BR0010199A - Processo para preparação de l-fosfinotricina por transaminação enzimática com aspartato - Google Patents

Processo para preparação de l-fosfinotricina por transaminação enzimática com aspartato

Info

Publication number
BR0010199A
BR0010199A BR0010199-0A BR0010199A BR0010199A BR 0010199 A BR0010199 A BR 0010199A BR 0010199 A BR0010199 A BR 0010199A BR 0010199 A BR0010199 A BR 0010199A
Authority
BR
Brazil
Prior art keywords
aspartate
enzymatic
transamination
phosphinothricin
preparation
Prior art date
Application number
BR0010199-0A
Other languages
English (en)
Inventor
Klaus Bartsch
Original Assignee
Aventis Cropscience Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Cropscience Gmbh filed Critical Aventis Cropscience Gmbh
Publication of BR0010199A publication Critical patent/BR0010199A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Patente de Invenção: "PROCESSO PARA PREPARAçãO DE L-FOSFINO-TRICINA POR TRANSAMINAçãO ENZIMáTICA COM ASPARTATO". O pedido de patente descreve um processo para síntese quiral, enzimática de L-fosfinotricina por transaminação a partir de seu cetoácido PPO correspondente com aspartato como aminodoador. Através da condução apropriada da reação pode ser obtida uma conversão quantitativa com o emprego de quantidades aproximadamente equimolares de aminodoador e aminoaceptor sob total consumo dos aminoácidos doadores Aspartato. O emprego de transaminases termoestáveis possibilita uma elevada velocidade de reação e respectivos rendimentos espaço-tempo.
BR0010199-0A 1999-04-30 2000-03-30 Processo para preparação de l-fosfinotricina por transaminação enzimática com aspartato BR0010199A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19919848A DE19919848A1 (de) 1999-04-30 1999-04-30 Verfahren zur Herstellung von L-Phosphinothricin durch enzymatische Transaminierung mit Aspartat
PCT/EP2000/002809 WO2000066760A1 (de) 1999-04-30 2000-03-30 Verfahren zur herstellung von l-phosphinothricin durch enzymatische transaminierung mit aspartat

Publications (1)

Publication Number Publication Date
BR0010199A true BR0010199A (pt) 2002-01-08

Family

ID=7906505

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0010199-0A BR0010199A (pt) 1999-04-30 2000-03-30 Processo para preparação de l-fosfinotricina por transaminação enzimática com aspartato

Country Status (22)

Country Link
US (1) US6936444B1 (pt)
EP (1) EP1177310B1 (pt)
JP (1) JP2003528572A (pt)
KR (1) KR100810169B1 (pt)
CN (1) CN1284858C (pt)
AT (1) ATE287965T1 (pt)
AU (1) AU768315B2 (pt)
BR (1) BR0010199A (pt)
CA (1) CA2370109C (pt)
CZ (1) CZ20013901A3 (pt)
DE (2) DE19919848A1 (pt)
DK (1) DK1177310T3 (pt)
ES (1) ES2235865T3 (pt)
HU (1) HU228395B1 (pt)
IL (2) IL145925A0 (pt)
MX (1) MXPA01011016A (pt)
NZ (1) NZ515088A (pt)
PL (1) PL202575B1 (pt)
RU (1) RU2275428C2 (pt)
SK (1) SK286456B6 (pt)
UA (1) UA75331C2 (pt)
WO (1) WO2000066760A1 (pt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1864989B1 (en) 2005-03-29 2012-07-18 Meiji Seika Pharma Co., Ltd. Method for producing l-2-amino-4-(hydroxymethylphosphinyl)- butanoic acid
EP1818411A1 (en) * 2006-02-13 2007-08-15 Lonza AG Process for the preparation of optically active chiral amines
CN101395271B (zh) * 2006-03-02 2013-02-27 明治制果株式会社 天冬氨酸转氨酶基因和l-膦丝菌素的制备方法
TWI412533B (zh) 2006-09-04 2013-10-21 Meiji Seika Pharma Co Ltd 光學活性胺基氧膦基丁酸類之製造方法
TWI397380B (zh) 2006-09-20 2013-06-01 Meiji Seika Kaisha 含磷之α胺基酸之製造方法及其製造中間體
US8017797B2 (en) 2007-03-23 2011-09-13 Meiji Seika Kaisha Ltd. Method for producing phosphorus-containing α-keto acid
DK3354727T3 (da) 2009-01-08 2020-11-16 Codexis Inc Transaminasepolypeptider
EP2401366B1 (en) 2009-02-26 2013-12-18 Codexis, Inc. Transaminase biocatalysts
WO2011005477A1 (en) 2009-06-22 2011-01-13 Codexis, Inc. Transaminase reactions
CA2796158C (en) 2010-04-14 2022-06-14 Strategic Enzyme Applications, Inc. Process for producing phosphinothricin employing nitrilases
US8852900B2 (en) 2010-06-17 2014-10-07 Codexis, Inc. Biocatalysts and methods for the synthesis of (S)-3-(1-aminoethyl)-phenol
WO2012024104A2 (en) 2010-08-16 2012-02-23 Codexis, Inc. Biocatalysts and methods for the synthesis of (1r,2r)-2-(3,4-dimethoxyphenethoxy)cyclohexanamine
CN105603015B (zh) * 2016-01-22 2018-12-11 浙江大学 一种l-草铵膦的生产方法
EP3423585A1 (en) 2016-03-02 2019-01-09 Agrimetis, LLC Methods for making l-glufosinate
CN106916857B (zh) * 2017-03-09 2019-08-27 浙江大学 一种生产l-草铵膦的方法
CN107119084B (zh) * 2017-03-23 2019-12-17 浙江大学 一种利用转氨酶和乙烯合成酶生产l-草铵膦的方法
CN110343676B (zh) 2018-04-03 2020-06-23 上海弈柯莱生物医药科技有限公司 一种l-谷氨酸脱氢酶突变体及其应用
US20210214754A1 (en) 2018-09-05 2021-07-15 Basf Se Methods for improving yields of l-glufosinate
CN109369711A (zh) * 2018-10-26 2019-02-22 洪湖市泰科技有限公司 一种l-草胺膦关键中间体的合成新方法
CN111019916B (zh) 2018-11-23 2020-12-08 弈柯莱生物科技(上海)股份有限公司 一种d-氨基酸氧化酶突变体及其应用
CN111979208B (zh) 2019-05-23 2023-01-10 弈柯莱生物科技(上海)股份有限公司 一种l-谷氨酸脱氢酶突变体及其应用
CN112725298B (zh) 2020-12-31 2022-12-06 浙江工业大学 一种机器学习基因挖掘方法及氨基转位用草铵膦脱氢酶突变体

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2717440C2 (de) 1976-05-17 1984-04-05 Hoechst Ag, 6230 Frankfurt Unkrautbekämpfung mit [(3-Amino-3-carboxy)-propyl-1]-methylphosphinsäure-Derivaten
US4265654A (en) 1977-12-28 1981-05-05 Meiji Seika Kaisha Ltd. Herbicidal compositions
HU193902B (en) * 1983-09-01 1987-12-28 Genetics Inst Process for preparing l-amino acids by means of transamination
US4826766A (en) 1985-09-23 1989-05-02 Genetics Institute, Inc. Production of amino acids using coupled aminotransferases
DE3786707D1 (de) * 1986-06-04 1993-09-02 Hoechst Ag Verfahren zur herstellung von l-phosphinothricin durch transaminierung.
AU599985B2 (en) * 1986-06-09 1990-08-02 Meiji Seika Kaisha Ltd. New process for the production of L-2-amino-4- (hydroxymethyl-phosphinyl)-butyric acid
DE3818851A1 (de) 1988-06-03 1989-12-14 Hoechst Ag Neue transaminase, ihre herstellung und ihre verwendung
EP0349965A3 (en) * 1988-07-04 1990-06-13 Meiji Seika Kaisha Ltd. Novel genes encoding transaminase
DE3932015A1 (de) 1988-12-15 1991-04-04 Hoechst Ag Gen und genstruktur, codierend fuer eine aminotransferase, mikroorganismen, die dieses gen exprimieren, und transaminierungsverfahren unter verwendung des expressionsprodukts
DE4030578A1 (de) * 1990-09-27 1992-04-16 Hoechst Ag Verfahren zur herstellung von l-phosphinothricin durch eine gekoppelte enzymatische reaktion
US5962283A (en) 1995-12-07 1999-10-05 Diversa Corporation Transminases and amnotransferases
US6197558B1 (en) * 1997-05-19 2001-03-06 Nsc Technologies Transaminase biotransformation process

Also Published As

Publication number Publication date
ATE287965T1 (de) 2005-02-15
KR100810169B1 (ko) 2008-03-06
HU228395B1 (en) 2013-03-28
IL145925A (en) 2007-05-15
HUP0200948A3 (en) 2010-01-28
SK15622001A3 (sk) 2002-06-04
CZ20013901A3 (cs) 2002-02-13
HUP0200948A2 (hu) 2002-07-29
CN1349561A (zh) 2002-05-15
DE19919848A1 (de) 2000-11-02
ES2235865T3 (es) 2005-07-16
EP1177310B1 (de) 2005-01-26
CN1284858C (zh) 2006-11-15
MXPA01011016A (es) 2002-05-06
US6936444B1 (en) 2005-08-30
JP2003528572A (ja) 2003-09-30
EP1177310A1 (de) 2002-02-06
AU768315B2 (en) 2003-12-11
PL202575B1 (pl) 2009-07-31
UA75331C2 (en) 2006-04-17
PL353460A1 (en) 2003-11-17
RU2275428C2 (ru) 2006-04-27
CA2370109C (en) 2009-07-07
WO2000066760A1 (de) 2000-11-09
AU4540800A (en) 2000-11-17
IL145925A0 (en) 2002-07-25
SK286456B6 (sk) 2008-10-07
KR20010112473A (ko) 2001-12-20
DK1177310T3 (da) 2005-04-11
CA2370109A1 (en) 2000-11-09
NZ515088A (en) 2003-06-30
DE50009364D1 (de) 2005-03-03

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B25D Requested change of name of applicant approved

Owner name: BAYER CROPSCIENCE GMBH (DE)

Free format text: ALTERADO DE: AVENTIS CROPSCIENCE GMBH

B25A Requested transfer of rights approved

Owner name: BAYER CROPSCIENCE AG (DE)

Free format text: TRANSFERIDO DE: BAYER CROPSCIENCE GMBH

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 10 (IX) E 25 DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.