BR0011678A - Composições farmacêuticas compreendendo complexos de metal - Google Patents

Composições farmacêuticas compreendendo complexos de metal

Info

Publication number
BR0011678A
BR0011678A BR0011678-5A BR0011678A BR0011678A BR 0011678 A BR0011678 A BR 0011678A BR 0011678 A BR0011678 A BR 0011678A BR 0011678 A BR0011678 A BR 0011678A
Authority
BR
Brazil
Prior art keywords
group
mixture
pharmaceutical compositions
metal complexes
ions
Prior art date
Application number
BR0011678-5A
Other languages
English (en)
Inventor
Simon Fricker
Michael J Abrams
Gary Bridger
Renato Skerlj
Ian Baird
Beth R Cameron
Original Assignee
Anormed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anormed Inc filed Critical Anormed Inc
Publication of BR0011678A publication Critical patent/BR0011678A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F19/00—Metal compounds according to more than one of main groups C07F1/00 - C07F17/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0046—Ruthenium compounds
    • C07F15/0053—Ruthenium compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/295—Iron group metal compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Patente de Invenção: "COMPOSIçõES FARMACêUTICAS COMPREENDENDO COMPLEXOS DE METAL". Um composto de fórmula [M~ a~(X~ b~L)~ c~Y~ d~Z~ e~]^ nt<sym>^ em que: M é um íon de metal ou uma mistura de íons de metal; X é um cátion ou uma mistura de cátions; L é um ligando ou mistura de ligandos, cada um contendo pelo menos dois átomos doadores diferentes selecionados dos elementos do Grupo IV, Grupo V ou Grupo VI da Tabela Periódica; Y é um ligando ou uma mistura dos mesmos ou de ligandos diferentes, cada um contendo pelo menos um átomo doador ou mais do que um átomo doador, selecionado dos elementos do Grupo IV, Grupo V ou Grupo VI da Tabela Periódica; e Z é um íon de haleto ou pseudo-haleto ou uma mistura de íons de haleto e íons de pseudo-haleto; e em que: a = 1-3; b = 0-12; c = 0-18; d = 0-18; e = 0-18; e n = 0-10; contanto que pelo menos um de c, d e e seja 1 ou mais; em que c é 0: b também é 0; em que a é 1: c, d e e não são maiores do que 9; e em que a é 2: c, d e e não são maiores do que 12.
BR0011678-5A 1999-03-19 2000-03-17 Composições farmacêuticas compreendendo complexos de metal BR0011678A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12516699P 1999-03-19 1999-03-19
PCT/CA2000/000294 WO2000056743A1 (en) 1999-03-19 2000-03-17 Pharmaceutical compositions comprising metal complexes

Publications (1)

Publication Number Publication Date
BR0011678A true BR0011678A (pt) 2002-02-26

Family

ID=22418482

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0011678-5A BR0011678A (pt) 1999-03-19 2000-03-17 Composições farmacêuticas compreendendo complexos de metal

Country Status (15)

Country Link
US (1) US20020049190A1 (pt)
EP (1) EP1163247A1 (pt)
JP (1) JP2004500321A (pt)
KR (1) KR20010112343A (pt)
CN (1) CN1391577A (pt)
AU (1) AU3268500A (pt)
BR (1) BR0011678A (pt)
CA (1) CA2367282A1 (pt)
CZ (1) CZ20013307A3 (pt)
HU (1) HUP0400457A2 (pt)
IL (1) IL145290A0 (pt)
MX (1) MXPA01009410A (pt)
NO (1) NO20014526L (pt)
PL (1) PL356683A1 (pt)
WO (1) WO2000056743A1 (pt)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ303156B6 (cs) 1999-04-13 2012-05-09 Anormed Inc. Komplex cisplatiny a zpusob jeho prípravy
JP4227701B2 (ja) * 1999-05-25 2009-02-18 中部キレスト株式会社 ジエチレントリアミン五酢酸ルテニウム二アンモニウム塩またはその水和物およびその製法
US6489638B2 (en) * 2000-06-23 2002-12-03 Semiconductor Energy Laboratory Co., Ltd. Light emitting device
US6894049B1 (en) 2000-10-04 2005-05-17 Anormed, Inc. Platinum complexes as antitumor agents
US20020072512A1 (en) * 2000-12-08 2002-06-13 Metaphore Pharmaceuticals, Inc Method of preventing and treating HIV-mediated central nervous system damage
GB0111872D0 (en) 2001-05-15 2001-07-04 Northwick Park Inst For Medica Therapeutic agents and methods
US7011854B2 (en) 2002-02-04 2006-03-14 Alfama-Investigacao e Desenvolvimento de Produtos Farmaceuticos Lda Method for treating a mammal by administration of a compound having the ability to release CO, compounds having the ability to release CO and pharmaceutical compositions thereof
GB2395432B (en) * 2002-11-20 2005-09-14 Northwick Park Inst For Medica Therapeutic delivery of carbon monoxide to extracorporeal and isolated organs
GB2395431A (en) * 2002-11-20 2004-05-26 Northwick Park Inst For Medica Combination of a metal carbonyl compound and a guanylate cyclase stimulant or stabilizer for the therapeutic delivery of carbon monoxide
ES2390457T3 (es) * 2003-08-04 2012-11-13 Johnson & Johnson Consumer Companies, Inc. Métodos para el tratamiento de enfermedades dermatológicas
NZ548440A (en) 2004-02-05 2009-07-31 Kyorin Seiyaku Kk Bicycloester derivative inhibitng DPP-IV for treatment of diabetes or similar
FR2873037B1 (fr) * 2004-07-13 2008-04-11 Univ Pasteur Methodes et compositions pour le traitement de cancers
MX2008008104A (es) * 2005-12-21 2008-09-03 Oxford Biosensors Ltd Mediadores redox.
GB0601394D0 (en) 2006-01-24 2006-03-01 Hemocorm Ltd Therapeutic delivery of carbon monoxide
CN101395131B (zh) 2006-03-08 2012-11-14 杏林制药株式会社 氨基乙酰基吡咯烷甲腈衍生物的制备方法及其制备中间体
CA2655933C (en) 2006-06-23 2014-09-09 Alethia Biotherapeutics Inc. Polynucleotides and polypeptide sequences involved in cancer
WO2008038305A2 (en) * 2006-09-26 2008-04-03 Jegannathan Srinivas Therapeutical formulation comprising a thiazolidinedione and a nitric oxide scavenger.
WO2008114857A1 (ja) 2007-03-22 2008-09-25 Kyorin Pharmaceutical Co., Ltd. アミノアセチルピロリジンカルボニトリル誘導体の製造方法
CA3050455A1 (en) 2008-11-03 2010-06-03 Adc Therapeutics Sa Antibodies that specifically block the biological activity of a tumor antigen
DE102010014412A1 (de) 2010-04-08 2012-04-19 Friedrich-Schiller-Universität Jena Verwendung von zweikernigen Eisenkomplexen mit schwefelhaltigen Liganden als pharmakologische Wirkstoffe
DE102010014411A1 (de) 2010-04-08 2011-10-13 Friedrich-Schiller-Universität Jena Kohlenmonoxid und Eisen freisetzende Moleküle, deren Verwendung und Verfahren zu deren Herstellung
RS59080B1 (sr) 2011-03-31 2019-09-30 Adc Therapeutics Sa Antitela protiv antigena 1 povezanog sa bubrezima i njihovi fragmenti koji se vezuju za antigen
EP2699242B1 (en) 2011-04-19 2017-11-01 Alfama, Inc. Carbon monoxide releasing molecules and uses thereof
WO2013013179A1 (en) 2011-07-21 2013-01-24 Alfama, Inc. Ruthenium carbon monoxide releasing molecules and uses thereof
PL2802351T3 (pl) 2012-01-09 2019-11-29 Adc Therapeutics Sa Środki do leczenia potrójnie negatywnego raka piersi
DE102012004132A1 (de) 2012-02-29 2013-08-29 Friedrich-Schiller-Universität Jena Kohlenstoffmonoxid freisetzende Materialien und deren Verwendung
DE102014008537A1 (de) 2014-06-04 2015-12-17 Friedrich-Schiller-Universität Jena Wasserlösliche manganbasierte Kohlenstoffmonoxid freisetzende Moleküle, deren Verwendung und Verfahren zu deren Herstellung
EP3212610B1 (en) * 2014-10-30 2020-10-28 Katholieke Universiteit Leuven Methods for low temperature fluorine-18 radiolabeling of biomolecules
CN113429456B (zh) * 2021-06-11 2022-05-31 首都医科大学 多肽衍生物钌类络合物及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4721669A (en) * 1985-01-18 1988-01-26 The Trustees Of Columbia University In The City Of New York Chemical probes for left-handed DNA and chiral metal complexes as Z-specific anti-tumor agents
US5112974A (en) * 1985-01-18 1992-05-12 The Trustees Of Columbia University In The City Of New York Mixed ligand complexes and uses thereof as binding agents to DNA
GB9317686D0 (en) * 1993-08-25 1993-10-13 Johnson Matthey Plc Pharmaceutical compositions
SE9703396D0 (sv) * 1997-09-19 1997-09-19 Lincoln Binuclear complex

Also Published As

Publication number Publication date
AU3268500A (en) 2000-10-09
KR20010112343A (ko) 2001-12-20
CZ20013307A3 (cs) 2002-05-15
US20020049190A1 (en) 2002-04-25
CN1391577A (zh) 2003-01-15
JP2004500321A (ja) 2004-01-08
NO20014526L (no) 2001-10-16
CA2367282A1 (en) 2000-09-28
WO2000056743A1 (en) 2000-09-28
PL356683A1 (en) 2004-06-28
IL145290A0 (en) 2002-06-30
EP1163247A1 (en) 2001-12-19
NO20014526D0 (no) 2001-09-18
MXPA01009410A (es) 2003-06-06
HUP0400457A2 (hu) 2004-05-28

Similar Documents

Publication Publication Date Title
BR0011678A (pt) Composições farmacêuticas compreendendo complexos de metal
HK1040721A1 (en) Glycopeptide derivatives and pharmaceutical compositions containing the same
KR900002784A (ko) 항종양치료에 사용하기 위한 약제학적 결합제제
BR9303993A (pt) Composto, processo para preparar o mesmo e composição farmacêutica
HUP0102422A3 (en) Isothiazole derivatives useful as anticancer agents, pharmaceutical compositions containing such compounds and processes for their preparation
IL103301A0 (en) Pyrimidine nucleoside derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
BR9813390A (pt) Composto, processo para a preparação do mesmo, e uso do mesmo, composição farmacêutica, processo para a preparação da mesma, e, processo para efetuar a imunossupressão
TW272195B (pt)
IL73632A (en) N-acylated substituted trans-1,2-diaminocyclohexane compounds,their preparation and pharmaceutical compositions containing them
IL73660A (en) N-acylated substituted trans-1,2-diaminocyclohexane compounds,their preparation and pharmaceutical compositions containing them
BR0214038A (pt) Composições catalisadoras de imino-amida para a polimerização de olefinas
NO984470L (no) Pyrrolopyrrolon-derivater som inhibitorer for neutrofil elastase
TW349094B (en) Compositions and methods for controlling harmful fungi
CA2186731A1 (en) Trinuclear cationic platinum complexes having antitumour activity and pharmaceutical compositions containing them
DK0714387T3 (da) Hidtil ukendte bis-naphthalimider til behandling af cancer
KR890014107A (ko) 백금 화학 요법약제
CA2188798A1 (en) Tryptamine Derivatives as 5-HT-1D Receptor Ligands
MA24721A1 (fr) Compositions nouvelles renfermant des derives de benzopyranne et pyrydopyranne et procede pour leur preparation
ATE326450T1 (de) Metallkomplexe und deren therapeutische verwendungen
DK0972521T3 (da) Farmaceutisk præparat, der indeholder interferon-gamma-stimulatorer
ATE373955T1 (de) Bakterizide zusammensetzungen und diese enthaltende artikel
BR9608473A (pt) Complexo organometálico do ferro, composição para o tratamento do paludismo, e, utilização de um composto
BR0213955A (pt) Processo para a telomerização de um dieno conjugado, ligando bidentado, sistema catalìtico, e, processo para a preparação de 1-octeno
PT1107750E (pt) Composicao farmaceutica, a base de carboplatina, com actividade anti-tumor
ATE236179T1 (de) Nitrate von bis-platinum komplexen mit polyamin

Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]