BG63159B1 - Производни на заместени 4-бифенил-4-хидрокси-маслени киселини като инхибитори на матрични металопротеази - Google Patents
Производни на заместени 4-бифенил-4-хидрокси-маслени киселини като инхибитори на матрични металопротеази Download PDFInfo
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- C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
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- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
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- C07C59/40—Unsaturated compounds
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- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
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- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
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- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
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- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Ophthalmology & Optometry (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Steroid Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3026496P | 1996-10-31 | 1996-10-31 | |
| PCT/US1997/019960 WO1998022436A1 (en) | 1996-10-31 | 1997-10-30 | Substituted 4-biphenyl-4-hydroxybutyric acid derivatives as matrix metalloprotease inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BG103426A BG103426A (en) | 2000-01-31 |
| BG63159B1 true BG63159B1 (bg) | 2001-05-31 |
Family
ID=21853363
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG103426A BG63159B1 (bg) | 1996-10-31 | 1999-05-21 | Производни на заместени 4-бифенил-4-хидрокси-маслени киселини като инхибитори на матрични металопротеази |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US5939583A (hu) |
| EP (1) | EP0937036B1 (hu) |
| JP (1) | JP2001505877A (hu) |
| KR (1) | KR20000052899A (hu) |
| CN (1) | CN1140508C (hu) |
| AR (1) | AR009137A1 (hu) |
| AT (1) | ATE210112T1 (hu) |
| AU (1) | AU731830B2 (hu) |
| BG (1) | BG63159B1 (hu) |
| BR (1) | BR9712707A (hu) |
| CA (1) | CA2268770A1 (hu) |
| CZ (1) | CZ148599A3 (hu) |
| DE (1) | DE69708909T2 (hu) |
| DK (1) | DK0937036T3 (hu) |
| EE (1) | EE03745B1 (hu) |
| ES (1) | ES2167021T3 (hu) |
| HU (1) | HUP9904664A3 (hu) |
| ID (1) | ID18712A (hu) |
| IL (1) | IL129420A (hu) |
| MY (1) | MY117687A (hu) |
| NO (1) | NO312629B1 (hu) |
| PL (1) | PL333112A1 (hu) |
| PT (1) | PT937036E (hu) |
| SK (1) | SK58399A3 (hu) |
| TR (1) | TR199900945T2 (hu) |
| TW (1) | TW464642B (hu) |
| UA (1) | UA57047C2 (hu) |
| WO (1) | WO1998022436A1 (hu) |
| ZA (1) | ZA979756B (hu) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2780402B1 (fr) * | 1998-06-30 | 2001-04-27 | Adir | Nouveaux composes acides carboxyliques et hydroxamiques inhibiteurs de metalloproteases, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| CA2356053A1 (en) * | 1998-12-30 | 2000-07-13 | Bayer Aktiengesellschaft | Use of substituted 4-biarylbutyric and 5-biarylpentanoic acid derivatives as matrix metalloprotease inhibitors for the treatment of respiratory diseases |
| EP1031349A1 (en) * | 1999-02-25 | 2000-08-30 | Bayer Aktiengesellschaft | Use of substituted 4-biarylbutyric and 5-biarylpentanoic acid derivatives for the treatment of cerebral diseases |
| DE10058163C2 (de) * | 2000-11-22 | 2003-07-10 | Bebig Isotopen Und Medizintech | Verfahren und Applikator zum Positionieren und/oder Auswerfen von Strahlenquellen über Hohlnadeln in biologisches Gewebe |
| EP2181704B1 (en) | 2002-12-30 | 2015-05-06 | Angiotech International Ag | Drug delivery from rapid gelling polymer composition |
| US8460243B2 (en) | 2003-06-10 | 2013-06-11 | Abbott Diabetes Care Inc. | Glucose measuring module and insulin pump combination |
| US7722536B2 (en) | 2003-07-15 | 2010-05-25 | Abbott Diabetes Care Inc. | Glucose measuring device integrated into a holster for a personal area network device |
| US20060010098A1 (en) | 2004-06-04 | 2006-01-12 | Goodnow Timothy T | Diabetes care host-client architecture and data management system |
| US8710261B2 (en) * | 2005-02-22 | 2014-04-29 | Ranbaxy Laboratories Limited | 5-phenyl-pentanoic acid derivatives as matrix metalloproteinase inhibitors for the treatment of asthma and other diseases |
| US7319152B2 (en) | 2005-09-19 | 2008-01-15 | Wyeth | 5-Aryl-indan-1-one and analogs useful as progesterone receptor modulators |
| US7414142B2 (en) | 2005-09-19 | 2008-08-19 | Wyeth | 5-aryl-indan-1-one oximes and analogs useful as progesterone receptor modulators |
| US20090118519A1 (en) * | 2006-04-17 | 2009-05-07 | Sumitomo Chemical Company, Limited | Production Method of Polycyclic Lactams |
| EP2474531A3 (en) * | 2006-08-22 | 2013-12-04 | Ranbaxy Laboratories Limited | Matrix metalloproteinase inhibitors |
| US10136845B2 (en) | 2011-02-28 | 2018-11-27 | Abbott Diabetes Care Inc. | Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same |
| JP6804352B2 (ja) * | 2017-03-22 | 2020-12-23 | 大阪瓦斯株式会社 | コラゲナーゼｍｍｐ１及び３の産生抑制剤 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1040735A (en) * | 1964-07-23 | 1966-09-01 | British Drug Houses Ltd | 4-aryl-3-hydroxybutyric acid and esters, amides and salts thereof |
| US4021479A (en) * | 1971-03-17 | 1977-05-03 | Boehringer Ingelheim Gmbh | Derivatives of 4-(4-biphenylyl)-butyric acid |
| ES446581A1 (es) * | 1975-04-04 | 1977-06-16 | Boots Co Ltd | Un procedimiento para preparar acidos 2-arilpropionicos. |
| US4151302A (en) * | 1975-06-28 | 1979-04-24 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Araliphatic dihalogen compounds composition and method of use |
| US4168385A (en) * | 1975-09-25 | 1979-09-18 | American Cyanamid Company | Hypolipemic phenylacetic acid derivatives |
| US4567289A (en) * | 1979-08-17 | 1986-01-28 | Merck & Co., Inc. | Substituted pyranone inhibitors of cholesterol synthesis |
| CA1223602A (en) * | 1983-05-25 | 1987-06-30 | Naohito Ohashi | Process for producing 3-(3,4-dihydroxyphenyl) serine |
| JPS60169462A (ja) * | 1984-02-15 | 1985-09-02 | Sumitomo Chem Co Ltd | 光学活性なフエニルセリン誘導体の製造法 |
| US4855321A (en) * | 1986-01-31 | 1989-08-08 | Merck & Co., Inc. | Antihypercholesterolemic compounds |
| US5001128A (en) * | 1987-12-21 | 1991-03-19 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | HMG-COA reductase inhibitors |
| US5393780A (en) * | 1993-03-26 | 1995-02-28 | Fujirebio Inc. | 4-fluorobiphenyl derivatives |
| US5789434A (en) * | 1994-11-15 | 1998-08-04 | Bayer Corporation | Derivatives of substituted 4-biarylbutyric acid as matrix metalloprotease inhibitors |
-
1997
- 1997-10-29 MY MYPI97005143A patent/MY117687A/en unknown
- 1997-10-30 CN CNB971809100A patent/CN1140508C/zh not_active Expired - Fee Related
- 1997-10-30 WO PCT/US1997/019960 patent/WO1998022436A1/en not_active Application Discontinuation
- 1997-10-30 CA CA002268770A patent/CA2268770A1/en not_active Abandoned
- 1997-10-30 US US08/960,921 patent/US5939583A/en not_active Expired - Fee Related
- 1997-10-30 BR BR9712707-8A patent/BR9712707A/pt unknown
- 1997-10-30 PT PT97945585T patent/PT937036E/pt unknown
- 1997-10-30 DK DK97945585T patent/DK0937036T3/da active
- 1997-10-30 SK SK583-99A patent/SK58399A3/sk unknown
- 1997-10-30 EP EP97945585A patent/EP0937036B1/en not_active Expired - Lifetime
- 1997-10-30 PL PL97333112A patent/PL333112A1/xx unknown
- 1997-10-30 UA UA99052950A patent/UA57047C2/uk unknown
- 1997-10-30 IL IL12942097A patent/IL129420A/xx not_active IP Right Cessation
- 1997-10-30 CZ CZ991485A patent/CZ148599A3/cs unknown
- 1997-10-30 TR TR1999/00945T patent/TR199900945T2/xx unknown
- 1997-10-30 HU HU9904664A patent/HUP9904664A3/hu unknown
- 1997-10-30 ES ES97945585T patent/ES2167021T3/es not_active Expired - Lifetime
- 1997-10-30 AR ARP970105054A patent/AR009137A1/es unknown
- 1997-10-30 TW TW086116305A patent/TW464642B/zh not_active IP Right Cessation
- 1997-10-30 ZA ZA9709756A patent/ZA979756B/xx unknown
- 1997-10-30 AT AT97945585T patent/ATE210112T1/de not_active IP Right Cessation
- 1997-10-30 KR KR1019990703763A patent/KR20000052899A/ko not_active Application Discontinuation
- 1997-10-30 DE DE69708909T patent/DE69708909T2/de not_active Expired - Fee Related
- 1997-10-30 AU AU51024/98A patent/AU731830B2/en not_active Ceased
- 1997-10-30 EE EEP199900180A patent/EE03745B1/xx not_active IP Right Cessation
- 1997-10-30 JP JP52367798A patent/JP2001505877A/ja active Pending
- 1997-10-31 ID IDP973569A patent/ID18712A/id unknown
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1999
- 1999-04-27 NO NO19991994A patent/NO312629B1/no not_active IP Right Cessation
- 1999-05-21 BG BG103426A patent/BG63159B1/bg unknown
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