BG24813A4 - Метод за получаване на 2-тетрахидрофурфурил-6,7- бензоморфани и техните соли - Google Patents

Метод за получаване на 2-тетрахидрофурфурил-6,7- бензоморфани и техните соли

Info

Publication number
BG24813A4
BG24813A4 BG030537A BG3053775A BG24813A4 BG 24813 A4 BG24813 A4 BG 24813A4 BG 030537 A BG030537 A BG 030537A BG 3053775 A BG3053775 A BG 3053775A BG 24813 A4 BG24813 A4 BG 24813A4
Authority
BG
Bulgaria
Prior art keywords
benzomorphanes
tetrahydrofurfuryl
salts
preparation
Prior art date
Application number
BG030537A
Other languages
Bulgarian (bg)
English (en)
Inventor
Herbert Merz
Adolf Langbein
Gerhard Walther
Klaus Stockhaus
Original Assignee
C.H.Boehringer Sohn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C.H.Boehringer Sohn filed Critical C.H.Boehringer Sohn
Publication of BG24813A4 publication Critical patent/BG24813A4/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
BG030537A 1974-03-09 1975-03-07 Метод за получаване на 2-тетрахидрофурфурил-6,7- бензоморфани и техните соли BG24813A4 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2411382A DE2411382C3 (de) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung

Publications (1)

Publication Number Publication Date
BG24813A4 true BG24813A4 (bg) 1978-05-12

Family

ID=5909593

Family Applications (3)

Application Number Title Priority Date Filing Date
BG029183A BG25087A3 (bg) 1974-03-09 1975-03-07 Метод за получаване на 2-тетрахидрофупфупил-6,7 бензоморфани и техните соли
BG030537A BG24813A4 (bg) 1974-03-09 1975-03-07 Метод за получаване на 2-тетрахидрофурфурил-6,7- бензоморфани и техните соли
BG030538A BG24814A4 (bg) 1974-03-09 1975-03-07 Метод за получаване на 2-тетрахидрофурфурил-6,7 бензоморфани и техните соли

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BG029183A BG25087A3 (bg) 1974-03-09 1975-03-07 Метод за получаване на 2-тетрахидрофупфупил-6,7 бензоморфани и техните соли

Family Applications After (1)

Application Number Title Priority Date Filing Date
BG030538A BG24814A4 (bg) 1974-03-09 1975-03-07 Метод за получаване на 2-тетрахидрофурфурил-6,7 бензоморфани и техните соли

Country Status (25)

Country Link
JP (1) JPS5827275B2 (enExample)
AT (1) AT344332B (enExample)
BE (1) BE826440A (enExample)
BG (3) BG25087A3 (enExample)
CA (1) CA1049511A (enExample)
CH (8) CH612425A5 (enExample)
CS (1) CS188221B2 (enExample)
DD (1) DD119236A5 (enExample)
DE (1) DE2411382C3 (enExample)
DK (1) DK137188C (enExample)
ES (6) ES440346A1 (enExample)
FI (1) FI63571C (enExample)
FR (1) FR2262984B1 (enExample)
GB (1) GB1496418A (enExample)
HU (1) HU177408B (enExample)
IE (1) IE40945B1 (enExample)
IL (1) IL46760A (enExample)
NL (1) NL7502724A (enExample)
NO (1) NO141800C (enExample)
PH (1) PH14127A (enExample)
PL (3) PL93700B1 (enExample)
RO (2) RO69617A (enExample)
SE (1) SE421919B (enExample)
SU (3) SU577982A3 (enExample)
ZA (1) ZA751394B (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
WO1996028412A1 (en) * 1995-03-10 1996-09-19 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
US8575156B2 (en) 2007-07-26 2013-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1
CL2008003407A1 (es) 2007-11-16 2010-01-11 Boehringer Ingelheim Int Compuestos derivados de aril- y heteroarilcarbonilo de heterobiciclo sustituido; composicion farmaceutica; procedimiento de preparacion; y su uso en el tratamiento y/o prevencion de trastornos metabolicos, mediado por la inhibicion de la enzima hsd-1.
WO2009075835A1 (en) 2007-12-11 2009-06-18 Vitae Pharmaceutical, Inc CYCLIC UREA INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
JP5490020B2 (ja) 2008-01-24 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状カルバゼート及びセミカルバジドインヒビター
US8598160B2 (en) 2008-02-15 2013-12-03 Vitae Pharmaceuticals, Inc. Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
NZ588954A (en) 2008-05-01 2012-08-31 Vitae Pharmaceuticals Inc Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW201004945A (en) 2008-05-01 2010-02-01 Vitae Pharmaceuticals Inc Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2009134387A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW200950780A (en) 2008-05-13 2009-12-16 Boehringer Ingelheim Int Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
CN104327062A (zh) 2008-07-25 2015-02-04 贝林格尔·英格海姆国际有限公司 11β-羟基类固醇脱氢酶1的环状抑制剂
TW201016691A (en) 2008-07-25 2010-05-01 Boehringer Ingelheim Int Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
WO2011011123A1 (en) 2009-06-11 2011-01-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
TWI531571B (zh) 2009-11-06 2016-05-01 維它藥物公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜芳基羰基衍生物
JP5860042B2 (ja) 2010-06-16 2016-02-16 ヴァイティー ファーマシューティカルズ，インコーポレイテッド 置換５、６及び７員複素環、そのような化合物を含有する医薬及びそれらの使用
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
JP2014524438A (ja) 2011-08-17 2014-09-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング インデノピリジン誘導体

Also Published As

Publication number Publication date
ES440348A1 (es) 1977-06-01
DD119236A5 (enExample) 1976-04-12
FR2262984A1 (enExample) 1975-10-03
SE7502592L (enExample) 1975-09-10
FI63571C (fi) 1983-07-11
ES440349A1 (es) 1977-03-01
CS188221B2 (en) 1979-02-28
ATA153875A (de) 1977-11-15
FI63571B (fi) 1983-03-31
AU7894275A (en) 1976-09-16
PL93499B1 (enExample) 1977-05-30
BG25087A3 (bg) 1978-07-12
ES440347A1 (es) 1977-06-01
IE40945L (en) 1975-09-09
ES440345A1 (es) 1977-03-01
NO141800B (no) 1980-02-04
BE826440A (fr) 1975-09-08
ES440350A1 (es) 1977-03-16
SU577982A3 (ru) 1977-10-25
IE40945B1 (en) 1979-09-12
PL93700B1 (enExample) 1977-06-30
GB1496418A (en) 1977-12-30
CH622017A5 (en) 1981-03-13
CH622015A5 (en) 1981-03-13
AT344332B (de) 1978-07-10
ZA751394B (en) 1976-11-24
FI750652A7 (enExample) 1975-09-10
CA1049511A (en) 1979-02-27
CH620681A5 (en) 1980-12-15
CH620439A5 (en) 1980-11-28
JPS5827275B2 (ja) 1983-06-08
IL46760A (en) 1978-12-17
RO69617A (ro) 1980-08-15
SU577983A3 (ru) 1977-10-25
PL93699B1 (enExample) 1977-06-30
DK137188B (da) 1978-01-30
RO70051A (ro) 1980-12-30
DE2411382A1 (de) 1975-09-18
NL7502724A (nl) 1975-09-11
CH622014A5 (en) 1981-03-13
DE2411382C3 (de) 1979-09-06
HU177408B (en) 1981-10-28
DK137188C (da) 1978-07-03
DE2411382B2 (de) 1979-01-18
JPS50123675A (enExample) 1975-09-29
CH612425A5 (en) 1979-07-31
IL46760A0 (en) 1975-05-22
DK92975A (enExample) 1975-09-10
FR2262984B1 (enExample) 1978-07-28
NO750773L (enExample) 1975-09-10
PH14127A (en) 1981-02-26
SE421919B (sv) 1982-02-08
CH622016A5 (en) 1981-03-13
CH620440A5 (en) 1980-11-28
NO141800C (no) 1980-06-04
BG24814A4 (bg) 1978-05-12
ES440346A1 (es) 1977-03-01
SU588916A3 (ru) 1978-01-15

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