ES2187648T3 - Metodo para la administracion de farmacos para terapia genica. - Google Patents

Metodo para la administracion de farmacos para terapia genica.

Info

Publication number
ES2187648T3
ES2187648T3 ES96913661T ES96913661T ES2187648T3 ES 2187648 T3 ES2187648 T3 ES 2187648T3 ES 96913661 T ES96913661 T ES 96913661T ES 96913661 T ES96913661 T ES 96913661T ES 2187648 T3 ES2187648 T3 ES 2187648T3
Authority
ES
Spain
Prior art keywords
administration
pharmacos
gene therapy
pharmaceuticals
organs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96913661T
Other languages
English (en)
Inventor
Karl Tryggvason
Olavi Lukkarinen
Pirkko Heikkila
Teija Parpala
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2187648T3 publication Critical patent/ES2187648T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

SE DESCRIBE UN METODO PARA LA ADMINISTRACION EFICAZ DE COMPUESTOS FARMACEUTICOS DE TERAPIA GENICA CON VECTOR VIRAL EN UNA SOLUCION PERFUNDIDA OXIGENADA RECIRCULANTE, A UN TEJIDO DIANA QUE COMPRENDE PONER EN CONTACTO EL TEJIDO DIANA CON UN COMPUESTO FARMACEUTICO DE TERAPIA GENICA CON VECTOR VIRAL EN UNA SOLUCION DE PERFUSION OXIGENADA RECIRCULANTE, EN EL QUE DICHA SOLUCION SE MANTIENE A APROXIMADAMENTE 37 UNA ADMINISTRACION EFICAZ DEL COMPUESTO FARMACEUTICO DE TERAPIA GENICA CON VECTOR VIRAL.
ES96913661T 1995-05-16 1996-05-16 Metodo para la administracion de farmacos para terapia genica. Expired - Lifetime ES2187648T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US44218995A 1995-05-16 1995-05-16

Publications (1)

Publication Number Publication Date
ES2187648T3 true ES2187648T3 (es) 2003-06-16

Family

ID=23755860

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96913661T Expired - Lifetime ES2187648T3 (es) 1995-05-16 1996-05-16 Metodo para la administracion de farmacos para terapia genica.

Country Status (7)

Country Link
US (2) US5871464A (es)
EP (1) EP0831919B1 (es)
AT (1) ATE226094T1 (es)
AU (1) AU5658196A (es)
DE (1) DE69624355T2 (es)
ES (1) ES2187648T3 (es)
WO (1) WO1996036363A1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6342214B1 (en) * 1995-05-16 2002-01-29 Karl Tryggvason Method for viral vector delivery
US6638264B1 (en) * 1995-05-16 2003-10-28 Biostratum Incorporation Perfusion apparatus and methods for pharmaceutical delivery
KR19980086811A (ko) * 1997-05-08 1998-12-05 니시무로 타이조 부가정보 매입과 재생을 위한 장치와 방법 및 그 기록 매체
CN1347450A (zh) * 1999-04-09 2002-05-01 阿文蒂斯药物股份有限公司 用于保存感染性重组腺病毒的组合物
US20070166292A1 (en) * 1999-04-14 2007-07-19 Breonics, Inc. System for exsanguinous metabolic support of an organ or tissue
US6455257B1 (en) * 2001-02-16 2002-09-24 Richard D. Fuerle Designer diseases
US20040170950A1 (en) * 2002-09-12 2004-09-02 Prien Samuel D. Organ preservation apparatus and methods
US20050153271A1 (en) * 2004-01-13 2005-07-14 Wenrich Marshall S. Organ preservation apparatus and methods
US7722596B2 (en) * 2004-02-26 2010-05-25 Osprey Medical, Inc. Regional cardiac tissue treatment
US20060182724A1 (en) * 2005-02-15 2006-08-17 Riordan Neil H Method for expansion of stem cells
US8152786B2 (en) * 2006-11-07 2012-04-10 Osprey Medical, Inc. Collection catheter and kit
US20080145919A1 (en) * 2006-12-18 2008-06-19 Franklin Thomas D Portable organ and tissue preservation apparatus, kit and methods
US9050400B2 (en) * 2008-08-12 2015-06-09 Osprey Medical, Inc. Remote sensing catheter system and methods
US20100041984A1 (en) * 2008-08-12 2010-02-18 James Edward Shapland Impedance sensing device and catheter system
US9320269B2 (en) 2009-09-25 2016-04-26 John Brassil Organ preservation system
US9295816B2 (en) * 2009-12-09 2016-03-29 Osprey Medical, Inc. Catheter with distal and proximal ports
US9211372B2 (en) 2011-08-11 2015-12-15 Osprey Medical, Inc. Systems and methods for limb treatment

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5328470A (en) * 1989-03-31 1994-07-12 The Regents Of The University Of Michigan Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor
US5521291A (en) * 1991-09-30 1996-05-28 Boehringer Ingelheim International, Gmbh Conjugates for introducing nucleic acid into higher eucaryotic cells
US5252479A (en) * 1991-11-08 1993-10-12 Research Corporation Technologies, Inc. Safe vector for gene therapy
US5338662A (en) * 1992-09-21 1994-08-16 Bio-Preserve Medical Corporation Organ perfusion device
US5336178A (en) * 1992-11-02 1994-08-09 Localmed, Inc. Intravascular catheter with infusion array
US5382229A (en) * 1993-09-21 1995-01-17 Abbott Laboratories Irrigation solution re-circulating system

Also Published As

Publication number Publication date
DE69624355T2 (de) 2003-06-12
US6689090B1 (en) 2004-02-10
DE69624355D1 (de) 2002-11-21
WO1996036363A1 (en) 1996-11-21
US5871464A (en) 1999-02-16
AU5658196A (en) 1996-11-29
EP0831919B1 (en) 2002-10-16
EP0831919A1 (en) 1998-04-01
ATE226094T1 (de) 2002-11-15

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