BG49047A3 - Метод за получаване на 1,5-бензотиазепинови производни - Google Patents
Метод за получаване на 1,5-бензотиазепинови производниInfo
- Publication number
- BG49047A3 BG49047A3 BG085117A BG8511788A BG49047A3 BG 49047 A3 BG49047 A3 BG 49047A3 BG 085117 A BG085117 A BG 085117A BG 8511788 A BG8511788 A BG 8511788A BG 49047 A3 BG49047 A3 BG 49047A3
- Authority
- BG
- Bulgaria
- Prior art keywords
- group
- hydrogen
- acetyl
- obtaining
- methyl
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- KJFRSZASZNLCDF-UHFFFAOYSA-N 1,5-benzothiazepine Chemical class S1C=CC=NC2=CC=CC=C12 KJFRSZASZNLCDF-UHFFFAOYSA-N 0.000 title 1
- 239000001257 hydrogen Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 208000014644 Brain disease Diseases 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- UEEJHVSXFDXPFK-UHFFFAOYSA-N N-dimethylaminoethanol Chemical compound CN(C)CCO UEEJHVSXFDXPFK-UHFFFAOYSA-N 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 125000004391 aryl sulfonyl group Chemical group 0.000 abstract 1
- 210000004556 brain Anatomy 0.000 abstract 1
- 239000000460 chlorine Chemical group 0.000 abstract 1
- 229910052801 chlorine Chemical group 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 229960002887 deanol Drugs 0.000 abstract 1
- 208000019622 heart disease Diseases 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000000020 sulfo group Chemical group O=S(=O)([*])O[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62208482A JPS6450872A (en) | 1987-08-21 | 1987-08-21 | Production of 1,5-benzothiazepine derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG49047A3 true BG49047A3 (bg) | 1991-07-15 |
Family
ID=16556895
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG085117A BG49047A3 (bg) | 1987-08-21 | 1988-08-02 | Метод за получаване на 1,5-бензотиазепинови производни |
Country Status (15)
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1236467A (en) * | 1967-10-28 | 1971-06-23 | Tanabe Seiyaku Co | Benzothiazepine derivatives |
| SE449611B (sv) * | 1982-07-09 | 1987-05-11 | Tanabe Seiyaku Co | Sett att framstella 1,5-bensotiazepinderivat |
| US4564612A (en) * | 1983-04-22 | 1986-01-14 | Takeda Chemical Industries, Ltd. | Condensed, seven-membered ring compounds and their use |
| US4567175A (en) * | 1983-06-03 | 1986-01-28 | Tanabe Seiyaku Co., Ltd. | 8-Chloro-1,5-benzothiazepine derivatives |
| GB8315364D0 (en) * | 1983-06-03 | 1983-07-06 | Tanabe Seiyaku Co | 8-chloro-1 5-benzothiazepine derivatives |
| GB8406318D0 (en) * | 1984-03-10 | 1984-04-11 | Tanabe Seiyaku Co | 1 5-benzothiazepine derivatives |
| JPS61103877A (ja) * | 1984-10-24 | 1986-05-22 | Tanabe Seiyaku Co Ltd | ベンゾチアゼピン誘導体及びその製法 |
| GB2167063A (en) * | 1984-11-17 | 1986-05-21 | Tanabe Seiyaku Co | 6 or 9-chloro-1, 5-benzothiazepine derivatives |
| JPS61225175A (ja) * | 1985-03-28 | 1986-10-06 | Sawai Seiyaku Kk | １，５−ベンゾチアゼピン誘導体の製造方法 |
| HU195795B (en) * | 1985-11-06 | 1988-07-28 | Richter Gedeon Vegyeszet | Process for preparing (2s,3s)-3-acetoxy-5-(n,n-dimethyl-amino-ethyl)-2-(h-methoxy-phenyl)-2,3-dihydro-1,5-benzothiazepin-h(5h)-one |
-
1987
- 1987-08-21 JP JP62208482A patent/JPS6450872A/ja active Pending
-
1988
- 1988-06-27 IE IE195088A patent/IE61169B1/en not_active IP Right Cessation
- 1988-06-29 FI FI883116A patent/FI93009C/fi not_active IP Right Cessation
- 1988-07-07 CA CA000571434A patent/CA1312077C/en not_active Expired - Lifetime
- 1988-07-07 IL IL8702688A patent/IL87026A/en not_active IP Right Cessation
- 1988-07-16 CN CN88104429A patent/CN1031374A/zh active Pending
- 1988-08-02 BG BG085117A patent/BG49047A3/xx unknown
- 1988-08-04 GR GR880100516A patent/GR1000452B/el unknown
- 1988-08-09 NO NO883526A patent/NO170541C/no unknown
- 1988-08-12 ES ES8802539A patent/ES2007993A6/es not_active Expired
- 1988-08-18 PT PT88300A patent/PT88300B/pt not_active IP Right Cessation
- 1988-08-19 AT AT0206388A patent/AT395424B/de not_active IP Right Cessation
- 1988-08-19 RU SU884356329A patent/RU1784041C/ru active
- 1988-08-20 KR KR1019880010577A patent/KR890003723A/ko not_active Ceased
-
1990
- 1990-05-07 TW TW079103691A patent/TW207536B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| CA1312077C (en) | 1992-12-29 |
| NO883526L (no) | 1989-02-22 |
| RU1784041C (ru) | 1992-12-23 |
| PT88300A (pt) | 1989-06-30 |
| NO170541B (no) | 1992-07-20 |
| FI93009C (fi) | 1995-02-10 |
| TW207536B (enrdf_load_html_response) | 1993-06-11 |
| FI883116A0 (fi) | 1988-06-29 |
| PT88300B (pt) | 1995-03-31 |
| FI93009B (fi) | 1994-10-31 |
| IL87026A0 (en) | 1988-12-30 |
| AT395424B (de) | 1992-12-28 |
| IE61169B1 (en) | 1994-10-05 |
| CN1031374A (zh) | 1989-03-01 |
| ES2007993A6 (es) | 1989-07-01 |
| IE881950L (en) | 1989-02-21 |
| FI883116A7 (fi) | 1989-02-22 |
| GR880100516A (en) | 1989-05-25 |
| NO883526D0 (no) | 1988-08-09 |
| ATA206388A (de) | 1992-05-15 |
| KR890003723A (ko) | 1989-04-17 |
| GR1000452B (el) | 1992-07-30 |
| IL87026A (en) | 1995-01-24 |
| JPS6450872A (en) | 1989-02-27 |
| NO170541C (no) | 1992-10-28 |
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