DE69209128D1 - Verwendung von Indazol-Methoxyalkansäure zur Herstellung eines Arzneimittels zur Behandlung von Autoimmunkrankheiten - Google Patents

Verwendung von Indazol-Methoxyalkansäure zur Herstellung eines Arzneimittels zur Behandlung von Autoimmunkrankheiten

Info

Publication number
DE69209128D1
DE69209128D1 DE69209128T DE69209128T DE69209128D1 DE 69209128 D1 DE69209128 D1 DE 69209128D1 DE 69209128 T DE69209128 T DE 69209128T DE 69209128 T DE69209128 T DE 69209128T DE 69209128 D1 DE69209128 D1 DE 69209128D1
Authority
DE
Germany
Prior art keywords
medicament
manufacture
treatment
autoimmune diseases
indazole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69209128T
Other languages
English (en)
Other versions
DE69209128T2 (de
Inventor
Bruno Silvestrini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Angelini Ricerche SpA
Original Assignee
Angelini Ricerche SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angelini Ricerche SpA filed Critical Angelini Ricerche SpA
Publication of DE69209128D1 publication Critical patent/DE69209128D1/de
Application granted granted Critical
Publication of DE69209128T2 publication Critical patent/DE69209128T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69209128T 1991-04-22 1992-04-11 Verwendung von Indazol-Methoxyalkansäure zur Herstellung eines Arzneimittels zur Behandlung von Autoimmunkrankheiten Expired - Lifetime DE69209128T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI911101A IT1253703B (it) 1991-04-22 1991-04-22 Uso di acidi metossi alcanoici dell'indazolo per preparare un farmaco attivo nel trattamento di malattie autoimmunitarie

Publications (2)

Publication Number Publication Date
DE69209128D1 true DE69209128D1 (de) 1996-04-25
DE69209128T2 DE69209128T2 (de) 1996-11-28

Family

ID=11359721

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69209128T Expired - Lifetime DE69209128T2 (de) 1991-04-22 1992-04-11 Verwendung von Indazol-Methoxyalkansäure zur Herstellung eines Arzneimittels zur Behandlung von Autoimmunkrankheiten

Country Status (16)

Country Link
US (1) US5278183A (de)
EP (1) EP0510748B1 (de)
JP (1) JP3056879B2 (de)
KR (1) KR100210199B1 (de)
AT (1) ATE135573T1 (de)
AU (1) AU657524B2 (de)
BG (1) BG61366B2 (de)
CA (1) CA2066304C (de)
CZ (1) CZ280613B6 (de)
DE (1) DE69209128T2 (de)
DK (1) DK0510748T3 (de)
IL (1) IL101660A (de)
IT (1) IT1253703B (de)
NZ (1) NZ242392A (de)
SK (1) SK278546B6 (de)
ZA (1) ZA922740B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2723315B1 (fr) * 1994-08-02 1996-10-25 Cird Galderma Procede et composition pour stimuler la differenciation des cellules preadipocytaires et traitements therapeutiques associes
IT1276031B1 (it) * 1995-10-31 1997-10-24 Angelini Ricerche Spa Composizione farmaceutica per il trattamento delle malattie autoimmuni
IT1293795B1 (it) 1997-07-28 1999-03-10 Angelini Ricerche Spa Farmaco attivo nel ridurre la produzione di proteina mcp-1
EP1448557A4 (de) * 2001-10-26 2005-02-02 Univ Connecticut Heteroindane: eine neue klasse hochwirksamer cannabimimetischer liganden
ITMI20062254A1 (it) 2006-11-24 2008-05-25 Acraf Uso di un acido metossi-alcanoico dell'indazolo per preparare una composizione farmaceutca
AU2009221063B2 (en) 2008-03-07 2013-03-21 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. 1-benzyl-3-hydroxymethylindazole derivatives and use thereof in the treatment of diseases based on the expression of MCP-1, and CX3CR1
LT2254869T (lt) 2008-03-07 2017-08-10 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. Nauji 1-benzil-3-hidroksimetilindazolo dariniai ir jų panaudojimas gydyme ligų, susijusių su cx3cr1 ir p40 raiška
US8461194B2 (en) 2008-03-07 2013-06-11 Aziende Chimiche Riunite Angelini Francesco A. C. R. A. F. S. P. A. 1-benzyl-3-hydroxymethylindazole derivatives and use thereof in the treatment of diseases based on the expression of MCP-1, CX3CR1 and P40
MX2012001520A (es) 2009-08-03 2012-06-01 Acraf Proceso para la preparacion de 1-bencil-3-hidroximetil-1h-indazol y sus derivados e intermediarios de magnesio requeridos.
UA108742C2 (uk) * 2009-09-23 2015-06-10 Фармацевтична композиція для лікування запальних захворювань, опосередкованих mcp-1
US8999292B2 (en) 2012-05-01 2015-04-07 Translatum Medicus Inc. Methods for treating and diagnosing blinding eye diseases
WO2020261158A1 (en) 2019-06-25 2020-12-30 Translatum Medicus Inc. Processes of making 2-((1-benzyl-1h-indazol-3-yl)methoxy)-2-methylpropanoic acid and its derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1194564B (it) * 1983-04-18 1988-09-22 Acraf Impiego del bendazac e dei suoi sali nel trattamento della retinite pigmentosa
EP0191520B1 (de) * 1985-02-12 1989-06-21 AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A. (1-Phenylmethyl-5-hydroxy-1H-indazol-3-yl)-oxyessigsäure und deren Salze zur Verwendung als Heilmittel und diese enthaltende pharmazeutische Zusammensetzungen
IT1230441B (it) * 1989-02-07 1991-10-23 Acraf Eteri della serie dell'indazolo

Also Published As

Publication number Publication date
EP0510748A1 (de) 1992-10-28
CS122792A3 (en) 1992-11-18
CA2066304C (en) 2005-06-21
BG61366B2 (bg) 1997-06-30
NZ242392A (en) 1997-06-24
IL101660A (en) 1996-08-04
CA2066304A1 (en) 1992-10-23
IT1253703B (it) 1995-08-23
ATE135573T1 (de) 1996-04-15
AU1488392A (en) 1992-10-29
SK278546B6 (en) 1997-09-10
ITMI911101A1 (it) 1992-10-22
KR920019350A (ko) 1992-11-19
ITMI911101A0 (it) 1991-04-22
DK0510748T3 (da) 1996-07-22
JPH0640915A (ja) 1994-02-15
DE69209128T2 (de) 1996-11-28
KR100210199B1 (ko) 1999-07-15
CZ280613B6 (cs) 1996-03-13
AU657524B2 (en) 1995-03-16
ZA922740B (en) 1992-12-30
US5278183A (en) 1994-01-11
EP0510748B1 (de) 1996-03-20
JP3056879B2 (ja) 2000-06-26

Similar Documents

Publication Publication Date Title
BR0010366A (pt) Composto, composição farmacêutica, método de preparar um composto, e, composto para uso em terapia
ATE168007T1 (de) Zur behandlung von erkrankungen des zentralnervensystems verwendbare benzimidazole
DE69209128T2 (de) Verwendung von Indazol-Methoxyalkansäure zur Herstellung eines Arzneimittels zur Behandlung von Autoimmunkrankheiten
NO303765B1 (no) Anvendelse av et derivat av spirooksatiolankinuklidin ved fremstilling av et preparat for behandling av Sj°grens syndrom
ATE205712T1 (de) Verwendung von 2-phenyl-3-aroylbenzothiophen derivaten zur herstellung eines medikaments zur hemmung der angiogenese und angiogene krankheiten
ATE199642T1 (de) Verwendung von 2-phenyl-3-aroylbenzothiophen derivaten zur herstellung eines medikaments zur hemmung des knorpelabbaus
DE3888340T2 (de) Verwendung von 1,4-disubstituierten-Piperidinyl-Verbindungen zur Herstellung eines Arzneimittels zur Behandlung von Schlaflosigkeit.
ATE79257T1 (de) Verwendung von tetrahydrobenz(c,d>indol-6carboxamiden zur herstellung von arzneimitteln zur behandlung von angstzustaenden.
DE69501359D1 (de) Verwendung von Phosphatdiestern zur Behandlung von Erkrankungen der Retina
WO1999004770A3 (en) A pharmaceutical composition active in reducing production of mcp-1 protein
KR950016720A (ko) 아밀로이드 단백질의 효과를 저해하는 방법
ATE181503T1 (de) Verwendung von idazoxan und derivaten zur herstellung eines arzneimittels zur behandlung von parkinsonismus und seiner evolution
BR9708922A (pt) Piridil-e pirimidil-piperazinas no tratamento de doenças causadas por substâncias usadas em excesso
DE68910010D1 (de) Verwendung von Dapiprazol zur Herstellung eines Arzneimittels zur Verhinderung des Toleranzentwicklung bei der analgetischen Behandlung mit Morphin.
NO164170C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 1-benzhydryl-4-cinnamyl-piperazinderivater.
NO912168L (no) Fremgangsmaate for fremstilling av terapeutisk aktive piperazinderivater.
ATE81465T1 (de) Verwendung von 2-oxo-imidazolidin-derivaten zur behandlung von nierenkrankheiten.
DE69429447T2 (de) Verwendung von 2-aminopurinderivaten zur behandlung und prophylaxe der menschlichen herpesvirus 7 infektionen
AU2013888A (en) Uricosuric composition
ATE105476T1 (de) Dihydropyridin-verbindung zur verbesserung der adernausdehnung und hemmung der herzhypertrophie.
TH1930EX (th) สารประกอบพิวรีบที่ต่อต้านเชื้อไวรัส

Legal Events

Date Code Title Description
8364 No opposition during term of opposition