BR0011815A - Processo para a purificação de poloxâmeros que contêm impurezas de aldeìdo, e, poloxâmero - Google Patents

Processo para a purificação de poloxâmeros que contêm impurezas de aldeìdo, e, poloxâmero

Info

Publication number
BR0011815A
BR0011815A BR0011815-0A BR0011815A BR0011815A BR 0011815 A BR0011815 A BR 0011815A BR 0011815 A BR0011815 A BR 0011815A BR 0011815 A BR0011815 A BR 0011815A
Authority
BR
Brazil
Prior art keywords
poloxamer
purification
poloxamers
aldehyde impurities
solvent
Prior art date
Application number
BR0011815-0A
Other languages
English (en)
Other versions
BR0011815B1 (pt
Inventor
Mats Berg
Alf Djurle
Magnus Melin
Peter Nyman
Original Assignee
Dentsply Anesthetics S A R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dentsply Anesthetics S A R L filed Critical Dentsply Anesthetics S A R L
Publication of BR0011815A publication Critical patent/BR0011815A/pt
Publication of BR0011815B1 publication Critical patent/BR0011815B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/30—Post-polymerisation treatment, e.g. recovery, purification, drying

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polyethers (AREA)

Abstract

"PROCESSO PARA A PURIFICAçãO DE POLOXâMEROS QUE CONTêM IMPUREZAS DE ALDEìDO, E, POLOXâMERO". Novo processo para a purificação de poloxâmeros que contêm impurezas de aldeído, e particularmente para a purificação dos poloxâmeros denominados poloxâmero 188 e poloxâmero 407, cujo processo inclui dissolver o poloxâmero(s) em solvente cujo solvente pode conter opcionalmente ácido ou mistura de ácidos; se o solvente em que o poloxâmero(s) foi dissolvido é livre de ácido, ácido é adicionado; após o qual os aldeídos são removidos.
BRPI0011815-0A 1999-06-21 2000-06-19 processo para a purificação de poloxámeros que contêm impurezas de aldeìdo. BR0011815B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9902364A SE9902364D0 (sv) 1999-06-21 1999-06-21 New process
PCT/SE2000/001305 WO2000078841A1 (en) 1999-06-21 2000-06-19 New process for the purification of aldehyde impurities
US09/656,036 US6448371B1 (en) 1999-06-21 2000-09-08 Process for the purification of aldehyde impurities

Publications (2)

Publication Number Publication Date
BR0011815A true BR0011815A (pt) 2002-03-19
BR0011815B1 BR0011815B1 (pt) 2010-06-15

Family

ID=26663601

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0011815-0A BR0011815B1 (pt) 1999-06-21 2000-06-19 processo para a purificação de poloxámeros que contêm impurezas de aldeìdo.

Country Status (18)

Country Link
US (1) US6448371B1 (pt)
EP (1) EP1192204B1 (pt)
JP (1) JP2003503517A (pt)
CN (1) CN1139615C (pt)
AT (1) ATE312863T1 (pt)
AU (1) AU765560B2 (pt)
BR (1) BR0011815B1 (pt)
CA (1) CA2377004A1 (pt)
DE (1) DE60024821T2 (pt)
DK (1) DK1192204T3 (pt)
ES (1) ES2254200T3 (pt)
IL (1) IL146746A0 (pt)
MX (1) MXPA01013369A (pt)
NO (1) NO318915B1 (pt)
NZ (1) NZ515954A (pt)
SE (1) SE9902364D0 (pt)
WO (1) WO2000078841A1 (pt)
ZA (1) ZA200109740B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040266983A1 (en) * 2000-08-17 2004-12-30 Reeve Lorraine E Purified polyoxyalkylene block copolymers
WO2002088217A1 (en) * 2001-05-01 2002-11-07 Union Carbide Chemicals & Plastics Technology Corporation Poly(alkylene oxides) having reduced amounts of formic compounds
EP1503732B1 (en) * 2002-04-29 2008-10-08 Alza Corporation Reduced formate poly(alkylene oxides) with reboxetine for reducing impurity formation
JP2005343964A (ja) * 2004-06-01 2005-12-15 Otsuka Pharmaceut Factory Inc ポリアルキレングリコール類含有水溶液、及びその調製方法
KR101343040B1 (ko) * 2010-12-28 2013-12-18 주식회사 삼양바이오팜 정제된 폴록사머 및 그의 정제방법
JP2013237638A (ja) * 2012-05-15 2013-11-28 Lion Corp 眼科組成物
AU2015287993B2 (en) 2014-07-07 2020-10-29 Liferaft Biosciences, Inc. A poloxamer composition free of long circulating material and methods for production and uses thereof
WO2017108457A1 (en) 2015-12-22 2017-06-29 Basf Se A process for purification of polyether block copolymers
CN110139887B (zh) * 2017-01-06 2022-03-08 三洋化成工业株式会社 聚醚多元醇的制造方法和聚氨酯泡沫的制造方法
US20200010618A1 (en) 2017-02-09 2020-01-09 Basf Se A process for purification of polyether block copolymers
US20210163879A1 (en) 2017-12-20 2021-06-03 Basf Se A method for stabilizing cell culture systems using an amphiphilic graft copolymer as cell culture reagent

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3036130A (en) * 1957-09-10 1962-05-22 Wyandotte Chemicals Corp Mixtures of novel conjugated polyoxyethylene-polyoxypropylene compounds
US3462379A (en) * 1965-12-02 1969-08-19 Dow Chemical Co Purification of poly(alkylene oxides)
US3546321A (en) * 1967-02-08 1970-12-08 Hercules Inc Polyether graft copolymers
US3639574A (en) * 1967-10-25 1972-02-01 Basf Wyandotte Corp Stable hydrogen peroxide gels
US3715402A (en) * 1969-08-08 1973-02-06 Basf Wyandotte Corp Removal of catalysts from polyols
US3674502A (en) * 1969-09-05 1972-07-04 Firmenich Inc Nonringing beverages containing poly(oxyethylene) - poly(oxypropylene) - poly(oxyethylene) copolymers
DE2755089C3 (de) * 1977-12-10 1982-05-13 Bayer Ag, 5090 Leverkusen Verfahren zur Reinigung von Rohpolyäthern
DE2854541A1 (de) * 1978-12-16 1980-06-26 Bayer Ag Verfahren zur reinigung nichtionischer emulgatoren
US4410447A (en) * 1980-11-12 1983-10-18 Union Carbide Corporation Low-foaming nonionic surfactants
US4606918A (en) * 1983-08-22 1986-08-19 Syntex (U.S.A.) Inc. Polyoxypropylene-polyoxyethylene block polymer based adjuvants
US5342541A (en) * 1989-03-29 1994-08-30 The Dow Chemical Company Purified hydroxy-functional polyether compounds
DE3913937A1 (de) * 1989-04-27 1990-10-31 Hoechst Ag Verfahren zur reinigung von alkylenoxid-addukten
JPH0791389B2 (ja) * 1989-05-17 1995-10-04 信越化学工業株式会社 精製されたポリエーテルシリコーン及びその製造方法
US5095061A (en) * 1990-07-13 1992-03-10 The Dow Chemical Company Process to reduce propenyl polyethers in hydroxyfunctional polyethers
US5268510A (en) * 1992-10-08 1993-12-07 Vista Chemical Company Process for purification of alkoxylated alcohols
KR0145350B1 (ko) * 1993-09-07 1998-07-15 사또오 아키오 폴리옥시알킬렌폴리올의 제조방법
CA2174394A1 (en) * 1995-06-12 1996-12-13 Timothy L. Lambert Process for preparing low unsaturation polyether polyols
US6166266A (en) * 1998-11-12 2000-12-26 Bp Amoco Corporation Preparation of polyoxymethylene dimethyl ethers by catalytic conversion of dimethyl ether with formaldehyde formed by oxidation of methanol

Also Published As

Publication number Publication date
IL146746A0 (en) 2002-07-25
ZA200109740B (en) 2003-03-03
AU6034300A (en) 2001-01-09
NZ515954A (en) 2003-05-30
NO318915B1 (no) 2005-05-23
MXPA01013369A (es) 2002-07-30
ES2254200T3 (es) 2006-06-16
EP1192204B1 (en) 2005-12-14
WO2000078841A1 (en) 2000-12-28
CA2377004A1 (en) 2000-12-28
DE60024821T2 (de) 2006-06-14
AU765560B2 (en) 2003-09-25
JP2003503517A (ja) 2003-01-28
NO20016297D0 (no) 2001-12-20
NO20016297L (no) 2002-02-04
US6448371B1 (en) 2002-09-10
SE9902364D0 (sv) 1999-06-21
CN1357019A (zh) 2002-07-03
DK1192204T3 (da) 2006-02-20
EP1192204A1 (en) 2002-04-03
BR0011815B1 (pt) 2010-06-15
CN1139615C (zh) 2004-02-25
ATE312863T1 (de) 2005-12-15
DE60024821D1 (de) 2006-01-19

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 19/06/2000, OBSERVADAS AS CONDICOES LEGAIS.

B21A Patent or certificate of addition expired [chapter 21.1 patent gazette]

Free format text: PATENTE EXTINTA EM 19.06.2020