BR0011678A - Composições farmacêuticas compreendendo complexos de metal - Google Patents
Composições farmacêuticas compreendendo complexos de metalInfo
- Publication number
- BR0011678A BR0011678A BR0011678-5A BR0011678A BR0011678A BR 0011678 A BR0011678 A BR 0011678A BR 0011678 A BR0011678 A BR 0011678A BR 0011678 A BR0011678 A BR 0011678A
- Authority
- BR
- Brazil
- Prior art keywords
- group
- mixture
- pharmaceutical compositions
- metal complexes
- ions
- Prior art date
Links
- 229910052751 metal Inorganic materials 0.000 title abstract 2
- 239000002184 metal Substances 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 5
- 239000003446 ligand Substances 0.000 abstract 4
- -1 pseudohalide ion Chemical class 0.000 abstract 3
- 150000001768 cations Chemical group 0.000 abstract 2
- 229910021480 group 4 element Inorganic materials 0.000 abstract 2
- 229910021478 group 5 element Inorganic materials 0.000 abstract 2
- 229910021476 group 6 element Inorganic materials 0.000 abstract 2
- 229910021645 metal ion Inorganic materials 0.000 abstract 2
- 230000000737 periodic effect Effects 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F19/00—Metal compounds according to more than one of main groups C07F1/00 - C07F17/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0046—Ruthenium compounds
- C07F15/0053—Ruthenium compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/295—Iron group metal compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Patente de Invenção: "COMPOSIçõES FARMACêUTICAS COMPREENDENDO COMPLEXOS DE METAL". Um composto de fórmula [M~ a~(X~ b~L)~ c~Y~ d~Z~ e~]^ nt<sym>^ em que: M é um íon de metal ou uma mistura de íons de metal; X é um cátion ou uma mistura de cátions; L é um ligando ou mistura de ligandos, cada um contendo pelo menos dois átomos doadores diferentes selecionados dos elementos do Grupo IV, Grupo V ou Grupo VI da Tabela Periódica; Y é um ligando ou uma mistura dos mesmos ou de ligandos diferentes, cada um contendo pelo menos um átomo doador ou mais do que um átomo doador, selecionado dos elementos do Grupo IV, Grupo V ou Grupo VI da Tabela Periódica; e Z é um íon de haleto ou pseudo-haleto ou uma mistura de íons de haleto e íons de pseudo-haleto; e em que: a = 1-3; b = 0-12; c = 0-18; d = 0-18; e = 0-18; e n = 0-10; contanto que pelo menos um de c, d e e seja 1 ou mais; em que c é 0: b também é 0; em que a é 1: c, d e e não são maiores do que 9; e em que a é 2: c, d e e não são maiores do que 12.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12516699P | 1999-03-19 | 1999-03-19 | |
PCT/CA2000/000294 WO2000056743A1 (en) | 1999-03-19 | 2000-03-17 | Pharmaceutical compositions comprising metal complexes |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0011678A true BR0011678A (pt) | 2002-02-26 |
Family
ID=22418482
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0011678-5A BR0011678A (pt) | 1999-03-19 | 2000-03-17 | Composições farmacêuticas compreendendo complexos de metal |
Country Status (15)
Country | Link |
---|---|
US (1) | US20020049190A1 (pt) |
EP (1) | EP1163247A1 (pt) |
JP (1) | JP2004500321A (pt) |
KR (1) | KR20010112343A (pt) |
CN (1) | CN1391577A (pt) |
AU (1) | AU3268500A (pt) |
BR (1) | BR0011678A (pt) |
CA (1) | CA2367282A1 (pt) |
CZ (1) | CZ20013307A3 (pt) |
HU (1) | HUP0400457A2 (pt) |
IL (1) | IL145290A0 (pt) |
MX (1) | MXPA01009410A (pt) |
NO (1) | NO20014526L (pt) |
PL (1) | PL356683A1 (pt) |
WO (1) | WO2000056743A1 (pt) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CZ303156B6 (cs) | 1999-04-13 | 2012-05-09 | Anormed Inc. | Komplex cisplatiny a zpusob jeho prípravy |
JP4227701B2 (ja) * | 1999-05-25 | 2009-02-18 | 中部キレスト株式会社 | ジエチレントリアミン五酢酸ルテニウム二アンモニウム塩またはその水和物およびその製法 |
US6489638B2 (en) * | 2000-06-23 | 2002-12-03 | Semiconductor Energy Laboratory Co., Ltd. | Light emitting device |
US6894049B1 (en) | 2000-10-04 | 2005-05-17 | Anormed, Inc. | Platinum complexes as antitumor agents |
US20020072512A1 (en) * | 2000-12-08 | 2002-06-13 | Metaphore Pharmaceuticals, Inc | Method of preventing and treating HIV-mediated central nervous system damage |
GB0111872D0 (en) | 2001-05-15 | 2001-07-04 | Northwick Park Inst For Medica | Therapeutic agents and methods |
US7011854B2 (en) | 2002-02-04 | 2006-03-14 | Alfama-Investigacao e Desenvolvimento de Produtos Farmaceuticos Lda | Method for treating a mammal by administration of a compound having the ability to release CO, compounds having the ability to release CO and pharmaceutical compositions thereof |
GB2395432B (en) * | 2002-11-20 | 2005-09-14 | Northwick Park Inst For Medica | Therapeutic delivery of carbon monoxide to extracorporeal and isolated organs |
GB2395431A (en) * | 2002-11-20 | 2004-05-26 | Northwick Park Inst For Medica | Combination of a metal carbonyl compound and a guanylate cyclase stimulant or stabilizer for the therapeutic delivery of carbon monoxide |
ES2390457T3 (es) * | 2003-08-04 | 2012-11-13 | Johnson & Johnson Consumer Companies, Inc. | Métodos para el tratamiento de enfermedades dermatológicas |
NZ548440A (en) | 2004-02-05 | 2009-07-31 | Kyorin Seiyaku Kk | Bicycloester derivative inhibitng DPP-IV for treatment of diabetes or similar |
FR2873037B1 (fr) * | 2004-07-13 | 2008-04-11 | Univ Pasteur | Methodes et compositions pour le traitement de cancers |
MX2008008104A (es) * | 2005-12-21 | 2008-09-03 | Oxford Biosensors Ltd | Mediadores redox. |
GB0601394D0 (en) | 2006-01-24 | 2006-03-01 | Hemocorm Ltd | Therapeutic delivery of carbon monoxide |
CN101395131B (zh) | 2006-03-08 | 2012-11-14 | 杏林制药株式会社 | 氨基乙酰基吡咯烷甲腈衍生物的制备方法及其制备中间体 |
CA2655933C (en) | 2006-06-23 | 2014-09-09 | Alethia Biotherapeutics Inc. | Polynucleotides and polypeptide sequences involved in cancer |
WO2008038305A2 (en) * | 2006-09-26 | 2008-04-03 | Jegannathan Srinivas | Therapeutical formulation comprising a thiazolidinedione and a nitric oxide scavenger. |
WO2008114857A1 (ja) | 2007-03-22 | 2008-09-25 | Kyorin Pharmaceutical Co., Ltd. | アミノアセチルピロリジンカルボニトリル誘導体の製造方法 |
CA3050455A1 (en) | 2008-11-03 | 2010-06-03 | Adc Therapeutics Sa | Antibodies that specifically block the biological activity of a tumor antigen |
DE102010014412A1 (de) | 2010-04-08 | 2012-04-19 | Friedrich-Schiller-Universität Jena | Verwendung von zweikernigen Eisenkomplexen mit schwefelhaltigen Liganden als pharmakologische Wirkstoffe |
DE102010014411A1 (de) | 2010-04-08 | 2011-10-13 | Friedrich-Schiller-Universität Jena | Kohlenmonoxid und Eisen freisetzende Moleküle, deren Verwendung und Verfahren zu deren Herstellung |
RS59080B1 (sr) | 2011-03-31 | 2019-09-30 | Adc Therapeutics Sa | Antitela protiv antigena 1 povezanog sa bubrezima i njihovi fragmenti koji se vezuju za antigen |
EP2699242B1 (en) | 2011-04-19 | 2017-11-01 | Alfama, Inc. | Carbon monoxide releasing molecules and uses thereof |
WO2013013179A1 (en) | 2011-07-21 | 2013-01-24 | Alfama, Inc. | Ruthenium carbon monoxide releasing molecules and uses thereof |
PL2802351T3 (pl) | 2012-01-09 | 2019-11-29 | Adc Therapeutics Sa | Środki do leczenia potrójnie negatywnego raka piersi |
DE102012004132A1 (de) | 2012-02-29 | 2013-08-29 | Friedrich-Schiller-Universität Jena | Kohlenstoffmonoxid freisetzende Materialien und deren Verwendung |
DE102014008537A1 (de) | 2014-06-04 | 2015-12-17 | Friedrich-Schiller-Universität Jena | Wasserlösliche manganbasierte Kohlenstoffmonoxid freisetzende Moleküle, deren Verwendung und Verfahren zu deren Herstellung |
EP3212610B1 (en) * | 2014-10-30 | 2020-10-28 | Katholieke Universiteit Leuven | Methods for low temperature fluorine-18 radiolabeling of biomolecules |
CN113429456B (zh) * | 2021-06-11 | 2022-05-31 | 首都医科大学 | 多肽衍生物钌类络合物及其制备方法和应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4721669A (en) * | 1985-01-18 | 1988-01-26 | The Trustees Of Columbia University In The City Of New York | Chemical probes for left-handed DNA and chiral metal complexes as Z-specific anti-tumor agents |
US5112974A (en) * | 1985-01-18 | 1992-05-12 | The Trustees Of Columbia University In The City Of New York | Mixed ligand complexes and uses thereof as binding agents to DNA |
GB9317686D0 (en) * | 1993-08-25 | 1993-10-13 | Johnson Matthey Plc | Pharmaceutical compositions |
SE9703396D0 (sv) * | 1997-09-19 | 1997-09-19 | Lincoln | Binuclear complex |
-
2000
- 2000-03-17 AU AU32685/00A patent/AU3268500A/en not_active Abandoned
- 2000-03-17 JP JP2000606604A patent/JP2004500321A/ja not_active Withdrawn
- 2000-03-17 CN CN00806748A patent/CN1391577A/zh active Pending
- 2000-03-17 BR BR0011678-5A patent/BR0011678A/pt not_active Application Discontinuation
- 2000-03-17 EP EP00910468A patent/EP1163247A1/en not_active Withdrawn
- 2000-03-17 HU HU0400457A patent/HUP0400457A2/hu unknown
- 2000-03-17 CZ CZ20013307A patent/CZ20013307A3/cs unknown
- 2000-03-17 IL IL14529000A patent/IL145290A0/xx unknown
- 2000-03-17 KR KR1020017011819A patent/KR20010112343A/ko not_active Application Discontinuation
- 2000-03-17 US US09/527,450 patent/US20020049190A1/en not_active Abandoned
- 2000-03-17 WO PCT/CA2000/000294 patent/WO2000056743A1/en not_active Application Discontinuation
- 2000-03-17 CA CA002367282A patent/CA2367282A1/en not_active Abandoned
- 2000-03-17 MX MXPA01009410A patent/MXPA01009410A/es unknown
- 2000-03-17 PL PL00356683A patent/PL356683A1/xx not_active Application Discontinuation
-
2001
- 2001-09-18 NO NO20014526A patent/NO20014526L/no unknown
Also Published As
Publication number | Publication date |
---|---|
AU3268500A (en) | 2000-10-09 |
KR20010112343A (ko) | 2001-12-20 |
CZ20013307A3 (cs) | 2002-05-15 |
US20020049190A1 (en) | 2002-04-25 |
CN1391577A (zh) | 2003-01-15 |
JP2004500321A (ja) | 2004-01-08 |
NO20014526L (no) | 2001-10-16 |
CA2367282A1 (en) | 2000-09-28 |
WO2000056743A1 (en) | 2000-09-28 |
PL356683A1 (en) | 2004-06-28 |
IL145290A0 (en) | 2002-06-30 |
EP1163247A1 (en) | 2001-12-19 |
NO20014526D0 (no) | 2001-09-18 |
MXPA01009410A (es) | 2003-06-06 |
HUP0400457A2 (hu) | 2004-05-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR0011678A (pt) | Composições farmacêuticas compreendendo complexos de metal | |
HK1040721A1 (en) | Glycopeptide derivatives and pharmaceutical compositions containing the same | |
KR900002784A (ko) | 항종양치료에 사용하기 위한 약제학적 결합제제 | |
BR9303993A (pt) | Composto, processo para preparar o mesmo e composição farmacêutica | |
HUP0102422A3 (en) | Isothiazole derivatives useful as anticancer agents, pharmaceutical compositions containing such compounds and processes for their preparation | |
IL103301A0 (en) | Pyrimidine nucleoside derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same | |
BR9813390A (pt) | Composto, processo para a preparação do mesmo, e uso do mesmo, composição farmacêutica, processo para a preparação da mesma, e, processo para efetuar a imunossupressão | |
TW272195B (pt) | ||
IL73632A (en) | N-acylated substituted trans-1,2-diaminocyclohexane compounds,their preparation and pharmaceutical compositions containing them | |
IL73660A (en) | N-acylated substituted trans-1,2-diaminocyclohexane compounds,their preparation and pharmaceutical compositions containing them | |
BR0214038A (pt) | Composições catalisadoras de imino-amida para a polimerização de olefinas | |
NO984470L (no) | Pyrrolopyrrolon-derivater som inhibitorer for neutrofil elastase | |
TW349094B (en) | Compositions and methods for controlling harmful fungi | |
CA2186731A1 (en) | Trinuclear cationic platinum complexes having antitumour activity and pharmaceutical compositions containing them | |
DK0714387T3 (da) | Hidtil ukendte bis-naphthalimider til behandling af cancer | |
KR890014107A (ko) | 백금 화학 요법약제 | |
CA2188798A1 (en) | Tryptamine Derivatives as 5-HT-1D Receptor Ligands | |
MA24721A1 (fr) | Compositions nouvelles renfermant des derives de benzopyranne et pyrydopyranne et procede pour leur preparation | |
ATE326450T1 (de) | Metallkomplexe und deren therapeutische verwendungen | |
DK0972521T3 (da) | Farmaceutisk præparat, der indeholder interferon-gamma-stimulatorer | |
ATE373955T1 (de) | Bakterizide zusammensetzungen und diese enthaltende artikel | |
BR9608473A (pt) | Complexo organometálico do ferro, composição para o tratamento do paludismo, e, utilização de um composto | |
BR0213955A (pt) | Processo para a telomerização de um dieno conjugado, ligando bidentado, sistema catalìtico, e, processo para a preparação de 1-octeno | |
PT1107750E (pt) | Composicao farmaceutica, a base de carboplatina, com actividade anti-tumor | |
ATE236179T1 (de) | Nitrate von bis-platinum komplexen mit polyamin |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA10 | Dismissal: dismissal - article 33 of industrial property law | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |