BG37991A3 - Method for stabilizing lyophylized preparation containing beta- lactamic antibiotic - Google Patents

Method for stabilizing lyophylized preparation containing beta- lactamic antibiotic

Info

Publication number
BG37991A3
BG37991A3 BG8152598A BG5259881A BG37991A3 BG 37991 A3 BG37991 A3 BG 37991A3 BG 8152598 A BG8152598 A BG 8152598A BG 5259881 A BG5259881 A BG 5259881A BG 37991 A3 BG37991 A3 BG 37991A3
Authority
BG
Bulgaria
Prior art keywords
lyophylized
stabilizing
preparation containing
containing beta
lactamic
Prior art date
Application number
BG8152598A
Other languages
English (en)
Inventor
Hirai
Shima
Original Assignee
Shionogi & Co Ltd,Jp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co Ltd,Jp filed Critical Shionogi & Co Ltd,Jp
Publication of BG37991A3 publication Critical patent/BG37991A3/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BG8152598A 1980-06-23 1981-06-23 Method for stabilizing lyophylized preparation containing beta- lactamic antibiotic BG37991A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8578980A JPS5711909A (en) 1980-06-23 1980-06-23 Stable freeze-dried preparation of beta-lactam

Publications (1)

Publication Number Publication Date
BG37991A3 true BG37991A3 (en) 1985-09-16

Family

ID=13868648

Family Applications (1)

Application Number Title Priority Date Filing Date
BG8152598A BG37991A3 (en) 1980-06-23 1981-06-23 Method for stabilizing lyophylized preparation containing beta- lactamic antibiotic

Country Status (31)

Country Link
US (1) US4418058A (nl)
JP (1) JPS5711909A (nl)
KR (1) KR840000693B1 (nl)
AR (1) AR230007A1 (nl)
AT (1) AT380790B (nl)
AU (1) AU541627B2 (nl)
BE (1) BE889351A (nl)
BG (1) BG37991A3 (nl)
CA (1) CA1164801A (nl)
CH (1) CH648210A5 (nl)
CS (1) CS221835B2 (nl)
DD (1) DD159879A5 (nl)
DE (1) DE3124592A1 (nl)
DK (1) DK158443C (nl)
ES (1) ES503283A0 (nl)
FI (1) FI75490C (nl)
FR (1) FR2484835A1 (nl)
GB (1) GB2078737B (nl)
GR (1) GR75646B (nl)
HU (1) HU183494B (nl)
IE (1) IE51331B1 (nl)
IL (1) IL63136A (nl)
IT (1) IT1144812B (nl)
NL (1) NL191777C (nl)
NO (1) NO156036C (nl)
NZ (1) NZ197414A (nl)
PT (1) PT73239B (nl)
RO (1) RO82720B (nl)
SE (1) SE460702B (nl)
YU (1) YU44416B (nl)
ZA (1) ZA814203B (nl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS597193A (ja) * 1982-07-02 1984-01-14 Shionogi & Co Ltd マロニルメチル基の異性化方法
JPS6045514A (ja) * 1983-08-22 1985-03-12 Shionogi & Co Ltd 安定な抗菌性凍結乾燥製剤
US4797388A (en) * 1984-05-21 1989-01-10 Cetus Corporation Pharmaceutical compositions with galactitol as carrier
US4891391A (en) * 1985-01-03 1990-01-02 Morton Thiokol, Inc. Compositions containing antimicrobial agents in combination with stabilizers
US4816568A (en) * 1986-05-16 1989-03-28 International Minerals & Chemical Corp. Stabilization of growth hormones
DE3801179A1 (de) * 1988-01-18 1989-07-27 Hoechst Ag Stabilisierung von cephalosporinderivaten durch trocknung mit einem stabilisator sowie stabile zubereitungsformen mit cephalosporinderivaten
CN1556712A (zh) * 2000-07-13 2004-12-22 ��һ��������ҩ��ʽ���� 含dds化合物的药用组合物
US7378408B2 (en) * 2001-11-30 2008-05-27 Pfizer Inc. Methods of treatment and formulations of cephalosporin
EP2777705A1 (en) 2013-03-15 2014-09-17 Cubist Pharmaceuticals, Inc. Ceftolozane antibiotic compositions
US20140274993A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Ceftolozane-tazobactam pharmaceutical compositions
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
US10376496B2 (en) 2013-09-09 2019-08-13 Merck, Sharp & Dohme Corp. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US20150094293A1 (en) 2013-09-27 2015-04-02 Calixa Therapeutics, Inc. Solid forms of ceftolozane

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS532931B2 (nl) * 1973-12-05 1978-02-01
US3928592A (en) * 1974-02-22 1975-12-23 Lilly Co Eli Antibiotic pharmaceutical compositions
US3993753A (en) * 1974-08-26 1976-11-23 American Home Products Corporation Anhydrous ampicillin stabilization and resultant compositions
GB1463563A (en) * 1974-10-10 1977-02-02 Beecham Group Ltd Pharmaceutical compositions
JPS5151511A (en) * 1974-10-25 1976-05-07 Tooru Tatsuhara Aminosanseizai no anteikaho
US4180571A (en) * 1976-03-25 1979-12-25 Shionogi & Co., Ltd. Arylmalonamido-1-oxadethiacephalosporins
JPS532931A (en) * 1976-06-30 1978-01-12 Saraya Kk Toilet bowl cleaning method
BE861876A (fr) * 1976-12-17 1978-06-15 Scherico Ltd Nouvelles formulations d'antibiotiques beta-lactame leur procede de preparation, melange antibiotique injectable ainsi que son procede de preparation
JPS53104722A (en) * 1977-02-19 1978-09-12 Tsumura Juntendo Kk Production of powder for making herb medicine liquid agent
CA1127450A (en) * 1978-08-26 1982-07-13 Gordon L. Mcglennon Load multiplying mechanisms
US4259485A (en) * 1979-04-24 1981-03-31 Eli Lilly And Company Crystallization process

Also Published As

Publication number Publication date
IT8167863A0 (it) 1981-06-22
SE460702B (sv) 1989-11-13
PT73239B (en) 1982-07-22
ES8203887A1 (es) 1982-04-01
ES503283A0 (es) 1982-04-01
AR230007A1 (es) 1984-02-29
ZA814203B (en) 1982-09-29
NO156036B (no) 1987-04-06
GB2078737A (en) 1982-01-13
YU157381A (en) 1984-10-31
FI811948L (fi) 1981-12-24
CH648210A5 (de) 1985-03-15
NO156036C (no) 1987-07-15
FI75490C (fi) 1988-07-11
JPS5711909A (en) 1982-01-21
RO82720A (ro) 1984-05-23
FR2484835A1 (fr) 1981-12-24
US4418058A (en) 1983-11-29
FI75490B (fi) 1988-03-31
CA1164801A (en) 1984-04-03
NL191777B (nl) 1996-04-01
DE3124592A1 (de) 1982-02-11
AT380790B (de) 1986-07-10
SE8103904L (sv) 1981-12-24
KR840000693B1 (ko) 1984-05-21
YU44416B (en) 1990-08-31
DE3124592C2 (nl) 1990-12-20
PT73239A (en) 1981-07-01
DK158443C (da) 1990-10-08
NL191777C (nl) 1996-08-02
GR75646B (nl) 1984-08-02
IE51331B1 (en) 1986-12-10
BE889351A (fr) 1981-10-16
KR830005848A (ko) 1983-09-14
IL63136A (en) 1984-07-31
IT1144812B (it) 1986-10-29
NZ197414A (en) 1984-10-19
AU7209781A (en) 1983-01-06
DK274981A (da) 1981-12-24
NL8102943A (nl) 1982-01-18
DK158443B (da) 1990-05-21
AU541627B2 (en) 1985-01-17
ATA278881A (de) 1985-12-15
CS221835B2 (en) 1983-04-29
IE811347L (en) 1981-12-23
HU183494B (en) 1984-05-28
DD159879A5 (de) 1983-04-13
FR2484835B1 (nl) 1983-07-01
JPS6364405B2 (nl) 1988-12-12
IL63136A0 (en) 1981-09-13
RO82720B (ro) 1984-07-30
GB2078737B (en) 1984-03-14
NO812090L (no) 1981-12-28

Similar Documents

Publication Publication Date Title
BG37528A3 (en) Method for preparing 4- aminophenyl- aminophenyl- ammonium- tridecylphosphonate
EG15446A (en) Method of preparation 2-amino-3-cabethoxyamino-6-(fluro-benzylamino)-pyridine-maleate
DE3067906D1 (en) Method for the preparation of bis-styrylbenzenes
BG35330A3 (en) Method for preparing 3- iodine- methylcephalosporines
DE3061645D1 (en) Method for preparing azolyl-vinyl-ketones
BG37991A3 (en) Method for stabilizing lyophylized preparation containing beta- lactamic antibiotic
ZA815428B (en) Polycarbonate compositions and method for preparing
JPS57111549A (en) Copier-test method
BG36939A3 (en) Method for preparing macrolide
JPS5758696A (en) Macrolide compound
BG44208A3 (en) Method for preparation of enduracydine
DE3162511D1 (en) Method for the preparation of amino-nitriles
BG35044A3 (en) Method for preparing 1- oxa- beta- lactamic antibiotics
DE3173028D1 (en) Antibiotic a-4696 factor g
JPS5785858A (en) Azocoupling method
ZA812016B (en) Method for preparing thermoelastomeric three-biock copolymrs
AU536543B2 (en) Method
DE3160945D1 (en) Method for the preparation of (e)-4-bromo-2-methylbut-2-en-1-al
BG36790A3 (en) Method for preparing macrolides
GB8331971D0 (en) Fermentation method
JPS56155589A (en) Metallizing method
DE3170183D1 (en) Antibiotic 5057b
AU539947B2 (en) Method
AU537678B2 (en) Method
AU524415B2 (en) Method