BG36200A3 - Метод за получаване на винбластин 3-/2-хлоретил/- карбоксамиди - Google Patents

Метод за получаване на винбластин 3-/2-хлоретил/- карбоксамиди

Info

Publication number
BG36200A3
BG36200A3 BG051306A BG5130681A BG36200A3 BG 36200 A3 BG36200 A3 BG 36200A3 BG 051306 A BG051306 A BG 051306A BG 5130681 A BG5130681 A BG 5130681A BG 36200 A3 BG36200 A3 BG 36200A3
Authority
BG
Bulgaria
Prior art keywords
carboxamides
vinblastine
chloroethyl
preparation
formulated
Prior art date
Application number
BG051306A
Other languages
Bulgarian (bg)
English (en)
Inventor
Jean Miller
Gerald Gutowski
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of BG36200A3 publication Critical patent/BG36200A3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/02—Ergot alkaloids of the cyclic peptide type
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BG051306A 1980-03-20 1981-03-20 Метод за получаване на винбластин 3-/2-хлоретил/- карбоксамиди BG36200A3 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/132,246 US4357334A (en) 1980-03-20 1980-03-20 Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms

Publications (1)

Publication Number Publication Date
BG36200A3 true BG36200A3 (bg) 1984-09-14

Family

ID=22453135

Family Applications (1)

Application Number Title Priority Date Filing Date
BG051306A BG36200A3 (bg) 1980-03-20 1981-03-20 Метод за получаване на винбластин 3-/2-хлоретил/- карбоксамиди

Country Status (28)

Country Link
US (1) US4357334A (OSRAM)
EP (1) EP0036762B1 (OSRAM)
JP (1) JPS56145293A (OSRAM)
KR (1) KR840002146B1 (OSRAM)
AR (1) AR228863A1 (OSRAM)
AT (1) ATE9761T1 (OSRAM)
AU (1) AU539564B2 (OSRAM)
BG (1) BG36200A3 (OSRAM)
CA (1) CA1159055A (OSRAM)
DD (1) DD157558A5 (OSRAM)
DE (1) DE3166544D1 (OSRAM)
DK (1) DK124281A (OSRAM)
EG (1) EG15247A (OSRAM)
ES (2) ES500536A0 (OSRAM)
FI (1) FI810856A7 (OSRAM)
GB (1) GB2072184B (OSRAM)
GR (1) GR73870B (OSRAM)
HU (1) HU185247B (OSRAM)
IE (1) IE51034B1 (OSRAM)
IL (1) IL62378A (OSRAM)
NZ (1) NZ196511A (OSRAM)
PH (1) PH16213A (OSRAM)
PL (1) PL230226A1 (OSRAM)
PT (1) PT72695B (OSRAM)
RO (2) RO85813B (OSRAM)
SU (2) SU1017172A3 (OSRAM)
YU (1) YU66281A (OSRAM)
ZA (1) ZA811733B (OSRAM)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE64396T1 (de) * 1983-04-29 1991-06-15 Omnichem Sa Konjugierte vinblastin-verbindungen und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
HUT76925A (hu) * 1995-04-04 1998-01-28 MTA Enzimológiai Intézet Bisz-indol-származékok, eljárás előállításukra és az azokat tartalmazó gyógyszerkészítmények

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR204004A1 (es) 1973-04-02 1975-11-12 Lilly Co Eli Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
IL48685A (en) 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine
GR69783B (OSRAM) 1976-09-08 1982-07-07 Lilly Co Eli
US4096148A (en) * 1976-12-06 1978-06-20 Eli Lilly And Company Oxazolidinedione derivatives of Vinca alkaloids
USRE30561E (en) 1976-12-06 1981-03-31 Eli Lilly And Company Vinca alkaloid intermediates
US4160767A (en) * 1976-12-06 1979-07-10 Eli Lilly And Company Vinca alkaloid intermediates
US4191688A (en) * 1977-08-08 1980-03-04 Eli Lilly And Company Amides of leurosine, leuroformine, desacetylleurosine and desacetylleuroformine
US4203898A (en) * 1977-08-29 1980-05-20 Eli Lilly And Company Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids

Also Published As

Publication number Publication date
IE810609L (en) 1981-09-20
ES8206538A1 (es) 1982-08-16
IL62378A (en) 1984-03-30
RO82171B (ro) 1983-06-30
EP0036762A2 (en) 1981-09-30
SU1017172A3 (ru) 1983-05-07
SU1200851A3 (ru) 1985-12-23
EG15247A (en) 1986-03-31
EP0036762A3 (en) 1981-10-07
AU539564B2 (en) 1984-10-04
PH16213A (en) 1983-08-05
DK124281A (da) 1981-09-21
RO85813A (ro) 1984-11-25
DE3166544D1 (en) 1984-11-15
PL230226A1 (OSRAM) 1982-03-15
GB2072184A (en) 1981-09-30
RO82171A (ro) 1983-07-07
ZA811733B (en) 1982-10-27
PT72695B (en) 1982-03-24
DD157558A5 (de) 1982-11-17
CA1159055A (en) 1983-12-20
ATE9761T1 (de) 1984-10-15
AU6858181A (en) 1981-09-24
EP0036762B1 (en) 1984-10-10
GB2072184B (en) 1984-01-11
KR840002146B1 (ko) 1984-11-23
RO85813B (ro) 1984-11-30
AR228863A1 (es) 1983-04-29
PT72695A (en) 1981-04-01
NZ196511A (en) 1983-09-30
IL62378A0 (en) 1981-05-20
ES8302009A1 (es) 1982-12-16
ES509581A0 (es) 1982-12-16
GR73870B (OSRAM) 1984-05-09
HU185247B (en) 1984-12-28
KR830005248A (ko) 1983-08-03
ES500536A0 (es) 1982-08-16
FI810856L (fi) 1981-09-21
US4357334A (en) 1982-11-02
FI810856A7 (fi) 1981-09-21
JPS56145293A (en) 1981-11-11
IE51034B1 (en) 1986-09-17
YU66281A (en) 1983-10-31

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