BG62142B1 - Нсv геномни последователности за диагностика и лечение - Google Patents

Нсv геномни последователности за диагностика и лечение Download PDF

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Publication number
BG62142B1
BG62142B1 BG98200A BG9820093A BG62142B1 BG 62142 B1 BG62142 B1 BG 62142B1 BG 98200 A BG98200 A BG 98200A BG 9820093 A BG9820093 A BG 9820093A BG 62142 B1 BG62142 B1 BG 62142B1
Authority
BG
Bulgaria
Prior art keywords
hcv
nucleic acid
sequence
acid sequence
sequences
Prior art date
Application number
BG98200A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG98200A (bg
Inventor
Tai-An Vha
Eileen Beall
Bruce Irvine
Janice Kolberg
Michael S. Urdea
Original Assignee
Chiron Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24800701&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BG62142(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiron Corporation filed Critical Chiron Corporation
Publication of BG98200A publication Critical patent/BG98200A/bg
Publication of BG62142B1 publication Critical patent/BG62142B1/bg

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/09Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/162Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/706Specific hybridization probes for hepatitis
    • C12Q1/707Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
BG98200A 1991-05-08 1993-11-05 Нсv геномни последователности за диагностика и лечение BG62142B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69732691A 1991-05-08 1991-05-08
PCT/US1992/004036 WO1992019743A2 (en) 1991-05-08 1992-05-08 Hcv genomic sequences for diagnostics and therapeutics

Publications (2)

Publication Number Publication Date
BG98200A BG98200A (bg) 1995-01-31
BG62142B1 true BG62142B1 (bg) 1999-03-31

Family

ID=24800701

Family Applications (3)

Application Number Title Priority Date Filing Date
BG98200A BG62142B1 (bg) 1991-05-08 1993-11-05 Нсv геномни последователности за диагностика и лечение
BG101876A BG64627B1 (bg) 1991-05-08 1993-11-05 Нсv геномни последователности за диагностика и лечение
BG101876A BG101876A (en) 1991-05-08 1997-09-04 Hcv genome sequences for diagnostics and treatment

Family Applications After (2)

Application Number Title Priority Date Filing Date
BG101876A BG64627B1 (bg) 1991-05-08 1993-11-05 Нсv геномни последователности за диагностика и лечение
BG101876A BG101876A (en) 1991-05-08 1997-09-04 Hcv genome sequences for diagnostics and treatment

Country Status (20)

Country Link
EP (2) EP1394256A3 (pt)
JP (7) JPH06508026A (pt)
KR (1) KR100193801B1 (pt)
AT (1) ATE252154T1 (pt)
BG (3) BG62142B1 (pt)
CA (1) CA2108466C (pt)
CZ (2) CZ288722B6 (pt)
DE (1) DE69233234T2 (pt)
DK (1) DK0585398T3 (pt)
ES (1) ES2207633T3 (pt)
FI (1) FI115725B (pt)
HU (1) HU227548B1 (pt)
IE (1) IE921482A1 (pt)
NO (1) NO309532B1 (pt)
PL (2) PL170151B1 (pt)
PT (1) PT100472B (pt)
RO (1) RO117267B1 (pt)
RU (1) RU2155228C2 (pt)
SK (1) SK284205B6 (pt)
WO (1) WO1992019743A2 (pt)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5428145A (en) * 1991-08-09 1995-06-27 Immuno Japan, Inc. Non-A, non-B, hepatitis virus genome, polynucleotides, polypeptides, antigen, antibody and detection systems
EP0532167A3 (en) * 1991-08-09 1993-03-31 Immuno Japan Inc. Non-a, non-b hepatitis virus genome, polynucleotides, polypeptides, antigen, antibody and detection systems
US5427909A (en) * 1991-09-09 1995-06-27 Immuno Japan Inc. Oligonucleotides and determination system of HCV genotypes
JP3688290B2 (ja) * 1991-11-21 2005-08-24 コモン サーヴィシス エージェンシー C型肝炎ウイルス検査
US6667387B1 (en) 1996-09-30 2003-12-23 N.V. Innogenetics S.A. HCV core peptides
US6709828B1 (en) 1992-03-06 2004-03-23 N.V. Innogenetics S.A. Process for the determination of peptides corresponding to immunologically important epitopes and their use in a process for determination of antibodies or biotinylated peptides corresponding to immunologically important epitopes, a process for preparing them and compositions containing them
AU4387193A (en) * 1992-05-29 1993-12-30 Abbott Laboratories Ligase chain reaction starting with rna sequences
DK0662157T3 (da) * 1992-09-10 2001-08-27 Isis Pharmaceuticals Inc Præparater og fremgangsmåde til behandling af Hepatitis C-virus-associerede sygdomme
US6423489B1 (en) * 1992-09-10 2002-07-23 Isis Pharmaceuticals, Inc. Compositions and methods for treatment of Hepatitis C virus-associated diseases
US7258977B1 (en) 1992-11-27 2007-08-21 Innogenetics N.V. Process for typing of HCV isolates
JPH06153961A (ja) * 1992-11-27 1994-06-03 Imuno Japan:Kk C型肝炎ウイルス部分遺伝子、ならびにc型肝炎ウイルス遺 伝子の高感度検出法
AU681612B2 (en) * 1992-11-27 1997-09-04 N.V. Innogenetics S.A. Process for typing of hcv isolates
US7255997B1 (en) 1993-04-27 2007-08-14 N.V. Innogenetics S.A. Sequences of hepatitis C virus genotypes and their use as therapeutic and diagnostic agents
ATE373093T1 (de) 1993-04-27 2007-09-15 Innogenetics Nv Sequenzen der genotype des hepatitis-c-virus sowie ihre verwendung als arzneimitteln und diagnostika
JPH0775585A (ja) * 1993-06-14 1995-03-20 Immuno Japan:Kk C型肝炎ウイルス関連オリゴヌクレオチドならびにc型肝炎 ウイルス遺伝子型判定方法
US5882852A (en) * 1993-06-29 1999-03-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Hepatitic C virus (HCV) core gene nucleotide sequences and related methods of detecting major and minor genotypes of HCV isolates
US7070790B1 (en) 1993-06-29 2006-07-04 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 and core genes of isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
US5514539A (en) * 1993-06-29 1996-05-07 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 gene of 51 isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
EP0729973A4 (en) * 1993-10-29 1998-12-30 Srl Inc AN ANTIQUE PEPTIDE COMPOUND AND IMMUNOASSAY PROCEDURE
WO1995030746A1 (en) * 1994-05-10 1995-11-16 The General Hospital Corporation Antisense inhibition of hepatitis c virus
US7129337B1 (en) 1994-10-21 2006-10-31 Innogenetics N.V. Sequences of hepatitis C virus genotypes and their use as prophylactic, therapeutic and diagnostic agents
US5851759A (en) * 1996-04-19 1998-12-22 Chiron Corporation Heteroduplex tracking assay (HTA) for genotyping HCV
IT1284847B1 (it) * 1996-06-07 1998-05-22 Sorin Biomedica Diagnostics Sp Procedimento per la rivelazione di acidi nucleici specifici di hcv
JP2002505071A (ja) 1997-11-04 2002-02-19 ロシュ ダイアグノスティックス ゲーエムベーハー 特異的かつ高感度な核酸検出方法
US6680059B2 (en) 2000-08-29 2004-01-20 Tripep Ab Vaccines containing ribavirin and methods of use thereof
US6858590B2 (en) 2000-08-17 2005-02-22 Tripep Ab Vaccines containing ribavirin and methods of use thereof
US7022830B2 (en) 2000-08-17 2006-04-04 Tripep Ab Hepatitis C virus codon optimized non-structural NS3/4A fusion gene
ATE375804T1 (de) 2000-08-17 2007-11-15 Tripep Ab Ribavirin-enthaltende vakzine
US6586584B2 (en) 2001-01-29 2003-07-01 Becton, Dickinson And Company Sequences and methods for detection of Hepatitis C virus
US7196183B2 (en) 2001-08-31 2007-03-27 Innogenetics N.V. Hepatitis C virus genotype, and its use as prophylactic, therapeutic and diagnostic agent
US8124747B2 (en) 2003-08-29 2012-02-28 Innogenetics HCV clade and prototype sequences thereof
CN1977050B (zh) 2004-01-07 2012-09-05 第三次浪潮技术公司 丙型肝炎病毒基因型的确定
KR100733186B1 (ko) * 2005-05-31 2007-06-27 재단법인 목암생명공학연구소 Hcv 유전자에 특이적인 작은 간섭 rna 및 그를유효성분으로 포함하는 c형 간염 치료제
EP2185195A2 (en) 2007-08-16 2010-05-19 Tripep Ab Immunogen platform

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1049686C (zh) * 1987-11-18 2000-02-23 希龙股份有限公司 非a和非b肝炎病毒的诊断及疫苗
KR0185373B1 (ko) * 1989-03-17 1999-05-01 로버트 피. 블랙버언 Hcv 폴리단백질에서 유래되는 hcv 아미노산 서열 부분을 포함하는 폴리펩티드 및 그 사용
DK298190A (da) * 1989-12-18 1991-06-19 Wellcome Found Viralt middel
WO1991014779A1 (en) * 1990-03-28 1991-10-03 Mitsui Toatsu Chemicals, Incorporated Diagnostic for hepatitis virus
US5443965A (en) * 1990-04-06 1995-08-22 Genelabs Incorporated Hepatitis C virus epitopes
EP0933426A1 (en) * 1990-06-25 1999-08-04 The Research Foundation for Microbial Diseases of Osaka University Non-a, non-b hepatitis virus genomic cdna fragments and antigen polypeptides
CA2045326A1 (en) * 1990-06-25 1991-12-26 Hiroto Okayama Non-a, non-b, hepatitis virus particles
EP0510952A1 (en) * 1991-04-26 1992-10-28 Immuno Japan Inc. Oligonucleotide primers and their application for high-fidelity detection of non-a, non-b hepatitis virus

Also Published As

Publication number Publication date
PT100472B (pt) 1999-08-31
CA2108466A1 (en) 1992-11-09
RU2155228C2 (ru) 2000-08-27
AU668355B2 (en) 1996-05-02
ATE252154T1 (de) 2003-11-15
PT100472A (pt) 1993-08-31
NO309532B1 (no) 2001-02-12
CZ121096A3 (en) 1996-08-14
PL170151B1 (pl) 1996-10-31
BG101876A (en) 1998-11-30
HU227548B1 (en) 2011-08-29
JP2004290204A (ja) 2004-10-21
EP0585398B1 (en) 2003-10-15
HUT69609A (en) 1995-09-28
HU9303166D0 (en) 1994-03-28
IE921482A1 (en) 1992-11-18
DE69233234D1 (de) 2003-12-04
RO117267B1 (ro) 2001-12-28
DE69233234T2 (de) 2004-08-05
SK284205B6 (sk) 2004-10-05
JP2003024090A (ja) 2003-01-28
DK0585398T3 (da) 2004-02-02
CZ237793A3 (en) 1994-04-13
BG98200A (bg) 1995-01-31
BG64627B1 (bg) 2005-09-30
NO934019L (no) 1993-11-05
WO1992019743A3 (en) 1993-11-25
CZ288722B6 (cs) 2001-08-15
JP2003009893A (ja) 2003-01-14
FI115725B (fi) 2005-06-30
ES2207633T3 (es) 2004-06-01
SK123293A3 (en) 1994-06-08
NO934019D0 (no) 1993-11-05
JPH06508026A (ja) 1994-09-14
EP1394256A2 (en) 2004-03-03
JP2003009892A (ja) 2003-01-14
AU2155892A (en) 1992-12-21
WO1992019743A2 (en) 1992-11-12
PL169880B1 (pl) 1996-09-30
EP0585398A1 (en) 1994-03-09
EP1394256A3 (en) 2008-03-12
KR100193801B1 (ko) 1999-06-15
CZ288720B6 (cs) 2001-08-15
CA2108466C (en) 2007-07-10
FI934937A (fi) 1994-01-05
JP2003009891A (ja) 2003-01-14
FI934937A0 (fi) 1993-11-08
JP2008178416A (ja) 2008-08-07

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