BR0113350A - Aminoalquenilbenzoil-benzofuranos ou benzotiofenos, seu processo de preparação e as composições que os contêm - Google Patents
Aminoalquenilbenzoil-benzofuranos ou benzotiofenos, seu processo de preparação e as composições que os contêmInfo
- Publication number
- BR0113350A BR0113350A BR0113350-0A BR0113350A BR0113350A BR 0113350 A BR0113350 A BR 0113350A BR 0113350 A BR0113350 A BR 0113350A BR 0113350 A BR0113350 A BR 0113350A
- Authority
- BR
- Brazil
- Prior art keywords
- aminoalkenylbenzoylbenzofurans
- benzothiophenes
- preparation process
- compositions containing
- benzotiophenes
- Prior art date
Links
- FCEHBMOGCRZNNI-UHFFFAOYSA-N 1-benzothiophene Chemical class C1=CC=C2SC=CC2=C1 FCEHBMOGCRZNNI-UHFFFAOYSA-N 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 210000000748 cardiovascular system Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0010835A FR2813307B1 (fr) | 2000-08-23 | 2000-08-23 | Aminoalkenylbenzoyl-benzofurannes ou benzothiophenes, leur procede de preparation et les compositions les contenant |
PCT/FR2001/002656 WO2002016338A1 (fr) | 2000-08-23 | 2001-08-23 | Aminoalkenylbenzoyl-benzofuranes ou benzothiophenes, leur procede de preparation et les compositions les contenant |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0113350A true BR0113350A (pt) | 2003-07-08 |
Family
ID=8853675
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0113350-0A BR0113350A (pt) | 2000-08-23 | 2001-08-23 | Aminoalquenilbenzoil-benzofuranos ou benzotiofenos, seu processo de preparação e as composições que os contêm |
Country Status (25)
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2387563B2 (en) | 2009-01-16 | 2022-04-27 | Exelixis, Inc. | Malate salt of n- (4- { [ 6, 7-bis (methyloxy) quinolin-4-yl]oxy}phenyl-n' - (4 -fluorophenyl) cyclopropane-1,1-dicarboxamide, and crystalline forms thereof for the treatment of cancer |
AU2011202542A1 (en) | 2010-07-14 | 2012-02-02 | Indian Institute Of Science | Benzothiophene carboxamide compounds, composition and applications thereof |
CN107857748B (zh) * | 2017-11-14 | 2020-06-02 | 沈阳药科大学 | 5-[2-羟基-3-(烷胺基)丙氧基]苯并呋喃类化合物及其应用 |
CN107827849B (zh) * | 2017-11-14 | 2020-06-02 | 沈阳药科大学 | 6-[2-羟基-3-(烷胺基)丙氧基]苯并呋喃类化合物及其应用 |
CN107935972B (zh) * | 2017-11-14 | 2020-06-02 | 沈阳药科大学 | 5-[2-羟基-3-(异丙胺基)丙氧基]苯并呋喃类衍生物及其应用 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3248401A (en) * | 1966-04-26 | Diethylaminoe hoxybenzoyl benzofurans | ||
US4831054A (en) * | 1988-04-18 | 1989-05-16 | Taro Pharmaceuticals, Ltd. | 2-Alkyl-3-benzoylbenzofurans useful for treating cardiac arrhythmia |
AT391316B (de) * | 1988-09-15 | 1990-09-25 | Ebewe Arzneimittel | Neue thienyloxy-alkylamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
FR2665444B1 (fr) * | 1990-08-06 | 1992-11-27 | Sanofi Sa | Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant. |
US5364880A (en) * | 1993-06-16 | 1994-11-15 | Advanced Therapies, Inc. | Compound for treatment of cardiac arrhythmia, synthesis, and methods of use |
US6756388B1 (en) * | 1993-10-12 | 2004-06-29 | Pfizer Inc. | Benzothiophenes and related compounds as estrogen agonists |
US5622974A (en) * | 1995-03-10 | 1997-04-22 | Eli Lilly And Company | α-substituted-3-benzyl-benzofurans |
US5523309A (en) * | 1995-03-10 | 1996-06-04 | Eli Lilly And Company | Benzofuran pharmaceutical compounds |
AU6335496A (en) * | 1995-06-26 | 1997-01-30 | Eli Lilly And Company | Benzothiophene compounds |
US5827876A (en) * | 1996-04-09 | 1998-10-27 | American Home Products Corporation | Inhibition of bone loss by 3-(4-acrylamidobenzoyl) benzo b!-thiophenes |
WO1999054325A1 (fr) * | 1998-04-17 | 1999-10-28 | Senga Pharmaceutical Laboratory Inc. | Derives 1-heteroindene et compositions medicinales a base de tels derives |
-
2000
- 2000-08-23 FR FR0010835A patent/FR2813307B1/fr not_active Expired - Fee Related
-
2001
- 2001-08-23 DE DE60104866T patent/DE60104866T2/de not_active Expired - Lifetime
- 2001-08-23 AU AU2001284154A patent/AU2001284154A1/en not_active Abandoned
- 2001-08-23 EA EA200300063A patent/EA200300063A1/ru unknown
- 2001-08-23 WO PCT/FR2001/002656 patent/WO2002016338A1/fr not_active Application Discontinuation
- 2001-08-23 CN CNA018177654A patent/CN1471519A/zh active Pending
- 2001-08-23 CA CA002415846A patent/CA2415846A1/fr not_active Abandoned
- 2001-08-23 HU HU0302892A patent/HUP0302892A3/hu unknown
- 2001-08-23 JP JP2002521439A patent/JP4918209B2/ja not_active Expired - Fee Related
- 2001-08-23 EP EP01963120A patent/EP1315708B1/fr not_active Expired - Lifetime
- 2001-08-23 CZ CZ2003520A patent/CZ2003520A3/cs unknown
- 2001-08-23 PL PL01362123A patent/PL362123A1/xx not_active Application Discontinuation
- 2001-08-23 MX MXPA03001592A patent/MXPA03001592A/es not_active Application Discontinuation
- 2001-08-23 OA OA1200300034A patent/OA12358A/fr unknown
- 2001-08-23 US US10/362,291 patent/US6946483B2/en not_active Expired - Lifetime
- 2001-08-23 SK SK211-2003A patent/SK2112003A3/sk unknown
- 2001-08-23 AT AT01963120T patent/ATE273293T1/de not_active IP Right Cessation
- 2001-08-23 KR KR10-2003-7002619A patent/KR20030023768A/ko not_active Application Discontinuation
- 2001-08-23 BR BR0113350-0A patent/BR0113350A/pt not_active IP Right Cessation
- 2001-08-23 IL IL15363701A patent/IL153637A0/xx unknown
-
2003
- 2003-01-13 IS IS6676A patent/IS6676A/is unknown
- 2003-01-28 ZA ZA200300746A patent/ZA200300746B/xx unknown
- 2003-02-13 BG BG107553A patent/BG107553A/xx unknown
- 2003-02-17 MA MA27043A patent/MA26944A1/fr unknown
- 2003-02-20 NO NO20030801A patent/NO20030801L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
KR20030023768A (ko) | 2003-03-19 |
WO2002016338A8 (fr) | 2002-05-10 |
CA2415846A1 (fr) | 2002-02-28 |
WO2002016338A1 (fr) | 2002-02-28 |
HUP0302892A3 (en) | 2005-02-28 |
JP2004506726A (ja) | 2004-03-04 |
ATE273293T1 (de) | 2004-08-15 |
DE60104866T2 (de) | 2005-10-20 |
PL362123A1 (en) | 2004-10-18 |
CN1471519A (zh) | 2004-01-28 |
MA26944A1 (fr) | 2004-12-20 |
ZA200300746B (en) | 2004-02-10 |
JP4918209B2 (ja) | 2012-04-18 |
SK2112003A3 (en) | 2003-08-05 |
AU2001284154A1 (en) | 2002-03-04 |
US6946483B2 (en) | 2005-09-20 |
NO20030801L (no) | 2003-04-23 |
HUP0302892A2 (hu) | 2003-12-29 |
MXPA03001592A (es) | 2003-09-10 |
FR2813307A1 (fr) | 2002-03-01 |
DE60104866D1 (de) | 2004-09-16 |
NO20030801D0 (no) | 2003-02-20 |
EA200300063A1 (ru) | 2003-08-28 |
IL153637A0 (en) | 2003-07-06 |
IS6676A (is) | 2003-01-13 |
CZ2003520A3 (cs) | 2003-05-14 |
EP1315708A1 (fr) | 2003-06-04 |
US20030187060A1 (en) | 2003-10-02 |
OA12358A (fr) | 2006-05-16 |
EP1315708B1 (fr) | 2004-08-11 |
FR2813307B1 (fr) | 2002-11-08 |
BG107553A (en) | 2004-01-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5A,6AE7A ANUIDADE |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1963 DE 19.08.2008. |