BG62934B1 - НОВИ ПИРИМИДО(1,2-а)ИНДОЛИ - Google Patents

НОВИ ПИРИМИДО(1,2-а)ИНДОЛИ Download PDF

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Publication number
BG62934B1
BG62934B1 BG101379A BG10137997A BG62934B1 BG 62934 B1 BG62934 B1 BG 62934B1 BG 101379 A BG101379 A BG 101379A BG 10137997 A BG10137997 A BG 10137997A BG 62934 B1 BG62934 B1 BG 62934B1
Authority
BG
Bulgaria
Prior art keywords
carbon atoms
branched
branched chain
alkyl
optionally substituted
Prior art date
Application number
BG101379A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG101379A (en
Inventor
Ulrich Mueller
Peter Eckenberg
Rudi Gruetzmann
Hilmar Bischoff
Dirk Denzer
Stefan Wohlfeil
Stefan Lohmer
Ulrich Nielsch
Peter Kolkhof
Original Assignee
Bayer Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of BG101379A publication Critical patent/BG101379A/xx
Publication of BG62934B1 publication Critical patent/BG62934B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
BG101379A 1996-04-04 1997-04-02 НОВИ ПИРИМИДО(1,2-а)ИНДОЛИ BG62934B1 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19613550A DE19613550A1 (de) 1996-04-04 1996-04-04 Neue Pyrimido[1,2-a]indole

Publications (2)

Publication Number Publication Date
BG101379A BG101379A (en) 1997-11-28
BG62934B1 true BG62934B1 (bg) 2000-11-30

Family

ID=7790502

Family Applications (1)

Application Number Title Priority Date Filing Date
BG101379A BG62934B1 (bg) 1996-04-04 1997-04-02 НОВИ ПИРИМИДО(1,2-а)ИНДОЛИ

Country Status (33)

Country Link
US (1) US6114341A (sh)
EP (1) EP0799828A3 (sh)
JP (1) JPH1059972A (sh)
KR (1) KR970070008A (sh)
CN (2) CN1067393C (sh)
AR (1) AR006497A1 (sh)
AU (1) AU725786B2 (sh)
BG (1) BG62934B1 (sh)
BR (1) BR9701675A (sh)
CA (1) CA2201434A1 (sh)
CO (1) CO4520306A1 (sh)
CZ (1) CZ102297A3 (sh)
DE (1) DE19613550A1 (sh)
DZ (1) DZ2201A1 (sh)
EE (1) EE9700078A (sh)
HN (1) HN1997000045A (sh)
HR (1) HRP970154A2 (sh)
HU (1) HUP9700708A3 (sh)
ID (1) ID16520A (sh)
IL (3) IL131645A (sh)
MA (1) MA24131A1 (sh)
MY (1) MY126362A (sh)
NO (1) NO309092B1 (sh)
NZ (1) NZ314497A (sh)
PE (1) PE42398A1 (sh)
PL (1) PL319249A1 (sh)
SG (1) SG63698A1 (sh)
SK (1) SK42797A3 (sh)
SV (1) SV1997000025A (sh)
TN (1) TNSN97061A1 (sh)
TR (1) TR199700261A2 (sh)
YU (1) YU12397A (sh)
ZA (1) ZA972829B (sh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19826469A1 (de) * 1998-06-13 2000-05-25 Bayer Ag Verfahren zur Herstellung von 2,4-Dimethylcarbolin und 2,4-Dimethylpyrimido[1,2-a]indol
AU2001244635A1 (en) * 2000-03-30 2001-10-15 Yamanouchi Pharmaceutical Co..Ltd. Hydrazide derivatives
DE10030375A1 (de) * 2000-06-21 2002-01-03 Bayer Ag Verwendung von MTP-Inhibitoren zur Senkung von ppTRL
JP4254093B2 (ja) * 2001-10-17 2009-04-15 宇部興産株式会社 ５−ハロゲノインドールの製法
DE10349175A1 (de) * 2003-10-22 2005-05-19 Bayer Healthcare Ag Mittel zur Gewichtsreduktion
CA2558766A1 (en) 2004-03-05 2005-09-22 The Trustees Of The University Of Pennsylvania The use of mtp inhibitors for treating disorders or diseases associated with hyperlipidemia and hypercholesterolemia while minimizing side effects
US20080280922A1 (en) * 2004-04-09 2008-11-13 Marc Alois Celine Maria Engelen Intermittent Dosing Regimen For Overweight and Obese Subjects
US7967838B2 (en) 2005-05-12 2011-06-28 C. R. Bard, Inc. Removable embolus blood clot filter
CA2609783A1 (en) * 2005-05-27 2006-12-07 Pfizer Products Inc. Combination of a cannabinoid-1- receptor-antagonist and a microsomal triglyceride transfer protein inhibitor for treating obesity or mainataining weight loss
EP1912696A1 (en) 2005-08-09 2008-04-23 C.R.Bard, Inc. Embolus blood clot filter and delivery system
EP1948163A2 (en) * 2005-10-18 2008-07-30 Aegerion Pharmaceuticals Methods for treating disorders associated with hyperlipidemia in a mammal
US10188496B2 (en) 2006-05-02 2019-01-29 C. R. Bard, Inc. Vena cava filter formed from a sheet
US20080161279A1 (en) * 2006-12-21 2008-07-03 Wisler Gerald L Methods of Treating Obesity

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2200584A1 (de) * 1971-01-11 1972-07-27 Wyeth John & Brother Ltd Heterocyclische Verbindungen,Verfahren zu ihrer Herstellung und ihre Verwendung in pharmazeutischen Zubereitungen
ZA718536B (en) * 1971-01-11 1972-09-27 Wyeth John & Brother Ltd Heterocyclic compounds
GB8614246D0 (en) * 1986-06-11 1986-07-16 Wyeth John & Brother Ltd Substituted pyrimidoindoles
DE4112533A1 (de) * 1991-04-17 1992-10-22 Bayer Ag Verfahren zur herstellung von enantiomerenreinen substituierten (chinolin-2-yl-methoxy)phenyl-essigsaeuren
DE4200954A1 (de) * 1991-04-26 1992-10-29 Bayer Ag Heterocyclisch substituierte phenylessigsaeurederivate
US5576342A (en) * 1992-03-13 1996-11-19 Bayer Aktiengesellschaft Phenylglycinamides of heterocyclically substitued phenylacetic acid derivatives
DE4208052A1 (de) * 1992-03-13 1993-09-16 Bayer Ag Imidazolyl substituierte phenylessigsaeureamide
DE4208051A1 (de) * 1992-03-13 1993-09-16 Bayer Ag Substituierte phenylessigsaeureamide
DE4309968A1 (de) * 1993-03-26 1994-09-29 Bayer Ag Phenylglycinamide von heterocyclisch substituierten Phenylessigsäurederivaten
WO1994010174A1 (en) * 1992-11-05 1994-05-11 Smithkline Beecham Plc Piperidine derivatives as 5-ht4 receptor antagonists
DE4302956A1 (de) * 1993-02-03 1994-08-04 Bayer Ag Substituierte Imidazo(4,5-b)pyridine und Benzimidazole

Also Published As

Publication number Publication date
CZ102297A3 (en) 1997-10-15
SG63698A1 (en) 1999-03-30
MY126362A (en) 2006-09-29
CN1176965A (zh) 1998-03-25
NO971512D0 (no) 1997-04-03
HRP970154A2 (en) 1998-04-30
EP0799828A3 (de) 1998-04-08
IL131645A (en) 2000-12-06
JPH1059972A (ja) 1998-03-03
MX9702445A (es) 1997-10-31
EE9700078A (et) 1997-10-15
AU1660397A (en) 1997-10-09
US6114341A (en) 2000-09-05
YU12397A (sh) 1999-11-22
SV1997000025A (es) 1997-10-23
MA24131A1 (fr) 1997-10-01
BG101379A (en) 1997-11-28
NZ314497A (en) 1999-10-28
CN1312246A (zh) 2001-09-12
NO971512L (no) 1997-10-06
TR199700261A2 (xx) 1997-10-21
CN1067393C (zh) 2001-06-20
HUP9700708A2 (hu) 1998-10-28
AR006497A1 (es) 1999-08-25
ID16520A (id) 1997-10-09
HUP9700708A3 (en) 2000-01-28
NO309092B1 (no) 2000-12-11
CA2201434A1 (en) 1997-10-04
EP0799828A2 (de) 1997-10-08
BR9701675A (pt) 1998-11-03
ZA972829B (en) 1997-10-31
AU725786B2 (en) 2000-10-19
KR970070008A (ko) 1997-11-07
SK42797A3 (en) 1997-11-05
IL120590A (en) 2000-02-17
PL319249A1 (en) 1997-10-13
DE19613550A1 (de) 1997-10-09
TNSN97061A1 (fr) 2005-03-15
HU9700708D0 (en) 1997-05-28
HN1997000045A (es) 1997-06-26
IL131645A0 (en) 2001-01-28
CO4520306A1 (es) 1997-10-15
IL120590A0 (en) 1997-08-14
DZ2201A1 (fr) 2002-12-03
PE42398A1 (es) 1998-10-12

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