BG47036A3 - Method for preparing of monohydrate of beta- lactamic antibiotic 1- cpbacephalosporine - Google Patents
Method for preparing of monohydrate of beta- lactamic antibiotic 1- cpbacephalosporineInfo
- Publication number
- BG47036A3 BG47036A3 BG085594A BG8559488A BG47036A3 BG 47036 A3 BG47036 A3 BG 47036A3 BG 085594 A BG085594 A BG 085594A BG 8559488 A BG8559488 A BG 8559488A BG 47036 A3 BG47036 A3 BG 47036A3
- Authority
- BG
- Bulgaria
- Prior art keywords
- monohydrate
- cpbacephalosporine
- beta
- preparing
- lactamic
- Prior art date
Links
- 150000004682 monohydrates Chemical class 0.000 title abstract 2
- 230000003115 biocidal effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10576687A | 1987-10-06 | 1987-10-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
BG47036A3 true BG47036A3 (en) | 1990-04-16 |
Family
ID=22307671
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG085594A BG47036A3 (en) | 1987-10-06 | 1988-10-04 | Method for preparing of monohydrate of beta- lactamic antibiotic 1- cpbacephalosporine |
Country Status (32)
Country | Link |
---|---|
EP (1) | EP0311366B1 (xx) |
JP (1) | JP2641745B2 (xx) |
KR (1) | KR970002637B1 (xx) |
CN (1) | CN1029966C (xx) |
AR (1) | AR248407A1 (xx) |
AT (1) | ATE103916T1 (xx) |
AU (1) | AU598155B2 (xx) |
BG (1) | BG47036A3 (xx) |
CA (1) | CA1334970C (xx) |
CS (1) | CS270594B2 (xx) |
DD (1) | DD273634A5 (xx) |
DE (1) | DE3888913T2 (xx) |
DK (1) | DK170070B1 (xx) |
EG (1) | EG18529A (xx) |
ES (1) | ES2063049T3 (xx) |
FI (1) | FI884554A (xx) |
HK (1) | HK15497A (xx) |
HU (1) | HU206348B (xx) |
IE (1) | IE62108B1 (xx) |
IL (1) | IL87905A (xx) |
MX (1) | MX13277A (xx) |
MY (1) | MY104063A (xx) |
NO (1) | NO884416L (xx) |
NZ (1) | NZ226450A (xx) |
OA (1) | OA08958A (xx) |
PH (1) | PH31002A (xx) |
PL (1) | PL152022B1 (xx) |
PT (1) | PT88662B (xx) |
SU (1) | SU1731058A3 (xx) |
UA (1) | UA19149A (xx) |
YU (1) | YU46699B (xx) |
ZA (1) | ZA887409B (xx) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY103554A (en) * | 1987-10-07 | 1993-07-31 | Lilly Co Eli | Manohydrate and solvates of a new (beta)-lactam antibiotic. |
CA2002596A1 (en) * | 1988-11-14 | 1990-05-14 | Thomas M. Eckrich | Hydrates of b-lactam antibiotic |
CA2002597C (en) * | 1988-11-14 | 1999-03-23 | Thomas M. Eckrich | Solvates of b-lactam antibiotic |
CA2034592C (en) * | 1990-01-26 | 2001-06-05 | Ralph R. Pfeiffer | Crystalline hydrochloride of new beta-lactam antibiotic and process therefor |
US5374719A (en) * | 1993-06-04 | 1994-12-20 | Eli Lilly And Company | Process for converting loracarbef dihydrate to loracarbef monohydrate |
US5352782A (en) * | 1993-06-04 | 1994-10-04 | Eli Lilly And Company | Process for preparing crystalline β-lactam monohydrate |
US5399686A (en) * | 1993-06-04 | 1995-03-21 | Eli Lilly And Company | Loracarbef isopropanolate and a process for converting loracarbef isopropanolate to loracarbef monohydrate |
US5550231A (en) * | 1993-06-15 | 1996-08-27 | Eli Lilly And Company | Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof |
US5412094A (en) * | 1993-06-28 | 1995-05-02 | Eli Lilly And Company | Bicyclic beta-lactam/paraben complexes |
US5580977A (en) * | 1995-03-01 | 1996-12-03 | Eli Lilly And Company | Process for preparing loracarbef monohydrate |
US6001996A (en) * | 1995-05-11 | 1999-12-14 | Eli Lilly And Company | Complexes of cephalosporins and carbacephalosporins with parabens |
US7056906B2 (en) | 2001-09-21 | 2006-06-06 | Schering Corporation | Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women |
ES2318274T3 (es) | 2003-03-07 | 2009-05-01 | Schering Corporation | Compuestos de azetidinona sustituida, formulaciones y uso de los mismos para el tratamiento de hipercolesterolemia. |
JP5137228B2 (ja) | 2003-03-07 | 2013-02-06 | メルク・シャープ・アンド・ドーム・コーポレーション | 高コレステロール血症の処置のための置換アゼチジノン化合物、置換アゼチジノン処方物およびそれらの使用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3655656A (en) * | 1970-06-04 | 1972-04-11 | Lilly Co Eli | Crystalline cephalexin monohydrate |
JPS5672698A (en) * | 1979-11-14 | 1981-06-16 | Kyowa Hakko Kogyo Co Ltd | Preparation of optically active cephalosporin analogue |
MY103554A (en) * | 1987-10-07 | 1993-07-31 | Lilly Co Eli | Manohydrate and solvates of a new (beta)-lactam antibiotic. |
-
1988
- 1988-10-03 ZA ZA887409A patent/ZA887409B/xx unknown
- 1988-10-03 CA CA000579158A patent/CA1334970C/en not_active Expired - Fee Related
- 1988-10-03 MY MYPI88001103A patent/MY104063A/en unknown
- 1988-10-03 YU YU184588A patent/YU46699B/sh unknown
- 1988-10-03 DD DD88320417A patent/DD273634A5/de unknown
- 1988-10-03 EG EG506/88A patent/EG18529A/xx active
- 1988-10-04 FI FI884554A patent/FI884554A/fi not_active Application Discontinuation
- 1988-10-04 BG BG085594A patent/BG47036A3/xx unknown
- 1988-10-04 IL IL87905A patent/IL87905A/xx active Protection Beyond IP Right Term
- 1988-10-04 NZ NZ226450A patent/NZ226450A/xx unknown
- 1988-10-04 AR AR88312109A patent/AR248407A1/es active
- 1988-10-04 DK DK553788A patent/DK170070B1/da active IP Right Grant
- 1988-10-04 PT PT88662A patent/PT88662B/pt not_active IP Right Cessation
- 1988-10-04 JP JP63251712A patent/JP2641745B2/ja not_active Expired - Fee Related
- 1988-10-04 PH PH37636A patent/PH31002A/en unknown
- 1988-10-04 MX MX1327788A patent/MX13277A/es unknown
- 1988-10-04 AU AU23372/88A patent/AU598155B2/en not_active Expired
- 1988-10-05 EP EP88309261A patent/EP0311366B1/en not_active Expired - Lifetime
- 1988-10-05 NO NO88884416A patent/NO884416L/no unknown
- 1988-10-05 PL PL1988275093A patent/PL152022B1/pl unknown
- 1988-10-05 ES ES88309261T patent/ES2063049T3/es not_active Expired - Lifetime
- 1988-10-05 CN CN88109140A patent/CN1029966C/zh not_active Expired - Lifetime
- 1988-10-05 AT AT88309261T patent/ATE103916T1/de not_active IP Right Cessation
- 1988-10-05 KR KR1019880012961A patent/KR970002637B1/ko not_active IP Right Cessation
- 1988-10-05 HU HU885171A patent/HU206348B/hu unknown
- 1988-10-05 SU SU884356543A patent/SU1731058A3/ru active
- 1988-10-05 UA UA4356543A patent/UA19149A/uk unknown
- 1988-10-05 IE IE301588A patent/IE62108B1/en not_active IP Right Cessation
- 1988-10-05 OA OA59444A patent/OA08958A/xx unknown
- 1988-10-05 DE DE3888913T patent/DE3888913T2/de not_active Expired - Lifetime
- 1988-10-06 CS CS886666A patent/CS270594B2/cs not_active IP Right Cessation
-
1997
- 1997-02-05 HK HK15497A patent/HK15497A/xx not_active IP Right Cessation
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