BG61944B1 - Тилидиндихидрогенортофосфат, метод за неговото получаване ифармацевтични форми, които го съдържат - Google Patents

Тилидиндихидрогенортофосфат, метод за неговото получаване ифармацевтични форми, които го съдържат Download PDF

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Publication number
BG61944B1
BG61944B1 BG99565A BG9956595A BG61944B1 BG 61944 B1 BG61944 B1 BG 61944B1 BG 99565 A BG99565 A BG 99565A BG 9956595 A BG9956595 A BG 9956595A BG 61944 B1 BG61944 B1 BG 61944B1
Authority
BG
Bulgaria
Prior art keywords
tilidine
dihydrogenorthophosphate
preparation
salt
solid
Prior art date
Application number
BG99565A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG99565A (bg
Inventor
Wolfgang Herrmann
Armin Knapp
Hans Klausmann
Joachim Witzke
Original Assignee
Goedecke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Goedecke Ag filed Critical Goedecke Ag
Publication of BG99565A publication Critical patent/BG99565A/bg
Publication of BG61944B1 publication Critical patent/BG61944B1/bg

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C229/48—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups and carboxyl groups bound to carbon atoms of the same non-condensed ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BG99565A 1992-10-26 1995-04-12 Тилидиндихидрогенортофосфат, метод за неговото получаване ифармацевтични форми, които го съдържат BG61944B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4236074 1992-10-26
PCT/EP1993/002954 WO1994010129A1 (de) 1992-10-26 1993-10-25 Tilidin-dihydrogenorthophosphat, verfahren zu dessen herstellung und dieses enthaltende pharmazeutische zubereitungen

Publications (2)

Publication Number Publication Date
BG99565A BG99565A (bg) 1996-01-31
BG61944B1 true BG61944B1 (bg) 1998-10-30

Family

ID=6471354

Family Applications (1)

Application Number Title Priority Date Filing Date
BG99565A BG61944B1 (bg) 1992-10-26 1995-04-12 Тилидиндихидрогенортофосфат, метод за неговото получаване ифармацевтични форми, които го съдържат

Country Status (24)

Country Link
US (1) US5693669A (fi)
EP (1) EP0665830B1 (fi)
JP (1) JP3266261B2 (fi)
KR (1) KR100310041B1 (fi)
AT (1) ATE150004T1 (fi)
AU (1) AU683229B2 (fi)
BG (1) BG61944B1 (fi)
CA (1) CA2147759C (fi)
CZ (1) CZ285637B6 (fi)
DE (1) DE59305805D1 (fi)
DK (1) DK0665830T3 (fi)
ES (1) ES2098792T3 (fi)
FI (1) FI113642B (fi)
GR (1) GR3023186T3 (fi)
HU (1) HU219344B (fi)
MX (1) MX9306607A (fi)
NO (1) NO306395B1 (fi)
NZ (1) NZ257338A (fi)
PL (2) PL174197B1 (fi)
RO (1) RO112851B1 (fi)
RU (1) RU2123998C1 (fi)
SK (1) SK281041B6 (fi)
UA (1) UA42704C2 (fi)
WO (1) WO1994010129A1 (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE210983T1 (de) * 1997-11-03 2002-01-15 Stada Arzneimittel Ag Stabilisiertes kombinationsarzneimittel enthaltend naloxone und ein opiatanalgetikum
ATE242760T1 (de) * 1998-04-28 2003-06-15 Russinsky Ltd Tilidin-mesylat, verfahren zu dessen herstellung und pharmazeutische zusammensetzungen
ATE261302T1 (de) * 1998-05-28 2004-03-15 Krewel Meuselbach Gmbh Retardiertes schmerzmittel enthaltend tilidin
DE19859636A1 (de) * 1998-12-23 2000-06-29 Hexal Ag Kontrolliert freisetzende pharmazeutische Zusammensetzung mit Tilidinmesylat als Wirkstoff
DE19915602A1 (de) * 1999-04-07 2000-10-19 Gruenenthal Gmbh 3-Amino-4-arylpropan-1-ol-Derivate, deren Herstellung und Verwendung
DE29908435U1 (de) * 1999-05-11 1999-08-05 Krewel Meuselbach GmbH, 53783 Eitorf Dosiervorrichtung
DE50303646D1 (de) * 2002-06-28 2006-07-20 Stada Arzneimittel Ag Feste pharmazeutische Zusammensetzung enthaltend Tilidinhydrochlorid
DE10233108A1 (de) * 2002-07-20 2004-01-29 Krewel Meuselbach Gmbh Retardiertes Schmerzmittel enthaltend Tilidin und ein Lichtschutzmittel
DE10300325A1 (de) 2003-01-09 2004-07-22 Hexal Ag Granulat mit öliger Substanz, Herstellungsverfahren und Tablette
EP2168945A1 (en) 2008-09-26 2010-03-31 Hexal Ag Crystalline forms of Tilidine Mesylate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1793571B1 (de) * 1965-11-19 1971-12-30 Goedecke Ag 3t-Dimethylamino-4-phenyl-4t-carbaethoxy-delta?-cyclohexen und dessen Hydrochlorid
FR5978M (fi) * 1965-11-19 1968-04-22
US4933438A (en) * 1984-02-29 1990-06-12 University Of Florida Brain-specific analogues of centrally acting amines
US4800083A (en) * 1986-10-20 1989-01-24 R. P. Scherer Corporation Sustained release method and product
US5478577A (en) * 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level

Also Published As

Publication number Publication date
FI951961A0 (fi) 1995-04-25
DE59305805D1 (de) 1997-04-17
KR100310041B1 (ko) 2002-04-24
AU683229B2 (en) 1997-11-06
JP3266261B2 (ja) 2002-03-18
JPH08502505A (ja) 1996-03-19
UA42704C2 (uk) 2001-11-15
MX9306607A (es) 1994-04-29
SK52895A3 (en) 1995-12-06
SK281041B6 (sk) 2000-11-07
NO951532L (no) 1995-04-21
ATE150004T1 (de) 1997-03-15
NO306395B1 (no) 1999-11-01
CZ285637B6 (cs) 1999-10-13
EP0665830B1 (de) 1997-03-12
CA2147759C (en) 2004-08-10
FI113642B (fi) 2004-05-31
NZ257338A (en) 1996-03-26
BG99565A (bg) 1996-01-31
HU9501170D0 (en) 1995-06-28
HU219344B (en) 2001-03-28
PL308358A1 (en) 1995-07-24
US5693669A (en) 1997-12-02
RO112851B1 (ro) 1998-01-30
RU95113437A (ru) 1997-02-20
NO951532D0 (no) 1995-04-21
RU2123998C1 (ru) 1998-12-27
PL174739B1 (pl) 1998-09-30
FI951961A (fi) 1995-04-25
DK0665830T3 (da) 1997-09-01
WO1994010129A1 (de) 1994-05-11
HUT73787A (en) 1996-09-30
EP0665830A1 (de) 1995-08-09
ES2098792T3 (es) 1997-05-01
GR3023186T3 (en) 1997-07-30
CZ105295A3 (en) 1995-10-18
AU5370894A (en) 1994-05-24
KR950703518A (ko) 1995-09-20
PL174197B1 (pl) 1998-06-30
CA2147759A1 (en) 1994-05-11

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