BR0209850A - Método para produzir biperideno, e, composto - Google Patents

Método para produzir biperideno, e, composto

Info

Publication number
BR0209850A
BR0209850A BR0209850-4A BRPI0209850A BR0209850A BR 0209850 A BR0209850 A BR 0209850A BR PI0209850 A BRPI0209850 A BR PI0209850A BR 0209850 A BR0209850 A BR 0209850A
Authority
BR
Brazil
Prior art keywords
biperiden
compound
producing
exo
endo
Prior art date
Application number
BR0209850-4A
Other languages
English (en)
Inventor
Gerhard Kastner
Klaus Scheib
Original Assignee
Abbott Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2001124450 external-priority patent/DE10124450A1/de
Priority claimed from DE2001124452 external-priority patent/DE10124452A1/de
Application filed by Abbott Gmbh & Co Kg filed Critical Abbott Gmbh & Co Kg
Publication of BR0209850A publication Critical patent/BR0209850A/pt
Publication of BRPI0209850B1 publication Critical patent/BRPI0209850B1/pt
Publication of BRPI0209850B8 publication Critical patent/BRPI0209850B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

"MéTODO PARA PRODUZIR BIPERIDENO, E, COMPOSTO". A invenção refere-se a um método para a produção de biperideno que é caracterizado em que uma mistura exo/endo de 1- (biciclo [2.2.1.] hept-5-en-2-il) -3-piperidino- 1-propanona é reagida com uma relação de isómero da forma exo para a forma endo de pelo menos 2,5:1 com difenil magnésio, uma mistura de isómeros contendo biperideno é obtida a partir dai e biperideno é produzido assim.
BRPI0209850-4 2001-05-18 2002-05-17 método para produzir biperideno BRPI0209850B8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE2001124450 DE10124450A1 (de) 2001-05-18 2001-05-18 Verfahren zur Herstellung von Biperiden
DE2001124452 DE10124452A1 (de) 2001-05-18 2001-05-18 Verfahren zur Herstellung von Biperiden
DE10124452.5 2001-05-18
DE10124450.9 2001-05-18
PCT/EP2002/005498 WO2002094801A1 (de) 2001-05-18 2002-05-17 Verfahren zur herstellung von biperiden i

Publications (3)

Publication Number Publication Date
BR0209850A true BR0209850A (pt) 2004-06-15
BRPI0209850B1 BRPI0209850B1 (pt) 2018-05-15
BRPI0209850B8 BRPI0209850B8 (pt) 2021-05-25

Family

ID=26009342

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0209850-4 BRPI0209850B8 (pt) 2001-05-18 2002-05-17 método para produzir biperideno

Country Status (12)

Country Link
US (1) US7034158B2 (pt)
EP (1) EP1389193B1 (pt)
JP (1) JP4338979B2 (pt)
KR (1) KR100896836B1 (pt)
CN (1) CN1281594C (pt)
AT (1) ATE307124T1 (pt)
BR (1) BRPI0209850B8 (pt)
DE (1) DE50204608D1 (pt)
DK (1) DK1389193T3 (pt)
ES (1) ES2250678T3 (pt)
IL (2) IL158932A0 (pt)
WO (1) WO2002094801A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5861884B2 (ja) * 2012-03-29 2016-02-16 荒川化学工業株式会社 エキソ型ノルボルネン化合物の製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2789110A (en) * 1953-03-14 1957-04-16 Knoll Ag Amino alcohols substituted by bicycloalkyl residues and a process of making same
DE1005067B (de) * 1953-03-14 1957-03-28 Knoll Ag Verfahren zur Herstellung von bicyclisch substituierten Aminopropanolen
JPH11189729A (ja) 1997-12-26 1999-07-13 Chemiprokasei Kaisha Ltd 色素兼紫外線安定剤およびそれを含む高分子組成物
DE10124449A1 (de) * 2001-05-18 2002-11-21 Abbott Gmbh & Co Kg Verfahren zur Herstellung von Biperiden
DE10124451A1 (de) 2001-05-18 2002-11-21 Abbott Gmbh & Co Kg Verfahren zur Herstellung von Biperiden

Also Published As

Publication number Publication date
WO2002094801A1 (de) 2002-11-28
KR100896836B1 (ko) 2009-05-12
DK1389193T3 (da) 2006-03-06
DE50204608D1 (de) 2006-03-02
KR20040007578A (ko) 2004-01-24
CN1281594C (zh) 2006-10-25
BRPI0209850B1 (pt) 2018-05-15
US7034158B2 (en) 2006-04-25
EP1389193B1 (de) 2005-10-19
JP4338979B2 (ja) 2009-10-07
ATE307124T1 (de) 2005-11-15
CN1525963A (zh) 2004-09-01
ES2250678T3 (es) 2006-04-16
IL158932A (en) 2009-12-24
IL158932A0 (en) 2004-05-12
JP2004536068A (ja) 2004-12-02
US20050176963A1 (en) 2005-08-11
BRPI0209850B8 (pt) 2021-05-25
EP1389193A1 (de) 2004-02-18

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: PARA INT.CL: C07D 295/08, C07D 295/10, A61P 25/00

Ipc: C07D 295/08 (2011.01), C07D 295/10 (2011.01)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]
B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 17/05/2002 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 21A ANUIDADE.

B21H Decision of lapse of a patent or of a certificate of addition of invention cancelled [chapter 21.8 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 21.6 NA RPI NO 2723 DE 14/03/2023 POR TER SIDO INDEVIDA.

B21A Patent or certificate of addition expired [chapter 21.1 patent gazette]

Free format text: PATENTE EXTINTA EM 17/05/2022