BG61366B2 - Използване на съединения на метокси алифатните киселини с индазол за получаване на фармацевтично средство за лечение на автоимунни заболявания - Google Patents

Използване на съединения на метокси алифатните киселини с индазол за получаване на фармацевтично средство за лечение на автоимунни заболявания Download PDF

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Publication number
BG61366B2
BG61366B2 BG098590A BG9859094A BG61366B2 BG 61366 B2 BG61366 B2 BG 61366B2 BG 098590 A BG098590 A BG 098590A BG 9859094 A BG9859094 A BG 9859094A BG 61366 B2 BG61366 B2 BG 61366B2
Authority
BG
Bulgaria
Prior art keywords
compound
formula
preparation
autoimmune
treatment
Prior art date
Application number
BG098590A
Other languages
Bulgarian (bg)
English (en)
Inventor
Bruno Silvestrini
Original Assignee
Angelini Ricerche S.P.A. Societa'consortile
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angelini Ricerche S.P.A. Societa'consortile filed Critical Angelini Ricerche S.P.A. Societa'consortile
Publication of BG61366B2 publication Critical patent/BG61366B2/bg

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
BG098590A 1991-04-22 1994-02-25 Използване на съединения на метокси алифатните киселини с индазол за получаване на фармацевтично средство за лечение на автоимунни заболявания BG61366B2 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI911101A IT1253703B (it) 1991-04-22 1991-04-22 Uso di acidi metossi alcanoici dell'indazolo per preparare un farmaco attivo nel trattamento di malattie autoimmunitarie

Publications (1)

Publication Number Publication Date
BG61366B2 true BG61366B2 (bg) 1997-06-30

Family

ID=11359721

Family Applications (1)

Application Number Title Priority Date Filing Date
BG098590A BG61366B2 (bg) 1991-04-22 1994-02-25 Използване на съединения на метокси алифатните киселини с индазол за получаване на фармацевтично средство за лечение на автоимунни заболявания

Country Status (16)

Country Link
US (1) US5278183A (cs)
EP (1) EP0510748B1 (cs)
JP (1) JP3056879B2 (cs)
KR (1) KR100210199B1 (cs)
AT (1) ATE135573T1 (cs)
AU (1) AU657524B2 (cs)
BG (1) BG61366B2 (cs)
CA (1) CA2066304C (cs)
CZ (1) CZ280613B6 (cs)
DE (1) DE69209128T2 (cs)
DK (1) DK0510748T3 (cs)
IL (1) IL101660A (cs)
IT (1) IT1253703B (cs)
NZ (1) NZ242392A (cs)
SK (1) SK278546B6 (cs)
ZA (1) ZA922740B (cs)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2723315B1 (fr) 1994-08-02 1996-10-25 Cird Galderma Procede et composition pour stimuler la differenciation des cellules preadipocytaires et traitements therapeutiques associes
IT1276031B1 (it) * 1995-10-31 1997-10-24 Angelini Ricerche Spa Composizione farmaceutica per il trattamento delle malattie autoimmuni
IT1293795B1 (it) 1997-07-28 1999-03-10 Angelini Ricerche Spa Farmaco attivo nel ridurre la produzione di proteina mcp-1
US7666867B2 (en) * 2001-10-26 2010-02-23 University Of Connecticut Heteroindanes: a new class of potent cannabimimetic ligands
ITMI20062254A1 (it) * 2006-11-24 2008-05-25 Acraf Uso di un acido metossi-alcanoico dell'indazolo per preparare una composizione farmaceutca
KR101581829B1 (ko) 2008-03-07 2015-12-31 아지엔드 키미쉐 리유나이트 안젤리니 프란체스코 에이.씨.알.에이.에프. 에스.피.에이 1-벤질-3-하이드록시메틸인다졸 유도체들 및 mcp-1 및 cx3cr1의 발현을 기초로 한 질환들의 치료에서 이의 용도
EP2262778B8 (en) 2008-03-07 2020-01-01 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.p.A. 1-benzyl-3-hydroxymethylindazole derivatives and use thereof in the treatment of diseases based on the expression of mcp-1, cx3cr1 and p40
KR101581828B1 (ko) * 2008-03-07 2015-12-31 아지엔드 키미쉐 리유나이트 안젤리니 프란체스코 에이.씨.알.에이.에프. 에스.피.에이 신규한 1-벤질-3-하이드록시메틸인다졸 유도체들 및 mcp-1, cx3cr1 및 p40의 발현을 기초로 한 질환들의 치료에서 이의 용도
SG176885A1 (en) 2009-08-03 2012-01-30 Acraf Process for the preparation of 1-benzyl-3-hydr0xymethyl-1h-indaz0le and its derivatives and required magnesium intermediates
UA108742C2 (uk) * 2009-09-23 2015-06-10 Фармацевтична композиція для лікування запальних захворювань, опосередкованих mcp-1
US8999292B2 (en) 2012-05-01 2015-04-07 Translatum Medicus Inc. Methods for treating and diagnosing blinding eye diseases
EP3990433B1 (en) 2019-06-25 2026-05-20 Translatum Medicus Inc PROCESSES FOR THE MANUFACTURE OF 2-((1-BENZYL-1H-INDAZOL-3-YL)METHOXY)-2-METHYLPROPANOIC ACID AND ITS DERIVATIVES

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1194564B (it) * 1983-04-18 1988-09-22 Acraf Impiego del bendazac e dei suoi sali nel trattamento della retinite pigmentosa
DE3664036D1 (en) * 1985-02-12 1989-07-27 Acraf (1-phenylmethyl-5-hydroxy-1h-indazol-3-yl)-oxyacetic acid and salts thereof for use as a medicament, and pharmaceutical compositions containing them
IT1230441B (it) * 1989-02-07 1991-10-23 Acraf Eteri della serie dell'indazolo

Also Published As

Publication number Publication date
AU1488392A (en) 1992-10-29
KR100210199B1 (ko) 1999-07-15
US5278183A (en) 1994-01-11
DE69209128T2 (de) 1996-11-28
SK278546B6 (en) 1997-09-10
CZ280613B6 (cs) 1996-03-13
ZA922740B (en) 1992-12-30
ITMI911101A0 (it) 1991-04-22
CS122792A3 (en) 1992-11-18
ATE135573T1 (de) 1996-04-15
JP3056879B2 (ja) 2000-06-26
CA2066304A1 (en) 1992-10-23
KR920019350A (ko) 1992-11-19
IL101660A (en) 1996-08-04
DK0510748T3 (da) 1996-07-22
CA2066304C (en) 2005-06-21
NZ242392A (en) 1997-06-24
EP0510748B1 (en) 1996-03-20
EP0510748A1 (en) 1992-10-28
AU657524B2 (en) 1995-03-16
JPH0640915A (ja) 1994-02-15
DE69209128D1 (de) 1996-04-25
ITMI911101A1 (it) 1992-10-22
IT1253703B (it) 1995-08-23

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