BG63276B1 - Метод за производство на модифициран инхибитор палидипин на колагениндуцирано тромбоцитно натрупване - Google Patents

Метод за производство на модифициран инхибитор палидипин на колагениндуцирано тромбоцитно натрупване Download PDF

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Publication number
BG63276B1
BG63276B1 BG101226A BG10122697A BG63276B1 BG 63276 B1 BG63276 B1 BG 63276B1 BG 101226 A BG101226 A BG 101226A BG 10122697 A BG10122697 A BG 10122697A BG 63276 B1 BG63276 B1 BG 63276B1
Authority
BG
Bulgaria
Prior art keywords
palidipine
asp
protein
seq
amino acid
Prior art date
Application number
BG101226A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG101226A (en
Inventor
Christiane Noeske-Jungblut
Andreas Becker
Bernard Haendler
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of BG101226A publication Critical patent/BG101226A/xx
Publication of BG63276B1 publication Critical patent/BG63276B1/bg

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
BG101226A 1994-09-12 1997-02-12 Метод за производство на модифициран инхибитор палидипин на колагениндуцирано тромбоцитно натрупване BG63276B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP94250224 1994-09-12
PCT/EP1995/003573 WO1996008563A1 (fr) 1994-09-12 1995-09-11 Procede de preparation d'un inhibiteur modifie de l'agregation plaquettaire induite par le collagene: la pallidipine

Publications (2)

Publication Number Publication Date
BG101226A BG101226A (en) 1998-10-30
BG63276B1 true BG63276B1 (bg) 2001-08-31

Family

ID=8217517

Family Applications (1)

Application Number Title Priority Date Filing Date
BG101226A BG63276B1 (bg) 1994-09-12 1997-02-12 Метод за производство на модифициран инхибитор палидипин на колагениндуцирано тромбоцитно натрупване

Country Status (22)

Country Link
US (1) US5882887A (fr)
EP (1) EP0781334A1 (fr)
JP (1) JPH10505502A (fr)
CN (1) CN1075836C (fr)
AU (1) AU701643B2 (fr)
BG (1) BG63276B1 (fr)
BR (1) BR9508910A (fr)
CA (1) CA2199719A1 (fr)
CZ (1) CZ76297A3 (fr)
FI (1) FI971013A (fr)
HU (1) HU222398B1 (fr)
IL (1) IL115272A0 (fr)
MX (1) MX9701720A (fr)
NO (1) NO971110L (fr)
NZ (1) NZ293261A (fr)
PL (1) PL184617B1 (fr)
RO (1) RO117971B1 (fr)
RU (1) RU2186110C2 (fr)
SI (1) SI9520093A (fr)
SK (1) SK29297A3 (fr)
WO (1) WO1996008563A1 (fr)
ZA (1) ZA957649B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1161530B1 (fr) * 1999-03-18 2005-05-18 MERCK PATENT GmbH Proteine permettant de bloquer l'adhesion des plaquettes
US20080254451A1 (en) * 2004-12-28 2008-10-16 Ares Trading S.A. Compositions and Methods for Treating Schizophrenia and Related Disorders
US20110034396A1 (en) * 2005-09-28 2011-02-10 Biovascular, Inc. Methods and compositions for inhibiting cell migration and treatment of inflammatory conditions
US7691839B2 (en) * 2005-09-28 2010-04-06 Biovascular, Inc. Methods and compositions for blocking platelet and cell adhesion, cell migration and inflammation
TWI391143B (zh) 2005-11-04 2013-04-01 Otsuka Pharma Co Ltd 血小板凝集抑制劑組成物
US9617302B2 (en) * 2011-06-14 2017-04-11 National Taiwan University Peptide compounds for inhibition of platelet aggregation
FR2979346B1 (fr) 2011-08-23 2013-09-27 Univ Joseph Fourier Nanocorps anti-vcam-1
WO2013119880A1 (fr) 2012-02-07 2013-08-15 Global Bio Therapeutics Usa, Inc. Procédé compartimenté d'administration d'acide nucléique et ses compositions et utilisations
DK2892920T3 (da) 2012-09-07 2020-06-08 Inst Nat Sante Rech Med Hæmmende peptider afledt af udløsningsreceptor udtrykt på myeloide celler-1 (trem-1) trem-lignende transskript 1 (tlt-1) og anvendelser deraf
US11364032B2 (en) 2013-08-08 2022-06-21 Global Bio Therapeutics, Inc. Clamp device for minimally invasive procedures and uses thereof
FR3058143B1 (fr) 2016-10-27 2021-03-12 Univ Grenoble Alpes Nanocorps anti-tau
CN118139655A (zh) 2021-08-13 2024-06-04 特里奥万斯控股公司 皮肤替代组合物及其产生和使用方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03503596A (ja) * 1987-06-24 1991-08-15 ノボ・ノルディスク　エー／エス 蛋白質若しくはポリペプチドの調製方法、該ポリペプチドをコードするｄｎａ配列、該ｄｎａ配列およびポリペプチドを有する微生物および該ポリペプチドの薬学的製剤としての利用
US5756454A (en) * 1991-09-05 1998-05-26 Schering Aktiengesellschaft Collagen-induced platelet aggregation inhibitor
RU2128705C1 (ru) * 1991-09-05 1999-04-10 Шеринг Аг Протеин, ингибирующий вызываемую коллагеном агрегацию тромбоцитов млекопитающих, рекомбинантный протеин, ингибирующий вызываемую коллагеном агрегацию тромбоцитов, фрагмент днк, кодирующий рекомбинантный протеин, вектор экспрессии (варианты), штамм культивируемых животных клеток внк - продуцент рекомбинантного протеина (варианты), способ получения рекомбинантного протеина, фармацевтическая композиция
US5705362A (en) * 1992-05-25 1998-01-06 Gist-Brocades, N.V. Modified signal sequences

Also Published As

Publication number Publication date
BG101226A (en) 1998-10-30
ZA957649B (en) 1996-04-15
WO1996008563A1 (fr) 1996-03-21
NO971110L (no) 1997-05-07
HUT76972A (hu) 1998-01-28
AU701643B2 (en) 1999-02-04
FI971013A0 (fi) 1997-03-11
NO971110D0 (no) 1997-03-11
IL115272A0 (en) 1995-12-31
JPH10505502A (ja) 1998-06-02
BR9508910A (pt) 1997-10-28
CA2199719A1 (fr) 1996-03-21
CN1159828A (zh) 1997-09-17
MX9701720A (es) 1997-06-28
EP0781334A1 (fr) 1997-07-02
AU3565795A (en) 1996-03-29
PL319078A1 (en) 1997-07-21
US5882887A (en) 1999-03-16
CZ76297A3 (cs) 1998-01-14
RO117971B1 (ro) 2002-11-29
HU222398B1 (hu) 2003-06-28
SK29297A3 (en) 1997-10-08
FI971013A (fi) 1997-03-11
SI9520093A (en) 1997-08-31
PL184617B1 (pl) 2002-11-29
CN1075836C (zh) 2001-12-05
NZ293261A (en) 1998-11-25
RU2186110C2 (ru) 2002-07-27

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