiven wirkung von negativen markerproteinen als selektionsverfahren
AU2004208030B2 (en) * 2003-01-28 2009-05-07 Cellectis Custom-made meganuclease and use thereof
US7476729B2 (en) * 2003-10-24 2009-01-13 Institut Curie Dbait and uses thereof
PT2025756E (pt) 2003-11-18 2011-09-28 Bayer Bioscience Nv Inserção direccionada de adn em plantas
WO2005090581A1 (en) * 2004-03-17 2005-09-29 Basf Plant Science Gmbh Improved constructs for marker excision based on dual-function selection marker
CN101218348B (zh) 2004-04-02 2014-07-30 帝斯曼知识产权资产管理有限公司 具有提高的同源重组效率的丝状真菌突变体
EP1794305A2 (en) * 2004-09-23 2007-06-13 BASF Plant Science GmbH Recombination cassettes and methods for sequence excision in plants
EP1669456A3 (en) 2004-12-11 2006-07-12 SunGene GmbH Expression cassettes for meristem-preferential expression in plants
WO2006074956A1 (en) * 2005-01-14 2006-07-20 Bayer Bioscience N.V. Improved plant transformation methods
AU2006232828B2 (en) * 2005-04-04 2011-01-27 Bayer Cropscience Nv. Methods and means for removal of a selected DNA sequence
AU2006257101B2 (en) 2005-04-19 2011-04-28 Basf Plant Science Gmbh Starchy-endosperm and/or germinating embryo-specific expression in mono-cotyledonous plants
BRPI0612862A2 (pt) 2005-07-18 2010-11-30 Pioneer Hi Bred Int polinucleotìdeo isolado, método para obtenção de uma célula transformada, método para obtenção de uma planta transformada, método de produção de recombinação de dna de sìtio especìfico, biblioteca isolada, método de geração de biblioteca de moléculas e método para selecionar sìtio de recombinação frt modificado
EP2341135A3 (en) 2005-10-18 2011-10-12 Precision Biosciences Rationally-designed meganucleases with altered sequence specificity and DNA-binding affinity
CA2638977A1 (en) 2006-03-17 2007-09-27 Basf Plant Science Gmbh D-amino acid selection for soybean
US20090124014A1 (en) * 2006-04-08 2009-05-14 Marco Alexander Van Den Berg Method for homologous recombination in fungal cells
EP2018434B1 (en) 2006-05-18 2011-03-02 Biogemma Method for performing homologous recombination in plants
WO2008037436A1 (en) 2006-09-28 2008-04-03 Bayer Bioscience N.V. Methods and means for removal of a selected dna sequence
WO2008099013A1 (en) 2007-02-16 2008-08-21 Basf Plant Science Gmbh Nucleic acid sequences for regulation of embryo-specific expression in monocotyledonous plants
AU2008257506B2 (en) * 2007-05-31 2013-09-05 Basf Plant Science Gmbh Method of excising a nucleic acid sequence from a plant genome
AU2008258782B2 (en) * 2007-06-05 2013-09-19 Bayer Cropscience Ag Methods and means for exact replacement of target DNA in eukaryotic organisms
EP2568048A1 (en) 2007-06-29 2013-03-13 Pioneer Hi-Bred International, Inc. Methods for altering the genome of a monocot plant cell
US9267132B2 (en) 2007-10-08 2016-02-23 Synthetic Genomics, Inc. Methods for cloning and manipulating genomes
US9273310B2 (en) * 2007-10-08 2016-03-01 Synthetic Genomics, Inc. Methods for cloning and manipulating genomes
AU2008335324A1 (en) * 2007-12-07 2009-06-18 Precision Biosciences, Inc. Rationally-designed meganucleases with recognition sequences found in DNase hypersensitive regions of the human genome
WO2009114321A2 (en) 2008-03-11 2009-09-17 Precision Biosciencs, Inc. Rationally-designed meganucleases for maize genome engineering
US20100071083A1 (en) * 2008-03-12 2010-03-18 Smith James J Temperature-dependent meganuclease activity
JP2011519558A (ja) * 2008-04-28 2011-07-14 プレシジョン バイオサイエンシズ，インク． 合理的に設計されたｄｎａ結合タンパク質とエフェクタードメインとの融合分子
ES2625941T3 (es) 2008-07-14 2017-07-21 Precision Biosciences, Inc. Secuencias de reconocimiento para meganucleasas derivadas de i-crei y sus usos
US20110269119A1 (en) 2009-10-30 2011-11-03 Synthetic Genomics, Inc. Encoding text into nucleic acid sequences
JP5902631B2 (ja) 2010-01-22 2016-04-13 ダウ アグロサイエンシィズ エルエルシー 標的化ゲノム変更
KR101137819B1 (ko) 2010-06-28 2012-06-27 대한민국 백합나무의 배발생조직 증식방법
WO2012017329A2 (en) * 2010-08-02 2012-02-09 Cellectis S.A. Method for targeted genomic events in algae
AU2011289283B2 (en) 2010-08-13 2015-04-30 Pioneer Hi-Bred International, Inc. Chimeric promoters and methods of use
US7919605B1 (en) 2010-08-30 2011-04-05 Amyris, Inc. Nucleic acids, compositions and methods for the excision of target nucleic acids
JP5740955B2 (ja) * 2010-12-10 2015-07-01 三菱レイヨン株式会社 ロドコッカス属細菌の形質転換のためのランダム遺伝子導入用ツール
CN102559704B (zh) * 2010-12-23 2014-08-27 中国科学院上海生命科学研究院 一种在丙酮丁醇梭菌中敲除基因的方法
EA201391373A1 (ru) 2011-03-23 2014-07-30 Пайонир Хай-Бред Интернэшнл, Инк. Способы получения сложного локуса трансгенных признаков
AU2012266597B2 (en) 2011-06-06 2016-09-22 Bayer Cropscience Nv Methods and means to modify a plant genome at a preselected site
US9290807B2 (en) * 2011-07-29 2016-03-22 Cambridge Epigenetix Limited Methods for detection of nucleotide modification
MX346439B (es) 2011-08-22 2017-03-17 Bayer Cropscience Nv Métodos y medios para modificar un genoma vegetal.
CN104039967A (zh) 2012-01-06 2014-09-10 先锋高级育种国际公司 筛选植物的在植物中诱导孤雌生殖的遗传元件的方法
US11518997B2 (en) 2012-04-23 2022-12-06 BASF Agricultural Solutions Seed US LLC Targeted genome engineering in plants
CN102703426A (zh) * 2012-05-21 2012-10-03 吴江汇杰生物科技有限公司 构建核酸库的方法、试剂及试剂盒
UA119135C2 (uk) 2012-09-07 2019-05-10 ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі Спосіб отримання трансгенної рослини
BR112015025006A2 (pt) 2013-04-02 2017-10-10 Bayer Cropscience Nv engenharia genômica alvejada em eucariontes
US20160201072A1 (en) 2013-08-22 2016-07-14 Pioneer Hi-Bred International, Inc. Genome modification using guide polynucleotide/cas endonuclease systems and methods of use
EP3362568A1 (en) 2015-10-16 2018-08-22 Pioneer Hi-Bred International, Inc. Methods and compositions for transformation comprising negative selection markers
US11021713B2 (en) 2016-05-25 2021-06-01 Cargill, Incorporated Engineered nucleases to generate deletion mutants in plants
IL262975B2 (en) 2016-05-26 2023-03-01 Nunhems Bv Plants that produce fruit without pits
US11359234B2 (en) 2016-07-01 2022-06-14 Microsoft Technology Licensing, Llc Barcoding sequences for identification of gene expression
US20180004537A1 (en) 2016-07-01 2018-01-04 Microsoft Technology Licensing, Llc Molecular State Machines
WO2018111640A1 (en) 2016-12-14 2018-06-21 Dow Agrosciences Llc Reconstruction of site specific nuclease binding sites
DK3501268T3 (da) 2017-12-22 2021-11-08 Kws Saat Se & Co Kgaa Regenerering af planter i tilstedeværelse af histondeacetylase hæmmere
EP3508581A1 (en) 2018-01-03 2019-07-10 Kws Saat Se Regeneration of genetically modified plants
US20200362366A1 (en) 2018-01-12 2020-11-19 Basf Se Gene underlying the number of spikelets per spike qtl in wheat on chromosome 7a
EP3545756A1 (en) 2018-03-28 2019-10-02 KWS SAAT SE & Co. KGaA Regeneration of plants in the presence of inhibitors of the histone methyltransferase ezh2
EP3567111A1 (en) 2018-05-09 2019-11-13 KWS SAAT SE & Co. KGaA Gene for resistance to a pathogen of the genus heterodera
WO2019238908A1 (en) 2018-06-15 2019-12-19 KWS SAAT SE & Co. KGaA Methods for enhancing genome engineering efficiency
US11291176B2 (en) 2018-06-15 2022-04-05 Nunhems B.V. Seedless watermelon plants comprising modifications in an ABC transporter gene
BR112020025311A2 (pt) 2018-06-15 2021-03-09 KWS SAAT SE & Co. KGaA Métodos para melhorar a engenharia e regeneração do genoma em planta ii
WO2019238909A1 (en) 2018-06-15 2019-12-19 KWS SAAT SE & Co. KGaA Methods for improving genome engineering and regeneration in plant
EP3623379A1 (en) 2018-09-11 2020-03-18 KWS SAAT SE & Co. KGaA Beet necrotic yellow vein virus (bnyvv)-resistance modifying gene
CN113166776A (zh) 2019-01-04 2021-07-23 嘉吉公司 用于在植物中产生突变的工程化核酸酶
CN113490747A (zh) 2019-01-29 2021-10-08 华威大学 用于提高基因组工程化效率的方法
EP3708651A1 (en) 2019-03-12 2020-09-16 KWS SAAT SE & Co. KGaA Improving plant regeneration
EP3757219A1 (en) 2019-06-28 2020-12-30 KWS SAAT SE & Co. KGaA Enhanced plant regeneration and transformation by using grf1 booster gene
CA3157872A1 (en) 2019-11-12 2021-05-20 Otto Torjek Gene for resistance to a pathogen of the genus heterodera
CN111534538B (zh) * 2020-05-11 2022-02-01 山西大学 一种快速筛选非转基因定点突变植物的方法
EP4019639A1 (en) 2020-12-22 2022-06-29 KWS SAAT SE & Co. KGaA Promoting regeneration and transformation in beta vulgaris
EP4019638A1 (en) 2020-12-22 2022-06-29 KWS SAAT SE & Co. KGaA Promoting regeneration and transformation in beta vulgaris

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6395959B1 (en) * 1992-05-05 2002-05-28 Institut Pasteur Nucleotide sequence encoding the enzyme I SceI and the use thereof
US5792632A (en) 1992-05-05 1998-08-11 Institut Pasteur Nucleotide sequence encoding the enzyme I-SceI and the uses thereof
US5527695A (en) * 1993-01-29 1996-06-18 Purdue Research Foundation Controlled modification of eukaryotic genomes

Also Published As

Publication number Publication date
US7736886B2 (en) 2010-06-15
US20050172365A1 (en) 2005-08-04
MXPA03011844A (es) 2005-03-07
JP2004533267A (ja) 2004-11-04
CA2451492C (en) 2014-12-16
WO2003004659A2 (de) 2003-01-16
IL159286A0 (en) 2004-06-01
DE10131786A1 (de) 2003-01-16
EP1407034A2 (de) 2004-04-14
WO2003004659A8 (de) 2004-04-22
CA2451492A1 (en) 2003-01-16
CN1628174A (zh) 2005-06-15
EP1407034B1 (de) 2016-09-07
AU2002325859B2 (en) 2008-05-29
BRPI0210839B1 (pt) 2019-02-26
CN100451123C (zh) 2009-01-14
AR034687A1 (es) 2004-03-03
AR086031A2 (es) 2013-11-13
WO2003004659A3 (de) 2003-09-25

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