BR0112826A - Derivados da oxazolidinona como antimicrobianos - Google Patents

Derivados da oxazolidinona como antimicrobianos

Info

Publication number
BR0112826A
BR0112826A BR0112826-4A BR0112826A BR0112826A BR 0112826 A BR0112826 A BR 0112826A BR 0112826 A BR0112826 A BR 0112826A BR 0112826 A BR0112826 A BR 0112826A
Authority
BR
Brazil
Prior art keywords
spp
mycobacterium
compounds
oxazolidinone derivatives
relates
Prior art date
Application number
BR0112826-4A
Other languages
English (en)
Inventor
Anita Metha
Sudershan K Arora
Biswajit Das
Abhijit Ray
Sonali Rudra
Ashok Rattan
Original Assignee
Ranbaxy Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Lab Ltd filed Critical Ranbaxy Lab Ltd
Publication of BR0112826A publication Critical patent/BR0112826A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

"DERIVADOS DA OXAZOLIDINONA COMO ANTIMICROBIANOS". A presente invenção se relaciona com determinadas fenil oxazolidinonas substituídas e os processos de síntese das mesmas. Esta invenção também se refere a composições farmacêuticas antimicrobianas contendo os compostos da presente invenção. Os compostos são úteis como agentes antimicrobianos, efetivo contra muitos patógenos para humanos e animais, incluindo bactérias aeróbicas gram-positivas tais como estafilococos multiresistente, estreptococos e enterococos bem como organismos anaeróbicos tal como Bacterioides spp. e Clostridia spp., e organismos tais como Mycobacterium tuberculosis, Mycobacterium avium e Mycobacterium spp.
BR0112826-4A 2000-07-17 2001-07-16 Derivados da oxazolidinona como antimicrobianos BR0112826A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN654DE2000 2000-07-17
PCT/IB2001/001262 WO2002006278A1 (en) 2000-07-17 2001-07-16 Oxazolidinone derivatives as antimicrobials

Publications (1)

Publication Number Publication Date
BR0112826A true BR0112826A (pt) 2003-06-24

Family

ID=11097070

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0112826-4A BR0112826A (pt) 2000-07-17 2001-07-16 Derivados da oxazolidinona como antimicrobianos

Country Status (16)

Country Link
US (2) US6734307B2 (pt)
EP (1) EP1303511A1 (pt)
JP (1) JP2004504321A (pt)
CN (1) CN1447808A (pt)
AU (2) AU2001269370B2 (pt)
BR (1) BR0112826A (pt)
CA (1) CA2415965A1 (pt)
CZ (1) CZ2003228A3 (pt)
HU (1) HUP0302918A2 (pt)
MX (1) MXPA03000503A (pt)
NZ (1) NZ523700A (pt)
PL (1) PL363960A1 (pt)
RU (1) RU2292345C9 (pt)
SK (1) SK1402003A3 (pt)
WO (1) WO2002006278A1 (pt)
ZA (1) ZA200300471B (pt)

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US20070293493A1 (en) * 2003-07-02 2007-12-20 Milton Hammond Oxazolidinone antibiotics and derivatives thereof
CA2529293A1 (en) * 2003-07-02 2005-01-20 Merck & Co., Inc. Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof
GB0324269D0 (en) 2003-10-16 2003-11-19 Pharmagene Lab Ltd EP4 receptor antagonists
WO2005051933A1 (en) * 2003-11-28 2005-06-09 Ranbaxy Laboratories Limited An improved process for the synthesis of 4-(4-benzyloxy-carbonylamino-2-fluorophenyl)-piperazine-1-carboxylic acid tert-butyl ester, a key intermediate for oxazolidinone antimicrobials and compounds prepared thereby
WO2005082899A1 (en) * 2004-01-28 2005-09-09 Ranbaxy Laboratories Limited Oxazolidinone derivatives as antimicrobials
EP1802613A1 (en) * 2004-10-11 2007-07-04 Ranbaxy Laboratories Limited Substituted oxazolidinone derivatives
ATE449773T1 (de) 2005-06-29 2009-12-15 Pharmacia & Upjohn Co Llc Homomorpholinoxazolidinone als antibakterielle mittel
FR2895735B1 (fr) 2005-12-30 2008-04-18 Ecopack France Valve a poche amelioree
US7728031B2 (en) 2006-02-24 2010-06-01 Abbott Laboratories Octahydro-pyrrolo[3,4-b]pyrrole derivatives
CN101460495B (zh) 2006-03-31 2013-08-14 财团法人乙卯研究所 具有杂环的化合物
JP5665540B2 (ja) 2007-09-11 2015-02-04 アッヴィ・インコーポレイテッド オクタヒドロ−ピロロ［３，４−ｂ］ピロールｎ−オキシド
EP2233484A3 (en) 2007-10-02 2012-04-04 Research Foundation Itsuu Laboratory Oxazolidinone derivatives having a 7-membered heterocyclic ring
WO2009132310A1 (en) * 2008-04-25 2009-10-29 Wisconsin Alumni Research Foundation Inhibitors of udp-galactopyranose mutase thwart mycobacterial growth
JP2014500247A (ja) 2010-11-03 2014-01-09 ウォックハート リミテッド リン酸モノ−（１−｛４−［（ｓ）―５−（アセチルアミノメチル）−２−オキソ−オキサゾリジン−３−イル］−２，６−ジフルオロフェニル｝−４−メトキシメチルピペリジン−４−イル）エステルの調製方法
JP5796134B2 (ja) * 2011-09-29 2015-10-21 山東軒竹医薬科技有限公司 ビアリールヘテロ環で置換されたオキサゾリドン抗菌薬
WO2015173664A1 (en) 2014-05-14 2015-11-19 Wockhardt Limited Process for the preparation of (5s)-n-{3-[3,5-difluoro-4-(4-hydroxy-4-methoxymethyl-piperidin-1-yl)-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide
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CN109020873B (zh) * 2018-07-16 2020-04-28 青岛农业大学 以靶标蛋白甾醇14α-脱甲基酶三维结构筛选的化合物及其在在制备杀菌剂中的应用
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Also Published As

Publication number Publication date
EP1303511A1 (en) 2003-04-23
CZ2003228A3 (cs) 2003-06-18
US20040242591A1 (en) 2004-12-02
ZA200300471B (en) 2003-10-29
JP2004504321A (ja) 2004-02-12
WO2002006278A1 (en) 2002-01-24
NZ523700A (en) 2004-11-26
CA2415965A1 (en) 2002-01-24
RU2292345C2 (ru) 2007-01-27
RU2292345C9 (ru) 2007-05-10
HUP0302918A2 (hu) 2003-12-29
US20020103186A1 (en) 2002-08-01
SK1402003A3 (en) 2003-08-05
AU6937001A (en) 2002-01-30
AU2001269370B2 (en) 2005-10-27
PL363960A1 (en) 2004-11-29
US6734307B2 (en) 2004-05-11
CN1447808A (zh) 2003-10-08
MXPA03000503A (es) 2003-10-14

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6O, 7O E 8O ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2021 DE 29/09/2009.