BG61366B2 - Използване на съединения на метокси алифатните киселини с индазол за получаване на фармацевтично средство за лечение на автоимунни заболявания - Google Patents
Използване на съединения на метокси алифатните киселини с индазол за получаване на фармацевтично средство за лечение на автоимунни заболявания Download PDFInfo
- Publication number
- BG61366B2 BG61366B2 BG098590A BG9859094A BG61366B2 BG 61366 B2 BG61366 B2 BG 61366B2 BG 098590 A BG098590 A BG 098590A BG 9859094 A BG9859094 A BG 9859094A BG 61366 B2 BG61366 B2 BG 61366B2
- Authority
- BG
- Bulgaria
- Prior art keywords
- compound
- formula
- preparation
- autoimmune
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Reproductive Health (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Steroid Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI911101A IT1253703B (it) | 1991-04-22 | 1991-04-22 | Uso di acidi metossi alcanoici dell'indazolo per preparare un farmaco attivo nel trattamento di malattie autoimmunitarie |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG61366B2 true BG61366B2 (bg) | 1997-06-30 |
Family
ID=11359721
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG098590A BG61366B2 (bg) | 1991-04-22 | 1994-02-25 | Използване на съединения на метокси алифатните киселини с индазол за получаване на фармацевтично средство за лечение на автоимунни заболявания |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5278183A (cs) |
| EP (1) | EP0510748B1 (cs) |
| JP (1) | JP3056879B2 (cs) |
| KR (1) | KR100210199B1 (cs) |
| AT (1) | ATE135573T1 (cs) |
| AU (1) | AU657524B2 (cs) |
| BG (1) | BG61366B2 (cs) |
| CA (1) | CA2066304C (cs) |
| CZ (1) | CZ280613B6 (cs) |
| DE (1) | DE69209128T2 (cs) |
| DK (1) | DK0510748T3 (cs) |
| IL (1) | IL101660A (cs) |
| IT (1) | IT1253703B (cs) |
| NZ (1) | NZ242392A (cs) |
| SK (1) | SK278546B6 (cs) |
| ZA (1) | ZA922740B (cs) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2723315B1 (fr) | 1994-08-02 | 1996-10-25 | Cird Galderma | Procede et composition pour stimuler la differenciation des cellules preadipocytaires et traitements therapeutiques associes |
| IT1276031B1 (it) * | 1995-10-31 | 1997-10-24 | Angelini Ricerche Spa | Composizione farmaceutica per il trattamento delle malattie autoimmuni |
| IT1293795B1 (it) | 1997-07-28 | 1999-03-10 | Angelini Ricerche Spa | Farmaco attivo nel ridurre la produzione di proteina mcp-1 |
| US7666867B2 (en) * | 2001-10-26 | 2010-02-23 | University Of Connecticut | Heteroindanes: a new class of potent cannabimimetic ligands |
| ITMI20062254A1 (it) * | 2006-11-24 | 2008-05-25 | Acraf | Uso di un acido metossi-alcanoico dell'indazolo per preparare una composizione farmaceutca |
| KR101581829B1 (ko) | 2008-03-07 | 2015-12-31 | 아지엔드 키미쉐 리유나이트 안젤리니 프란체스코 에이.씨.알.에이.에프. 에스.피.에이 | 1-벤질-3-하이드록시메틸인다졸 유도체들 및 mcp-1 및 cx3cr1의 발현을 기초로 한 질환들의 치료에서 이의 용도 |
| EP2262778B8 (en) | 2008-03-07 | 2020-01-01 | Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.p.A. | 1-benzyl-3-hydroxymethylindazole derivatives and use thereof in the treatment of diseases based on the expression of mcp-1, cx3cr1 and p40 |
| KR101581828B1 (ko) * | 2008-03-07 | 2015-12-31 | 아지엔드 키미쉐 리유나이트 안젤리니 프란체스코 에이.씨.알.에이.에프. 에스.피.에이 | 신규한 1-벤질-3-하이드록시메틸인다졸 유도체들 및 mcp-1, cx3cr1 및 p40의 발현을 기초로 한 질환들의 치료에서 이의 용도 |
| SG176885A1 (en) | 2009-08-03 | 2012-01-30 | Acraf | Process for the preparation of 1-benzyl-3-hydr0xymethyl-1h-indaz0le and its derivatives and required magnesium intermediates |
| UA108742C2 (uk) * | 2009-09-23 | 2015-06-10 | Фармацевтична композиція для лікування запальних захворювань, опосередкованих mcp-1 | |
| US8999292B2 (en) | 2012-05-01 | 2015-04-07 | Translatum Medicus Inc. | Methods for treating and diagnosing blinding eye diseases |
| EP3990433B1 (en) | 2019-06-25 | 2026-05-20 | Translatum Medicus Inc | PROCESSES FOR THE MANUFACTURE OF 2-((1-BENZYL-1H-INDAZOL-3-YL)METHOXY)-2-METHYLPROPANOIC ACID AND ITS DERIVATIVES |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1194564B (it) * | 1983-04-18 | 1988-09-22 | Acraf | Impiego del bendazac e dei suoi sali nel trattamento della retinite pigmentosa |
| DE3664036D1 (en) * | 1985-02-12 | 1989-07-27 | Acraf | (1-phenylmethyl-5-hydroxy-1h-indazol-3-yl)-oxyacetic acid and salts thereof for use as a medicament, and pharmaceutical compositions containing them |
| IT1230441B (it) * | 1989-02-07 | 1991-10-23 | Acraf | Eteri della serie dell'indazolo |
-
1991
- 1991-04-22 IT ITMI911101A patent/IT1253703B/it active IP Right Grant
-
1992
- 1992-04-11 DE DE69209128T patent/DE69209128T2/de not_active Expired - Lifetime
- 1992-04-11 AT AT92201037T patent/ATE135573T1/de active
- 1992-04-11 DK DK92201037.6T patent/DK0510748T3/da active
- 1992-04-11 EP EP92201037A patent/EP0510748B1/en not_active Expired - Lifetime
- 1992-04-14 AU AU14883/92A patent/AU657524B2/en not_active Expired
- 1992-04-14 ZA ZA922740A patent/ZA922740B/xx unknown
- 1992-04-14 US US07/868,311 patent/US5278183A/en not_active Expired - Lifetime
- 1992-04-16 CA CA002066304A patent/CA2066304C/en not_active Expired - Lifetime
- 1992-04-16 NZ NZ242392A patent/NZ242392A/en not_active IP Right Cessation
- 1992-04-21 IL IL10166092A patent/IL101660A/en not_active IP Right Cessation
- 1992-04-22 SK SK1227-92A patent/SK278546B6/sk not_active IP Right Cessation
- 1992-04-22 JP JP4102849A patent/JP3056879B2/ja not_active Expired - Lifetime
- 1992-04-22 KR KR1019920006797A patent/KR100210199B1/ko not_active Expired - Lifetime
- 1992-04-22 CZ CS921227A patent/CZ280613B6/cs not_active IP Right Cessation
-
1994
- 1994-02-25 BG BG098590A patent/BG61366B2/bg unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU1488392A (en) | 1992-10-29 |
| KR100210199B1 (ko) | 1999-07-15 |
| US5278183A (en) | 1994-01-11 |
| DE69209128T2 (de) | 1996-11-28 |
| SK278546B6 (en) | 1997-09-10 |
| CZ280613B6 (cs) | 1996-03-13 |
| ZA922740B (en) | 1992-12-30 |
| ITMI911101A0 (it) | 1991-04-22 |
| CS122792A3 (en) | 1992-11-18 |
| ATE135573T1 (de) | 1996-04-15 |
| JP3056879B2 (ja) | 2000-06-26 |
| CA2066304A1 (en) | 1992-10-23 |
| KR920019350A (ko) | 1992-11-19 |
| IL101660A (en) | 1996-08-04 |
| DK0510748T3 (da) | 1996-07-22 |
| CA2066304C (en) | 2005-06-21 |
| NZ242392A (en) | 1997-06-24 |
| EP0510748B1 (en) | 1996-03-20 |
| EP0510748A1 (en) | 1992-10-28 |
| AU657524B2 (en) | 1995-03-16 |
| JPH0640915A (ja) | 1994-02-15 |
| DE69209128D1 (de) | 1996-04-25 |
| ITMI911101A1 (it) | 1992-10-22 |
| IT1253703B (it) | 1995-08-23 |
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