|
PE20040167A1
(es)
*
|
2002-03-28 |
2004-05-26 |
Novartis Ag |
Amidas del acido sulfamico
|
|
CA2485167A1
(en)
*
|
2002-05-07 |
2003-11-20 |
The Government Of The United States Of America |
Polydiazeniumdiolated cyclic polyamines with polyphasic nitric oxide release and related compounds, compositions comprising same and methods of using same
|
|
KR20080058509A
(ko)
*
|
2002-06-11 |
2008-06-25 |
일라이 릴리 앤드 캄파니 |
흥분성 아미노산의 전구약물
|
|
EP1535616B1
(en)
|
2002-08-22 |
2009-05-13 |
Dainippon Sumitomo Pharma Co., Ltd. |
Remedy for integration dysfunction syndrome
|
|
DE10238724A1
(de)
*
|
2002-08-23 |
2004-03-04 |
Bayer Ag |
Alkyl-substituierte Pyrazolpyrimidine
|
|
DE10238722A1
(de)
|
2002-08-23 |
2004-03-11 |
Bayer Ag |
Selektive Phosphodiesterase 9A-Inhibitoren als Arzneimittel zur Verbesserung kognitiver Prozesse
|
|
DE10238723A1
(de)
*
|
2002-08-23 |
2004-03-11 |
Bayer Ag |
Phenyl-substituierte Pyrazolyprimidine
|
|
WO2004062625A2
(en)
|
2003-01-07 |
2004-07-29 |
Merck & Co., Inc. |
Macrocyclic beta-secretase inhibitors for treatment of alzheimer's disease
|
|
US7521481B2
(en)
|
2003-02-27 |
2009-04-21 |
Mclaurin Joanne |
Methods of preventing, treating and diagnosing disorders of protein aggregation
|
|
DE10315569A1
(de)
*
|
2003-04-05 |
2004-10-14 |
Merck Patent Gmbh |
Substituierte Pyrazolverbindungen
|
|
DE10315573A1
(de)
|
2003-04-05 |
2004-10-14 |
Merck Patent Gmbh |
Substituierte Pyrazole
|
|
DE10315572A1
(de)
*
|
2003-04-05 |
2004-10-14 |
Merck Patent Gmbh |
Substituierte Pyrazole
|
|
DE10315571A1
(de)
*
|
2003-04-05 |
2004-10-14 |
Merck Patent Gmbh |
Pyrazolverbindungen
|
|
SE0301009D0
(sv)
*
|
2003-04-07 |
2003-04-07 |
Astrazeneca Ab |
Novel compounds
|
|
SE0301010D0
(sv)
*
|
2003-04-07 |
2003-04-07 |
Astrazeneca Ab |
Novel compounds
|
|
US7732162B2
(en)
*
|
2003-05-05 |
2010-06-08 |
Probiodrug Ag |
Inhibitors of glutaminyl cyclase for treating neurodegenerative diseases
|
|
DE10320785A1
(de)
*
|
2003-05-09 |
2004-11-25 |
Bayer Healthcare Ag |
6-Arylmethyl-substituierte Pyrazolopyrimidine
|
|
US8044060B2
(en)
*
|
2003-05-09 |
2011-10-25 |
Boehringer Ingelheim International Gmbh |
6-cyclylmethyl- and 6-alkylmethyl pyrazolo[3,4-D]pyrimidines, methods for their preparation and methods for their use to treat impairments of perception, concentration learning and/or memory
|
|
DE10326940A1
(de)
*
|
2003-06-16 |
2005-01-05 |
Merck Patent Gmbh |
Indol-Derivate
|
|
DK1633774T3
(da)
|
2003-06-18 |
2010-05-25 |
Tranzyme Pharma Inc |
Makrocykliske motilinreceptorantagonister
|
|
KR101113630B1
(ko)
*
|
2003-06-23 |
2012-02-13 |
다이닛본 스미토모 세이야꾸 가부시끼가이샤 |
노인성 치매 치료제
|
|
AU2004257025B9
(en)
*
|
2003-06-27 |
2010-05-27 |
Msd K.K. |
Heteroaryloxy nitrogenous saturated heterocyclic derivative
|
|
SA04250253B1
(ar)
|
2003-08-21 |
2009-11-10 |
استرازينيكا ايه بي |
احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن
|
|
GB0325830D0
(en)
*
|
2003-11-05 |
2003-12-10 |
Novartis Ag |
Organic compounds
|
|
MXPA06007017A
(es)
|
2003-12-18 |
2006-08-31 |
Janssen Pharmaceutica Nv |
Derivados de pirido y pirimidopirimidina como agentes antiproliferativos.
|
|
DE102004001873A1
(de)
*
|
2004-01-14 |
2005-09-29 |
Bayer Healthcare Ag |
Cyanopyrimidinone
|
|
HRP20040104A2
(en)
*
|
2004-01-30 |
2005-10-31 |
Pliva-Istra�iva�ki institut d.o.o. |
Use of benzonaphthoazulenes for the manufacture of pharmaceutical formulations for the treatment and prevention of central nervous system diseases and disorders
|
|
CA2554050A1
(en)
*
|
2004-02-04 |
2005-08-18 |
Neurosearch A/S |
Diazabicyclic aryl derivatives as cholinergic receptor modulators
|
|
DE602005015682D1
(de)
*
|
2004-02-04 |
2009-09-10 |
Neurosearch As |
Dimere azacyclische verbindungen und deren verwendung
|
|
US20070160537A1
(en)
*
|
2004-02-20 |
2007-07-12 |
Takeo Ishiyama |
In vivo screening method of therapeutic agent for memory/learning dysfunctions by schizophrenia
|
|
JP2007528400A
(ja)
|
2004-03-09 |
2007-10-11 |
エラン ファーマシューティカルズ,インコーポレイテッド |
置換ヒドロキシエチルアミン系のアスパラギン酸プロテアーゼ阻害薬
|
|
ATE490959T1
(de)
*
|
2004-03-31 |
2010-12-15 |
Janssen Pharmaceutica Nv |
Heterocyclische nichtimidazolverbindungen als modulatoren des histamin-h3-rezeptors
|
|
US7423147B2
(en)
*
|
2004-03-31 |
2008-09-09 |
Janssen Pharmaceutical, N.V. |
Pyridine compounds as histamine H3 modulators
|
|
GB0415320D0
(en)
*
|
2004-07-08 |
2004-08-11 |
Astrazeneca Ab |
Novel compounds
|
|
WO2006010095A2
(en)
|
2004-07-09 |
2006-01-26 |
Elan Pharmaceuticals Inc. |
Oxime derivative substituted hydroxyethylamine aspartyl protease inhibitors
|
|
WO2006006740A1
(ja)
*
|
2004-07-14 |
2006-01-19 |
Japan Tobacco Inc. |
3−アミノベンズアミド化合物及びバニロイド受容体1型(vr1)活性阻害剤
|
|
MX2007000480A
(es)
*
|
2004-07-15 |
2007-03-29 |
Japan Tobacco Inc |
Compuesto de benzamida fusionado e inhibidor de actividad de receptor de vainilloide 1.
|
|
US7494986B2
(en)
*
|
2004-07-20 |
2009-02-24 |
Bristol-Myers Squibb Company |
Cycloalkylamine derivatives as NK-1/SSRI antagonists
|
|
CA2575340A1
(en)
*
|
2004-07-28 |
2006-02-09 |
Schering Corporation |
Macrocyclic beta-secretase inhibitors
|
|
US8426429B2
(en)
|
2004-08-06 |
2013-04-23 |
Jansssen Pharmaceutica N.V. |
2-amino-quinazoline derivatives useful as inhibitors of β-secretase (BACE)
|
|
US8436006B2
(en)
|
2004-08-06 |
2013-05-07 |
Jansssen Pharmaceutica N.V. |
2-amino-quinazoline derivatives useful as inhibitors of β-secretase (BACE)
|
|
US8383637B2
(en)
|
2004-08-06 |
2013-02-26 |
Jansssen Pharmaceutica N.V. |
2-amino-quinazoline derivatives useful as inhibitors of β-secretase (BACE)
|
|
GB0418830D0
(en)
|
2004-08-24 |
2004-09-22 |
Astrazeneca Ab |
Novel compounds
|
|
JP2008511643A
(ja)
*
|
2004-08-27 |
2008-04-17 |
エラン ファーマシューティカルズ,インコーポレイテッド |
置換エタノール環式アミンアスパラギン酸プロテアーゼ阻害剤を用いて、アミロイドーシスを治療する方法
|
|
GB0422057D0
(en)
*
|
2004-10-05 |
2004-11-03 |
Astrazeneca Ab |
Novel compounds
|
|
TW200630337A
(en)
*
|
2004-10-14 |
2006-09-01 |
Euro Celtique Sa |
Piperidinyl compounds and the use thereof
|
|
WO2006047415A2
(en)
*
|
2004-10-26 |
2006-05-04 |
Janssen Pharmaceutica, N.V. |
Factor xa compounds
|
|
US7678783B2
(en)
*
|
2004-11-17 |
2010-03-16 |
Merck Sharp & Dohme Corp. |
Macrocyclic tertiary amine beta-secretase inhibitors for the treatment of alzheimer's disease
|
|
UY29223A1
(es)
*
|
2004-11-23 |
2006-06-30 |
Astrazeneca Ab |
Ácidos fenoxiacéticos sustituidos, composiciones farmacéuticas que los contienen y procesos para su preparación
|
|
US7951949B2
(en)
|
2004-11-23 |
2011-05-31 |
Merck, Sharp & Dohme, Corp. |
Macrocyclic aminopyridyl beta-secretase inhibitors for the treatment of Alzheimer's disease
|
|
NI200700147A
(es)
|
2004-12-08 |
2019-05-10 |
Janssen Pharmaceutica Nv |
Derivados de quinazolina inhibidores de cinasas dirigidos a multip
|
|
JO3088B1
(ar)
*
|
2004-12-08 |
2017-03-15 |
Janssen Pharmaceutica Nv |
مشتقات كوينازولين كبيرة الحلقات و استعمالها بصفتها موانع كينيز متعددة الاهداف
|
|
NZ590148A
(en)
*
|
2004-12-30 |
2012-04-27 |
Janssen Pharmaceutica Nv |
Piperazinyl and piperidinyl ureas as modulators of fatty acid amide hydrolase
|
|
GB0500683D0
(en)
*
|
2005-01-13 |
2005-02-23 |
Novartis Ag |
Organic compounds
|
|
KR20070102514A
(ko)
*
|
2005-01-13 |
2007-10-18 |
노파르티스 아게 |
Bace 억제제로서 유용한 마크로시클릭 화합물
|
|
GB0504960D0
(en)
*
|
2005-03-10 |
2005-04-20 |
Arakis Ltd |
Benzoxazocines
|
|
NZ562314A
(en)
|
2005-04-08 |
2010-02-26 |
Comentis Inc |
Compounds which inhibit beta-secretase activity and methods of use thereof
|
|
US8778919B2
(en)
*
|
2005-06-30 |
2014-07-15 |
Janssen Pharmaceutica Nv |
Cyclic anilino—pyridinotriazines
|
|
US7851474B2
(en)
*
|
2005-08-02 |
2010-12-14 |
Neurogen Corporation |
Dipiperazinyl ketones and related analogues
|
|
EP1937632A1
(en)
|
2005-10-06 |
2008-07-02 |
Astra Zeneca AB |
Novel compounds
|
|
TW200745003A
(en)
|
2005-10-06 |
2007-12-16 |
Astrazeneca Ab |
Novel compounds
|
|
WO2007047305A1
(en)
|
2005-10-12 |
2007-04-26 |
Elan Pharmaceuticals, Inc. |
Methods of treating amyloidosis using cyclopropyl derivative aspartyl protease inhibitors
|
|
EP1966198B1
(en)
|
2005-10-25 |
2011-03-16 |
Janssen Pharmaceutica NV |
2-amino-3,4-dihydro-pyrido[3,4-d]pyrimidine derivatives useful as inhibitors of beta-secretase (bace)
|
|
EP1948630A2
(en)
*
|
2005-11-05 |
2008-07-30 |
AstraZeneca AB |
Novel compounds
|
|
TW200732296A
(en)
*
|
2005-12-15 |
2007-09-01 |
Astrazeneca Ab |
Novel compounds
|
|
DE102005062986A1
(de)
*
|
2005-12-28 |
2007-07-05 |
Grünenthal GmbH |
Substituierte Propiolsäureamide und ihre Verwendung zur Herstellung von Arzneimitteln
|
|
US7906508B2
(en)
*
|
2005-12-28 |
2011-03-15 |
Japan Tobacco Inc. |
3,4-dihydrobenzoxazine compounds and inhibitors of vanilloid receptor subtype 1 (VRI) activity
|
|
GB0526614D0
(en)
|
2005-12-30 |
2006-02-08 |
Novartis Ag |
Organic compounds
|
|
US7868022B2
(en)
|
2006-02-06 |
2011-01-11 |
Janssen Pharmaceutica Nv |
2-amino-quinoline derivatives useful as inhibitors of β-secretase (BACE)
|
|
US7932261B2
(en)
|
2006-02-06 |
2011-04-26 |
Janssen Pharmaceutica Nv |
Macrocycle derivatives useful as inhibitors of β-secretase (BACE)
|
|
US7776882B2
(en)
|
2006-02-06 |
2010-08-17 |
Baxter Ellen W |
2-amino-3,4-dihydro-quinoline derivatives useful as inhibitors of β-secretase (BACE)
|
|
AU2007216531A1
(en)
*
|
2006-02-14 |
2007-08-23 |
Neurosearch A/S |
Novel diazabicycloalkane derivatives and their medical use
|
|
AU2007225273A1
(en)
*
|
2006-03-10 |
2007-09-20 |
Neurogen Corporation |
Piperazinyl oxoalkyl tetrahydroisoquinolines and related analogues
|
|
CA2645289A1
(en)
*
|
2006-03-10 |
2007-09-20 |
Janssen Pharmaceutica, N.V. |
Pyridine-containing macroheterocylic compounds as kinase inhibitors
|
|
WO2007110363A1
(en)
*
|
2006-03-24 |
2007-10-04 |
Neurosearch A/S |
Novel guanidine derivatives and their medical use
|
|
WO2007110449A1
(en)
*
|
2006-03-29 |
2007-10-04 |
Euro-Celtique S.A. |
Benzenesulfonamide compounds and their use
|
|
US8791264B2
(en)
*
|
2006-04-13 |
2014-07-29 |
Purdue Pharma L.P. |
Benzenesulfonamide compounds and their use as blockers of calcium channels
|
|
WO2007118854A1
(en)
*
|
2006-04-13 |
2007-10-25 |
Euro-Celtique S.A. |
Benzenesulfonamide compounds and the use thereof
|
|
US20090118265A1
(en)
*
|
2006-05-23 |
2009-05-07 |
Dan Peters |
Novel 1,4-diaza-bicyclo[3.2.2]nonane derivatives and their medical use
|
|
AU2007267177A1
(en)
*
|
2006-05-30 |
2007-12-06 |
Neurosearch A/S |
Novel 1,4-diaza-bicyclo[3.2.2]nonyl pyrimidinyl derivative and its medical use
|
|
UA100669C2
(ru)
*
|
2006-06-01 |
2013-01-25 |
Санофі-Авентіс |
Спироциклические нитрилы как ингибиторы протеазы, способ их получения (варианты) и лекарственное средство на их основе
|
|
JP2009542778A
(ja)
*
|
2006-07-13 |
2009-12-03 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ |
Mtkiキナゾリン誘導体
|
|
BRPI0715437A2
(pt)
*
|
2006-07-20 |
2013-04-16 |
Novartis Ag |
lactamas macrocÍclicas
|
|
JP2009544599A
(ja)
*
|
2006-07-20 |
2009-12-17 |
ノバルティス アクチエンゲゼルシャフト |
Bace阻害剤として有用な大環状化合物
|
|
CA2679735A1
(en)
*
|
2007-03-01 |
2008-09-12 |
Janssen Pharmaceutica N.V. |
Tetrahydroisoquinoline compounds as modulators of the histamine h3 receptor
|
|
WO2008116302A1
(en)
*
|
2007-03-26 |
2008-10-02 |
Merck Frosst Canada Ltd. |
Cathepsin cysteine protease inhibitors
|
|
WO2008124118A1
(en)
*
|
2007-04-09 |
2008-10-16 |
Purdue Pharma L.P. |
Benzenesulfonyl compounds and the use therof
|
|
UA100983C2
(ru)
*
|
2007-07-05 |
2013-02-25 |
Астразенека Аб |
Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты
|
|
AU2008281849B2
(en)
|
2007-07-27 |
2013-11-28 |
Janssen Pharmaceutica Nv |
Pyrrolopyrimidines
|
|
JP2010536725A
(ja)
*
|
2007-08-17 |
2010-12-02 |
ノイロサーチ アクティーゼルスカブ |
ニコチン性アセチルコリン受容体リガンドとして有用な新規1,4−ジアザ−ビシクロ〔3.2.2〕ノニルオキサジアゾリル誘導体
|
|
US7935695B2
(en)
*
|
2007-08-17 |
2011-05-03 |
Neurosearch A/S |
1,4-diaza-bicyclo[3.2.2]nonyl heteroaryl derivatives useful as nicotinic acetylcholine receptor ligands
|
|
WO2009040659A2
(en)
*
|
2007-09-28 |
2009-04-02 |
Purdue Pharma L.P. |
Benzenesulfonamide compounds and the use thereof
|
|
CN101868454A
(zh)
*
|
2007-11-20 |
2010-10-20 |
詹森药业有限公司 |
作为组胺h3受体调节剂的环烷基氧基吡啶化合物和杂环烷基氧基吡啶化合物
|
|
JP5498392B2
(ja)
*
|
2007-11-30 |
2014-05-21 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
1,5−ジヒドロ−ピラゾロ[3,4−d]ピリミジン−4−オン誘導体及びcns障害の治療のためのpde9aモジュレーターとしてのそれらの使用
|
|
WO2009097278A1
(en)
|
2008-01-28 |
2009-08-06 |
Janssen Pharmaceutica N.V. |
6-SUBSTITUTED-THIO-2-AMINO-QUINOLINE DERIVATIVES USEFUL AS INHIBITORS OF β-SECRETASE (BACE)
|
|
EP2240472B1
(en)
|
2008-01-29 |
2012-11-21 |
Janssen Pharmaceutica NV |
2-amino-quinoline derivatives useful as inhibitors of beta-secretase (bace)
|
|
UA105362C2
(en)
|
2008-04-02 |
2014-05-12 |
Бьорингер Ингельхайм Интернациональ Гмбх |
1-heterocyclyl-1, 5-dihydro-pyrazolo [3, 4-d] pyrimidin-4-one derivatives and their use as pde9a modulators
|
|
US8236792B2
(en)
*
|
2008-05-23 |
2012-08-07 |
Janssen Pharmaceutica Nv |
Substituted pyrrolidine amides as modulators of the histamine H3 receptor
|
|
KR20110063447A
(ko)
|
2008-09-08 |
2011-06-10 |
베링거 인겔하임 인터내셔날 게엠베하 |
피라졸로피리미딘 및 cns 장애의 치료를 위한 이들의 용도
|
|
PT2414363E
(pt)
|
2009-03-31 |
2014-02-26 |
Boehringer Ingelheim Int |
Derivados de 1-heterociclil-1,5-di-hidro-pirazolo[3,4- d]pirimidin-4-ona e sua utilização como moduladores de pde9a
|
|
EP2427451B1
(en)
*
|
2009-05-07 |
2019-03-20 |
PRISM BioLab Co., Ltd. |
Alpha helix mimetics and methods relating thereto
|
|
BRPI1011683B8
(pt)
*
|
2009-06-19 |
2021-05-25 |
D Western Therapeutics Inst Inc |
derivados de isoquinolina substituída, suas composições farmacêuticas e seus usos
|
|
AU2010262643B2
(en)
*
|
2009-06-19 |
2015-02-19 |
Abbvie Inc. |
Diazahomoadamantane derivatives and methods of use thereof
|
|
TW201118099A
(en)
*
|
2009-08-12 |
2011-06-01 |
Boehringer Ingelheim Int |
New compounds for the treatment of CNS disorders
|
|
EP2603511B1
(en)
|
2010-08-12 |
2017-03-15 |
Boehringer Ingelheim International GmbH |
6-cycloalkyl-1, 5-dihydro-pyrazolo [3, 4-d] pyrimidin-4-one derivatives and their use as pde9a inhibitors
|
|
ES2380473B1
(es)
*
|
2010-10-13 |
2013-02-19 |
Neuron Biopharma, S.A. |
Compuesto neuroprotector, hipocolesterolémico, antiinflamatorio y antiepiléptico.
|
|
US8258139B2
(en)
|
2010-11-08 |
2012-09-04 |
Dainippon Sumitomo Pharma Co., Ltd. |
Method of treatment for mental disorders
|
|
US8809345B2
(en)
|
2011-02-15 |
2014-08-19 |
Boehringer Ingelheim International Gmbh |
6-cycloalkyl-pyrazolopyrimidinones for the treatment of CNS disorders
|
|
CN103596955B
(zh)
*
|
2011-04-05 |
2016-11-16 |
索隆-基特林癌症研究协会 |
Hsp90抑制剂
|
|
JP6266506B2
(ja)
|
2011-04-05 |
2018-01-24 |
スローン − ケッタリング インスティチュート フォー キャンサー リサーチ |
Hsp90阻害物質
|
|
DK2721012T3
(en)
|
2011-06-17 |
2016-08-15 |
Lilly Co Eli |
Biclo (3.1.0) hexane-2,6-dicarboxylic acid derivatives as MGLU2 receptor agonist
|
|
EP2780015B1
(en)
|
2011-11-18 |
2017-01-04 |
Heptares Therapeutics Limited |
Muscarinic m1 receptor agonists
|
|
US20150141500A1
(en)
*
|
2012-05-10 |
2015-05-21 |
Mahesh Kandula |
Compositions and methods for the treatment of neurological diseases
|
|
US20150141384A1
(en)
*
|
2012-07-03 |
2015-05-21 |
Mahesh Kandula |
Compositions and methods for the treatment of neurological degenerative disorders
|
|
FR2993563B1
(fr)
*
|
2012-07-20 |
2015-12-18 |
Metabrain Res |
Derives de thiophenes utiles dans le traitement du diabete
|
|
CA2887598A1
(en)
|
2012-10-12 |
2014-04-17 |
Takeda Pharmaceutical Company Limited |
Cyclopropanamine compound and use thereof
|
|
RS58700B1
(sr)
|
2012-10-12 |
2019-06-28 |
Broad Inst Inc |
Gsk3 inhibitori i postupci njihove primene
|
|
WO2014075676A1
(en)
*
|
2012-11-15 |
2014-05-22 |
V-Biotek Holding Aps |
Amines from trigonella foemum - graecum
|
|
EP2970312B1
(en)
*
|
2013-03-11 |
2017-11-15 |
The Regents of The University of Michigan |
Bet bromodomain inhibitors and therapeutic methods using the same
|
|
KR20160115936A
(ko)
*
|
2014-02-19 |
2016-10-06 |
하. 룬드벡 아크티에셀스카브 |
알츠하이머병의 치료를 위한 bace1 저해제로서의 2-아미노-3,5,5-트리플루오로-3,4,5,6-테트라하이드로피리딘
|
|
GB201404922D0
(en)
|
2014-03-19 |
2014-04-30 |
Heptares Therapeutics Ltd |
Pharmaceutical compounds
|
|
MY180575A
(en)
|
2014-04-11 |
2020-12-02 |
Takeda Pharmaceuticals Co |
Cyclopropanamine compound and use thereof
|
|
JP2015227329A
(ja)
*
|
2014-05-09 |
2015-12-17 |
サントリーホールディングス株式会社 |
メトキシフラボンを含むNOX阻害剤及びNFκB阻害剤
|
|
WO2015195950A1
(en)
*
|
2014-06-20 |
2015-12-23 |
Principia Biophamram Inc. |
Lmp7 inhibitors
|
|
ES2717510T3
(es)
*
|
2014-09-17 |
2019-06-21 |
Oncodesign Sa |
Inhibidores macrocíclicos de cinasa LRRK2
|
|
JO3458B1
(ar)
|
2014-11-10 |
2020-07-05 |
H Lundbeck As |
2- أمينو-6- (دايفلوروميثيل) – 5، 5- ديفلورو-6-فينيل-3،4، 5، 6-تيتراهيدروبيريدين كمثبطات bace1
|
|
MA40941A
(fr)
|
2014-11-10 |
2017-09-19 |
H Lundbeck As |
2-amino-5,5-difluoro-6-(fluorométhyl)-6-phényl-3,4,5,6-tétrahydropyridines comme inhibiteurs de bace1
|
|
CR20170187A
(es)
|
2014-11-10 |
2018-02-01 |
H Lundbeck As |
2-Amino-3,5-difluoro-6-metil-6-fenil-3,4,5,6-tetrahidropiridinas en calidad de inhibidores de BACE1 para el tratamiento de la enfermedad de Alzheimer
|
|
WO2016140879A1
(en)
*
|
2015-03-03 |
2016-09-09 |
Biohaven Pharmaceutical Holding Company Ltd. |
Riluzole prodrugs and their use
|
|
US10647679B2
(en)
*
|
2015-03-15 |
2020-05-12 |
Emory University |
N-methyl-D-aspartate receptor (NMDAR) potentiators, pharmaceutical compositions, and uses related thereto
|
|
AR105025A1
(es)
*
|
2015-06-19 |
2017-08-30 |
Astellas Pharma Inc |
Compuesto de imidazodiazepina
|
|
GB201513743D0
(en)
|
2015-08-03 |
2015-09-16 |
Heptares Therapeutics Ltd |
Muscarinic agonists
|
|
TW201717948A
(zh)
|
2015-08-10 |
2017-06-01 |
H 朗德貝克公司 |
包括給予2-胺基-3,5,5-三氟-3,4,5,6-四氫吡啶的聯合治療
|
|
EP3334720A1
(en)
|
2015-08-12 |
2018-06-20 |
H. Lundbeck A/S |
2-amino-3-fluoro-3-(fluoromethyl)-6-methyl-6-phenyl-3,4,5,6-tetrahydropyridins as bace1 inhibitors
|
|
GB201519352D0
(en)
|
2015-11-02 |
2015-12-16 |
Heptares Therapeutics Ltd |
Pharmaceutical compounds
|
|
MA45599A
(fr)
*
|
2016-07-11 |
2019-05-15 |
Sage Therapeutics Inc |
Stéroïdes neuroactifs substitués en c17, c20 et c21 et leurs procédés d'utilisation
|
|
EP3493803A4
(en)
*
|
2016-08-05 |
2020-04-22 |
The Regents of The University of California |
GP130 MODULATORS
|
|
SMT202200331T1
(it)
*
|
2016-10-05 |
2022-09-14 |
Nsc Therapeutics Gmbh |
Polimorfi cristallini di un agonista di recettore muscarinico di acetilcolina
|
|
GB201617454D0
(en)
|
2016-10-14 |
2016-11-30 |
Heptares Therapeutics Limited |
Pharmaceutical compounds
|
|
US20190388425A1
(en)
*
|
2017-01-20 |
2019-12-26 |
Bayer Pharma Aktiengesellschaft |
Substituted imidazopyridinpyrimidines
|
|
WO2018167176A1
(en)
*
|
2017-03-15 |
2018-09-20 |
Ucb Biopharma Sprl |
Fused pentacyclic imidazole derivatives as modulators of tnf activity
|
|
CA3058198A1
(en)
*
|
2017-04-05 |
2018-10-11 |
The Broad Institute, Inc. |
Tricyclic compounds as glycogen synthase kinase 3 (gsk3) inhibitors and uses thereof
|
|
EP3625232B1
(en)
*
|
2017-05-19 |
2021-06-23 |
Council of Scientific and Industrial Research |
Substituted methanopyrido [2, 1-a]isoindolones as machr modulators for treating various associated pathophysiological conditions and process for preparation thereof
|
|
GB201712567D0
(en)
*
|
2017-08-04 |
2017-09-20 |
Karin & Sten Mortstedt Cbd Solutions Ab |
Selective ligands for tau aggregates
|
|
GB201810239D0
(en)
|
2018-06-22 |
2018-08-08 |
Heptares Therapeutics Ltd |
Pharmaceutical compounds
|
|
GB201819960D0
(en)
|
2018-12-07 |
2019-01-23 |
Heptares Therapeutics Ltd |
Pharmaceutical compounds
|
|
GB201819961D0
(en)
|
2018-12-07 |
2019-01-23 |
Heptares Therapeutics Ltd |
Pharmaceutical compounds
|
|
GB202020191D0
(en)
|
2020-12-18 |
2021-02-03 |
Heptares Therapeutics Ltd |
Pharmaceutical compounds
|
|
WO2021123883A1
(en)
*
|
2019-12-19 |
2021-06-24 |
Latvian Institute Of Organic Synthesis |
Macrocyclic amides acting as plasmepsin inhbitors for the treatment of malaria
|
|
US20240382488A1
(en)
*
|
2021-03-29 |
2024-11-21 |
Halia Therapeutics, Inc. |
Nek7 inhibitors
|