DE69209128D1 - Verwendung von Indazol-Methoxyalkansäure zur Herstellung eines Arzneimittels zur Behandlung von Autoimmunkrankheiten - Google Patents
Verwendung von Indazol-Methoxyalkansäure zur Herstellung eines Arzneimittels zur Behandlung von AutoimmunkrankheitenInfo
- Publication number
- DE69209128D1 DE69209128D1 DE69209128T DE69209128T DE69209128D1 DE 69209128 D1 DE69209128 D1 DE 69209128D1 DE 69209128 T DE69209128 T DE 69209128T DE 69209128 T DE69209128 T DE 69209128T DE 69209128 D1 DE69209128 D1 DE 69209128D1
- Authority
- DE
- Germany
- Prior art keywords
- medicament
- manufacture
- treatment
- autoimmune diseases
- indazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI911101A IT1253703B (it) | 1991-04-22 | 1991-04-22 | Uso di acidi metossi alcanoici dell'indazolo per preparare un farmaco attivo nel trattamento di malattie autoimmunitarie |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69209128D1 true DE69209128D1 (de) | 1996-04-25 |
DE69209128T2 DE69209128T2 (de) | 1996-11-28 |
Family
ID=11359721
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69209128T Expired - Lifetime DE69209128T2 (de) | 1991-04-22 | 1992-04-11 | Verwendung von Indazol-Methoxyalkansäure zur Herstellung eines Arzneimittels zur Behandlung von Autoimmunkrankheiten |
Country Status (16)
Country | Link |
---|---|
US (1) | US5278183A (de) |
EP (1) | EP0510748B1 (de) |
JP (1) | JP3056879B2 (de) |
KR (1) | KR100210199B1 (de) |
AT (1) | ATE135573T1 (de) |
AU (1) | AU657524B2 (de) |
BG (1) | BG61366B2 (de) |
CA (1) | CA2066304C (de) |
CZ (1) | CZ280613B6 (de) |
DE (1) | DE69209128T2 (de) |
DK (1) | DK0510748T3 (de) |
IL (1) | IL101660A (de) |
IT (1) | IT1253703B (de) |
NZ (1) | NZ242392A (de) |
SK (1) | SK278546B6 (de) |
ZA (1) | ZA922740B (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2723315B1 (fr) * | 1994-08-02 | 1996-10-25 | Cird Galderma | Procede et composition pour stimuler la differenciation des cellules preadipocytaires et traitements therapeutiques associes |
IT1276031B1 (it) * | 1995-10-31 | 1997-10-24 | Angelini Ricerche Spa | Composizione farmaceutica per il trattamento delle malattie autoimmuni |
IT1293795B1 (it) | 1997-07-28 | 1999-03-10 | Angelini Ricerche Spa | Farmaco attivo nel ridurre la produzione di proteina mcp-1 |
JP2005510492A (ja) * | 2001-10-26 | 2005-04-21 | ユニバーシティ オブ コネチカット | 新規な種類の効力のあるカンナビミメティックリガンド |
ITMI20062254A1 (it) * | 2006-11-24 | 2008-05-25 | Acraf | Uso di un acido metossi-alcanoico dell'indazolo per preparare una composizione farmaceutca |
SI2262778T1 (sl) | 2008-03-07 | 2019-12-31 | Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. | 1-benzil-3-hidroksimetilindazolni derivati in njihova uporaba pri zdravljenju bolezni, na osnovi izražanja MCP-1, CXCR1 in P40 |
MX2010009624A (es) | 2008-03-07 | 2010-09-28 | Acraf | Derivados de 1-bencil-3-hidroximetilindazol y uso de los mismos en el tratamiento de enfermedades basadas en la expresion de mcp-1 y cx3cr1. |
ES2569330T3 (es) * | 2008-03-07 | 2016-05-10 | Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. | Derivados del 1-bencil-3-hidroximetilindazol y su utilización en el tratamiento de enfermedades basadas en la expresión de MCP-1, CX3CR1 |
SG176885A1 (en) | 2009-08-03 | 2012-01-30 | Acraf | Process for the preparation of 1-benzyl-3-hydr0xymethyl-1h-indaz0le and its derivatives and required magnesium intermediates |
UA108742C2 (uk) * | 2009-09-23 | 2015-06-10 | Фармацевтична композиція для лікування запальних захворювань, опосередкованих mcp-1 | |
US8999292B2 (en) | 2012-05-01 | 2015-04-07 | Translatum Medicus Inc. | Methods for treating and diagnosing blinding eye diseases |
WO2020261158A1 (en) | 2019-06-25 | 2020-12-30 | Translatum Medicus Inc. | Processes of making 2-((1-benzyl-1h-indazol-3-yl)methoxy)-2-methylpropanoic acid and its derivatives |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1194564B (it) * | 1983-04-18 | 1988-09-22 | Acraf | Impiego del bendazac e dei suoi sali nel trattamento della retinite pigmentosa |
EP0191520B1 (de) * | 1985-02-12 | 1989-06-21 | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A. | (1-Phenylmethyl-5-hydroxy-1H-indazol-3-yl)-oxyessigsäure und deren Salze zur Verwendung als Heilmittel und diese enthaltende pharmazeutische Zusammensetzungen |
IT1230441B (it) * | 1989-02-07 | 1991-10-23 | Acraf | Eteri della serie dell'indazolo |
-
1991
- 1991-04-22 IT ITMI911101A patent/IT1253703B/it active IP Right Grant
-
1992
- 1992-04-11 AT AT92201037T patent/ATE135573T1/de active
- 1992-04-11 EP EP92201037A patent/EP0510748B1/de not_active Expired - Lifetime
- 1992-04-11 DK DK92201037.6T patent/DK0510748T3/da active
- 1992-04-11 DE DE69209128T patent/DE69209128T2/de not_active Expired - Lifetime
- 1992-04-14 ZA ZA922740A patent/ZA922740B/xx unknown
- 1992-04-14 US US07/868,311 patent/US5278183A/en not_active Expired - Lifetime
- 1992-04-14 AU AU14883/92A patent/AU657524B2/en not_active Expired
- 1992-04-16 CA CA002066304A patent/CA2066304C/en not_active Expired - Lifetime
- 1992-04-16 NZ NZ242392A patent/NZ242392A/en not_active IP Right Cessation
- 1992-04-21 IL IL10166092A patent/IL101660A/en not_active IP Right Cessation
- 1992-04-22 SK SK1227-92A patent/SK278546B6/sk not_active IP Right Cessation
- 1992-04-22 KR KR1019920006797A patent/KR100210199B1/ko not_active IP Right Cessation
- 1992-04-22 CZ CS921227A patent/CZ280613B6/cs not_active IP Right Cessation
- 1992-04-22 JP JP4102849A patent/JP3056879B2/ja not_active Expired - Lifetime
-
1994
- 1994-02-25 BG BG098590A patent/BG61366B2/bg unknown
Also Published As
Publication number | Publication date |
---|---|
CZ280613B6 (cs) | 1996-03-13 |
US5278183A (en) | 1994-01-11 |
CA2066304A1 (en) | 1992-10-23 |
DK0510748T3 (da) | 1996-07-22 |
KR100210199B1 (ko) | 1999-07-15 |
JPH0640915A (ja) | 1994-02-15 |
ITMI911101A1 (it) | 1992-10-22 |
NZ242392A (en) | 1997-06-24 |
EP0510748A1 (de) | 1992-10-28 |
BG61366B2 (bg) | 1997-06-30 |
ATE135573T1 (de) | 1996-04-15 |
SK278546B6 (en) | 1997-09-10 |
AU1488392A (en) | 1992-10-29 |
JP3056879B2 (ja) | 2000-06-26 |
IT1253703B (it) | 1995-08-23 |
AU657524B2 (en) | 1995-03-16 |
ITMI911101A0 (it) | 1991-04-22 |
DE69209128T2 (de) | 1996-11-28 |
IL101660A (en) | 1996-08-04 |
CS122792A3 (en) | 1992-11-18 |
ZA922740B (en) | 1992-12-30 |
EP0510748B1 (de) | 1996-03-20 |
KR920019350A (ko) | 1992-11-19 |
CA2066304C (en) | 2005-06-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR0010366A (pt) | Composto, composição farmacêutica, método de preparar um composto, e, composto para uso em terapia | |
ATE168007T1 (de) | Zur behandlung von erkrankungen des zentralnervensystems verwendbare benzimidazole | |
ATE231519T1 (de) | Dinukleotide zur verwendung in der behandlung von lungenkrankheiten | |
DE69903750D1 (de) | Verwendung von langkettigen n-alkyl derivaten von deoxynojirimycin zur herstellung eines medikaments zur behandlung von mit glykolipiden akkumulation zusammenhängenden krankheiten | |
DE69209128D1 (de) | Verwendung von Indazol-Methoxyalkansäure zur Herstellung eines Arzneimittels zur Behandlung von Autoimmunkrankheiten | |
NO303765B1 (no) | Anvendelse av et derivat av spirooksatiolankinuklidin ved fremstilling av et preparat for behandling av Sj°grens syndrom | |
ATE205712T1 (de) | Verwendung von 2-phenyl-3-aroylbenzothiophen derivaten zur herstellung eines medikaments zur hemmung der angiogenese und angiogene krankheiten | |
ATE199642T1 (de) | Verwendung von 2-phenyl-3-aroylbenzothiophen derivaten zur herstellung eines medikaments zur hemmung des knorpelabbaus | |
ATE79257T1 (de) | Verwendung von tetrahydrobenz(c,d>indol-6carboxamiden zur herstellung von arzneimitteln zur behandlung von angstzustaenden. | |
AU2868689A (en) | Use of 1,4-disubstituted-piperidinyl compounds in the manufacture of a medicament for the treatment of insomnia | |
WO1999004770A3 (en) | A pharmaceutical composition active in reducing production of mcp-1 protein | |
ATE85334T1 (de) | Bisphenylalkylpiperazin-derivate, verfahren zur herstellung und arzneimittelzubereitung. | |
KR950016720A (ko) | 아밀로이드 단백질의 효과를 저해하는 방법 | |
ATE31022T1 (de) | Verwendung von 4,5'-azo-bis-salicylsaeure zur herstellung eines arzneimittels zur behandlung entzuendlicher darmkrankheiten. | |
ATE181503T1 (de) | Verwendung von idazoxan und derivaten zur herstellung eines arzneimittels zur behandlung von parkinsonismus und seiner evolution | |
BR9708922A (pt) | Piridil-e pirimidil-piperazinas no tratamento de doenças causadas por substâncias usadas em excesso | |
DE68910010D1 (de) | Verwendung von Dapiprazol zur Herstellung eines Arzneimittels zur Verhinderung des Toleranzentwicklung bei der analgetischen Behandlung mit Morphin. | |
NO164170C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive 1-benzhydryl-4-cinnamyl-piperazinderivater. | |
ATE212842T1 (de) | Quinoxalin-derivate zur behandlung von tinnitus | |
NO912168L (no) | Fremgangsmaate for fremstilling av terapeutisk aktive piperazinderivater. | |
ATE81465T1 (de) | Verwendung von 2-oxo-imidazolidin-derivaten zur behandlung von nierenkrankheiten. | |
ATE81466T1 (de) | Verwendung von 2-oxo-imidazolidin-derivaten zur prophylaxe und zur behandlung von herzinsuffizienz. | |
AU2013888A (en) | Uricosuric composition | |
ATE105476T1 (de) | Dihydropyridin-verbindung zur verbesserung der adernausdehnung und hemmung der herzhypertrophie. | |
TH1930EX (th) | สารประกอบพิวรีบที่ต่อต้านเชื้อไวรัส |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |