MX9306607A - Dindihidrogeno-otorfosfato de tilidina, procedimiento para su obtencion y las preparaciones farmaceuticas que lo contienen. - Google Patents

Dindihidrogeno-otorfosfato de tilidina, procedimiento para su obtencion y las preparaciones farmaceuticas que lo contienen.

Info

Publication number
MX9306607A
MX9306607A MX9306607A MX9306607A MX9306607A MX 9306607 A MX9306607 A MX 9306607A MX 9306607 A MX9306607 A MX 9306607A MX 9306607 A MX9306607 A MX 9306607A MX 9306607 A MX9306607 A MX 9306607A
Authority
MX
Mexico
Prior art keywords
tilidine
pct
otorphosphate
dindihydrogen
procedure
Prior art date
Application number
MX9306607A
Other languages
English (en)
Inventor
Wolfgang Herrmann
Armin Knapp
Hans Klausmann
Original Assignee
Goedecke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Goedecke Ag filed Critical Goedecke Ag
Publication of MX9306607A publication Critical patent/MX9306607A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C229/48—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups and carboxyl groups bound to carbon atoms of the same non-condensed ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

Se describe una sal de tilidina especial menteadecuado para la obtención de formas de medicamento sólidos especialmente retardadas, tales como tabletas, grageas o cápsulas, debido a su estabilidad inesperada, concretamente el dihidrógeno- ortofosfato de tilidina.
MX9306607A 1992-10-26 1993-10-25 Dindihidrogeno-otorfosfato de tilidina, procedimiento para su obtencion y las preparaciones farmaceuticas que lo contienen. MX9306607A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4236074 1992-10-26

Publications (1)

Publication Number Publication Date
MX9306607A true MX9306607A (es) 1994-04-29

Family

ID=6471354

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9306607A MX9306607A (es) 1992-10-26 1993-10-25 Dindihidrogeno-otorfosfato de tilidina, procedimiento para su obtencion y las preparaciones farmaceuticas que lo contienen.

Country Status (24)

Country Link
US (1) US5693669A (es)
EP (1) EP0665830B1 (es)
JP (1) JP3266261B2 (es)
KR (1) KR100310041B1 (es)
AT (1) ATE150004T1 (es)
AU (1) AU683229B2 (es)
BG (1) BG61944B1 (es)
CA (1) CA2147759C (es)
CZ (1) CZ285637B6 (es)
DE (1) DE59305805D1 (es)
DK (1) DK0665830T3 (es)
ES (1) ES2098792T3 (es)
FI (1) FI113642B (es)
GR (1) GR3023186T3 (es)
HU (1) HU219344B (es)
MX (1) MX9306607A (es)
NO (1) NO306395B1 (es)
NZ (1) NZ257338A (es)
PL (2) PL174739B1 (es)
RO (1) RO112851B1 (es)
RU (1) RU2123998C1 (es)
SK (1) SK281041B6 (es)
UA (1) UA42704C2 (es)
WO (1) WO1994010129A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0913152B1 (de) * 1997-11-03 2001-12-19 Stada Arzneimittel Ag Stabilisiertes Kombinationsarzneimittel enthaltend Naloxone und ein Opiatanalgetikum
DE69908771T2 (de) * 1998-04-28 2004-04-22 Hexal Ag Tilidin-mesylat, verfahren zu dessen herstellung und pharmazeutische zusammensetzungen
EP0960619B1 (de) * 1998-05-28 2004-03-10 Krewel Meuselbach GmbH Retardiertes Schmerzmittel enthaltend Tilidin
DE19859636A1 (de) * 1998-12-23 2000-06-29 Hexal Ag Kontrolliert freisetzende pharmazeutische Zusammensetzung mit Tilidinmesylat als Wirkstoff
DE19915602A1 (de) * 1999-04-07 2000-10-19 Gruenenthal Gmbh 3-Amino-4-arylpropan-1-ol-Derivate, deren Herstellung und Verwendung
DE29908435U1 (de) * 1999-05-11 1999-08-05 Krewel Meuselbach GmbH, 53783 Eitorf Dosiervorrichtung
ATE328587T1 (de) * 2002-06-28 2006-06-15 Stada Arzneimittel Ag Feste pharmazeutische zusammensetzung enthaltend tilidinhydrochlorid
DE10233108A1 (de) * 2002-07-20 2004-01-29 Krewel Meuselbach Gmbh Retardiertes Schmerzmittel enthaltend Tilidin und ein Lichtschutzmittel
DE10300325A1 (de) 2003-01-09 2004-07-22 Hexal Ag Granulat mit öliger Substanz, Herstellungsverfahren und Tablette
EP2168945A1 (en) 2008-09-26 2010-03-31 Hexal Ag Crystalline forms of Tilidine Mesylate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR5978M (es) * 1965-11-19 1968-04-22
DE1793571B1 (de) * 1965-11-19 1971-12-30 Goedecke Ag 3t-Dimethylamino-4-phenyl-4t-carbaethoxy-delta?-cyclohexen und dessen Hydrochlorid
US4933438A (en) * 1984-02-29 1990-06-12 University Of Florida Brain-specific analogues of centrally acting amines
US4800083A (en) * 1986-10-20 1989-01-24 R. P. Scherer Corporation Sustained release method and product
US5478577A (en) * 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level

Also Published As

Publication number Publication date
HU219344B (en) 2001-03-28
UA42704C2 (uk) 2001-11-15
CA2147759A1 (en) 1994-05-11
JPH08502505A (ja) 1996-03-19
CA2147759C (en) 2004-08-10
PL174197B1 (pl) 1998-06-30
BG61944B1 (bg) 1998-10-30
AU5370894A (en) 1994-05-24
FI951961A0 (fi) 1995-04-25
DK0665830T3 (da) 1997-09-01
KR950703518A (ko) 1995-09-20
KR100310041B1 (ko) 2002-04-24
BG99565A (bg) 1996-01-31
GR3023186T3 (en) 1997-07-30
HU9501170D0 (en) 1995-06-28
SK52895A3 (en) 1995-12-06
FI113642B (fi) 2004-05-31
NO306395B1 (no) 1999-11-01
JP3266261B2 (ja) 2002-03-18
ATE150004T1 (de) 1997-03-15
EP0665830A1 (de) 1995-08-09
EP0665830B1 (de) 1997-03-12
AU683229B2 (en) 1997-11-06
CZ285637B6 (cs) 1999-10-13
PL308358A1 (en) 1995-07-24
CZ105295A3 (en) 1995-10-18
HUT73787A (en) 1996-09-30
NO951532D0 (no) 1995-04-21
PL174739B1 (pl) 1998-09-30
SK281041B6 (sk) 2000-11-07
RO112851B1 (ro) 1998-01-30
US5693669A (en) 1997-12-02
FI951961A (fi) 1995-04-25
WO1994010129A1 (de) 1994-05-11
DE59305805D1 (de) 1997-04-17
NO951532L (no) 1995-04-21
ES2098792T3 (es) 1997-05-01
NZ257338A (en) 1996-03-26
RU2123998C1 (ru) 1998-12-27
RU95113437A (ru) 1997-02-20

Similar Documents

Publication Publication Date Title
HUP0302131A2 (hu) Gyógyászati tramadolsók, ezeket tartalmazó gyógyszerkészítmények
GT199900069A (es) Preparaciones farmaceuticas estabilizadas de gabapentina y proceso para prepararla.
ID22746A (id) Senyawa-senyawa baru
HUP0000838A2 (hu) Szteroid-glikozidot tartalmazó extraktum, eljárás izolálására és szintetikus előállítására, valamint ezt tartalmazó étvágycsökkentő gyógyszerkészítmények
BR9406893A (pt) Emprego de nona- e decapeptideos para a preparação de um medicamento para o combate da aids
HUP0303082A2 (hu) Szubsztituált indolil-oxo-acetil-piperazinszármazékok, ezeket tartalmazó készítmények és vírusellenes alkalmazásuk
AR012125A1 (es) UNA SAL DE UN COMPUESTO DERIVADO DEL ÁCIDO NAFTIRIDINA CARBOXíLICO , SU USO PARA LA FABRICACIoN DE UN MEDICAMENTO , PROCEDIMIENTO PARA PREPARARLA Y UNA COMPOSICIoN FARMACÉUTICA QUE LO COMPRENDE
HUP9904092A2 (hu) Gyógyszerkészítmény HIV és rák kezelésére valamint eljárás előállítására
YU2494A (sh) Farmaceutska formulacija za tretiranje zavisnosti od nikotina
AR031117A1 (es) Uso de inhibidores de lipasa y secuestrantes de acido biliar para la preparacion de un medicamento, dicho inhibidor de lipasa y secuestrante de acido biliar y combinacion farmaceutica
MX9306607A (es) Dindihidrogeno-otorfosfato de tilidina, procedimiento para su obtencion y las preparaciones farmaceuticas que lo contienen.
DE69525649D1 (de) Lamotrigin haltiges arzneimittel
MX9308025A (es) Compuestos inhibidores de la proteasa del virus dela inmunodeficiencia humana, procedimiento para supreparacion y formulacion farmaceutica que los contiene.
BR9608392A (pt) Preparação multiparticulada de liberação controlada e forma de dosagem em tablete.
ATE151636T1 (de) Diphosphonsäuren und deren salze enthaltende arzneimittel
AU7775398A (en) Novel glycosylated ginkgolide derivatives, their application as medicines and pharmaceutical compositions
AR011437A1 (es) Composicion farmaceutica para el tratamiento de la migrana y el uso de la misma en la preparacion de un medicamento.
ES2151922T3 (es) Uso de aspirina para la fabricacion de un medicamento para mejorar la perfusion sanguinea en el utero.
IL82523A (en) Pharmaceutical composition comprising a surface-active compound and fluorinated compound capable of emitting ionic fluorine for inhibiting or destroying a unicellular living being or virus and inhibiting or destroying an enzyme associated with the being or virus
GEP20043377B (en) Pharmaceutical Complex
NO307933B1 (no) Vann-uløselig eller lite vannløselig terapeutisk forbindelse, anvendelse derav samt farmasøytisk blanding inneholdende nevnte forbindelse
HRPK20030006B1 (en) Pharmaceutical disinfective preparations on the basis of usnic acid sodium salt and medical plants and process for their obtaining
ES2138668T3 (es) Nuevos derivados de peptidos terapeuticamente activos en la cadena de coagulacion sanguinea, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
AR015724A1 (es) La utilizacion de un inhibidor del intercambiador entre na+ y h+ para la preparacion de un medicamento destinado al tratamiento o a la profilaxia deenfermedades del sistema nervioso central.
MX9204419A (es) Inhibidor de la forfolipasa a2(pla2), procedimiento para su preparacion y formulado farmaceutico que lo contiene.