BG99839A - Хетероароматни съединения с антипсихотичен ефект - Google Patents

Хетероароматни съединения с антипсихотичен ефект Download PDF

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Publication number
BG99839A
BG99839A BG99839A BG9983995A BG99839A BG 99839 A BG99839 A BG 99839A BG 99839 A BG99839 A BG 99839A BG 9983995 A BG9983995 A BG 9983995A BG 99839 A BG99839 A BG 99839A
Authority
BG
Bulgaria
Prior art keywords
butyl
benzisothiazol
piperazinyl
formula
compound
Prior art date
Application number
BG99839A
Other languages
Bulgarian (bg)
English (en)
Inventor
Mark Norman
Frank Navas
Original Assignee
Mark Norman
Frank Navas
The Wellcome Foundation Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mark Norman, Frank Navas, The Wellcome Foundation Limited filed Critical Mark Norman
Publication of BG99839A publication Critical patent/BG99839A/bg

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
BG99839A 1993-02-10 1995-08-02 Хетероароматни съединения с антипсихотичен ефект BG99839A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939302622A GB9302622D0 (en) 1993-02-10 1993-02-10 Heteroaromatic compounds
PCT/GB1994/000265 WO1994018196A1 (en) 1993-02-10 1994-02-10 Heteroaromatic compounds with antipsychotic activity

Publications (1)

Publication Number Publication Date
BG99839A true BG99839A (bg) 1996-02-28

Family

ID=10730183

Family Applications (1)

Application Number Title Priority Date Filing Date
BG99839A BG99839A (bg) 1993-02-10 1995-08-02 Хетероароматни съединения с антипсихотичен ефект

Country Status (15)

Country Link
EP (1) EP0683778A1 (ja)
JP (1) JPH08506337A (ja)
CN (1) CN1117731A (ja)
AU (1) AU6005194A (ja)
BG (1) BG99839A (ja)
CA (1) CA2155758A1 (ja)
CZ (1) CZ204495A3 (ja)
FI (1) FI953777A (ja)
GB (1) GB9302622D0 (ja)
HU (1) HUT73654A (ja)
IL (1) IL108601A0 (ja)
MX (1) MX9401080A (ja)
SK (1) SK99195A3 (ja)
WO (1) WO1994018196A1 (ja)
ZA (1) ZA94891B (ja)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364866A (en) 1989-05-19 1994-11-15 Hoechst-Roussel Pharmaceuticals, Inc. Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics
US5776963A (en) * 1989-05-19 1998-07-07 Hoechst Marion Roussel, Inc. 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility
GB9420521D0 (en) * 1994-10-12 1994-11-30 Smithkline Beecham Plc Novel compounds
JP3274579B2 (ja) * 1995-01-12 2002-04-15 住友製薬株式会社 脳血管障害に伴う精神症候治療剤
EP0732332B1 (en) * 1995-03-17 2001-12-19 Aventis Pharmaceuticals Inc. Substituted benzothienylpiperazines, their use as medicaments, and processes for their preparation
UA73981C2 (en) 2000-03-10 2005-10-17 Merck Patent Gmbh (r)-(-)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane for treatment of extrapyramidal movement disorders (variants), pharmaceutical composition and kit
MXPA03004249A (es) * 2000-11-14 2003-09-22 Merck Patent Gmbh Nuevos usos de combinaciones selectivas antagonistas del receptor de dopamina d2 y agonistas del receptor de 5-ht1a.
JP4497815B2 (ja) * 2001-02-16 2010-07-07 アベンティス・ファーマスーティカルズ・インコーポレイテツド 新規な複素環式アミド誘導体およびドーパミンｄ３受容体リガンドとしてのその使用
CA2455621C (en) 2001-07-26 2010-11-16 Merck Patent Gesellschaft Mit Beschraenkter Haftung Use of (r/s)-(-/+) or (s)-(+)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]chromane for the treatment of extrapyramidal movement disorders
GB0222909D0 (en) 2002-10-03 2002-11-13 Astrazeneca Ab Novel process and intermediates
GB0222912D0 (en) 2002-10-03 2002-11-13 Astrazeneca Ab Novel process and intermediates
CN101018774A (zh) * 2004-07-20 2007-08-15 锡耶纳生物技术股份公司 α7烟碱性乙酰胆碱受体的调节剂和其治疗用途
CL2008000119A1 (es) 2007-01-16 2008-05-16 Wyeth Corp Compuestos derivados de pirazol, antagonistas del receptor nicotinico de acetilcolina; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como demencia senil, alzheimer y esquizofrenia.
US8981095B2 (en) 2011-07-28 2015-03-17 Mapi Pharma Ltd. Intermediate compounds and process for the preparation of lurasidone and salts thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0625181B2 (ja) * 1985-03-27 1994-04-06 住友製薬株式会社 新規なイミド誘導体
AU593194B2 (en) * 1986-09-26 1990-02-01 Sumitomo Pharmaceuticals Company, Limited Imide derivatives ,and their production and use
US5143923B1 (en) * 1991-04-29 1993-11-02 Hoechst-Roussel Pharmaceuticals Incorporated Benzoisothiazole-and benzisoxazole-3-carboxamides
MX9201991A (es) * 1991-05-02 1992-11-01 Jonh Wyeth & Brother Limited Derivados de piperazina y procedimiento para su preparacion.

Also Published As

Publication number Publication date
AU6005194A (en) 1994-08-29
EP0683778A1 (en) 1995-11-29
WO1994018196A1 (en) 1994-08-18
GB9302622D0 (en) 1993-03-24
HUT73654A (en) 1996-09-30
CA2155758A1 (en) 1994-08-18
CN1117731A (zh) 1996-02-28
IL108601A0 (en) 1994-05-30
FI953777A0 (fi) 1995-08-09
MX9401080A (es) 1994-08-31
CZ204495A3 (en) 1996-03-13
JPH08506337A (ja) 1996-07-09
ZA94891B (en) 1995-08-10
HU9501881D0 (en) 1995-08-28
FI953777A (fi) 1995-08-09
SK99195A3 (en) 1995-12-06

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